| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ISG15 ubiquitin-like modifier|The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012] (NCBI Entrez Gene Database, 9636) |
| External Link | https://ncbi.nlm.nih.gov/gene/9636 |
| Similar Terms | |
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499 genes differentially expressed following the ISG15 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.0278462 |
| NELL2 | NEL-like 2 (chicken) | 0.0158409 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.0153221 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0139199 |
| SFTPA2 | surfactant protein A2 | 0.013899 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0130717 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.0121628 |
| RAB25 | RAB25, member RAS oncogene family | 0.0118033 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0117312 |
| PRKCB | protein kinase C, beta | 0.011671 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0114785 |
| KIF20A | kinesin family member 20A | 0.0114269 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0113388 |
| IL2RG | interleukin 2 receptor, gamma | 0.0112516 |
| SFTPC | surfactant protein C | 0.0106383 |
| CD2 | CD2 molecule | 0.0105374 |
| SFTPB | surfactant protein B | 0.0103759 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.0103484 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0102814 |
| CDCA4 | cell division cycle associated 4 | 0.0102385 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0100484 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00989111 |
| GLOD4 | glyoxalase domain containing 4 | 0.00986048 |
| PRKCA | protein kinase C, alpha | 0.00969034 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00962626 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00961856 |
| CIT | citron rho-interacting serine/threonine kinase | 0.00960838 |
| PCP4 | Purkinje cell protein 4 | 0.00944117 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00934385 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00920533 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00919761 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00918881 |
| CRLF1 | cytokine receptor-like factor 1 | 0.0091528 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00908199 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00895733 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00892719 |
| COG7 | component of oligomeric golgi complex 7 | 0.00891141 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00879733 |
| WIF1 | WNT inhibitory factor 1 | 0.0087788 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00875615 |
| FASN | fatty acid synthase | 0.00874671 |
| CCNA2 | cyclin A2 | 0.00867171 |
| CHKB | choline kinase beta | 0.00867169 |
| CCNB2 | cyclin B2 | 0.00858754 |
| SSBP3 | single stranded DNA binding protein 3 | 0.00857973 |
| RAPSN | receptor-associated protein of the synapse | 0.00857463 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00856493 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00851299 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 0.0084181 |
| SDC2 | syndecan 2 | 0.00841576 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00841128 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00835122 |
| ENO1 | enolase 1, (alpha) | 0.0082887 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00827919 |
| LMNB2 | lamin B2 | 0.0082583 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00825427 |
| CDC45 | cell division cycle 45 | 0.00820861 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.0081973 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00819508 |
| PCGF2 | polycomb group ring finger 2 | 0.00815129 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | 0.00814681 |
| KIF11 | kinesin family member 11 | 0.00800178 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00799614 |
| BCL7B | B-cell CLL/lymphoma 7B | 0.00795163 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.00793978 |
| AUTS2 | autism susceptibility candidate 2 | 0.0078801 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00787803 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00787439 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00787032 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00785965 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00785674 |
| MCOLN1 | mucolipin 1 | 0.00783461 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.0077971 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00779184 |
| RANBP1 | RAN binding protein 1 | 0.0077843 |
| RBMX | RNA binding motif protein, X-linked | 0.00775945 |
| LMNB1 | lamin B1 | 0.00775314 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00773707 |
| CCNF | cyclin F | 0.00773211 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.00772753 |
| TRAF4 | TNF receptor-associated factor 4 | 0.00771456 |
| LYZ | lysozyme | 0.00770831 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.0076964 |
| EPCAM | epithelial cell adhesion molecule | 0.00769588 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00767754 |
| HOXC10 | homeobox C10 | 0.00766713 |
| KIF15 | kinesin family member 15 | 0.00763145 |
| MAOA | monoamine oxidase A | 0.00762905 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00761207 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00759677 |
| CD1E | CD1e molecule | 0.00757898 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00757658 |
| LBR | lamin B receptor | 0.00756929 |
| RRM1 | ribonucleotide reductase M1 | 0.00754774 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00750457 |
| TRMT5 | tRNA methyltransferase 5 | 0.00747655 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.00743899 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.00742877 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00742043 |
| HOXC6 | homeobox C6 | 0.00741086 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.00733096 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00732362 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00731446 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.0072692 |
| GRK6 | G protein-coupled receptor kinase 6 | 0.00725676 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00724207 |
| INSIG1 | insulin induced gene 1 | 0.00723518 |
| DEK | DEK proto-oncogene | 0.00722468 |
| SLC2A4RG | SLC2A4 regulator | 0.00721722 |
| CENPF | centromere protein F, 350/400kDa | 0.00720056 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.00719718 |
| ACACA | acetyl-CoA carboxylase alpha | 0.00719695 |
| KIAA0226L | KIAA0226-like | 0.00719122 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00716376 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00714052 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00714012 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00713336 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.00712587 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.00711998 |
| VWA1 | von Willebrand factor A domain containing 1 | 0.00710593 |
| IRX5 | iroquois homeobox 5 | 0.00710174 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00710135 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 | 0.00708336 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00708331 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00704949 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.00703955 |
| SELL | selectin L | 0.00703952 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00702854 |
| CD1B | CD1b molecule | 0.0070105 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00701001 |
| NTS | neurotensin | 0.00700895 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00700367 |
| LPXN | leupaxin | 0.00699547 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00698045 |
| THYN1 | thymocyte nuclear protein 1 | 0.00697842 |
| CBX5 | chromobox homolog 5 | 0.00697255 |
| EPN2 | epsin 2 | 0.00697088 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00695117 |
| SALL2 | spalt-like transcription factor 2 | 0.00694707 |
| SVIL | supervillin | 0.00693993 |
| CD1A | CD1a molecule | 0.00693381 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | 0.00693201 |
| DCK | deoxycytidine kinase | 0.00689021 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00688381 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00687564 |
| NREP | neuronal regeneration related protein | 0.0068726 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00687162 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.00686598 |
| NOTCH3 | notch 3 | 0.00684922 |
| TLK1 | tousled-like kinase 1 | 0.00684849 |
| BARD1 | BRCA1 associated RING domain 1 | 0.00684743 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00684367 |
| CABIN1 | calcineurin binding protein 1 | 0.00683993 |
| THAP12 | THAP domain containing 12 | 0.00682717 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.00681856 |
| SEPTIN9 | septin 9 | 0.00681651 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00680875 |
| ACP6 | acid phosphatase 6, lysophosphatidic | 0.00679515 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.00678975 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00678808 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.00678065 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00673431 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00672949 |
| MMP12 | matrix metallopeptidase 12 | 0.00672789 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00672443 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00671609 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00669489 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00668894 |
| CEP55 | centrosomal protein 55kDa | 0.00668224 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 0.00667968 |
| CD200 | CD200 molecule | 0.00666577 |
| BSPRY | B-box and SPRY domain containing | 0.00666533 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.006656 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00665265 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00661778 |
| TSPYL5 | TSPY-like 5 | 0.00661726 |
| TNC | tenascin C | 0.00660232 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.00659413 |
| OIP5 | Opa interacting protein 5 | 0.0065799 |
| PIMREG | PICALM interacting mitotic regulator | 0.00656407 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00655972 |
| WWOX | WW domain containing oxidoreductase | 0.00655958 |
| CUL4B | cullin 4B | 0.00655221 |
| IQCE | IQ motif containing E | 0.00654886 |
| ADK | adenosine kinase | 0.00654485 |
| SIRT3 | sirtuin 3 | 0.00654401 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00653443 |
| NDRG3 | NDRG family member 3 | 0.0065283 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00651604 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.00651233 |
| UNC119B | unc-119 homolog B (C. elegans) | 0.00650389 |
| KIFC1 | kinesin family member C1 | 0.00650364 |
| HMGB2 | high mobility group box 2 | 0.00649375 |
| SHTN1 | shootin 1 | 0.00649121 |
| CCNB1 | cyclin B1 | 0.00647997 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00647871 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.00647322 |
| ADRA2A | adrenoceptor alpha 2A | 0.00647165 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00647005 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 0.00645589 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00642686 |
| ZNF266 | zinc finger protein 266 | 0.00642107 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00641469 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00640707 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00639142 |
| GPR183 | G protein-coupled receptor 183 | 0.006363 |
| H2AX | H2A.X variant histone | 0.00635945 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00635203 |
| FOXM1 | forkhead box M1 | 0.00635076 |
| CD1C | CD1c molecule | 0.00634642 |
| DHFR | dihydrofolate reductase | 0.00634436 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00633839 |
| CA9 | carbonic anhydrase IX | 0.00633671 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00633366 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | 0.00633181 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00633139 |
| FCMR | Fc fragment of IgM receptor | 0.00632052 |
| ESRP2 | epithelial splicing regulatory protein 2 | 0.00631675 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.00631268 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.00629867 |
| TMC5 | transmembrane channel-like 5 | 0.00629801 |
| PRUNE1 | prune exopolyphosphatase 1 | 0.00628784 |
| POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 | 0.00627758 |
| FANCL | Fanconi anemia, complementation group L | 0.00627377 |
| KIF1B | kinesin family member 1B | 0.00626536 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00624203 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00623745 |
| GRAMD4 | GRAM domain containing 4 | 0.00622588 |
| PFKL | phosphofructokinase, liver | 0.00622366 |
| LTA4H | leukotriene A4 hydrolase | 0.0062084 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | 0.00620631 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00619685 |
| NIPSNAP2 | nipsnap homolog 2 | 0.00619399 |
| CDK1 | cyclin-dependent kinase 1 | 0.00618734 |
| CBR3 | carbonyl reductase 3 | 0.00618397 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.00618341 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0061773 |
| FLOT2 | flotillin 2 | 0.00617015 |
| TYRO3 | TYRO3 protein tyrosine kinase | 0.00616657 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00615904 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00614422 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | 0.00614251 |
| PKP4 | plakophilin 4 | 0.00613454 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00613395 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00612952 |
| RETREG1 | reticulophagy regulator 1 | 0.00612576 |
| NPAT | nuclear protein, ataxia-telangiectasia locus | 0.00612547 |
| CES1 | carboxylesterase 1 | 0.00611826 |
| ATXN10 | ataxin 10 | 0.0061057 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00610546 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FABP4 | fatty acid binding protein 4, adipocyte | -0.025254 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0231385 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0199095 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0177806 |
| ADIRF | adipogenesis regulatory factor | -0.0172214 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0170351 |
| CLU | clusterin | -0.0166431 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0150238 |
| PDGFD | platelet derived growth factor D | -0.0148067 |
| LRRC17 | leucine rich repeat containing 17 | -0.0147629 |
| C3 | complement component 3 | -0.0147483 |
| KRT23 | keratin 23, type I | -0.0144397 |
| ASS1 | argininosuccinate synthase 1 | -0.0141074 |
| CA2 | carbonic anhydrase II | -0.0141007 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.0140428 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0139265 |
| IFI44L | interferon-induced protein 44-like | -0.0138462 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0138193 |
| HIST1H2BD | histone cluster 1, H2bd | -0.0136999 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0136804 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.0136141 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0136099 |
| MFAP5 | microfibrillar associated protein 5 | -0.0136076 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.0133967 |
| HMOX1 | heme oxygenase 1 | -0.0132943 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0132731 |
| RTN2 | reticulon 2 | -0.0131589 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0130839 |
| WDR7 | WD repeat domain 7 | -0.0130485 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.0128723 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.0127242 |
| MT1X | metallothionein 1X | -0.0124888 |
| MMP1 | matrix metallopeptidase 1 | -0.0124886 |
| TRIM22 | tripartite motif containing 22 | -0.0123084 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0122694 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0122305 |
| ASPN | asporin | -0.0121827 |
| DCN | decorin | -0.0121635 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0121128 |
| ACKR3 | atypical chemokine receptor 3 | -0.0120363 |
| SNAI2 | snail family zinc finger 2 | -0.012022 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0120015 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0119991 |
| TNS3 | tensin 3 | -0.0119981 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.0119965 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.011986 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0119832 |
| MT1E | metallothionein 1E | -0.0119378 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0119232 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0119231 |
| RND3 | Rho family GTPase 3 | -0.0118894 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0118318 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0117786 |
| NNMT | nicotinamide N-methyltransferase | -0.0117703 |
| MIR22HG | MIR22 host gene | -0.0116794 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0116332 |
| AREG | amphiregulin | -0.0115956 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0115197 |
| CD163 | CD163 molecule | -0.0115044 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0114928 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0114046 |
| H1-2 | H1.2 linker histone, cluster member | -0.0113856 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0113811 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.011299 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0112911 |
| L1CAM | L1 cell adhesion molecule | -0.0112615 |
| KRT14 | keratin 14, type I | -0.0112287 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0111542 |
| MAGEA3 | melanoma antigen family A3 | -0.0111415 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0111317 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0110779 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0110582 |
| RGS5 | regulator of G-protein signaling 5 | -0.010982 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0109489 |
| MVP | major vault protein | -0.0109223 |
| LXN | latexin | -0.0108773 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.010779 |
| EGR1 | early growth response 1 | -0.0107696 |
| NRCAM | neuronal cell adhesion molecule | -0.0107243 |
| CD93 | CD93 molecule | -0.0106905 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0105784 |
| FN1 | fibronectin 1 | -0.0104653 |
| MYBPC1 | myosin binding protein C, slow type | -0.0104612 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0104558 |
| PSCA | prostate stem cell antigen | -0.0104504 |
| CFD | complement factor D (adipsin) | -0.0104497 |
| SGCE | sarcoglycan, epsilon | -0.010351 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0102845 |
| CST1 | cystatin SN | -0.0102792 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0102476 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0101752 |
| LUM | lumican | -0.0101613 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.0101106 |
| GPX1 | glutathione peroxidase 1 | -0.0100878 |
| FHL2 | four and a half LIM domains 2 | -0.0100439 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00996371 |
| BTG2 | BTG family, member 2 | -0.00994624 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0098531 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00976447 |
| KLHL41 | kelch-like family member 41 | -0.00966655 |
| C1S | complement component 1, s subcomponent | -0.00965902 |
| TAGLN | transgelin | -0.00965597 |
| S100A8 | S100 calcium binding protein A8 | -0.00964725 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00955644 |
| PLK2 | polo-like kinase 2 | -0.00954137 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00953186 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00951543 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00950297 |
| KRT17 | keratin 17, type I | -0.00949483 |
| STC2 | stanniocalcin 2 | -0.00947742 |
| PLAU | plasminogen activator, urokinase | -0.00946551 |
| PRSS23 | protease, serine, 23 | -0.00946312 |
| CFB | complement factor B | -0.00946185 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.00943817 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00938062 |
| TAC1 | tachykinin, precursor 1 | -0.00936804 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00936669 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00933021 |
| MECOM | MDS1 and EVI1 complex locus | -0.00927157 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00926933 |
| CRYAB | crystallin, alpha B | -0.00926509 |
| MXRA5 | matrix-remodelling associated 5 | -0.00925487 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00921308 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00919606 |
| MT1G | metallothionein 1G | -0.00919001 |
| COL3A1 | collagen, type III, alpha 1 | -0.00915418 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00911333 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00911319 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00908976 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00908202 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00907741 |
| ZNF91 | zinc finger protein 91 | -0.00906056 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00905412 |
| TMEM176B | transmembrane protein 176B | -0.00903889 |
| MOSPD1 | motile sperm domain containing 1 | -0.00901364 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00899291 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00897956 |
| MITF | microphthalmia-associated transcription factor | -0.00897299 |
| DUSP7 | dual specificity phosphatase 7 | -0.00897029 |
| MT1H | metallothionein 1H | -0.00896419 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -0.0089457 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.00892048 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00891774 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.00890417 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.00888936 |
| EGR3 | early growth response 3 | -0.00887033 |
| TNNC1 | troponin C type 1 (slow) | -0.00883389 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00880961 |
| STOM | stomatin | -0.00880489 |
| THBS2 | thrombospondin 2 | -0.00879087 |
| E2F2 | E2F transcription factor 2 | -0.00878201 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00877246 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.008757 |
| EHD3 | EH-domain containing 3 | -0.00875064 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00871474 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00870391 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00870134 |
| LEPROT | leptin receptor overlapping transcript | -0.00868331 |
| COL5A2 | collagen, type V, alpha 2 | -0.00867497 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0086693 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00863312 |
| CFH | complement factor H | -0.00862421 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | -0.00861646 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00860499 |
| SRPX | sushi-repeat containing protein, X-linked | -0.0085388 |
| IRF7 | interferon regulatory factor 7 | -0.00852606 |
| CD14 | CD14 molecule | -0.0085036 |
| FSTL1 | follistatin-like 1 | -0.00848561 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00847589 |
| S100A9 | S100 calcium binding protein A9 | -0.00846477 |
| CLIC5 | chloride intracellular channel 5 | -0.00844816 |
| S100A2 | S100 calcium binding protein A2 | -0.00844595 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00844026 |
| CPM | carboxypeptidase M | -0.00843899 |
| INHBB | inhibin, beta B | -0.00842372 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00840965 |
| MYOT | myotilin | -0.00840419 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00838638 |
| FMO1 | flavin containing monooxygenase 1 | -0.00838623 |
| INHBE | inhibin, beta E | -0.008386 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00837561 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00837211 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00836208 |
| RRAD | Ras-related associated with diabetes | -0.00834491 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00833559 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00832022 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00827793 |
| RGS13 | regulator of G-protein signaling 13 | -0.0082753 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00826427 |
| ZFHX4 | zinc finger homeobox 4 | -0.00825037 |
| PALMD | palmdelphin | -0.00824905 |
| OLFML2A | olfactomedin-like 2A | -0.00824378 |
| RGS16 | regulator of G-protein signaling 16 | -0.00823267 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00822633 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00822568 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00822184 |
| PROCR | protein C receptor, endothelial | -0.00815236 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00814108 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00812513 |
| IL6 | interleukin 6 | -0.00809119 |
| CCNG2 | cyclin G2 | -0.00807284 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00806851 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00805396 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00804832 |
| MYOZ2 | myozenin 2 | -0.00804696 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00802525 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00801636 |
| DUSP6 | dual specificity phosphatase 6 | -0.00798828 |
| CTSL | cathepsin L | -0.00798087 |
| MB | myoglobin | -0.00797762 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | -0.00796782 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.0079558 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00793944 |
| ELOB | elongin B | -0.00789437 |
| IL18 | interleukin 18 | -0.00788467 |
| ASPA | aspartoacylase | -0.00788287 |
| TPBG | trophoblast glycoprotein | -0.00786961 |
| MYOF | myoferlin | -0.0078673 |
| CP | ceruloplasmin (ferroxidase) | -0.00786516 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00785763 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0078173 |
| RET | ret proto-oncogene | -0.00780972 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00778913 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00777811 |
| FOXO1 | forkhead box O1 | -0.00776856 |
| GAS1 | growth arrest-specific 1 | -0.00775697 |
| IER5 | immediate early response 5 | -0.00774893 |
| SPP1 | secreted phosphoprotein 1 | -0.00774518 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00774125 |
| PPL | periplakin | -0.00773845 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00769957 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00769558 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00767114 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00765847 |
| LOXL2 | lysyl oxidase-like 2 | -0.00764669 |
| PITX3 | paired-like homeodomain 3 | -0.00763308 |
| PPIF | peptidylprolyl isomerase F | -0.00763155 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00762438 |
| IL1RN | interleukin 1 receptor antagonist | -0.00761299 |
| IL32 | interleukin 32 | -0.00759904 |
| MX1 | MX dynamin-like GTPase 1 | -0.00757461 |
| HBP1 | HMG-box transcription factor 1 | -0.00756758 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00756283 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -0.00755472 |
| SLN | sarcolipin | -0.00752931 |
| PLTP | phospholipid transfer protein | -0.00752606 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.00752192 |
| RBM34 | RNA binding motif protein 34 | -0.00751408 |
| LGI1 | leucine-rich, glioma inactivated 1 | -0.00751215 |