ISOX Gene Set
Genes
26 genes differentially expressed following the ISOX small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PLA2G15
|
phospholipase A2, group XV
|
4.07032
|
|
GLRX
|
glutaredoxin (thioltransferase)
|
3.75424
|
|
NME7
|
NME/NM23 family member 7
|
3.63039
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.36019
|
|
GCDH
|
glutaryl-CoA dehydrogenase
|
3.35788
|
|
CCND3
|
cyclin D3
|
3.3357
|
|
CD22
|
CD22 molecule
|
3.33332
|
|
STXBP1
|
syntaxin binding protein 1
|
3.16623
|
|
PTPN1
|
protein tyrosine phosphatase, non-receptor type 1
|
3.04647
|
|
GMCL1
|
germ cell-less, spermatogenesis associated 1
|
3.02396
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.02188
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KEAP1
|
kelch-like ECH-associated protein 1
|
-4.77821
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
-3.94355
|
|
GATAD1
|
GATA zinc finger domain containing 1
|
-3.60347
|
|
PMF1
|
polyamine-modulated factor 1
|
-3.40736
|
|
UFC1
|
ubiquitin-fold modifier conjugating enzyme 1
|
-3.32968
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.28508
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-3.22796
|
|
ATF1
|
activating transcription factor 1
|
-3.22238
|
|
RCC1L
|
RCC1 like
|
-3.16525
|
|
CCL7
|
chemokine (C-C motif) ligand 7
|
-3.13738
|
|
ZFP64
|
ZFP64 zinc finger protein
|
-3.13669
|
|
GABPB1
|
GA binding protein transcription factor, beta subunit 1
|
-3.04674
|
|
STAG1
|
stromal antigen 1
|
-3.04393
|
|
TMED1
|
transmembrane emp24 protein transport domain containing 1
|
-3.03957
|
|
TYMS
|
thymidylate synthetase
|
-3.02179
|
