| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)|ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3674) |
| External Link | https://ncbi.nlm.nih.gov/gene/3674 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the ITGA2B gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COMP | cartilage oligomeric matrix protein | 0.0140298 |
| VCAN | versican | 0.0128573 |
| INHBA | inhibin, beta A | 0.0115676 |
| G0S2 | G0/G1 switch 2 | 0.0106486 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.0102072 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00980318 |
| ADIRF | adipogenesis regulatory factor | 0.00976344 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00929654 |
| CD9 | CD9 molecule | 0.00927155 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00920821 |
| NMU | neuromedin U | 0.00913913 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00890542 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00890361 |
| SYT1 | synaptotagmin I | 0.00887812 |
| EPHB2 | EPH receptor B2 | 0.00878156 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00874987 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.0086576 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00859434 |
| MAGEA3 | melanoma antigen family A3 | 0.00857677 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00844288 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00842043 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0084025 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00837853 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00824219 |
| GPSM2 | G-protein signaling modulator 2 | 0.00822552 |
| BICC1 | BicC family RNA binding protein 1 | 0.00820508 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00819086 |
| THBS4 | thrombospondin 4 | 0.008102 |
| LEPR | leptin receptor | 0.0078689 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00767617 |
| HOXC10 | homeobox C10 | 0.00767271 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00766786 |
| PROM1 | prominin 1 | 0.00766251 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00766235 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00754593 |
| CCNG2 | cyclin G2 | 0.00751793 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00748876 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00742806 |
| CHKB | choline kinase beta | 0.00738249 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00736699 |
| BLNK | B-cell linker | 0.00734235 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00727512 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00725642 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.00720725 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00719901 |
| MAL | mal, T-cell differentiation protein | 0.00719645 |
| IL7R | interleukin 7 receptor | 0.00719123 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00716426 |
| RAB13 | RAB13, member RAS oncogene family | 0.00714528 |
| MLF1 | myeloid leukemia factor 1 | 0.00714288 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | 0.00711137 |
| TOB1 | transducer of ERBB2, 1 | 0.007062 |
| HMGB1 | high mobility group box 1 | 0.00700671 |
| SDC2 | syndecan 2 | 0.00698701 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00698651 |
| CTSZ | cathepsin Z | 0.00696327 |
| CLU | clusterin | 0.0069434 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00693023 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0069029 |
| TYMS | thymidylate synthetase | 0.00688323 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.0067307 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00668577 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00668136 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00663753 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00660585 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00660326 |
| MX1 | MX dynamin-like GTPase 1 | 0.00657374 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00652488 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00651871 |
| CFB | complement factor B | 0.00647769 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0064576 |
| CTSS | cathepsin S | 0.00638861 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.00636534 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00633977 |
| UBXN7 | UBX domain protein 7 | 0.00632883 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00632351 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00630609 |
| NEK2 | NIMA-related kinase 2 | 0.00624677 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00623745 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0062335 |
| NINJ2 | ninjurin 2 | 0.00622915 |
| TNC | tenascin C | 0.00620086 |
| RRAGD | Ras-related GTP binding D | 0.00619382 |
| THAP9-AS1 | THAP9 antisense RNA 1 | 0.00619179 |
| NUTF2 | nuclear transport factor 2 | 0.00618976 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00618647 |
| HOXC6 | homeobox C6 | 0.00617423 |
| BRD2 | bromodomain containing 2 | 0.0061729 |
| ENOPH1 | enolase-phosphatase 1 | 0.00617203 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.00616949 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00615623 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0061413 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00611243 |
| COL10A1 | collagen, type X, alpha 1 | 0.00608326 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00607994 |
| MT1M | metallothionein 1M | 0.00604859 |
| CHRDL1 | chordin-like 1 | 0.0060309 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.00602658 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00601312 |
| METTL7A | methyltransferase like 7A | 0.00599259 |
| ATF3 | activating transcription factor 3 | 0.00598138 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00596629 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00596487 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00595673 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00595355 |
| HMGB2 | high mobility group box 2 | 0.0059502 |
| GOLIM4 | golgi integral membrane protein 4 | 0.00586959 |
| AEBP1 | AE binding protein 1 | 0.00585846 |
| ABHD2 | abhydrolase domain containing 2 | 0.00583988 |
| EREG | epiregulin | 0.00581392 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.00580113 |
| KLK6 | kallikrein-related peptidase 6 | 0.00577788 |
| CTSK | cathepsin K | 0.00576373 |
| ZNF423 | zinc finger protein 423 | 0.00576187 |
| DACH1 | dachshund family transcription factor 1 | 0.00573835 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00572256 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00568531 |
| ADD3 | adducin 3 (gamma) | 0.0056789 |
| GLTP | glycolipid transfer protein | 0.00567873 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00567158 |
| PNMA8A | PNMA family member 8A | 0.00566079 |
| WASF1 | WAS protein family, member 1 | 0.00565619 |
| TSPYL5 | TSPY-like 5 | 0.00564047 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00561716 |
| CD1B | CD1b molecule | 0.00560743 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0055841 |
| LPIN2 | lipin 2 | 0.00557861 |
| RCAN1 | regulator of calcineurin 1 | 0.00556138 |
| NNMT | nicotinamide N-methyltransferase | 0.00555085 |
| PHF20 | PHD finger protein 20 | 0.00552401 |
| NFIB | nuclear factor I/B | 0.00550456 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00549482 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.00547808 |
| DSE | dermatan sulfate epimerase | 0.00545706 |
| ZNF44 | zinc finger protein 44 | 0.00543122 |
| MITF | microphthalmia-associated transcription factor | 0.00541273 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00539124 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00538217 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00537977 |
| EPYC | epiphycan | 0.00536301 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00533995 |
| FAM13A | family with sequence similarity 13, member A | 0.00533063 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00533027 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00532591 |
| OLFML2B | olfactomedin-like 2B | 0.00530443 |
| PDE10A | phosphodiesterase 10A | 0.00530248 |
| BTG3 | BTG family, member 3 | 0.00529884 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00529171 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | 0.00527991 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00527556 |
| TPD52L1 | tumor protein D52-like 1 | 0.00527475 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00527114 |
| SC5D | sterol-C5-desaturase | 0.00526331 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00526246 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.00525775 |
| IL1R1 | interleukin 1 receptor, type I | 0.00522401 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.00522149 |
| KRT19 | keratin 19, type I | 0.00521308 |
| DIXDC1 | DIX domain containing 1 | 0.00520509 |
| MMD | monocyte to macrophage differentiation-associated | 0.00520323 |
| RANBP9 | RAN binding protein 9 | 0.00519611 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00519007 |
| PENK | proenkephalin | 0.00518851 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.00518453 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00518169 |
| ACTB | actin, beta | 0.0051758 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.00517316 |
| ASS1 | argininosuccinate synthase 1 | 0.0051599 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00515853 |
| LRRC15 | leucine rich repeat containing 15 | 0.00515409 |
| C1R | complement component 1, r subcomponent | 0.00514925 |
| ACAN | aggrecan | 0.00514492 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00514312 |
| MMP3 | matrix metallopeptidase 3 | 0.00514196 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0051268 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.00511977 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0051171 |
| GPX1 | glutathione peroxidase 1 | 0.0051106 |
| FAS | Fas cell surface death receptor | 0.00510812 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.00510643 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00510413 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00506991 |
| PDGFC | platelet derived growth factor C | 0.00506551 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.00506317 |
| WBP5 | WW domain binding protein 5 | 0.00505548 |
| GMPR | guanosine monophosphate reductase | 0.0050411 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00503739 |
| KLHL24 | kelch-like family member 24 | 0.00503106 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.0050126 |
| SORD | sorbitol dehydrogenase | 0.00500888 |
| GDF15 | growth differentiation factor 15 | 0.00500356 |
| ZNF652 | zinc finger protein 652 | 0.00499833 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00499211 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00499025 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00498894 |
| DAZAP2 | DAZ associated protein 2 | 0.00498214 |
| PLAU | plasminogen activator, urokinase | 0.00497856 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00496894 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00496493 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0049615 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00496058 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00495814 |
| PF4 | platelet factor 4 | 0.00494842 |
| PFKM | phosphofructokinase, muscle | 0.0049228 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00490894 |
| MFAP5 | microfibrillar associated protein 5 | 0.00490861 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.00490303 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00490241 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00489687 |
| THBS1 | thrombospondin 1 | 0.00488665 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00488592 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00488543 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00488189 |
| DNTT | DNA nucleotidylexotransferase | 0.00488186 |
| SERINC5 | serine incorporator 5 | 0.00487541 |
| SEPTIN11 | septin 11 | 0.00487053 |
| FBLN1 | fibulin 1 | 0.00485275 |
| KLHL21 | kelch-like family member 21 | 0.0048521 |
| NRXN2 | neurexin 2 | 0.00480779 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.00480587 |
| DUSP2 | dual specificity phosphatase 2 | 0.0047999 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.0047962 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.00478744 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.00476327 |
| TRIM38 | tripartite motif containing 38 | 0.00476114 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00475856 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.0047463 |
| STK38 | serine/threonine kinase 38 | 0.00474586 |
| CYRIA | CYFIP related Rac1 interactor A | 0.00473409 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 | 0.00473198 |
| HMOX1 | heme oxygenase 1 | 0.00473196 |
| CEP170 | centrosomal protein 170kDa | 0.0047293 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00472712 |
| CD44 | CD44 molecule (Indian blood group) | 0.00472289 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00471941 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00470095 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00469293 |
| CBX5 | chromobox homolog 5 | 0.00468735 |
| EPHA3 | EPH receptor A3 | 0.00468694 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00466607 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00465636 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00465555 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00463948 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00463878 |
| CBX3 | chromobox homolog 3 | 0.00463769 |
| MICB | MHC class I polypeptide-related sequence B | 0.00463747 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00463655 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00463452 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0167951 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0124976 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0116021 |
| TBX2 | T-box 2 | -0.010391 |
| STAP2 | signal transducing adaptor family member 2 | -0.0103567 |
| LTF | lactotransferrin | -0.0100801 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00990662 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00989223 |
| SFTPA2 | surfactant protein A2 | -0.00920532 |
| CDCA4 | cell division cycle associated 4 | -0.00915006 |
| PODXL | podocalyxin-like | -0.00911272 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00900228 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00890355 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.0087473 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00861611 |
| OLFML2A | olfactomedin-like 2A | -0.00859162 |
| CALML5 | calmodulin-like 5 | -0.00847849 |
| IL32 | interleukin 32 | -0.00839482 |
| FCGBP | Fc fragment of IgG binding protein | -0.00838764 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00812237 |
| KRT6A | keratin 6A, type II | -0.00805729 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00792083 |
| CA2 | carbonic anhydrase II | -0.00765781 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00765752 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00760736 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.00757044 |
| PYCARD | PYD and CARD domain containing | -0.00746932 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00731547 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00727154 |
| KYNU | kynureninase | -0.00722306 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00714854 |
| SFTPB | surfactant protein B | -0.00711659 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00711462 |
| STK10 | serine/threonine kinase 10 | -0.00707991 |
| NKG7 | natural killer cell granule protein 7 | -0.00705804 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00702153 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00700817 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00697228 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00691483 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00691149 |
| ABHD17A | abhydrolase domain containing 17A | -0.00689391 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00689254 |
| SLC38A10 | solute carrier family 38, member 10 | -0.00689182 |
| TSPAN8 | tetraspanin 8 | -0.00687449 |
| RAB38 | RAB38, member RAS oncogene family | -0.00687211 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00686463 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 | -0.00685756 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00685483 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00679003 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00678682 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00669738 |
| MEIS2 | Meis homeobox 2 | -0.00669178 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00666228 |
| COL1A2 | collagen, type I, alpha 2 | -0.00665699 |
| TARP | TCR gamma alternate reading frame protein | -0.00660925 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -0.00655609 |
| MPZL2 | myelin protein zero-like 2 | -0.00653892 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00652305 |
| CANT1 | calcium activated nucleotidase 1 | -0.00651033 |
| OBSL1 | obscurin-like 1 | -0.00643324 |
| KRT5 | keratin 5, type II | -0.00643105 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00635952 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.00635716 |
| PEG3 | paternally expressed 3 | -0.00634198 |
| GUCY2C | guanylate cyclase 2C | -0.00630877 |
| TCTA | T-cell leukemia translocation altered | -0.00630454 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00627983 |
| DMD | dystrophin | -0.00623217 |
| MYBPC1 | myosin binding protein C, slow type | -0.00622629 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00621544 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | -0.00621176 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00615657 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00613811 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00612258 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00610057 |
| PON3 | paraoxonase 3 | -0.00607939 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00607433 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00606518 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00605831 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00600724 |
| TESC | tescalcin | -0.00600064 |
| PLPP2 | phospholipid phosphatase 2 | -0.00599596 |
| TCF21 | transcription factor 21 | -0.00596502 |
| GCH1 | GTP cyclohydrolase 1 | -0.00588633 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | -0.00588493 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00588371 |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) | -0.00583143 |
| A2M | alpha-2-macroglobulin | -0.00582676 |
| CTSG | cathepsin G | -0.00581772 |
| MLPH | melanophilin | -0.00581094 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00580972 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00580314 |
| HOPX | HOP homeobox | -0.00578586 |
| ZNF589 | zinc finger protein 589 | -0.00578464 |
| NES | nestin | -0.00576445 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00574752 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00573296 |
| ITGB4 | integrin, beta 4 | -0.00567632 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | -0.00566719 |
| NID1 | nidogen 1 | -0.00566026 |
| TGFB1 | transforming growth factor, beta 1 | -0.00564346 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00562668 |
| ELP1 | elongator acetyltransferase complex subunit 1 | -0.00561902 |
| GPATCH8 | G patch domain containing 8 | -0.0056037 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00560342 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.00559457 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00559283 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00558338 |
| KRT17 | keratin 17, type I | -0.00558307 |
| TNS3 | tensin 3 | -0.00557972 |
| DUS1L | dihydrouridine synthase 1-like (S. cerevisiae) | -0.00555458 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00555099 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | -0.00553116 |
| S100P | S100 calcium binding protein P | -0.00551135 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | -0.00550186 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.0054801 |
| MLEC | malectin | -0.00547029 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00546147 |
| KLC1 | kinesin light chain 1 | -0.00542398 |
| IL2RG | interleukin 2 receptor, gamma | -0.00541387 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | -0.00539042 |
| CSTA | cystatin A (stefin A) | -0.00536047 |
| CLDN8 | claudin 8 | -0.00535165 |
| JMJD6 | jumonji domain containing 6 | -0.00534767 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00534321 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00531832 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00522452 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00521926 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00521061 |
| CST7 | cystatin F (leukocystatin) | -0.00520878 |
| COL3A1 | collagen, type III, alpha 1 | -0.00520621 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.00517153 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00516791 |
| PCNT | pericentrin | -0.00516368 |
| MSX1 | msh homeobox 1 | -0.00515101 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.0051368 |
| PER3 | period circadian clock 3 | -0.00513568 |
| ATP5MJ | ATP synthase membrane subunit j | -0.00511246 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00509299 |
| GOLGA8H | golgin A8 family, member H | -0.00508952 |
| BSG | basigin (Ok blood group) | -0.00506759 |
| ZNF395 | zinc finger protein 395 | -0.00506746 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0050579 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -0.00505691 |
| CTSW | cathepsin W | -0.00505461 |
| RPS5 | ribosomal protein S5 | -0.00503661 |
| NOP53 | NOP53 ribosome biogenesis factor | -0.00503111 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00502745 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | -0.00500245 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | -0.00499366 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00499102 |
| PLXNC1 | plexin C1 | -0.0049856 |
| MRPL23 | mitochondrial ribosomal protein L23 | -0.00498475 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00498091 |
| FAT2 | FAT atypical cadherin 2 | -0.00497886 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00497833 |
| TSPAN7 | tetraspanin 7 | -0.00496423 |
| OPN3 | opsin 3 | -0.00496248 |
| RCAN2 | regulator of calcineurin 2 | -0.00496123 |
| CTSH | cathepsin H | -0.00493419 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00490397 |
| IER2 | immediate early response 2 | -0.00489321 |
| GNLY | granulysin | -0.00486471 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -0.00485902 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | -0.00485454 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00484221 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00484065 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.00482166 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.00481663 |
| SAMM50 | SAMM50 sorting and assembly machinery component | -0.00481198 |
| PRF1 | perforin 1 (pore forming protein) | -0.00480835 |
| ANGPT2 | angiopoietin 2 | -0.00480531 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) | -0.00479855 |
| EDN3 | endothelin 3 | -0.00479141 |
| MYDGF | myeloid-derived growth factor | -0.00478947 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00478783 |
| PLXNA2 | plexin A2 | -0.0047862 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | -0.0047796 |
| SPRR1B | small proline-rich protein 1B | -0.00477689 |
| ILVBL | ilvB (bacterial acetolactate synthase)-like | -0.00475455 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00475069 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.0047477 |
| GIMAP5 | GTPase, IMAP family member 5 | -0.00473991 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 | -0.0047395 |
| ACACA | acetyl-CoA carboxylase alpha | -0.00472784 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00472518 |
| TOR1A | torsin family 1, member A (torsin A) | -0.0047229 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00472089 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | -0.00471919 |
| CA4 | carbonic anhydrase IV | -0.00469917 |
| RPL36 | ribosomal protein L36 | -0.00468391 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00467204 |
| DSP | desmoplakin | -0.00466452 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | -0.00466239 |
| RHOC | ras homolog family member C | -0.00466101 |
| FAM3C | family with sequence similarity 3, member C | -0.004644 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00464067 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.00463892 |
| SFTPC | surfactant protein C | -0.00463421 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00463195 |
| POSTN | periostin, osteoblast specific factor | -0.0045961 |
| HOMER3 | homer scaffolding protein 3 | -0.00459588 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00458151 |
| NUCB2 | nucleobindin 2 | -0.00456815 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.00456264 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00456011 |
| SSR4 | signal sequence receptor, delta | -0.00455298 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00454955 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00454275 |
| INAVA | innate immunity activator | -0.00453597 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00453297 |
| CLIC5 | chloride intracellular channel 5 | -0.00453007 |
| WFS1 | Wolfram syndrome 1 (wolframin) | -0.00452197 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00451832 |
| AIM2 | absent in melanoma 2 | -0.00451127 |
| ZW10 | zw10 kinetochore protein | -0.00450726 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00449208 |
| KRT16 | keratin 16, type I | -0.00449015 |
| KRT6B | keratin 6B, type II | -0.00448945 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00448244 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) | -0.0044624 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00446157 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00444274 |
| EIF2D | eukaryotic translation initiation factor 2D | -0.00442223 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00441561 |
| LYPLA1 | lysophospholipase I | -0.00439944 |
| DYSF | dysferlin | -0.00437038 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00436239 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00436155 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -0.00435914 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | -0.00435729 |
| NDUFB2 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | -0.00435541 |
| PLS1 | plastin 1 | -0.00435299 |
| AMPD1 | adenosine monophosphate deaminase 1 | -0.00435098 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.00435073 |
| ATP11B | ATPase, class VI, type 11B | -0.00434575 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00434314 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.00434001 |
| GPR171 | G protein-coupled receptor 171 | -0.0043369 |
| DENND4B | DENN/MADD domain containing 4B | -0.00432837 |
| C7 | complement component 7 | -0.00432373 |
| OPHN1 | oligophrenin 1 | -0.00432291 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00430592 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00429674 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00428944 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00427918 |
| MMP1 | matrix metallopeptidase 1 | -0.00426819 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00426592 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00426058 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00425204 |
