IRF5 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description interferon regulatory factor 5|This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010] (NCBI Entrez Gene Database, 3663)
External Link http://www.ncbi.nlm.nih.gov/gene/3663
Similar Terms
Downloads & Tools

Genes

37 interacting proteins for IRF5 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ALPI alkaline phosphatase, intestinal
BNC2 basonuclin 2
CEP152 centrosomal protein 152kDa
CHUK conserved helix-loop-helix ubiquitous kinase
COPS2 COP9 signalosome subunit 2
COPS3 COP9 signalosome subunit 3
COPS4 COP9 signalosome subunit 4
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COPS7B COP9 signalosome subunit 7B
COPS8 COP9 signalosome subunit 8
CREBBP CREB binding protein
EP300 E1A binding protein p300
GPS1 G protein pathway suppressor 1
GRB2 growth factor receptor-bound protein 2
GTPBP1 GTP binding protein 1
GTPBP2 GTP binding protein 2
HDAC1 histone deacetylase 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IRF3 interferon regulatory factor 3
IRF6 interferon regulatory factor 6
IRF8 interferon regulatory factor 8
KAT2B K(lysine) acetyltransferase 2B
MAVS mitochondrial antiviral signaling protein
MYD88 myeloid differentiation primary response 88
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
RGS3 regulator of G-protein signaling 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIN3A SIN3 transcription regulator family member A
TBK1 TANK-binding kinase 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM15 tripartite motif containing 15
UBC ubiquitin C
XPO1 exportin 1