ISG20 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description interferon stimulated exonuclease gene 20kDa| (NCBI Entrez Gene Database, 3669)
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Genes

313 genes differentially expressed following the ISG20 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NPPA natriuretic peptide A 2.63417
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 2.63417
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.63417
SFRP5 secreted frizzled-related protein 5 2.63417
EXTL1 exostosin-like glycosyltransferase 1 2.63417
VSX2 visual system homeobox 2 2.63417
THBD thrombomodulin 2.63417
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.63417
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 2.63417
WNT5A wingless-type MMTV integration site family, member 5A 2.63417
KRT222 keratin 222, type II 2.63417
HAPLN2 hyaluronan and proteoglycan link protein 2 2.63417
KRTAP13-4 keratin associated protein 13-4 2.63417
ASCL3 achaete-scute family bHLH transcription factor 3 2.63417
LRRTM1 leucine rich repeat transmembrane neuronal 1 2.63417
VTN vitronectin 2.63417
SLC51B solute carrier family 51, beta subunit 2.63417
KLHL34 kelch-like family member 34 2.63417
FAM151A family with sequence similarity 151, member A 2.63417
RORC RAR-related orphan receptor C 2.63417
CFAP65 cilia and flagella associated protein 65 2.63417
CLDN16 claudin 16 2.63417
OCSTAMP osteoclast stimulatory transmembrane protein 2.63417
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.63417
GUCA1C guanylate cyclase activator 1C 2.61431
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B 2.61431
HBA2 hemoglobin, alpha 2 2.61431
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.61431
CD5 CD5 molecule 2.61431
FABP9 fatty acid binding protein 9, testis 2.61431
CLEC12B C-type lectin domain family 12, member B 2.61431
NCBP2L nuclear cap binding protein subunit 2-like 2.61431
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.61431
SF3B3 splicing factor 3b, subunit 3, 130kDa 2.61431
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.61431
CLEC12A C-type lectin domain family 12, member A 2.61431
FAM180B family with sequence similarity 180, member B 2.61431
XCL1 chemokine (C motif) ligand 1 2.61431
ASB12 ankyrin repeat and SOCS box containing 12 2.61431
REN renin 2.61431
SHCBP1L SHC SH2-domain binding protein 1-like 2.61431
TAL2 T-cell acute lymphocytic leukemia 2 2.61431
SLC23A3 solute carrier family 23, member 3 2.61431
TNIP3 TNFAIP3 interacting protein 3 2.61431
ASMT acetylserotonin O-methyltransferase 2.61431
PTGFR prostaglandin F receptor (FP) 2.61431
SFTPB surfactant protein B 2.61431
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.61431
TYROBP TYRO protein tyrosine kinase binding protein 2.61431
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.61431
ZNF208 zinc finger protein 208 2.61431
IRX1 iroquois homeobox 1 2.61431
CD14 CD14 molecule 2.61431
CELF3 CUGBP, Elav-like family member 3 2.61431
TMEM176A transmembrane protein 176A 2.61431
CELA3A chymotrypsin-like elastase family, member 3A 2.61431
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2.61431
TM4SF1 transmembrane 4 L six family member 1 2.61431
PEAR1 platelet endothelial aggregation receptor 1 2.61431
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.61431
SLC15A5 solute carrier family 15, member 5 2.61431
LITAFD LITAF domain containing 2.61431
PDC phosducin 2.61431
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 2.61431
C1QTNF9B C1q and tumor necrosis factor related protein 9B 2.61431
OR1C1 olfactory receptor, family 1, subfamily C, member 1 2.61431
ASB4 ankyrin repeat and SOCS box containing 4 2.61431
TSPAN1 tetraspanin 1 2.61431
IMPG1 interphotoreceptor matrix proteoglycan 1 2.61431
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.61431
FGFBP1 fibroblast growth factor binding protein 1 2.61431
PKD2L1 polycystic kidney disease 2-like 1 2.61431
TNNC1 troponin C type 1 (slow) 2.61431
PNLIPRP2 pancreatic lipase-related protein 2 2.61431
CIMAP1D CIMAP1 family member D 2.61431
LINC02798 long intergenic non-protein coding RNA 2798 2.61431
H3C3 H3 clustered histone 3 2.61431
ACP4 acid phosphatase 4 2.61431
TERB1 telomere repeat binding bouquet formation protein 1 2.61431
CCDC187 coiled-coil domain containing 187 2.61431
DEPP1 DEPP autophagy regulator 1 2.61431
FYB1 FYN binding protein 1 2.61431
KY kyphoscoliosis peptidase 2.61431
SAA2 serum amyloid A2 2.61431
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.61431
CCR8 chemokine (C-C motif) receptor 8 2.61431
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 2.61431
TMIE transmembrane inner ear 2.61431
LOC124901872 uncharacterized LOC124901872 2.61431
PRB4 proline-rich protein BstNI subfamily 4 2.61431
OASL 2'-5'-oligoadenylate synthetase-like 2.61431
PCDHA6 protocadherin alpha 6 2.61431
ACOT4 acyl-CoA thioesterase 4 2.61431
ZNF436 zinc finger protein 436 2.61431
ATP13A5 ATPase type 13A5 2.61431
CCDC17 coiled-coil domain containing 17 2.61431
C4ORF17 chromosome 4 open reading frame 17 2.61431
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.61431
GJD2 gap junction protein, delta 2, 36kDa 2.61431
GJD4 gap junction protein, delta 4, 40.1kDa 2.61431
CREB3L3 cAMP responsive element binding protein 3-like 3 2.61431
GDF10 growth differentiation factor 10 2.61431
TLR4 toll-like receptor 4 2.61431
OVOL3 ovo-like zinc finger 3 2.61431
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.61431
GOLGA6L4 golgin A6 family-like 4 2.61431
C3ORF80 chromosome 3 open reading frame 80 2.61431
TBX20 T-box 20 2.61431
CPB1 carboxypeptidase B1 (tissue) 2.61431
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.61431
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.61431
CERKL ceramide kinase-like 2.61431
TESPA1 thymocyte expressed, positive selection associated 1 2.61431
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 2.61431
ANKRD65 ankyrin repeat domain 65 2.61431
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.61431
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 2.61431
APOC4 apolipoprotein C-IV 2.61431
DRD3 dopamine receptor D3 2.61431
ACCSL 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like 2.61431
C18ORF63 chromosome 18 open reading frame 63 2.61431
ACSM4 acyl-CoA synthetase medium-chain family member 4 2.61431
PRSS57 protease, serine, 57 2.61431
ERMN ermin, ERM-like protein 2.61431
TBPL2 TATA box binding protein like 2 2.61431
LRRC32 leucine rich repeat containing 32 2.61431
TTBK1 tau tubulin kinase 1 2.61431
SPHKAP SPHK1 interactor, AKAP domain containing 2.61431
FNDC1 fibronectin type III domain containing 1 2.61431
RBMXL3 RNA binding motif protein, X-linked-like 3 2.61431
WNT7A wingless-type MMTV integration site family, member 7A 2.61431
COX7B2 cytochrome c oxidase subunit VIIb2 2.61431
SIGLEC15 sialic acid binding Ig-like lectin 15 2.61431
MAGED4B melanoma antigen family D4B 2.61431
OTOP2 otopetrin 2 2.61431
CCNI2 cyclin I family, member 2 2.61431
KCTD12 potassium channel tetramerization domain containing 12 2.61431
ETV3L ets variant 3-like 2.61431
CXORF58 chromosome X open reading frame 58 2.61431
C22ORF31 chromosome 22 open reading frame 31 2.61431
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 2.61431
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.61431
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.61431
MBTD1 mbt domain containing 1 2.61431
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 2.61431
CCL17 chemokine (C-C motif) ligand 17 2.61431
SEC14L3 SEC14-like 3 (S. cerevisiae) 2.61431
CFI complement factor I 2.61431
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 2.61431
C8ORF89 chromosome 8 open reading frame 89 2.61431
KLK3 kallikrein-related peptidase 3 2.61431
UTS2B urotensin 2B 2.61431
LRRC24 leucine rich repeat containing 24 2.61431
IL2RA interleukin 2 receptor, alpha 2.61431
HMGA2 high mobility group AT-hook 2 2.61431
LRRC63 leucine rich repeat containing 63 2.61431
TPX2 TPX2, microtubule-associated 2.61431
MUC20 mucin 20, cell surface associated 2.61431
CLEC2A C-type lectin domain family 2, member A 2.61431
MMP20 matrix metallopeptidase 20 2.61431
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 2.61431
HES2 hes family bHLH transcription factor 2 2.61431
C2ORF78 chromosome 2 open reading frame 78 2.61431
KLLN killin, p53-regulated DNA replication inhibitor 2.61431
RNF133 ring finger protein 133 2.61431
BMP3 bone morphogenetic protein 3 2.61431
PRDM12 PR domain containing 12 2.61431
IL2RB interleukin 2 receptor, beta 2.61431
ICAM2 intercellular adhesion molecule 2 2.61431
DLL4 delta-like 4 (Drosophila) 2.61431
ICAM5 intercellular adhesion molecule 5, telencephalin 2.61431
POU3F2 POU class 3 homeobox 2 2.61431
CRIP2 cysteine-rich protein 2 2.61431
SLITRK1 SLIT and NTRK-like family, member 1 2.61431
C2ORF66 chromosome 2 open reading frame 66 2.61431
PXT1 peroxisomal, testis specific 1 2.61431
MT1M metallothionein 1M 2.61431
CCNO cyclin O 2.61431
ANKK1 ankyrin repeat and kinase domain containing 1 2.61431
PATE2 prostate and testis expressed 2 2.61431
C4BPA complement component 4 binding protein, alpha 2.61431
CETP cholesteryl ester transfer protein, plasma 2.61431
DSCAML1 Down syndrome cell adhesion molecule like 1 2.60981
AGBL3 ATP/GTP binding protein-like 3 2.53172
CDK17 cyclin-dependent kinase 17 2.49894
WAS Wiskott-Aldrich syndrome 2.49852
MXRA5 matrix-remodelling associated 5 2.49852
SBK2 SH3 domain binding kinase family, member 2 2.49852
BTBD17 BTB (POZ) domain containing 17 2.48898
PYGO1 pygopus family PHD finger 1 2.39668
LRRC8D leucine rich repeat containing 8 family, member D 2.35536
TBC1D28 TBC1 domain family, member 28 2.33737
DLG2 discs, large homolog 2 (Drosophila) 2.33294
SAMD7 sterile alpha motif domain containing 7 2.33026
MRPL23 mitochondrial ribosomal protein L23 2.30081
BTC betacellulin 2.29284
RPL30 ribosomal protein L30 2.27927
NUP58 nucleoporin 58 2.23955
PLLP plasmolipin 2.21014
POLRMT polymerase (RNA) mitochondrial (DNA directed) 2.20021
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.1868
CEP68 centrosomal protein 68kDa 2.17526
KAT6A K(lysine) acetyltransferase 6A 2.16926
DOCK2 dedicator of cytokinesis 2 2.16926
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 2.14812
ERI3 ERI1 exoribonuclease family member 3 2.14105
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.12944
DGKK diacylglycerol kinase, kappa 2.11573
RNF144B ring finger protein 144B 2.09578
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.05675
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 2.01916
PTPRN protein tyrosine phosphatase, receptor type, N 2.01916
RTL8C retrotransposon Gag like 8C 2.01854
COL25A1 collagen, type XXV, alpha 1 2.01032
POM121 POM121 transmembrane nucleoporin 2.00195

decreased expression

Symbol Name Standardized Value
RBMX RNA binding motif protein, X-linked -2.63417
CORIN corin, serine peptidase -2.63417
LCN2 lipocalin 2 -2.61611
ATG9B autophagy related 9B -2.61611
AGTR1 angiotensin II receptor, type 1 -2.61431
SPON2 spondin 2, extracellular matrix protein -2.61431
COL2A1 collagen, type II, alpha 1 -2.61431
TTLL6 tubulin tyrosine ligase-like family member 6 -2.61431
KIAA0232 KIAA0232 -2.61431
MED9 mediator complex subunit 9 -2.61431
FAM107A family with sequence similarity 107, member A -2.61431
IRF2-DT IRF2 divergent transcript -2.61431
GUK1 guanylate kinase 1 -2.61431
FOLR1 folate receptor 1 (adult) -2.61431
PDE7B phosphodiesterase 7B -2.61431
PAX3 paired box 3 -2.61431
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy -2.61431
OLFM3 olfactomedin 3 -2.61431
ASPA aspartoacylase -2.61431
MSMP microseminoprotein, prostate associated -2.61431
C11ORF87 chromosome 11 open reading frame 87 -2.61431
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 -2.61431
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.61431
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae) -2.61431
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.61431
KLK4 kallikrein-related peptidase 4 -2.61431
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.61431
SVOP SV2 related protein homolog (rat) -2.61431
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 -2.61431
FLACC1 flagellum associated containing coiled-coil domains 1 -2.61431
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -2.61431
ADAP1 ArfGAP with dual PH domains 1 -2.61431
ALKAL1 ALK and LTK ligand 1 -2.61431
OPTN optineurin -2.61431
GBX1 gastrulation brain homeobox 1 -2.61431
NTF4 neurotrophin 4 -2.61431
KRI1 KRI1 homolog (S. cerevisiae) -2.61431
PIWIL1 piwi-like RNA-mediated gene silencing 1 -2.61431
PTGDS prostaglandin D2 synthase 21kDa (brain) -2.61431
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -2.61431
RAG1 recombination activating gene 1 -2.61431
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -2.60738
RHOU ras homolog family member U -2.59524
JADE3 jade family PHD finger 3 -2.56014
ZSCAN21 zinc finger and SCAN domain containing 21 -2.55105
L1TD1 LINE-1 type transposase domain containing 1 -2.50256
A4GALT alpha 1,4-galactosyltransferase -2.50048
GRHL3 grainyhead-like 3 (Drosophila) -2.50048
DMPK dystrophia myotonica-protein kinase -2.49894
DNM2 dynamin 2 -2.40917
ZDHHC12 zinc finger, DHHC-type containing 12 -2.39761
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 -2.33737
EIF4A3 eukaryotic translation initiation factor 4A3 -2.32672
CLTB clathrin, light chain B -2.31771
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -2.31771
MIER1 mesoderm induction early response 1, transcriptional regulator -2.30081
OTOGL otogelin-like -2.29284
ZNF296 zinc finger protein 296 -2.29284
ADAT1 adenosine deaminase, tRNA-specific 1 -2.26942
DEPDC4 DEP domain containing 4 -2.26822
IL17RC interleukin 17 receptor C -2.26212
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -2.25989
PANK2 pantothenate kinase 2 -2.25653
SPRYD3 SPRY domain containing 3 -2.21256
MYLIP myosin regulatory light chain interacting protein -2.19771
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -2.1868
NOXO1 NADPH oxidase organizer 1 -2.16926
GYPE glycophorin E (MNS blood group) -2.16926
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 -2.16926
WDR25 WD repeat domain 25 -2.16093
CDK12 cyclin-dependent kinase 12 -2.1561
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -2.14105
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -2.11954
SNRK SNF related kinase -2.11504
COX7C cytochrome c oxidase subunit VIIc -2.11484
BTN3A1 butyrophilin, subfamily 3, member A1 -2.10313
RIPOR1 RHO family interacting cell polarization regulator 1 -2.10296
CNTN5 contactin 5 -2.10261
SNIP1 Smad nuclear interacting protein 1 -2.08928
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.08629
TMEM165 transmembrane protein 165 -2.07983
CLCN3 chloride channel, voltage-sensitive 3 -2.07933
MAST1 microtubule associated serine/threonine kinase 1 -2.0734
TPM2 tropomyosin 2 (beta) -2.06884
BTBD8 BTB (POZ) domain containing 8 -2.06281
ZNF621 zinc finger protein 621 -2.05675
GRID1 glutamate receptor, ionotropic, delta 1 -2.05379
PPP4R2 protein phosphatase 4, regulatory subunit 2 -2.05258
NRN1L neuritin 1-like -2.03485
ANKRD10 ankyrin repeat domain 10 -2.03231
OTUD5 OTU deubiquitinase 5 -2.0294
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -2.02382
ADAMTSL1 ADAMTS-like 1 -2.01933
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -2.01854
EIF3A eukaryotic translation initiation factor 3, subunit A -2.01854
MBD2 methyl-CpG binding domain protein 2 -2.01854
BBS4 Bardet-Biedl syndrome 4 -2.00658
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit -2.00658