IRF2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description interferon regulatory factor 2|IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3660)
External Link https://ncbi.nlm.nih.gov/gene/3660
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Genes

499 genes differentially expressed following the IRF2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0338135
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0133644
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.01286
FLRT3 fibronectin leucine rich transmembrane protein 3 0.0119406
C3ORF14 chromosome 3 open reading frame 14 0.0116491
PBX3 pre-B-cell leukemia homeobox 3 0.0110441
SMC1A structural maintenance of chromosomes 1A 0.0108572
AUTS2 autism susceptibility candidate 2 0.010604
SCGB2A1 secretoglobin, family 2A, member 1 0.010258
MAL mal, T-cell differentiation protein 0.00989525
WDR7 WD repeat domain 7 0.0097662
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00974211
MYH10 myosin, heavy chain 10, non-muscle 0.0097255
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00960046
ZIC1 Zic family member 1 0.00958961
CHGB chromogranin B 0.0095043
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.00948449
LAMP3 lysosomal-associated membrane protein 3 0.00937523
CLEC11A C-type lectin domain family 11, member A 0.00936305
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00928726
OXTR oxytocin receptor 0.00920764
ZNF160 zinc finger protein 160 0.00906611
DYNLL1 dynein, light chain, LC8-type 1 0.00903361
SPRY2 sprouty homolog 2 (Drosophila) 0.00902654
THBS2 thrombospondin 2 0.00892489
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00887004
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00885529
HSPA8 heat shock 70kDa protein 8 0.00871665
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00859725
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00856825
COG7 component of oligomeric golgi complex 7 0.00850743
PEG3 paternally expressed 3 0.00846016
THBS4 thrombospondin 4 0.00838871
SRPX sushi-repeat containing protein, X-linked 0.00833918
ADGRL2 adhesion G protein-coupled receptor L2 0.00823318
SLPI secretory leukocyte peptidase inhibitor 0.008205
HOXC6 homeobox C6 0.00814324
ASS1 argininosuccinate synthase 1 0.00806721
BEX4 brain expressed, X-linked 4 0.00806404
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00801805
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00798898
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.00798634
NSG1 neuron specific gene family member 1 0.00795088
PUDP pseudouridine 5'-phosphatase 0.00794783
ANGPT1 angiopoietin 1 0.00794446
MX1 MX dynamin-like GTPase 1 0.00788174
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00785033
KLF6 Kruppel-like factor 6 0.00785011
TYRP1 tyrosinase-related protein 1 0.00781605
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.00781486
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00779891
DLK1 delta-like 1 homolog (Drosophila) 0.00777725
FAR2 fatty acyl CoA reductase 2 0.00775153
QPRT quinolinate phosphoribosyltransferase 0.00773725
TUBB2B tubulin, beta 2B class IIb 0.00769802
ADCY1 adenylate cyclase 1 (brain) 0.00763938
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00763162
RRAGD Ras-related GTP binding D 0.00757452
ISG15 ISG15 ubiquitin-like modifier 0.00755404
TMSB15A thymosin beta 15a 0.00755129
HOMER1 homer scaffolding protein 1 0.00751612
MEN1 multiple endocrine neoplasia I 0.00748755
MRPS16 mitochondrial ribosomal protein S16 0.00743476
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00742843
ZMAT3 zinc finger, matrin-type 3 0.00742178
GCH1 GTP cyclohydrolase 1 0.00741917
KRT23 keratin 23, type I 0.00738469
HSPA1A heat shock 70kDa protein 1A 0.00730626
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.00724979
ITM2A integral membrane protein 2A 0.00724174
NCALD neurocalcin delta 0.00724038
SCGB2A2 secretoglobin, family 2A, member 2 0.00720751
BPIFA1 BPI fold containing family A, member 1 0.00720231
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00715664
TFPI2 tissue factor pathway inhibitor 2 0.00713936
ZNF721 zinc finger protein 721 0.00711965
SMYD2 SET and MYND domain containing 2 0.00707148
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 0.00706051
PROM1 prominin 1 0.00703769
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00702746
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.00701688
NEFM neurofilament, medium polypeptide 0.0069728
SYNGR3 synaptogyrin 3 0.0069492
NEFH neurofilament, heavy polypeptide 0.00693819
SKAP2 src kinase associated phosphoprotein 2 0.00692598
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00692123
AKAP12 A kinase (PRKA) anchor protein 12 0.00689137
TPBG trophoblast glycoprotein 0.00679037
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.00675564
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00673067
MT1E metallothionein 1E 0.00668341
LEF1 lymphoid enhancer-binding factor 1 0.00664917
SCG5 secretogranin V 0.00664427
CXCL8 chemokine (C-X-C motif) ligand 8 0.00662867
ADGRF5 adhesion G protein-coupled receptor F5 0.00660115
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00656806
NUP210 nucleoporin 210kDa 0.00654828
SNX11 sorting nexin 11 0.00654807
RELN reelin 0.00652372
C7 complement component 7 0.00652025
G0S2 G0/G1 switch 2 0.00651786
DNTT DNA nucleotidylexotransferase 0.00650028
FRMD4B FERM domain containing 4B 0.00647432
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00646365
COX5A cytochrome c oxidase subunit Va 0.00645482
MGP matrix Gla protein 0.00643425
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.0064208
DTX4 deltex 4, E3 ubiquitin ligase 0.00640733
GUSBP3 glucuronidase, beta pseudogene 3 0.0063968
RET ret proto-oncogene 0.00638117
STMN2 stathmin 2 0.00636311
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00635205
SPRY4 sprouty homolog 4 (Drosophila) 0.00633672
ADM adrenomedullin 0.00633509
MMP9 matrix metallopeptidase 9 0.00632346
PEG10 paternally expressed 10 0.00631824
PLIN3 perilipin 3 0.00630285
HAUS2 HAUS augmin-like complex, subunit 2 0.00625995
RETREG1 reticulophagy regulator 1 0.00625134
MT1HL1 metallothionein 1H-like 1 0.00625039
CRABP2 cellular retinoic acid binding protein 2 0.00616327
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00615676
VPREB1 pre-B lymphocyte 1 0.00611429
LGALSL lectin, galactoside-binding-like 0.00611404
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.00610974
GNAS GNAS complex locus 0.00610366
ATF3 activating transcription factor 3 0.00609777
TREM1 triggering receptor expressed on myeloid cells 1 0.00605614
PITX3 paired-like homeodomain 3 0.00605531
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 0.00605089
OGDHL oxoglutarate dehydrogenase-like 0.00603063
INA internexin neuronal intermediate filament protein, alpha 0.0060241
ATP5F1E ATP synthase F1 subunit epsilon 0.00601711
BEX1 brain expressed, X-linked 1 0.0059947
FABP4 fatty acid binding protein 4, adipocyte 0.00599393
NRN1 neuritin 1 0.00597759
PRR11 proline rich 11 0.0059618
ALOX15B arachidonate 15-lipoxygenase, type B 0.00592761
CXADR coxsackie virus and adenovirus receptor 0.00590661
THBS1 thrombospondin 1 0.00589311
FOXD1 forkhead box D1 0.00585118
LMCD1 LIM and cysteine-rich domains 1 0.00585116
SYT1 synaptotagmin I 0.0058487
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00584484
COLEC11 collectin sub-family member 11 0.00584458
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00583885
RPS25 ribosomal protein S25 0.00583692
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00580802
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 0.00579267
STS steroid sulfatase (microsomal), isozyme S 0.00578875
CCDC6 coiled-coil domain containing 6 0.00576804
MT1F metallothionein 1F 0.00576314
SV2A synaptic vesicle glycoprotein 2A 0.00574525
MGMT O-6-methylguanine-DNA methyltransferase 0.00574218
SMS spermine synthase 0.0057292
ELL2 elongation factor, RNA polymerase II, 2 0.00571299
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.00571182
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.00570449
TM4SF1 transmembrane 4 L six family member 1 0.00570265
TTC39A tetratricopeptide repeat domain 39A 0.00570203
LRRN3 leucine rich repeat neuronal 3 0.0056881
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.00568623
ATP5MG ATP synthase membrane subunit g 0.00566677
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.00565546
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00564565
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00560302
TAOK1 TAO kinase 1 0.00559918
LAMP5 lysosomal-associated membrane protein family, member 5 0.00559795
RSL1D1 ribosomal L1 domain containing 1 0.00559409
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00559353
UBFD1 ubiquitin family domain containing 1 0.00558661
MYH11 myosin, heavy chain 11, smooth muscle 0.00558404
PLLP plasmolipin 0.00558322
SYBU syntabulin (syntaxin-interacting) 0.00556473
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.00555688
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.0055496
HOMER2 homer scaffolding protein 2 0.00552671
KIF3B kinesin family member 3B 0.0055227
BARD1 BRCA1 associated RING domain 1 0.00552067
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00550011
RGCC regulator of cell cycle 0.0054991
UGCG UDP-glucose ceramide glucosyltransferase 0.00549169
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00549107
LBH limb bud and heart development 0.00548734
STK10 serine/threonine kinase 10 0.0054765
STEAP3 STEAP family member 3, metalloreductase 0.00547601
LAT2 linker for activation of T cells family, member 2 0.00547263
MEIS1 Meis homeobox 1 0.00544786
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00543039
ZNF669 zinc finger protein 669 0.00542837
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00542012
RIMBP2 RIMS binding protein 2 0.00540474
AAMDC adipogenesis associated, Mth938 domain containing 0.00538183
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.00537819
RAB6B RAB6B, member RAS oncogene family 0.00537574
IRX5 iroquois homeobox 5 0.00535402
MMP1 matrix metallopeptidase 1 0.0053425
ABHD5 abhydrolase domain containing 5 0.00533101
SEPTIN6 septin 6 0.00532934
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00532414
TENT5A terminal nucleotidyltransferase 5A 0.00531735
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00530383
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00527589
ZNF652 zinc finger protein 652 0.00526908
TRIM29 tripartite motif containing 29 0.00525817
ICA1 islet cell autoantigen 1, 69kDa 0.00523825
TWIST1 twist family bHLH transcription factor 1 0.00522628
PECR peroxisomal trans-2-enoyl-CoA reductase 0.00521779
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00521157
FBXW12 F-box and WD repeat domain containing 12 0.00520911
MAP9 microtubule-associated protein 9 0.00520094
SKAP1 src kinase associated phosphoprotein 1 0.00518183
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00517979
ABHD2 abhydrolase domain containing 2 0.0051651
LCN2 lipocalin 2 0.00515933
LOC283683 uncharacterized LOC283683 0.00515842
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.0051556
TPX2 TPX2, microtubule-associated 0.00514218
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00513613
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00512822
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00511914
CTSC cathepsin C 0.00511833
ANO10 anoctamin 10 0.00511147
AQP3 aquaporin 3 (Gill blood group) 0.00510605
ZNF611 zinc finger protein 611 0.00508227
MT1H metallothionein 1H 0.00506914
EMP2 epithelial membrane protein 2 0.00506341
PTDSS1 phosphatidylserine synthase 1 0.00505288
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00504035
TAGLN3 transgelin 3 0.00503551
SLIRP SRA stem-loop interacting RNA binding protein 0.00503515
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 0.00503183
SASH3 SAM and SH3 domain containing 3 0.0050309
DMAC2L distal membrane arm assembly component 2 like 0.00502697
FXR1 fragile X mental retardation, autosomal homolog 1 0.00501967
CLDN5 claudin 5 0.00501558
KIAA0100 KIAA0100 0.00501525
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.00500365
COL6A3 collagen, type VI, alpha 3 0.00499458
GMFG glia maturation factor, gamma 0.0049884
ZNF93 zinc finger protein 93 0.00495361
MT1X metallothionein 1X 0.00495126
DNM1L dynamin 1-like 0.00494793
PCOLCE procollagen C-endopeptidase enhancer 0.00494224
FOLR1 folate receptor 1 (adult) 0.0049357
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.00493463
NRIP3 nuclear receptor interacting protein 3 0.00492791
ZMYND8 zinc finger, MYND-type containing 8 0.00492087
CYB5A cytochrome b5 type A (microsomal) 0.00490682
CFDP1 craniofacial development protein 1 0.00490438

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0179529
JCHAIN joining chain of multimeric IgA and IgM -0.0161733
VCAM1 vascular cell adhesion molecule 1 -0.0147353
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0137949
WASHC4 WASH complex subunit 4 -0.0129429
OLFM4 olfactomedin 4 -0.0122646
MET MET proto-oncogene, receptor tyrosine kinase -0.0121759
EIF5A eukaryotic translation initiation factor 5A -0.0120646
HNMT histamine N-methyltransferase -0.0120041
AKR1C3 aldo-keto reductase family 1, member C3 -0.0118255
TMEM176B transmembrane protein 176B -0.0115586
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0115469
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0105816
SOX9 SRY (sex determining region Y)-box 9 -0.010476
PMP22 peripheral myelin protein 22 -0.0104415
GJA1 gap junction protein, alpha 1, 43kDa -0.0102425
TNS3 tensin 3 -0.0100378
GBP1 guanylate binding protein 1, interferon-inducible -0.00959292
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.0095911
EMP3 epithelial membrane protein 3 -0.0094832
STXBP2 syntaxin binding protein 2 -0.00931868
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00914553
MTMR11 myotubularin related protein 11 -0.00909623
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00905778
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00875617
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00873542
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00864387
C1S complement component 1, s subcomponent -0.00842583
PLPP3 phospholipid phosphatase 3 -0.00836285
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00835309
LUM lumican -0.0083419
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00830657
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00828607
RIN2 Ras and Rab interactor 2 -0.00824848
CTSB cathepsin B -0.00820222
TBX3 T-box 3 -0.00819672
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00815093
RXRA retinoid X receptor, alpha -0.00811365
PTCH1 patched 1 -0.0081046
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00803438
CHKB choline kinase beta -0.00796068
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.0079167
C1QA complement component 1, q subcomponent, A chain -0.00791343
CHPT1 choline phosphotransferase 1 -0.00791005
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00789991
DIPK1A divergent protein kinase domain 1A -0.00789744
NFE2L3 nuclear factor, erythroid 2-like 3 -0.00789473
MAGEB2 melanoma antigen family B2 -0.00789033
GSAP gamma-secretase activating protein -0.00788121
SUB1 SUB1 homolog (S. cerevisiae) -0.00786054
MMP11 matrix metallopeptidase 11 -0.00782201
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -0.00772149
KDM5D lysine (K)-specific demethylase 5D -0.00767551
CAV1 caveolin 1, caveolae protein, 22kDa -0.00764556
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00762728
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00758848
ADAMDEC1 ADAM-like, decysin 1 -0.00758574
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -0.00751151
NME3 NME/NM23 nucleoside diphosphate kinase 3 -0.00747585
METRN meteorin, glial cell differentiation regulator -0.00742984
CHN1 chimerin 1 -0.00738682
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00738059
CTSH cathepsin H -0.0073682
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00735018
AXL AXL receptor tyrosine kinase -0.00723699
DLD dihydrolipoamide dehydrogenase -0.007215
S100A10 S100 calcium binding protein A10 -0.0071793
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00710233
ASPH aspartate beta-hydroxylase -0.0070907
TGM2 transglutaminase 2 -0.00707787
PDE4B phosphodiesterase 4B, cAMP-specific -0.00707552
H1-0 H1.0 linker histone -0.00705587
GPX1 glutathione peroxidase 1 -0.00705256
SCRG1 stimulator of chondrogenesis 1 -0.00704937
TYMP thymidine phosphorylase -0.00704003
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00702508
TPM2 tropomyosin 2 (beta) -0.00701057
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0070095
TPSAB1 tryptase alpha/beta 1 -0.00700616
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00700373
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.00697707
FAM13A family with sequence similarity 13, member A -0.00690525
FADS3 fatty acid desaturase 3 -0.00688834
BPGM 2,3-bisphosphoglycerate mutase -0.00685493
TMEM176A transmembrane protein 176A -0.00684068
MMP12 matrix metallopeptidase 12 -0.00683265
BSG basigin (Ok blood group) -0.00683122
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00677062
REG3A regenerating islet-derived 3 alpha -0.00675694
MEX3D mex-3 RNA binding family member D -0.0067484
NKG7 natural killer cell granule protein 7 -0.00668836
GNLY granulysin -0.00668806
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00665397
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00662677
LOXL2 lysyl oxidase-like 2 -0.00661207
AMDHD2 amidohydrolase domain containing 2 -0.00659653
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00657913
HHEX hematopoietically expressed homeobox -0.00654176
ADAM9 ADAM metallopeptidase domain 9 -0.00650563
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00650171
FOXF1 forkhead box F1 -0.00648629
C1R complement component 1, r subcomponent -0.00648494
CPA3 carboxypeptidase A3 (mast cell) -0.00645782
GCLC glutamate-cysteine ligase, catalytic subunit -0.00645276
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00644089
TMEM259 transmembrane protein 259 -0.00643256
CLDND1 claudin domain containing 1 -0.00643108
KIAA0226L KIAA0226-like -0.00642578
IL10RA interleukin 10 receptor, alpha -0.00639748
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -0.00639585
EDRF1 erythroid differentiation regulatory factor 1 -0.00636115
TMEM106B transmembrane protein 106B -0.00635461
TPD52 tumor protein D52 -0.00633822
TPST2 tyrosylprotein sulfotransferase 2 -0.00633756
EREG epiregulin -0.00632527
CKAP4 cytoskeleton-associated protein 4 -0.00632159
ADIRF adipogenesis regulatory factor -0.00631739
PLAU plasminogen activator, urokinase -0.00631211
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00628139
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00626673
STAT4 signal transducer and activator of transcription 4 -0.00625078
ORC1 origin recognition complex, subunit 1 -0.00623571
ANKRD10 ankyrin repeat domain 10 -0.00621093
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00620013
TGFBI transforming growth factor, beta-induced, 68kDa -0.00618231
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00617599
G6PD glucose-6-phosphate dehydrogenase -0.00616722
IDO1 indoleamine 2,3-dioxygenase 1 -0.00616613
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00615493
CNN3 calponin 3, acidic -0.00612289
ITGA6 integrin, alpha 6 -0.00611257
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.0060967
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00604574
SRGN serglycin -0.0060092
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00600118
MTCL1 microtubule crosslinking factor 1 -0.00599838
CBR4 carbonyl reductase 4 -0.00599544
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00599358
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -0.00599075
SLAMF7 SLAM family member 7 -0.00598499
WNT5A wingless-type MMTV integration site family, member 5A -0.00596298
FNDC3B fibronectin type III domain containing 3B -0.00596287
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00595862
CLCN3 chloride channel, voltage-sensitive 3 -0.00594337
PDLIM4 PDZ and LIM domain 4 -0.00592267
TFEC transcription factor EC -0.00589703
ZBTB18 zinc finger and BTB domain containing 18 -0.00587288
C1QB complement component 1, q subcomponent, B chain -0.00586961
NLRP2 NLR family, pyrin domain containing 2 -0.00584673
TLR3 toll-like receptor 3 -0.00584277
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00582653
RTL8C retrotransposon Gag like 8C -0.00582435
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00577991
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00577468
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -0.00576539
IL7 interleukin 7 -0.0057379
P3H2 prolyl 3-hydroxylase 2 -0.0057342
CCN3 cellular communication network factor 3 -0.00571996
DUSP5 dual specificity phosphatase 5 -0.00571644
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00571591
IL2RB interleukin 2 receptor, beta -0.00570277
SATB2 SATB homeobox 2 -0.00569965
ZHX2 zinc fingers and homeoboxes 2 -0.00568844
TESK1 testis-specific kinase 1 -0.00568518
CENPB centromere protein B, 80kDa -0.00566583
CALD1 caldesmon 1 -0.00561958
PTPRD protein tyrosine phosphatase, receptor type, D -0.00561094
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00560259
IGFBP1 insulin-like growth factor binding protein 1 -0.00559736
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00559667
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00558073
MSX1 msh homeobox 1 -0.00557066
SOD2 superoxide dismutase 2, mitochondrial -0.0055669
COL6A2 collagen, type VI, alpha 2 -0.00555101
IL33 interleukin 33 -0.00553343
GZMK granzyme K (granzyme 3; tryptase II) -0.00553104
SLC38A1 solute carrier family 38, member 1 -0.00550733
FUCA1 fucosidase, alpha-L- 1, tissue -0.00550016
SDF4 stromal cell derived factor 4 -0.00549322
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -0.0054932
UBE2M ubiquitin-conjugating enzyme E2M -0.00548425
TMEM165 transmembrane protein 165 -0.00548177
CCNB1 cyclin B1 -0.00547603
TM9SF3 transmembrane 9 superfamily member 3 -0.00546695
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00545505
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00544635
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00543526
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00542616
SNCAIP synuclein, alpha interacting protein -0.00539994
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00539804
PRF1 perforin 1 (pore forming protein) -0.00538161
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00538012
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00536828
ACADVL acyl-CoA dehydrogenase, very long chain -0.00535254
LEPR leptin receptor -0.00533551
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) -0.00533217
MOCOS molybdenum cofactor sulfurase -0.00532536
CA2 carbonic anhydrase II -0.00531504
EZR ezrin -0.00531352
PITX1 paired-like homeodomain 1 -0.00531341
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.00530355
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00529575
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00529196
PHYH phytanoyl-CoA 2-hydroxylase -0.00526831
ATXN10 ataxin 10 -0.00526419
RNF146 ring finger protein 146 -0.00525775
TGFB1 transforming growth factor, beta 1 -0.00525559
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00525376
LTBP2 latent transforming growth factor beta binding protein 2 -0.00525326
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.00524621
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00524558
SDC3 syndecan 3 -0.00523898
WTAP Wilms tumor 1 associated protein -0.00523629
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00522398
ALOX5 arachidonate 5-lipoxygenase -0.00522329
BRD1 bromodomain containing 1 -0.00521111
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00519757
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00519379
TBL1X transducin (beta)-like 1X-linked -0.00518539
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00516191
CFB complement factor B -0.00516088
NOTCH2 notch 2 -0.00516049
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00516047
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00515892
DRAM1 DNA-damage regulated autophagy modulator 1 -0.0051556
SI sucrase-isomaltase (alpha-glucosidase) -0.00513899
PBX1 pre-B-cell leukemia homeobox 1 -0.00513126
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.005131
ARHGAP12 Rho GTPase activating protein 12 -0.00510615
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00509747
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00509715
NCOA2 nuclear receptor coactivator 2 -0.00508015
BTG1 B-cell translocation gene 1, anti-proliferative -0.00507354
FBLN1 fibulin 1 -0.00506564
COL5A1 collagen, type V, alpha 1 -0.00506462
IL32 interleukin 32 -0.00505558
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.0050454
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -0.00503004
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00500636
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.00499981
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.004989
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00497823
KLHDC2 kelch domain containing 2 -0.00497596
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00496438
TMEM184B transmembrane protein 184B -0.0049602
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00495296
GLUD1 glutamate dehydrogenase 1 -0.00494104
BIRC3 baculoviral IAP repeat containing 3 -0.00493784
DAPK1 death-associated protein kinase 1 -0.00490542