| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | interferon regulatory factor 5|This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010] (NCBI Entrez Gene Database, 3663) |
| External Link | https://ncbi.nlm.nih.gov/gene/3663 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IRF5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WDR7 | WD repeat domain 7 | 0.0160337 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.0159027 |
| APOD | apolipoprotein D | 0.0158354 |
| MAP7 | microtubule-associated protein 7 | 0.0139941 |
| MMP1 | matrix metallopeptidase 1 | 0.0139388 |
| PMP22 | peripheral myelin protein 22 | 0.0138924 |
| TGM2 | transglutaminase 2 | 0.0137823 |
| ASPN | asporin | 0.0137478 |
| DSP | desmoplakin | 0.0131234 |
| CD9 | CD9 molecule | 0.0129211 |
| NVL | nuclear VCP-like | 0.0124864 |
| VEGFA | vascular endothelial growth factor A | 0.0121143 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.0120231 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0119888 |
| RAPSN | receptor-associated protein of the synapse | 0.0119218 |
| BCHE | butyrylcholinesterase | 0.0117708 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.0116749 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.011403 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0112738 |
| TPSAB1 | tryptase alpha/beta 1 | 0.0109835 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.0108476 |
| FASN | fatty acid synthase | 0.0108367 |
| PTN | pleiotrophin | 0.0107821 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0107221 |
| LMNA | lamin A/C | 0.0106988 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.0105316 |
| NNMT | nicotinamide N-methyltransferase | 0.0105196 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0104843 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0104638 |
| STK26 | serine/threonine protein kinase 26 | 0.0104287 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.0103544 |
| KIAA0930 | KIAA0930 | 0.0103173 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0102941 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.010281 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0101869 |
| DAPK1 | death-associated protein kinase 1 | 0.0101045 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0100505 |
| EMP3 | epithelial membrane protein 3 | 0.00988133 |
| HOPX | HOP homeobox | 0.00978155 |
| PLD3 | phospholipase D family, member 3 | 0.00974441 |
| CD81 | CD81 molecule | 0.00968767 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00967292 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00967198 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00966763 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00956728 |
| CD14 | CD14 molecule | 0.00952893 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00952329 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00951585 |
| POSTN | periostin, osteoblast specific factor | 0.00946524 |
| RRAGA | Ras-related GTP binding A | 0.00936371 |
| TSPAN4 | tetraspanin 4 | 0.00935444 |
| RIN2 | Ras and Rab interactor 2 | 0.0093457 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0093161 |
| TGFB3 | transforming growth factor, beta 3 | 0.0092643 |
| TNS3 | tensin 3 | 0.00925812 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00923375 |
| CP | ceruloplasmin (ferroxidase) | 0.00922905 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00901822 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00901174 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00900221 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00893522 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.00889434 |
| NOTCH1 | notch 1 | 0.00886934 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00875707 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0087449 |
| CD163 | CD163 molecule | 0.00874186 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00873682 |
| KIAA0125 | KIAA0125 | 0.00873369 |
| COL3A1 | collagen, type III, alpha 1 | 0.00873158 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00872787 |
| MICALL2 | MICAL-like 2 | 0.00872648 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00869103 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00869073 |
| NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha | 0.00868312 |
| SDC3 | syndecan 3 | 0.00866792 |
| FBLN2 | fibulin 2 | 0.00865876 |
| LAMB2 | laminin, beta 2 (laminin S) | 0.00863538 |
| TYMS | thymidylate synthetase | 0.00857513 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.00850165 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.0084817 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00839819 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00838578 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00838308 |
| TNK2 | tyrosine kinase, non-receptor, 2 | 0.0083006 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 0.00827492 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00826583 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00823766 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.00822297 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00814398 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00812352 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00811467 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00809524 |
| YBX3 | Y box binding protein 3 | 0.0080925 |
| CTSD | cathepsin D | 0.00807262 |
| REXO2 | RNA exonuclease 2 | 0.00804736 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00798252 |
| MTA1 | metastasis associated 1 | 0.00797503 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00796427 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00795303 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00793249 |
| CD320 | CD320 molecule | 0.0079203 |
| C6 | complement component 6 | 0.00789079 |
| SFTPB | surfactant protein B | 0.00788408 |
| ELN | elastin | 0.00786027 |
| HMGB3 | high mobility group box 3 | 0.00785508 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.00780305 |
| TCF4 | transcription factor 4 | 0.00778916 |
| KRT14 | keratin 14, type I | 0.00771711 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00770903 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00770032 |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.00768167 |
| CRY1 | cryptochrome circadian clock 1 | 0.00766815 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.0076289 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00761621 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00761067 |
| FN1 | fibronectin 1 | 0.00761033 |
| PCNA | proliferating cell nuclear antigen | 0.00760327 |
| PLEC | plectin | 0.00756964 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.00754983 |
| SYNM | synemin, intermediate filament protein | 0.00751823 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00751642 |
| MLPH | melanophilin | 0.00750572 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.0074888 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00748592 |
| IPO13 | importin 13 | 0.00748213 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.00747209 |
| REEP1 | receptor accessory protein 1 | 0.00745172 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00745094 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00744623 |
| TTC38 | tetratricopeptide repeat domain 38 | 0.007427 |
| STAB1 | stabilin 1 | 0.00742699 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0074102 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00740959 |
| PMF1 | polyamine-modulated factor 1 | 0.00739734 |
| GUSB | glucuronidase, beta | 0.00739534 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00737751 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00737167 |
| SFN | stratifin | 0.0073379 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00733398 |
| PAEP | progestagen-associated endometrial protein | 0.00731094 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00730489 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00730009 |
| STK25 | serine/threonine kinase 25 | 0.00729776 |
| SFTPA2 | surfactant protein A2 | 0.00728411 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.00727129 |
| CTSK | cathepsin K | 0.00726387 |
| TES | testin LIM domain protein | 0.00724834 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00723375 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0072224 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00722101 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.007199 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.00715306 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00714308 |
| SETBP1 | SET binding protein 1 | 0.0071285 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0071263 |
| MELK | maternal embryonic leucine zipper kinase | 0.00711664 |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 0.00707982 |
| MCOLN1 | mucolipin 1 | 0.00707461 |
| ITGA7 | integrin, alpha 7 | 0.00706221 |
| CMTR1 | cap methyltransferase 1 | 0.00705939 |
| GRAMD4 | GRAM domain containing 4 | 0.00704218 |
| PRDX4 | peroxiredoxin 4 | 0.00702123 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00701457 |
| AGRN | agrin | 0.00701258 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00700084 |
| TNC | tenascin C | 0.00700066 |
| CLDN4 | claudin 4 | 0.00698846 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00698191 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00696208 |
| GLA | galactosidase, alpha | 0.00694628 |
| PXDN | peroxidasin | 0.00694613 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00694558 |
| TRRAP | transformation/transcription domain-associated protein | 0.00694508 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | 0.00694445 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 | 0.00692916 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00692492 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) | 0.00692254 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00690214 |
| PLCH1 | phospholipase C, eta 1 | 0.00688812 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.00687772 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00687491 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00686072 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.00685596 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00684666 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 0.00682747 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00682298 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.00680857 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | 0.00680766 |
| COLEC12 | collectin sub-family member 12 | 0.00679331 |
| KEAP1 | kelch-like ECH-associated protein 1 | 0.00679163 |
| DMPK | dystrophia myotonica-protein kinase | 0.00677907 |
| NUBP2 | nucleotide binding protein 2 | 0.00677725 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.00677414 |
| FLOT1 | flotillin 1 | 0.00676824 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00674716 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00673937 |
| MCM7 | minichromosome maintenance complex component 7 | 0.00673915 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.00672558 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.0067094 |
| AK1 | adenylate kinase 1 | 0.00670421 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00669975 |
| MYO6 | myosin VI | 0.00669911 |
| TSPAN12 | tetraspanin 12 | 0.00669473 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | 0.00669174 |
| EHD2 | EH-domain containing 2 | 0.00668701 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.00666859 |
| KLC1 | kinesin light chain 1 | 0.00666813 |
| PON1 | paraoxonase 1 | 0.00665827 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00665511 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00665393 |
| CENPB | centromere protein B, 80kDa | 0.00664735 |
| ITGB5 | integrin, beta 5 | 0.00663901 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00663052 |
| NOTCH2NL | notch 2 N-terminal like | 0.00662872 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | 0.00660244 |
| GAL | galanin/GMAP prepropeptide | 0.00659859 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.00659768 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00658809 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00658285 |
| KIFC3 | kinesin family member C3 | 0.00657842 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00657704 |
| PCLAF | PCNA clamp associated factor | 0.00656842 |
| RGS5 | regulator of G-protein signaling 5 | 0.00656642 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00655763 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.00655422 |
| KIF5B | kinesin family member 5B | 0.00655309 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00654594 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.00654164 |
| RBPMS | RNA binding protein with multiple splicing | 0.00652605 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 0.00651976 |
| CYP2D7 | cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) | 0.00651872 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0065004 |
| TCTA | T-cell leukemia translocation altered | 0.00648992 |
| PXN | paxillin | 0.00648798 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00648591 |
| E4F1 | E4F transcription factor 1 | 0.00648523 |
| MEST | mesoderm specific transcript | 0.00646368 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00645726 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00645656 |
| CYTL1 | cytokine-like 1 | 0.00643783 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | 0.00643044 |
| FEN1 | flap structure-specific endonuclease 1 | 0.00641576 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.00641372 |
| TBCD | tubulin folding cofactor D | 0.00641031 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) | 0.00639201 |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.00638464 |
| PERP | PERP, TP53 apoptosis effector | 0.00638212 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.00637077 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.00636879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAL | mal, T-cell differentiation protein | -0.0196189 |
| ANXA3 | annexin A3 | -0.0184903 |
| ADD3 | adducin 3 (gamma) | -0.0182346 |
| S100P | S100 calcium binding protein P | -0.0173232 |
| CA2 | carbonic anhydrase II | -0.0170795 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0168162 |
| MT1F | metallothionein 1F | -0.0160168 |
| LYZ | lysozyme | -0.0159134 |
| LY75 | lymphocyte antigen 75 | -0.0159015 |
| CPE | carboxypeptidase E | -0.0146699 |
| HBB | hemoglobin, beta | -0.0146456 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0144068 |
| KIF5C | kinesin family member 5C | -0.0141877 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0138741 |
| AK4 | adenylate kinase 4 | -0.0133151 |
| CSTA | cystatin A (stefin A) | -0.013083 |
| ANXA1 | annexin A1 | -0.0129722 |
| CANX | calnexin | -0.0126156 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0125431 |
| SST | somatostatin | -0.0124923 |
| FOLR1 | folate receptor 1 (adult) | -0.012298 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.0122887 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0122175 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0121248 |
| MT1H | metallothionein 1H | -0.0120679 |
| MT1E | metallothionein 1E | -0.0120253 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.011787 |
| SELL | selectin L | -0.0116686 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0116676 |
| CALB1 | calbindin 1, 28kDa | -0.0115676 |
| MT1HL1 | metallothionein 1H-like 1 | -0.0115266 |
| MT1G | metallothionein 1G | -0.0114161 |
| GCH1 | GTP cyclohydrolase 1 | -0.0113585 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0113575 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.0113042 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0112053 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.0111554 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0111115 |
| GPC3 | glypican 3 | -0.0111002 |
| EAPP | E2F-associated phosphoprotein | -0.0109874 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.0109488 |
| CCNG1 | cyclin G1 | -0.0108489 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0107766 |
| CD200 | CD200 molecule | -0.0107639 |
| TFF1 | trefoil factor 1 | -0.0107454 |
| MPO | myeloperoxidase | -0.0107261 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.0106846 |
| CFI | complement factor I | -0.0105677 |
| LTF | lactotransferrin | -0.01056 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0105471 |
| S100A12 | S100 calcium binding protein A12 | -0.0104587 |
| DAXX | death-domain associated protein | -0.0103878 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.010385 |
| SET | SET nuclear proto-oncogene | -0.010384 |
| GUCY2C | guanylate cyclase 2C | -0.0102947 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.0102104 |
| RNASET2 | ribonuclease T2 | -0.0101569 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0101447 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0101116 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.0100563 |
| GPM6B | glycoprotein M6B | -0.0100469 |
| IL6ST | interleukin 6 signal transducer | -0.0100224 |
| DEFB1 | defensin, beta 1 | -0.00999069 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00989781 |
| CDC42 | cell division cycle 42 | -0.00983808 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00980187 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00978539 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00977829 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00973348 |
| NRN1 | neuritin 1 | -0.00971922 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0096832 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00964712 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00960802 |
| LCN2 | lipocalin 2 | -0.00960763 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00958639 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | -0.00954707 |
| EVI2A | ecotropic viral integration site 2A | -0.0094831 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00943733 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00942748 |
| SPRR3 | small proline-rich protein 3 | -0.0094094 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00940745 |
| DAZAP2 | DAZ associated protein 2 | -0.0093873 |
| PLPBP | pyridoxal phosphate binding protein | -0.00935099 |
| CNTN1 | contactin 1 | -0.00935058 |
| ZNF652 | zinc finger protein 652 | -0.00931247 |
| CNN2 | calponin 2 | -0.0093109 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00929783 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00928273 |
| CDCA4 | cell division cycle associated 4 | -0.00927537 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00926199 |
| CTSS | cathepsin S | -0.00926057 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.0092521 |
| ELANE | elastase, neutrophil expressed | -0.00923568 |
| TPM4 | tropomyosin 4 | -0.00923031 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00919813 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00919601 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -0.00912754 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -0.00910788 |
| ERP44 | endoplasmic reticulum protein 44 | -0.0090276 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00902253 |
| DUOX2 | dual oxidase 2 | -0.00901712 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00900012 |
| TSPYL5 | TSPY-like 5 | -0.00899429 |
| OLFM4 | olfactomedin 4 | -0.00892822 |
| MT2A | metallothionein 2A | -0.00891653 |
| PRPF4 | pre-mRNA processing factor 4 | -0.00890194 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00889797 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00886311 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00886171 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00885076 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.00885027 |
| EXOC5 | exocyst complex component 5 | -0.00882348 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00880978 |
| FGF13 | fibroblast growth factor 13 | -0.00880963 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00880892 |
| FHL1 | four and a half LIM domains 1 | -0.00880766 |
| ZNF430 | zinc finger protein 430 | -0.00880153 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00877603 |
| MYO1C | myosin IC | -0.00871203 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00868985 |
| CFD | complement factor D (adipsin) | -0.008657 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00865382 |
| FZD6 | frizzled class receptor 6 | -0.00864602 |
| TSPAN8 | tetraspanin 8 | -0.00861152 |
| RGS10 | regulator of G-protein signaling 10 | -0.00860004 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00859813 |
| SP140L | SP140 nuclear body protein-like | -0.00855291 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00855023 |
| IL2RG | interleukin 2 receptor, gamma | -0.00853909 |
| DOK5 | docking protein 5 | -0.00853129 |
| TPD52L1 | tumor protein D52-like 1 | -0.00850298 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00849301 |
| MAT2B | methionine adenosyltransferase II, beta | -0.00845644 |
| TXNIP | thioredoxin interacting protein | -0.00842444 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00840607 |
| SCG5 | secretogranin V | -0.00839601 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00834409 |
| BEX1 | brain expressed, X-linked 1 | -0.00831222 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00828219 |
| BTG3 | BTG family, member 3 | -0.00822796 |
| CADM1 | cell adhesion molecule 1 | -0.00820788 |
| TSPAN31 | tetraspanin 31 | -0.00818557 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00817991 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00817057 |
| TOX | thymocyte selection-associated high mobility group box | -0.00815477 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.00814256 |
| NEBL | nebulette | -0.00811988 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | -0.00809299 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00808221 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -0.00807625 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -0.00806741 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00805103 |
| KRT19 | keratin 19, type I | -0.00804313 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00804271 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.00802828 |
| FAM198B | family with sequence similarity 198, member B | -0.00801936 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.00801053 |
| YIPF5 | Yip1 domain family, member 5 | -0.00799965 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00797962 |
| CLIC3 | chloride intracellular channel 3 | -0.00797297 |
| WIF1 | WNT inhibitory factor 1 | -0.00795341 |
| TCF21 | transcription factor 21 | -0.00790669 |
| CHEK2 | checkpoint kinase 2 | -0.00790533 |
| PRKCQ | protein kinase C, theta | -0.00789543 |
| KRCC1 | lysine-rich coiled-coil 1 | -0.00788892 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00787646 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00785894 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.00784695 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -0.00784135 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00783899 |
| BEX4 | brain expressed, X-linked 4 | -0.00782738 |
| C5ORF30 | chromosome 5 open reading frame 30 | -0.0078227 |
| LY96 | lymphocyte antigen 96 | -0.00782227 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00781187 |
| ADI1 | acireductone dioxygenase 1 | -0.00780817 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00780435 |
| MT1X | metallothionein 1X | -0.00778801 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00777085 |
| USP46 | ubiquitin specific peptidase 46 | -0.00774981 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00773408 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00770164 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.00770013 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00769248 |
| AZIN1 | antizyme inhibitor 1 | -0.00768831 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00767432 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -0.00764379 |
| MMD | monocyte to macrophage differentiation-associated | -0.00764256 |
| PCP4 | Purkinje cell protein 4 | -0.00764181 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.0076391 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.00762069 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.00761504 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00758794 |
| ZNF140 | zinc finger protein 140 | -0.00757549 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00756724 |
| XIC | X chromosome inactivation center | -0.00756596 |
| CLEC2D | C-type lectin domain family 2, member D | -0.00756383 |
| KLK10 | kallikrein-related peptidase 10 | -0.00755877 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00755523 |
| FHIT | fragile histidine triad | -0.00755464 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00754004 |
| DIAPH2 | diaphanous-related formin 2 | -0.00753748 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00752531 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00748319 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00748146 |
| MGAM | maltase-glucoamylase | -0.00747653 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00747608 |
| MATR3 | matrin 3 | -0.00747293 |
| DCK | deoxycytidine kinase | -0.0074582 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | -0.00745717 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | -0.00745378 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00740419 |
| PPID | peptidylprolyl isomerase D | -0.00740165 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00739894 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00736983 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00733585 |
| ZFAND1 | zinc finger, AN1-type domain 1 | -0.00733482 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.00733314 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00733224 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00732508 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00732439 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00732257 |
| NMU | neuromedin U | -0.00731583 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.00729389 |
| UMOD | uromodulin | -0.00729173 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.00728661 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00728405 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00727318 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00726569 |
| ZNF165 | zinc finger protein 165 | -0.00725031 |
| MDFIC | MyoD family inhibitor domain containing | -0.00724828 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0072465 |
| UNC45A | unc-45 homolog A (C. elegans) | -0.00724485 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.00724297 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00723083 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | -0.00723042 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.0072227 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.00721293 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.0072125 |
| MRS2 | MRS2 magnesium transporter | -0.00720973 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.00720581 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.00718198 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00716991 |
| RNF167 | ring finger protein 167 | -0.00716803 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00714747 |
| ABHD10 | abhydrolase domain containing 10 | -0.0071474 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00714631 |
| NCOA4 | nuclear receptor coactivator 4 | -0.00713815 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | -0.00713682 |
| CD27 | CD27 molecule | -0.00713056 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.00711563 |
