ITGA2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)|This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 3673)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ITGA2
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Genes

57 co-expressed genes for ITGA2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADAMTSL3 ADAMTS-like 3
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
CADM4 cell adhesion molecule 4
CD8A CD8a molecule
CDC73 cell division cycle 73
CLCN3 chloride channel, voltage-sensitive 3
COL14A1 collagen, type XIV, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
CXCL5 chemokine (C-X-C motif) ligand 5
DBT dihydrolipoamide branched chain transacylase E2
DMD dystrophin
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
EXOC4 exocyst complex component 4
EYA1 EYA transcriptional coactivator and phosphatase 1
FAM153B family with sequence similarity 153, member B
FBXL4 F-box and leucine-rich repeat protein 4
GLRA3 glycine receptor, alpha 3
GPR171 G protein-coupled receptor 171
GUCY2F guanylate cyclase 2F, retinal
HEPH hephaestin
IFNA10 interferon, alpha 10
IFNA2 interferon, alpha 2
IFNA8 interferon, alpha 8
IL7 interleukin 7
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KRT2 keratin 2, type II
KRT34 keratin 34, type I
LDB3 LIM domain binding 3
LGI1 leucine-rich, glioma inactivated 1
LOR loricrin
MAP2 microtubule-associated protein 2
NHEJ1 nonhomologous end-joining factor 1
NPFF neuropeptide FF-amide peptide precursor
NR3C2 nuclear receptor subfamily 3, group C, member 2
OPCML opioid binding protein/cell adhesion molecule-like
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PHOX2B paired-like homeobox 2b
PSG1 pregnancy specific beta-1-glycoprotein 1
PTPN20 protein tyrosine phosphatase, non-receptor type 20
PTPRB protein tyrosine phosphatase, receptor type, B
RAD51D RAD51 paralog D
RREB1 ras responsive element binding protein 1
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SPA17 sperm autoantigenic protein 17
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAC SH3 and cysteine rich domain
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TLL1 tolloid-like 1
TTTY1 testis-specific transcript, Y-linked 1 (non-protein coding)
VSTM4 V-set and transmembrane domain containing 4
ZNF132 zinc finger protein 132
ZSCAN26 zinc finger and SCAN domain containing 26