| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)|This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 3673) |
| External Link | https://ncbi.nlm.nih.gov/gene/3673 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the ITGA2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | 0.0114841 |
| RNASET2 | ribonuclease T2 | 0.0108716 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0108446 |
| S100A7 | S100 calcium binding protein A7 | 0.0107712 |
| MAGEA3 | melanoma antigen family A3 | 0.0103665 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0103421 |
| S100A10 | S100 calcium binding protein A10 | 0.0102042 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0101461 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0100946 |
| MT1G | metallothionein 1G | 0.010037 |
| PROM1 | prominin 1 | 0.00996546 |
| HBB | hemoglobin, beta | 0.00976495 |
| TSPYL5 | TSPY-like 5 | 0.00973375 |
| MT1H | metallothionein 1H | 0.00971729 |
| MT2A | metallothionein 2A | 0.00960577 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00955827 |
| MPO | myeloperoxidase | 0.00935299 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00934585 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00919542 |
| MAGEA4 | melanoma antigen family A4 | 0.009146 |
| FGF13 | fibroblast growth factor 13 | 0.00910276 |
| S100P | S100 calcium binding protein P | 0.0090566 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00901063 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0089287 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00880768 |
| COL21A1 | collagen, type XXI, alpha 1 | 0.00867497 |
| MT1HL1 | metallothionein 1H-like 1 | 0.008579 |
| ELANE | elastase, neutrophil expressed | 0.00857855 |
| CA2 | carbonic anhydrase II | 0.00856628 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00853506 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00851875 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0084695 |
| CHGB | chromogranin B | 0.00846599 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00843895 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00842057 |
| ARG2 | arginase 2 | 0.00841356 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0083569 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00832701 |
| VLDLR | very low density lipoprotein receptor | 0.00830868 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00826758 |
| KRT81 | keratin 81, type II | 0.00825159 |
| CSTA | cystatin A (stefin A) | 0.00824689 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.0081538 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00809563 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00807776 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00801966 |
| ANXA3 | annexin A3 | 0.00801129 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00795128 |
| MAGEA12 | melanoma antigen family A12 | 0.0079148 |
| FHL1 | four and a half LIM domains 1 | 0.00785963 |
| DES | desmin | 0.00781451 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00777325 |
| RRAD | Ras-related associated with diabetes | 0.00771768 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00764613 |
| PERP | PERP, TP53 apoptosis effector | 0.00759444 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00759126 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.007582 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00751548 |
| LDB3 | LIM domain binding 3 | 0.00748018 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00745506 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00739876 |
| PRAME | preferentially expressed antigen in melanoma | 0.00738977 |
| CD200 | CD200 molecule | 0.007386 |
| DEFB1 | defensin, beta 1 | 0.00738278 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00737187 |
| KRT15 | keratin 15, type I | 0.00736978 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00736673 |
| COG7 | component of oligomeric golgi complex 7 | 0.00732832 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00732013 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00729429 |
| TCP1 | t-complex 1 | 0.00729088 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00723081 |
| MT1X | metallothionein 1X | 0.00721593 |
| MT1F | metallothionein 1F | 0.00719758 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00719572 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.0071755 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00717201 |
| HBD | hemoglobin, delta | 0.00711692 |
| TPD52 | tumor protein D52 | 0.00711318 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.00710579 |
| MSMB | microseminoprotein, beta- | 0.00710082 |
| RHCG | Rh family, C glycoprotein | 0.00708531 |
| SPRR1B | small proline-rich protein 1B | 0.00707479 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00705446 |
| POU4F1 | POU class 4 homeobox 1 | 0.00700617 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0069967 |
| CRNN | cornulin | 0.00698196 |
| CDC20 | cell division cycle 20 | 0.00696023 |
| RPN2 | ribophorin II | 0.00694648 |
| KRT6A | keratin 6A, type II | 0.00692398 |
| MAGEA1 | melanoma antigen family A1 | 0.00688605 |
| TPD52L1 | tumor protein D52-like 1 | 0.00687413 |
| SPRR2B | small proline-rich protein 2B | 0.00687366 |
| CRYAB | crystallin, alpha B | 0.00685332 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00681507 |
| STK32B | serine/threonine kinase 32B | 0.00679012 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00677492 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00675372 |
| HMOX1 | heme oxygenase 1 | 0.00671424 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00669624 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0066679 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00666386 |
| STOM | stomatin | 0.00666359 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00664363 |
| SALL1 | spalt-like transcription factor 1 | 0.00655826 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00653315 |
| YBX3 | Y box binding protein 3 | 0.00652239 |
| CFD | complement factor D (adipsin) | 0.00650681 |
| PLIN2 | perilipin 2 | 0.00649967 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00647717 |
| TAC1 | tachykinin, precursor 1 | 0.00645916 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00643647 |
| SYNGR3 | synaptogyrin 3 | 0.00642943 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00642842 |
| JUP | junction plakoglobin | 0.00642147 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.00638857 |
| NUCLEOLIN | nucleolin multifunctional protein | 0.00638518 |
| RET | ret proto-oncogene | 0.00638021 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00636568 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00635473 |
| ECM1 | extracellular matrix protein 1 | 0.00632926 |
| FZD5 | frizzled class receptor 5 | 0.00632455 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.0063147 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00630942 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00629271 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0062836 |
| GDF15 | growth differentiation factor 15 | 0.00628066 |
| EPN2 | epsin 2 | 0.00627913 |
| TKTL1 | transketolase-like 1 | 0.00627851 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00626174 |
| KIF2C | kinesin family member 2C | 0.00623608 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00622564 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.00621593 |
| XPO7 | exportin 7 | 0.00620794 |
| COCH | cochlin | 0.00619908 |
| ELOVL1 | ELOVL fatty acid elongase 1 | 0.00619457 |
| SPRR3 | small proline-rich protein 3 | 0.00616204 |
| SCEL | sciellin | 0.00615324 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00611535 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00610448 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00607116 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.00603208 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00599222 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00598517 |
| MALL | mal, T-cell differentiation protein-like | 0.00597114 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00596279 |
| PPL | periplakin | 0.00596014 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.00590999 |
| PCDH9 | protocadherin 9 | 0.00590573 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 0.00590435 |
| RNF167 | ring finger protein 167 | 0.00586962 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00586472 |
| CAPN6 | calpain 6 | 0.0058625 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00585884 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00585676 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00585068 |
| UXS1 | UDP-glucuronate decarboxylase 1 | 0.00584761 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.0058372 |
| DSG1 | desmoglein 1 | 0.00582406 |
| TGFA | transforming growth factor, alpha | 0.00581351 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) | 0.00578579 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.0057751 |
| MT1E | metallothionein 1E | 0.00575769 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00575244 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00573258 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00570843 |
| PLCB4 | phospholipase C, beta 4 | 0.00569995 |
| SVIL | supervillin | 0.00569367 |
| SELE | selectin E | 0.00569323 |
| JAK1 | Janus kinase 1 | 0.00567492 |
| UNC45A | unc-45 homolog A (C. elegans) | 0.00565425 |
| KLHL41 | kelch-like family member 41 | 0.00565065 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00564888 |
| FHL2 | four and a half LIM domains 2 | 0.00564733 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00564538 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00564124 |
| CAST | calpastatin | 0.00563695 |
| SMPX | small muscle protein, X-linked | 0.00562608 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00562146 |
| KRT16 | keratin 16, type I | 0.00561189 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00560159 |
| TNNC2 | troponin C type 2 (fast) | 0.00558557 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00557919 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.005558 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | 0.00553498 |
| S100A12 | S100 calcium binding protein A12 | 0.00553008 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00552412 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.00550049 |
| MYO1C | myosin IC | 0.0054795 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00547798 |
| LAMA3 | laminin, alpha 3 | 0.00547348 |
| CLIC3 | chloride intracellular channel 3 | 0.00547086 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00546712 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00545531 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00541344 |
| MVP | major vault protein | 0.00540924 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.005407 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00540137 |
| GPR17 | G protein-coupled receptor 17 | 0.00537919 |
| DEFB4A | defensin, beta 4A | 0.0053778 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.00537283 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00536814 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00536798 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00535903 |
| MCAM | melanoma cell adhesion molecule | 0.00535522 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00535226 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 0.00534586 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00532328 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00532065 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00530851 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00529962 |
| STAG3 | stromal antigen 3 | 0.0052923 |
| COQ8A | coenzyme Q8A | 0.00528167 |
| NID1 | nidogen 1 | 0.00527398 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00527311 |
| MYBPC1 | myosin binding protein C, slow type | 0.0052702 |
| INAVA | innate immunity activator | 0.00525901 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.0052542 |
| CTSA | cathepsin A | 0.00525072 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00521772 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00521639 |
| SPRR1A | small proline-rich protein 1A | 0.00520712 |
| BAG3 | BCL2-associated athanogene 3 | 0.0052008 |
| DAXX | death-domain associated protein | 0.0051982 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.00519437 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00518838 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.00517161 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00517139 |
| CNTN1 | contactin 1 | 0.0051658 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00516506 |
| IRS2 | insulin receptor substrate 2 | 0.00516484 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | 0.00516056 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00515789 |
| ITSN2 | intersectin 2 | 0.00515038 |
| ITGA6 | integrin, alpha 6 | 0.00514431 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00513979 |
| EDN3 | endothelin 3 | 0.00512703 |
| ZNF512B | zinc finger protein 512B | 0.00512163 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 0.00512123 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00511873 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00511455 |
| USP10 | ubiquitin specific peptidase 10 | 0.00509832 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00509216 |
| KRT13 | keratin 13, type I | 0.00509173 |
| CHPT1 | choline phosphotransferase 1 | 0.00509094 |
| UBAP2 | ubiquitin associated protein 2 | 0.00508872 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00508547 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.00508297 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa | 0.00507944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| WDR7 | WD repeat domain 7 | -0.0196245 |
| MMP1 | matrix metallopeptidase 1 | -0.0116705 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0112839 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0110445 |
| GSTO1 | glutathione S-transferase omega 1 | -0.0109067 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0105623 |
| FST | follistatin | -0.0100811 |
| MECOM | MDS1 and EVI1 complex locus | -0.0100043 |
| CEL | carboxyl ester lipase | -0.00998936 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00997377 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00988786 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00975068 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00965259 |
| SNAI2 | snail family zinc finger 2 | -0.00964766 |
| WBP5 | WW domain binding protein 5 | -0.00958214 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00948748 |
| RGS4 | regulator of G-protein signaling 4 | -0.0093418 |
| TMSB15A | thymosin beta 15a | -0.00926216 |
| METRN | meteorin, glial cell differentiation regulator | -0.00913148 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00891568 |
| PLAT | plasminogen activator, tissue | -0.0088239 |
| THAP12 | THAP domain containing 12 | -0.00875102 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00868488 |
| MMP9 | matrix metallopeptidase 9 | -0.00867877 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00867469 |
| CFH | complement factor H | -0.00866915 |
| CD9 | CD9 molecule | -0.00855838 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00836981 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00828664 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00822258 |
| CTSZ | cathepsin Z | -0.00809469 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00807044 |
| CD163 | CD163 molecule | -0.00805674 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00797699 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00790394 |
| FASN | fatty acid synthase | -0.00782233 |
| SMYD3 | SET and MYND domain containing 3 | -0.00780417 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00779587 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00775618 |
| CP | ceruloplasmin (ferroxidase) | -0.00761628 |
| TRIB2 | tribbles pseudokinase 2 | -0.00758326 |
| HPF1 | histone PARylation factor 1 | -0.00756603 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00747818 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00742944 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00737101 |
| IER3IP1 | immediate early response 3 interacting protein 1 | -0.00736918 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00735956 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00734916 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00729862 |
| TCF4 | transcription factor 4 | -0.00729688 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00728654 |
| THYN1 | thymocyte nuclear protein 1 | -0.00725653 |
| ELN | elastin | -0.00721742 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00719826 |
| GAS1 | growth arrest-specific 1 | -0.00716555 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00714666 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.00709919 |
| LOXL1 | lysyl oxidase-like 1 | -0.00709772 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00709301 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00708425 |
| CCNF | cyclin F | -0.00707029 |
| CDCA4 | cell division cycle associated 4 | -0.00704835 |
| TYMP | thymidine phosphorylase | -0.00701546 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00699422 |
| METTL7A | methyltransferase like 7A | -0.00695655 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N | -0.00694949 |
| APOC1 | apolipoprotein C-I | -0.00692824 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00692276 |
| CD2 | CD2 molecule | -0.0069111 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00689953 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00688996 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00682511 |
| LOX | lysyl oxidase | -0.0068101 |
| DUSP2 | dual specificity phosphatase 2 | -0.00678658 |
| TMEM126B | transmembrane protein 126B | -0.00676999 |
| FGL2 | fibrinogen-like 2 | -0.00675761 |
| LRRC15 | leucine rich repeat containing 15 | -0.00673096 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00666599 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | -0.00665276 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00662454 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00660095 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00660075 |
| DAPK1 | death-associated protein kinase 1 | -0.00656507 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00655819 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00653735 |
| CD14 | CD14 molecule | -0.00653382 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -0.00652902 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00652177 |
| DBF4 | DBF4 zinc finger | -0.00652151 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00651262 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00650949 |
| TIPRL | TOR signaling pathway regulator | -0.00649092 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00647816 |
| PIR | pirin (iron-binding nuclear protein) | -0.00643309 |
| C1R | complement component 1, r subcomponent | -0.0064249 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00640828 |
| MRPL48 | mitochondrial ribosomal protein L48 | -0.0063927 |
| TXNL1 | thioredoxin-like 1 | -0.00638001 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00633237 |
| TMEM14A | transmembrane protein 14A | -0.00630941 |
| ATP13A3 | ATPase type 13A3 | -0.00628986 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00625164 |
| AMH | anti-Mullerian hormone | -0.00624647 |
| SLA | Src-like-adaptor | -0.0062094 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00619086 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00617718 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00617071 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00616683 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00613929 |
| ASPN | asporin | -0.00611073 |
| CBX6 | chromobox homolog 6 | -0.00610599 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00609401 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00609201 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -0.00605509 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0060473 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00602623 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00601739 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00600795 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.00597907 |
| THBS1 | thrombospondin 1 | -0.00597478 |
| NREP | neuronal regeneration related protein | -0.00597355 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00596186 |
| DACH1 | dachshund family transcription factor 1 | -0.00591032 |
| PLD3 | phospholipase D family, member 3 | -0.00588959 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00588213 |
| EMILIN1 | elastin microfibril interfacer 1 | -0.00586681 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00585059 |
| LRRC17 | leucine rich repeat containing 17 | -0.00583505 |
| THY1 | Thy-1 cell surface antigen | -0.00583085 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00577882 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00577852 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.0057783 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00576983 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00575309 |
| TXLNA | taxilin alpha | -0.00573163 |
| NDP | Norrie disease (pseudoglioma) | -0.00572598 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0057124 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00569536 |
| FAM172A | family with sequence similarity 172, member A | -0.0056789 |
| ESR1 | estrogen receptor 1 | -0.00567328 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00567073 |
| KIF1B | kinesin family member 1B | -0.00565745 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00562427 |
| MRPS10 | mitochondrial ribosomal protein S10 | -0.00561135 |
| ACTL6A | actin-like 6A | -0.00560349 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.00558506 |
| TSPO | translocator protein (18kDa) | -0.00558325 |
| DCN | decorin | -0.0055811 |
| TMEM160 | transmembrane protein 160 | -0.00557985 |
| CIDEA | cell death-inducing DFFA-like effector a | -0.00556567 |
| OLFML2B | olfactomedin-like 2B | -0.00555652 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00555618 |
| GLUL | glutamate-ammonia ligase | -0.00555392 |
| CDO1 | cysteine dioxygenase type 1 | -0.00554489 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00554402 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00554033 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00552982 |
| CD48 | CD48 molecule | -0.00552846 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.00552448 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00551391 |
| SHOX2 | short stature homeobox 2 | -0.0054998 |
| MOK | MOK protein kinase | -0.00549322 |
| NNMT | nicotinamide N-methyltransferase | -0.00548589 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00548558 |
| SCG5 | secretogranin V | -0.00547358 |
| F2R | coagulation factor II (thrombin) receptor | -0.005473 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.00546228 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00545815 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.00545572 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00545324 |
| EVI2A | ecotropic viral integration site 2A | -0.00544993 |
| FPR1 | formyl peptide receptor 1 | -0.00544276 |
| CDK1 | cyclin-dependent kinase 1 | -0.00543207 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.00542939 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.0054244 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | -0.00540111 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00538998 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00538569 |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | -0.00537895 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00537777 |
| HOXB2 | homeobox B2 | -0.00537623 |
| COMP | cartilage oligomeric matrix protein | -0.0053563 |
| AHR | aryl hydrocarbon receptor | -0.0053545 |
| PLXNC1 | plexin C1 | -0.00535031 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00534635 |
| SELENOW | selenoprotein W | -0.0053427 |
| RCAN2 | regulator of calcineurin 2 | -0.00534063 |
| DDHD2 | DDHD domain containing 2 | -0.00533395 |
| LYPLA1 | lysophospholipase I | -0.00532895 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.00532344 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00532093 |
| PLS3 | plastin 3 | -0.00531555 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00531119 |
| HDAC9 | histone deacetylase 9 | -0.00531066 |
| TENM4 | teneurin transmembrane protein 4 | -0.00530348 |
| RGS10 | regulator of G-protein signaling 10 | -0.00530205 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -0.00529306 |
| TMEM164 | transmembrane protein 164 | -0.00528582 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.0052833 |
| PHGDH | phosphoglycerate dehydrogenase | -0.0052709 |
| IL7R | interleukin 7 receptor | -0.00527051 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00526879 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00525531 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00524692 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00523649 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00523379 |
| INSIG1 | insulin induced gene 1 | -0.0052325 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | -0.00522518 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | -0.00521781 |
| ECT2 | epithelial cell transforming 2 | -0.00521349 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.00520137 |
| NAV3 | neuron navigator 3 | -0.00520021 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00519794 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00519642 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.00519016 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00518399 |
| HAS2 | hyaluronan synthase 2 | -0.00518199 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00518087 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0051569 |
| TMEM106C | transmembrane protein 106C | -0.0051522 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0051469 |
| GUK1 | guanylate kinase 1 | -0.00514077 |
| C6 | complement component 6 | -0.00513403 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00513327 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.00512299 |
| MMP13 | matrix metallopeptidase 13 | -0.00511997 |
| ZW10 | zw10 kinetochore protein | -0.00511104 |
| RDX | radixin | -0.00510806 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00510634 |
| TEX2 | testis expressed 2 | -0.00509162 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | -0.00508608 |
| CTSD | cathepsin D | -0.0050785 |
| OSBPL1A | oxysterol binding protein-like 1A | -0.00506198 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00506144 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00505774 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00505667 |
| COL3A1 | collagen, type III, alpha 1 | -0.00505474 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0050532 |
| MEX3C | mex-3 RNA binding family member C | -0.00505306 |
| EMP1 | epithelial membrane protein 1 | -0.00505235 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | -0.00504122 |
| UBL3 | ubiquitin-like 3 | -0.00502625 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00502535 |
| ZFHX4 | zinc finger homeobox 4 | -0.00502444 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 | -0.00501768 |
| PRODH | proline dehydrogenase (oxidase) 1 | -0.00501647 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00499952 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -0.0049962 |
| DCK | deoxycytidine kinase | -0.00498935 |
