IRF7 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description interferon regulatory factor 7|IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3665)
External Link http://www.ncbi.nlm.nih.gov/gene/3665
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109 interacting proteins for IRF7 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AIP aryl hydrocarbon receptor interacting protein
ALK anaplastic lymphoma receptor tyrosine kinase
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGAP9 Rho GTPase activating protein 9
BMPR1B bone morphogenetic protein receptor, type IB
CCDC47 coiled-coil domain containing 47
CD14 CD14 molecule
CDK13 cyclin-dependent kinase 13
CENPF centromere protein F, 350/400kDa
CHUK conserved helix-loop-helix ubiquitous kinase
CREBBP CREB binding protein
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEAF1 DEAF1 transcription factor
DGKZ diacylglycerol kinase, zeta
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
EIF4B eukaryotic translation initiation factor 4B
EP300 E1A binding protein p300
EPHA1 EPH receptor A1
EPHB3 EPH receptor B3
FADD Fas (TNFRSF6)-associated via death domain
FN3K fructosamine 3 kinase
GAK cyclin G associated kinase
GCLM glutamate-cysteine ligase, modifier subunit
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
IFIH1 interferon induced with helicase C domain 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INSL6 insulin-like 6
INSR insulin receptor
IQSEC1 IQ motif and Sec7 domain 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK4 interleukin-1 receptor-associated kinase 4
IRF3 interferon regulatory factor 3
IRS4 insulin receptor substrate 4
ITK IL2-inducible T-cell kinase
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KRT18 keratin 18, type I
KRT74 keratin 74, type II
LMNB1 lamin B1
LTN1 listerin E3 ubiquitin protein ligase 1
LY96 lymphocyte antigen 96
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARK1 MAP/microtubule affinity-regulating kinase 1
MAVS mitochondrial antiviral signaling protein
MEP1B meprin A, beta
MTIF2 mitochondrial translational initiation factor 2
MYD88 myeloid differentiation primary response 88
MYLK myosin light chain kinase
NMI N-myc (and STAT) interactor
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PALD1 phosphatase domain containing, paladin 1
PDLIM5 PDZ and LIM domain 5
PDX1 pancreatic and duodenal homeobox 1
PIAS4 protein inhibitor of activated STAT, 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB2 phospholipase C, beta 2
PLCG1 phospholipase C, gamma 1
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRK protein tyrosine phosphatase, receptor type, K
RAB35 RAB35, member RAS oncogene family
RAD17 RAD17 homolog (S. pombe)
RNF135 ring finger protein 135
SH3GL3 SH3-domain GRB2-like 3
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMC6 structural maintenance of chromosomes 6
SOCS1 suppressor of cytokine signaling 1
SOCS5 suppressor of cytokine signaling 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TGFBR1 transforming growth factor, beta receptor 1
TICAM1 toll-like receptor adaptor molecule 1
TICAM2 toll-like receptor adaptor molecule 2
TLK2 tousled-like kinase 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
TRIM25 tripartite motif containing 25
TRIM28 tripartite motif containing 28
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMT61B tRNA methyltransferase 61B
UBASH3A ubiquitin associated and SH3 domain containing A
UBC ubiquitin C
UBE2B ubiquitin-conjugating enzyme E2B
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1