IRF2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description interferon regulatory factor 2|IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3660)
External Link http://www.ncbi.nlm.nih.gov/gene/3660
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Genes

33 interacting proteins for IRF2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APP amyloid beta (A4) precursor protein
ATG7 autophagy related 7
BRD7 bromodomain containing 7
CSNK2A1 casein kinase 2, alpha 1 polypeptide
EP300 E1A binding protein p300
FKBP7 FK506 binding protein 7
FOXK1 forkhead box K1
FOXK2 forkhead box K2
HCFC1 host cell factor C1
HCFC2 host cell factor C2
HMGB1 high mobility group box 1
HMGN1 high mobility group nucleosome binding domain 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRF2BPL interferon regulatory factor 2 binding protein-like
IRF8 interferon regulatory factor 8
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRDM1 PR domain containing 1, with ZNF domain
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
STAT1 signal transducer and activator of transcription 1, 91kDa
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
UBC ubiquitin C