| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | interferon regulatory factor 7|IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3665) |
| External Link | https://ncbi.nlm.nih.gov/gene/3665 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IRF7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FABP4 | fatty acid binding protein 4, adipocyte | 0.016648 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0165932 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0143001 |
| MAGEA3 | melanoma antigen family A3 | 0.0114793 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0111845 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0105618 |
| BEX1 | brain expressed, X-linked 1 | 0.0101734 |
| TFF1 | trefoil factor 1 | 0.0100478 |
| HOXC6 | homeobox C6 | 0.00998599 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00978119 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00971256 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00916484 |
| KRT20 | keratin 20, type I | 0.00904018 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00902759 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00888295 |
| CLCA4 | chloride channel accessory 4 | 0.00874158 |
| FOXG1 | forkhead box G1 | 0.00861609 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0083791 |
| NRN1 | neuritin 1 | 0.00836189 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00817956 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00815745 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00791563 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00791167 |
| TMEM204 | transmembrane protein 204 | 0.00784628 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00772211 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00768772 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00768068 |
| FERMT1 | fermitin family member 1 | 0.00762789 |
| FABP1 | fatty acid binding protein 1, liver | 0.00750473 |
| LY75 | lymphocyte antigen 75 | 0.00747788 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00734939 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00732041 |
| XIC | X chromosome inactivation center | 0.00723871 |
| HOXB7 | homeobox B7 | 0.00720305 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00718952 |
| MAGEA12 | melanoma antigen family A12 | 0.00713683 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | 0.0071223 |
| FCGBP | Fc fragment of IgG binding protein | 0.00711466 |
| TP63 | tumor protein p63 | 0.00708927 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00703065 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00700943 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0069763 |
| ADM | adrenomedullin | 0.00689029 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00688523 |
| S100A10 | S100 calcium binding protein A10 | 0.0068741 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00685861 |
| GCH1 | GTP cyclohydrolase 1 | 0.00685294 |
| ATP10B | ATPase, class V, type 10B | 0.00684853 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00673329 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.00671888 |
| WIF1 | WNT inhibitory factor 1 | 0.00670809 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.00669767 |
| MEN1 | multiple endocrine neoplasia I | 0.00663738 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 0.00662416 |
| SNX11 | sorting nexin 11 | 0.0066096 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00660049 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0065842 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00654473 |
| ANOS1 | anosmin 1 | 0.00654051 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00649041 |
| JAG1 | jagged 1 | 0.00646184 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00646031 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00642482 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00640834 |
| CD1B | CD1b molecule | 0.00639506 |
| DENND1B | DENN/MADD domain containing 1B | 0.00638561 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00635174 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.00633633 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.0063187 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00630618 |
| DMD | dystrophin | 0.006284 |
| HDAC1 | histone deacetylase 1 | 0.00627675 |
| DSG3 | desmoglein 3 | 0.00627357 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00626931 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00622992 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00622219 |
| POSTN | periostin, osteoblast specific factor | 0.00621998 |
| PRAME | preferentially expressed antigen in melanoma | 0.00621941 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00620925 |
| AMZ2 | archaelysin family metallopeptidase 2 | 0.0061998 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00619344 |
| SFTPA2 | surfactant protein A2 | 0.00617203 |
| GPC3 | glypican 3 | 0.00614831 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00614078 |
| CD1E | CD1e molecule | 0.0061047 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00608327 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0060803 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00605632 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.00604585 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.0060418 |
| EDNRB | endothelin receptor type B | 0.00602403 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00602208 |
| MSX1 | msh homeobox 1 | 0.00602105 |
| PLPBP | pyridoxal phosphate binding protein | 0.00601718 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00600818 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.00596656 |
| TSPAN8 | tetraspanin 8 | 0.00595404 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.00592611 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.0059158 |
| RBBP7 | retinoblastoma binding protein 7 | 0.00591551 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00591206 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00590655 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00590328 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00589726 |
| MAGEA4 | melanoma antigen family A4 | 0.0058913 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 0.00586268 |
| CD1A | CD1a molecule | 0.00585959 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0058404 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00582738 |
| AGR2 | anterior gradient 2 | 0.00579884 |
| VIL1 | villin 1 | 0.00579096 |
| CCNB1 | cyclin B1 | 0.00578477 |
| ITGA6 | integrin, alpha 6 | 0.00578224 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00577803 |
| LYZ | lysozyme | 0.00576719 |
| FABP7 | fatty acid binding protein 7, brain | 0.00575613 |
| PRDX2 | peroxiredoxin 2 | 0.00573817 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00573808 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00572203 |
| PTCH1 | patched 1 | 0.00571968 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 | 0.00569682 |
| CST1 | cystatin SN | 0.00569079 |
| TMEM14A | transmembrane protein 14A | 0.00568412 |
| EPS8L3 | EPS8-like 3 | 0.00567968 |
| CHGB | chromogranin B | 0.00566773 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00564262 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00559729 |
| CD96 | CD96 molecule | 0.00558545 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00558243 |
| S100B | S100 calcium binding protein B | 0.0055795 |
| MRPS33 | mitochondrial ribosomal protein S33 | 0.00557329 |
| FAM198B | family with sequence similarity 198, member B | 0.00556735 |
| CREBL2 | cAMP responsive element binding protein-like 2 | 0.00556135 |
| PRRX1 | paired related homeobox 1 | 0.00555198 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00554289 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00553947 |
| SI | sucrase-isomaltase (alpha-glucosidase) | 0.00552878 |
| PPAP2A | phosphatidic acid phosphatase type 2A | 0.00552694 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00550943 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | 0.00547717 |
| SMYD2 | SET and MYND domain containing 2 | 0.00545427 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00545187 |
| ADORA2B | adenosine A2b receptor | 0.00543562 |
| NDRG1 | N-myc downstream regulated 1 | 0.00542301 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00542171 |
| MMP12 | matrix metallopeptidase 12 | 0.00540773 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00538733 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00538349 |
| ATP9A | ATPase, class II, type 9A | 0.00537138 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0053583 |
| IL1R2 | interleukin 1 receptor, type II | 0.00533309 |
| RHOA | ras homolog family member A | 0.00532697 |
| FAM162A | family with sequence similarity 162, member A | 0.00529628 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00528335 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00526989 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00523841 |
| TRIM14 | tripartite motif containing 14 | 0.00522338 |
| TCTA | T-cell leukemia translocation altered | 0.00522272 |
| GUCY2C | guanylate cyclase 2C | 0.00521012 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00519894 |
| CDC42 | cell division cycle 42 | 0.00517929 |
| RAB29 | RAB29, member RAS oncogene family | 0.00517768 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00517541 |
| ACOT13 | acyl-CoA thioesterase 13 | 0.00516592 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00516131 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00515965 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00515012 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00514951 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00512938 |
| HEPH | hephaestin | 0.00511612 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00511597 |
| EXOC5 | exocyst complex component 5 | 0.00511584 |
| GMPR2 | guanosine monophosphate reductase 2 | 0.00510638 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 0.00508825 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0050768 |
| SLC35A5 | solute carrier family 35, member A5 | 0.0050687 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.00505255 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00504979 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00504802 |
| TMEM100 | transmembrane protein 100 | 0.00504208 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.00500939 |
| TFF2 | trefoil factor 2 | 0.00500289 |
| DSC2 | desmocollin 2 | 0.00499807 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00499396 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 0.00494289 |
| PRSS21 | protease, serine, 21 (testisin) | 0.00493251 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00492536 |
| ITK | IL2-inducible T-cell kinase | 0.00492404 |
| FAM169A | family with sequence similarity 169, member A | 0.00492266 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | 0.00492216 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00491627 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00491549 |
| SPRR1B | small proline-rich protein 1B | 0.00491261 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.00491242 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00490686 |
| CTSE | cathepsin E | 0.00490405 |
| EZR | ezrin | 0.00490405 |
| MSH2 | mutS homolog 2 | 0.0049023 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 | 0.0048975 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.0048939 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00487737 |
| TOB1 | transducer of ERBB2, 1 | 0.00487027 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00485677 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.00485259 |
| LPXN | leupaxin | 0.00484763 |
| CLIC5 | chloride intracellular channel 5 | 0.00484125 |
| NUP85 | nucleoporin 85kDa | 0.00483438 |
| CBX1 | chromobox homolog 1 | 0.00481326 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00481022 |
| CA4 | carbonic anhydrase IV | 0.00479109 |
| ZNF426 | zinc finger protein 426 | 0.00478455 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00478293 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00476352 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0047538 |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) | 0.00475377 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00474662 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00472489 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | 0.00472303 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00470087 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.00469566 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00469381 |
| RPL36 | ribosomal protein L36 | 0.00469374 |
| TOX3 | TOX high mobility group box family member 3 | 0.00469112 |
| YIPF5 | Yip1 domain family, member 5 | 0.00468784 |
| FZD5 | frizzled class receptor 5 | 0.0046859 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.00468215 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00468008 |
| DSP | desmoplakin | 0.00466998 |
| IL27RA | interleukin 27 receptor, alpha | 0.00466975 |
| CHEK2 | checkpoint kinase 2 | 0.00466765 |
| RASA4 | RAS p21 protein activator 4 | 0.00466535 |
| KRT81 | keratin 81, type II | 0.00466441 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00465774 |
| TSC2 | tuberous sclerosis 2 | 0.00465456 |
| DCTN4 | dynactin 4 (p62) | 0.00465136 |
| FLNB | filamin B, beta | 0.00463327 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00463273 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00461161 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00460406 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00460227 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00458467 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00458294 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00458063 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 | 0.00458044 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00457624 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.00456174 |
| ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 | 0.00455768 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.00454913 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00454671 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0325725 |
| LCN2 | lipocalin 2 | -0.0184855 |
| WASHC4 | WASH complex subunit 4 | -0.0159858 |
| DEFB1 | defensin, beta 1 | -0.0136761 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0135573 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0130999 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.012189 |
| CFB | complement factor B | -0.0121162 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0120635 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0118815 |
| MGLL | monoglyceride lipase | -0.011751 |
| CLU | clusterin | -0.0117216 |
| PLBD1 | phospholipase B domain containing 1 | -0.0116436 |
| LTF | lactotransferrin | -0.0114675 |
| MMP7 | matrix metallopeptidase 7 | -0.0113024 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0112087 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0111132 |
| RNF167 | ring finger protein 167 | -0.0109612 |
| PLK2 | polo-like kinase 2 | -0.0102635 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00995026 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00989778 |
| PCDH9 | protocadherin 9 | -0.00967648 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00910706 |
| S100A9 | S100 calcium binding protein A9 | -0.00908328 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00892805 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00881282 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00874219 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00873953 |
| STK26 | serine/threonine protein kinase 26 | -0.00871091 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.0086329 |
| S100A8 | S100 calcium binding protein A8 | -0.00861134 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | -0.00858682 |
| G0S2 | G0/G1 switch 2 | -0.00858232 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00854754 |
| MX1 | MX dynamin-like GTPase 1 | -0.00853578 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00845961 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00838193 |
| BIN1 | bridging integrator 1 | -0.00830347 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00828708 |
| EMP3 | epithelial membrane protein 3 | -0.0081632 |
| IRF7 | interferon regulatory factor 7 | -0.00812801 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00792145 |
| ARG1 | arginase 1 | -0.00780676 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00778954 |
| TGFB3 | transforming growth factor, beta 3 | -0.00773023 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00772216 |
| ZIC1 | Zic family member 1 | -0.00763222 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00762319 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00761562 |
| TSPYL5 | TSPY-like 5 | -0.00759896 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0075872 |
| SCARA3 | scavenger receptor class A, member 3 | -0.00757822 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00755879 |
| IPO13 | importin 13 | -0.00754265 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00752849 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00750336 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00748373 |
| STK3 | serine/threonine kinase 3 | -0.00738874 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00738324 |
| NPY | neuropeptide Y | -0.00734503 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00733367 |
| FRMD4B | FERM domain containing 4B | -0.00732441 |
| TEX30 | testis expressed 30 | -0.00731067 |
| FJX1 | four jointed box 1 (Drosophila) | -0.00728981 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00728831 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0072563 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0072284 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00713159 |
| PLXNB2 | plexin B2 | -0.0071187 |
| TGM2 | transglutaminase 2 | -0.00710902 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00709264 |
| IFI44L | interferon-induced protein 44-like | -0.00706382 |
| SC5D | sterol-C5-desaturase | -0.00705872 |
| BLNK | B-cell linker | -0.00699811 |
| KRT7 | keratin 7, type II | -0.00699603 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00695391 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -0.00692594 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | -0.00692117 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00691333 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00690343 |
| YBX3 | Y box binding protein 3 | -0.00688598 |
| KRT23 | keratin 23, type I | -0.00683722 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00682549 |
| MB | myoglobin | -0.0068034 |
| ASRGL1 | asparaginase like 1 | -0.00674224 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00672557 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00671894 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | -0.0067107 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.00670961 |
| HIP1R | huntingtin interacting protein 1 related | -0.00670039 |
| AMOTL2 | angiomotin like 2 | -0.00668262 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00666931 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00664057 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00660896 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00659798 |
| OLFM4 | olfactomedin 4 | -0.00658492 |
| TUBA4A | tubulin, alpha 4a | -0.00657711 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00656728 |
| SCG5 | secretogranin V | -0.00655933 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00654297 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00652961 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00649404 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0064711 |
| HP | haptoglobin | -0.00644483 |
| NPEPL1 | aminopeptidase-like 1 | -0.0064228 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene | -0.00640281 |
| TSPAN4 | tetraspanin 4 | -0.0063792 |
| AIF1 | allograft inflammatory factor 1 | -0.00636452 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00636146 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00631208 |
| RRAGD | Ras-related GTP binding D | -0.00629328 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00627705 |
| SDS | serine dehydratase | -0.00627689 |
| CP | ceruloplasmin (ferroxidase) | -0.00627434 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00626735 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.00622103 |
| PFKM | phosphofructokinase, muscle | -0.00621161 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00619137 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00617299 |
| C2 | complement component 2 | -0.00615109 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00611 |
| TYMP | thymidine phosphorylase | -0.00606839 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00601439 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00601198 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00597992 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00597826 |
| ORM1 | orosomucoid 1 | -0.00595393 |
| COL5A1 | collagen, type V, alpha 1 | -0.00595069 |
| STK38 | serine/threonine kinase 38 | -0.00594604 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00593569 |
| KYNU | kynureninase | -0.00590115 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00589625 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00588802 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00586164 |
| NMU | neuromedin U | -0.00584556 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00584119 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00582006 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.0058157 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.00581305 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | -0.0057864 |
| CD37 | CD37 molecule | -0.00578227 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | -0.00577885 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00577087 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00577081 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | -0.00574087 |
| NKX3-1 | NK3 homeobox 1 | -0.00571625 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00570783 |
| BPI | bactericidal/permeability-increasing protein | -0.00568684 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00567891 |
| CFH | complement factor H | -0.00564172 |
| CCNA1 | cyclin A1 | -0.00562145 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00561656 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | -0.00560632 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00559677 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00558009 |
| OTUD4 | OTU deubiquitinase 4 | -0.00556648 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00554434 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00553857 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00552897 |
| MMP9 | matrix metallopeptidase 9 | -0.00552807 |
| LAT2 | linker for activation of T cells family, member 2 | -0.00552532 |
| PROS1 | protein S (alpha) | -0.00551978 |
| CLDN10 | claudin 10 | -0.00551134 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00549103 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.00548335 |
| TCF3 | transcription factor 3 | -0.00546831 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00545641 |
| RHOD | ras homolog family member D | -0.00545103 |
| CTPS1 | CTP synthase 1 | -0.00543501 |
| APOD | apolipoprotein D | -0.00543307 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00542487 |
| VPREB1 | pre-B lymphocyte 1 | -0.00542257 |
| IRX5 | iroquois homeobox 5 | -0.0054206 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00541786 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | -0.00540509 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00539962 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00539482 |
| RTN2 | reticulon 2 | -0.00538917 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00538741 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00537357 |
| LIN7A | lin-7 homolog A (C. elegans) | -0.00536975 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00536716 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00536551 |
| RND3 | Rho family GTPase 3 | -0.00535898 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.00535568 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00535256 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00535169 |
| ECM1 | extracellular matrix protein 1 | -0.0053479 |
| C1R | complement component 1, r subcomponent | -0.00534512 |
| CRY1 | cryptochrome circadian clock 1 | -0.00533755 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00533539 |
| TMEM131L | transmembrane 131 like | -0.00533204 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00532647 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00530175 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | -0.00528919 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00528903 |
| LST1 | leukocyte specific transcript 1 | -0.00528159 |
| MICB | MHC class I polypeptide-related sequence B | -0.00527814 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -0.00526552 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00526317 |
| SIK3 | SIK family kinase 3 | -0.00525158 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.00524865 |
| CD81 | CD81 molecule | -0.00524281 |
| HLX | H2.0-like homeobox | -0.0052421 |
| EGR1 | early growth response 1 | -0.0052265 |
| GLRX2 | glutaredoxin 2 | -0.00522629 |
| SMAD7 | SMAD family member 7 | -0.00521102 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.0052075 |
| RAI2 | retinoic acid induced 2 | -0.00520634 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0052035 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00519114 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00518748 |
| WT1 | Wilms tumor 1 | -0.00518492 |
| RYBP | RING1 and YY1 binding protein | -0.00516416 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.00516355 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00516028 |
| FST | follistatin | -0.00514028 |
| CENPU | centromere protein U | -0.00513219 |
| DUSP5 | dual specificity phosphatase 5 | -0.00513177 |
| FERMT2 | fermitin family member 2 | -0.00512356 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.00512149 |
| CKM | creatine kinase, muscle | -0.00510963 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00510538 |
| ADIRF | adipogenesis regulatory factor | -0.00509846 |
| MT1E | metallothionein 1E | -0.00507136 |
| HTRA1 | HtrA serine peptidase 1 | -0.00507123 |
| AREG | amphiregulin | -0.00504867 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00504576 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00502278 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.00502176 |
| GMPR | guanosine monophosphate reductase | -0.00501256 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00501222 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.00500444 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00500045 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00499343 |
| HHEX | hematopoietically expressed homeobox | -0.00498571 |
| FLNC | filamin C, gamma | -0.00497726 |
| ATG4B | autophagy related 4B, cysteine peptidase | -0.00497238 |
| CLGN | calmegin | -0.00496844 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00495636 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00494003 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00493372 |
| CLDN1 | claudin 1 | -0.00492503 |
| PALMD | palmdelphin | -0.0049202 |
| EHD2 | EH-domain containing 2 | -0.00491951 |
| EFHD1 | EF-hand domain family, member D1 | -0.00491609 |
| ZNF91 | zinc finger protein 91 | -0.00490694 |
| CRYAB | crystallin, alpha B | -0.00488976 |
| C3AR1 | complement component 3a receptor 1 | -0.00488407 |
| CD14 | CD14 molecule | -0.00487007 |