ITGA3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)|The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 3675)
External Link https://ncbi.nlm.nih.gov/gene/3675
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Genes

499 genes differentially expressed following the ITGA3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0123159
BASP1 brain abundant, membrane attached signal protein 1 0.0113442
FGFR3 fibroblast growth factor receptor 3 0.00889608
MAP7 microtubule-associated protein 7 0.00848785
WDR7 WD repeat domain 7 0.00821554
NEFH neurofilament, heavy polypeptide 0.00805607
DMD dystrophin 0.00764475
ACKR3 atypical chemokine receptor 3 0.00736071
HMG20B high mobility group 20B 0.00702116
CXCL12 chemokine (C-X-C motif) ligand 12 0.00676339
MEIS1 Meis homeobox 1 0.0063865
NPTX2 neuronal pentraxin II 0.00632006
NCALD neurocalcin delta 0.00625379
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00624047
METTL7A methyltransferase like 7A 0.00623489
SCG5 secretogranin V 0.00619982
AUTS2 autism susceptibility candidate 2 0.0061498
NAV2 neuron navigator 2 0.00608695
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.00601419
SPEN spen family transcriptional repressor 0.00600916
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.00600904
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00600511
ADM adrenomedullin 0.00595378
TSPO translocator protein (18kDa) 0.00592189
NDRG1 N-myc downstream regulated 1 0.00588435
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.00580982
RTN1 reticulon 1 0.00578183
CRISP3 cysteine-rich secretory protein 3 0.00577482
DCLK1 doublecortin-like kinase 1 0.00573789
CHEK2 checkpoint kinase 2 0.00571041
ADCY1 adenylate cyclase 1 (brain) 0.00569312
DUSP2 dual specificity phosphatase 2 0.00566756
DTX4 deltex 4, E3 ubiquitin ligase 0.00559583
THBS1 thrombospondin 1 0.00559181
PLAGL1 pleiomorphic adenoma gene-like 1 0.0055849
ACOT9 acyl-CoA thioesterase 9 0.00556831
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00552849
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00552568
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00548284
HMGN3 high mobility group nucleosomal binding domain 3 0.00542145
EPHB2 EPH receptor B2 0.00539834
ADD3 adducin 3 (gamma) 0.00538767
OCRL oculocerebrorenal syndrome of Lowe 0.00537201
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.0053185
IGFBP5 insulin-like growth factor binding protein 5 0.00527045
FAM13A family with sequence similarity 13, member A 0.00526989
CBX5 chromobox homolog 5 0.00526296
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00525211
OLFM1 olfactomedin 1 0.0052243
RAP1GAP2 RAP1 GTPase activating protein 2 0.00521825
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00521473
NEFM neurofilament, medium polypeptide 0.00520266
HMGN5 high mobility group nucleosome binding domain 5 0.00519076
ZIC1 Zic family member 1 0.00513827
ZNF395 zinc finger protein 395 0.00513277
ADARB1 adenosine deaminase, RNA-specific, B1 0.00512487
CAPN3 calpain 3, (p94) 0.00512097
INA internexin neuronal intermediate filament protein, alpha 0.00511529
JARID2 jumonji, AT rich interactive domain 2 0.00508419
BICC1 BicC family RNA binding protein 1 0.00506732
QKI QKI, KH domain containing, RNA binding 0.00503182
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.00501797
TUBA4A tubulin, alpha 4a 0.00500722
LY75 lymphocyte antigen 75 0.00499083
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00499065
UNC119B unc-119 homolog B (C. elegans) 0.00498996
S100A8 S100 calcium binding protein A8 0.00497119
SNAP25 synaptosomal-associated protein, 25kDa 0.0049637
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.00495159
NRCAM neuronal cell adhesion molecule 0.00494559
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00493936
STEAP3 STEAP family member 3, metalloreductase 0.00492533
COL7A1 collagen, type VII, alpha 1 0.00490972
SFRP1 secreted frizzled-related protein 1 0.00488414
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.00487147
ZFP36L2 ZFP36 ring finger protein-like 2 0.00483945
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00483865
SYNJ1 synaptojanin 1 0.00480518
USP48 ubiquitin specific peptidase 48 0.00477366
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00476687
HIC2 hypermethylated in cancer 2 0.00476108
PBLD phenazine biosynthesis-like protein domain containing 0.00472314
CDA cytidine deaminase 0.00472245
ANPEP alanyl (membrane) aminopeptidase 0.0047211
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.0047033
LIN28A lin-28 homolog A (C. elegans) 0.00466814
DKFZP586I1420 uncharacterized protein DKFZp586I1420 0.00466657
CTSV cathepsin V 0.00463607
TADA2A transcriptional adaptor 2A 0.00462329
IGSF3 immunoglobulin superfamily, member 3 0.00462298
HSPA1A heat shock 70kDa protein 1A 0.00461225
KIF1B kinesin family member 1B 0.00460592
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.004599
SALL1 spalt-like transcription factor 1 0.00459548
CADM1 cell adhesion molecule 1 0.00457739
PLSCR3 phospholipid scramblase 3 0.00457523
BCR breakpoint cluster region 0.00456403
SMC1A structural maintenance of chromosomes 1A 0.00455283
PFKL phosphofructokinase, liver 0.0045483
TRIM29 tripartite motif containing 29 0.00454454
KIF20A kinesin family member 20A 0.00453507
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 0.00452226
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00451929
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00449088
CHGB chromogranin B 0.00448571
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00448358
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00447426
STMN2 stathmin 2 0.00447119
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00446632
TFPI2 tissue factor pathway inhibitor 2 0.00445395
VEGFA vascular endothelial growth factor A 0.00443899
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00441694
SEPTIN11 septin 11 0.00439672
RSRP1 arginine/serine-rich protein 1 0.00438624
BIN1 bridging integrator 1 0.00438614
SYNGR3 synaptogyrin 3 0.00438369
TNC tenascin C 0.00437689
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00437282
GPM6B glycoprotein M6B 0.00436972
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00433731
MAN1A2 mannosidase, alpha, class 1A, member 2 0.00433655
FLT3 fms-related tyrosine kinase 3 0.00432127
PNISR PNN-interacting serine/arginine-rich protein 0.00431746
LY6E lymphocyte antigen 6 complex, locus E 0.00431342
G0S2 G0/G1 switch 2 0.00430927
FLNA filamin A, alpha 0.00430493
RBM34 RNA binding motif protein 34 0.00429772
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00429378
SLC25A46 solute carrier family 25, member 46 0.00427575
TTC28 tetratricopeptide repeat domain 28 0.00423509
MAST4 microtubule associated serine/threonine kinase family member 4 0.00420615
TMEM47 transmembrane protein 47 0.00420261
COL9A3 collagen, type IX, alpha 3 0.00419441
MN1 meningioma (disrupted in balanced translocation) 1 0.00418907
CDK14 cyclin-dependent kinase 14 0.00418816
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00418395
PERP PERP, TP53 apoptosis effector 0.00416932
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00416783
FAM117A family with sequence similarity 117, member A 0.00416423
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.00416152
FOXD1 forkhead box D1 0.00414548
BLNK B-cell linker 0.00413149
ISYNA1 inositol-3-phosphate synthase 1 0.00412875
GLUD1 glutamate dehydrogenase 1 0.0041193
NID2 nidogen 2 (osteonidogen) 0.00411889
NTS neurotensin 0.00407622
KIAA0513 KIAA0513 0.00407298
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00407131
LPAR1 lysophosphatidic acid receptor 1 0.00405497
PUF60 poly-U binding splicing factor 60KDa 0.00402813
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00402531
SHOX2 short stature homeobox 2 0.00400854
L1CAM L1 cell adhesion molecule 0.00400549
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.00400403
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00399426
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.00399068
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00398808
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00398465
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.00398317
TRAF5 TNF receptor-associated factor 5 0.00398144
MDC1 mediator of DNA-damage checkpoint 1 0.00397204
NOTCH2NL notch 2 N-terminal like 0.00397149
MOK MOK protein kinase 0.00396074
PON2 paraoxonase 2 0.0039423
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 0.00393186
ADCY9 adenylate cyclase 9 0.00391645
CAPN2 calpain 2, (m/II) large subunit 0.00390145
PAX5 paired box 5 0.00388107
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.00388012
PDLIM4 PDZ and LIM domain 4 0.00386486
SIK1 salt-inducible kinase 1 0.003864
GLDC glycine dehydrogenase (decarboxylating) 0.00386363
PRODH proline dehydrogenase (oxidase) 1 0.00385449
H1-10 H1.10 linker histone 0.00385311
NANOG Nanog homeobox 0.00384542
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00384349
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00384336
PLEK pleckstrin 0.00383886
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00383292
DEPTOR DEP domain containing MTOR-interacting protein 0.00382542
VRK2 vaccinia related kinase 2 0.00382399
RAB29 RAB29, member RAS oncogene family 0.00381636
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 0.00381344
INTS1 integrator complex subunit 1 0.00380982
MAMLD1 mastermind-like domain containing 1 0.00380436
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00380027
LONP2 lon peptidase 2, peroxisomal 0.00378994
FTO fat mass and obesity associated 0.00378353
FSCN1 fascin actin-bundling protein 1 0.00377814
RABGAP1L RAB GTPase activating protein 1-like 0.00377773
ATP10D ATPase, class V, type 10D 0.00377567
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00377091
PGAM1 phosphoglycerate mutase 1 (brain) 0.00376443
FST follistatin 0.00375899
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00375567
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.0037545
CD200 CD200 molecule 0.00374588
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.00374283
SETBP1 SET binding protein 1 0.00374213
FGB fibrinogen beta chain 0.00374198
TMX4 thioredoxin-related transmembrane protein 4 0.00373897
INTS8 integrator complex subunit 8 0.00373486
DST dystonin 0.00373423
NCOA1 nuclear receptor coactivator 1 0.00372932
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00372443
ANXA6 annexin A6 0.00372233
CCNA2 cyclin A2 0.00371511
GAL galanin/GMAP prepropeptide 0.00370967
TSPYL4 TSPY-like 4 0.00370096
DOP1A DOP1 leucine zipper like protein A 0.0036955
RAD23B RAD23 homolog B (S. cerevisiae) 0.00368482
KLF10 Kruppel-like factor 10 0.00366835
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.00365996
CPE carboxypeptidase E 0.00364171
BAHCC1 BAH domain and coiled-coil containing 1 0.00363937
SH3YL1 SH3 and SYLF domain containing 1 0.00363339
EPHB6 EPH receptor B6 0.0036332
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00363005
CDC25B cell division cycle 25B 0.0036259
COL9A2 collagen, type IX, alpha 2 0.00362391
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00362129
PAIP2B poly(A) binding protein interacting protein 2B 0.00362062
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00361505
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 0.00360512
PHIP pleckstrin homology domain interacting protein 0.00360477
LPAR2 lysophosphatidic acid receptor 2 0.00360401
HBD hemoglobin, delta 0.00358637
RHOB ras homolog family member B 0.0035819
PLXNB2 plexin B2 0.00358134
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00356757
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.00356614
C1RL complement component 1, r subcomponent-like 0.00356268
CBX7 chromobox homolog 7 0.0035587
DZIP1 DAZ interacting zinc finger protein 1 0.00355538
DCT dopachrome tautomerase 0.00355401
DCAF8 DDB1 and CUL4 associated factor 8 0.00355171
MGLL monoglyceride lipase 0.00355047
DGKZ diacylglycerol kinase, zeta 0.00354722
INSM1 insulinoma-associated 1 0.00354016
RCAN1 regulator of calcineurin 1 0.00353885
ENO1 enolase 1, (alpha) 0.00352886
PBX3 pre-B-cell leukemia homeobox 3 0.00351925
SMTN smoothelin 0.0035175
L1TD1 LINE-1 type transposase domain containing 1 0.00351458
LBR lamin B receptor 0.00348552
NCOR2 nuclear receptor corepressor 2 0.00348033
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00347098
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.00347049
NRGN neurogranin (protein kinase C substrate, RC3) 0.00346809
AHI1 Abelson helper integration site 1 0.00346105

decreased expression

Symbol Name Standardized Value
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0101547
XIC X chromosome inactivation center -0.00869908
JPT1 Jupiter microtubule associated homolog 1 -0.00841274
IFI27 interferon, alpha-inducible protein 27 -0.00830056
GPNMB glycoprotein (transmembrane) nmb -0.00809663
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00807554
FABP4 fatty acid binding protein 4, adipocyte -0.0078206
PGC progastricsin (pepsinogen C) -0.00772098
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00711897
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00697154
BAMBI BMP and activin membrane-bound inhibitor -0.00696887
MGP matrix Gla protein -0.00689797
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00671956
CLDND1 claudin domain containing 1 -0.00669775
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00664512
TSPAN8 tetraspanin 8 -0.0066227
SPARCL1 SPARC-like 1 (hevin) -0.00654065
MOXD1 monooxygenase, DBH-like 1 -0.00651489
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00650939
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -0.00637729
MXRA7 matrix-remodelling associated 7 -0.00634965
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00633995
SFTPB surfactant protein B -0.0062254
EMP1 epithelial membrane protein 1 -0.00621932
CTSB cathepsin B -0.00616539
PMP22 peripheral myelin protein 22 -0.00613672
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00610775
GOLT1B golgi transport 1B -0.00610144
CCN2 cellular communication network factor 2 -0.0059643
NUP85 nucleoporin 85kDa -0.00595881
CLIC5 chloride intracellular channel 5 -0.00592953
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00590416
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00589177
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00587939
FAM198B family with sequence similarity 198, member B -0.00587053
EFNA1 ephrin-A1 -0.00586408
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00585994
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00584231
HNMT histamine N-methyltransferase -0.00581797
AKAP1 A kinase (PRKA) anchor protein 1 -0.00576857
A2M alpha-2-macroglobulin -0.00574115
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00565661
SFTPD surfactant protein D -0.0056358
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00555424
S100P S100 calcium binding protein P -0.00550596
ETV5 ets variant 5 -0.00547678
ANXA1 annexin A1 -0.00546705
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00544317
CALCRL calcitonin receptor-like -0.00534039
AGR2 anterior gradient 2 -0.00532591
GNAS GNAS complex locus -0.00529506
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00529363
TMC5 transmembrane channel-like 5 -0.00527787
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00527189
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00526301
MRPS7 mitochondrial ribosomal protein S7 -0.00524089
TIMP2 TIMP metallopeptidase inhibitor 2 -0.00521148
SFTPA2 surfactant protein A2 -0.00518529
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00516167
CCL20 chemokine (C-C motif) ligand 20 -0.00515832
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00513616
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0051268
PEG3 paternally expressed 3 -0.00512391
TESC tescalcin -0.00512345
RGCC regulator of cell cycle -0.00511178
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00508484
CD99 CD99 molecule -0.00504421
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00504056
SRSF1 serine/arginine-rich splicing factor 1 -0.00502567
BMP4 bone morphogenetic protein 4 -0.00500347
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.00500155
EXOC5 exocyst complex component 5 -0.00492789
ASPN asporin -0.0049267
ESR1 estrogen receptor 1 -0.00489176
LAMP3 lysosomal-associated membrane protein 3 -0.00486572
CCNB1 cyclin B1 -0.00485379
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00483368
CTSH cathepsin H -0.00483341
CFB complement factor B -0.00483225
COL3A1 collagen, type III, alpha 1 -0.00481725
LCN2 lipocalin 2 -0.00481712
GSTZ1 glutathione S-transferase zeta 1 -0.00481016
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00479614
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.00479602
CFI complement factor I -0.00479165
PLAAT3 phospholipase A and acyltransferase 3 -0.00478726
POSTN periostin, osteoblast specific factor -0.00477828
CES1 carboxylesterase 1 -0.00475438
ACP5 acid phosphatase 5, tartrate resistant -0.00474885
CTSE cathepsin E -0.00471649
MRPL58 mitochondrial ribosomal protein L58 -0.00469638
UBB ubiquitin B -0.00468054
TSPAN1 tetraspanin 1 -0.00467283
RETREG1 reticulophagy regulator 1 -0.00466406
PRRX1 paired related homeobox 1 -0.00466195
PPARG peroxisome proliferator-activated receptor gamma -0.00465988
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00464383
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0046409
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00464007
APOC1 apolipoprotein C-I -0.00462528
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00460365
TMEM100 transmembrane protein 100 -0.00459785
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00459021
H1-2 H1.2 linker histone, cluster member -0.00457887
CLEC2B C-type lectin domain family 2, member B -0.00454792
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.00453679
NIP7 NIP7, nucleolar pre-rRNA processing protein -0.00452605
FIGF c-fos induced growth factor (vascular endothelial growth factor D) -0.00450437
YIPF5 Yip1 domain family, member 5 -0.00449
FILIP1L filamin A interacting protein 1-like -0.00448311
SST somatostatin -0.00447017
ATP10B ATPase, class V, type 10B -0.00445974
ZNF217 zinc finger protein 217 -0.00445304
S100A10 S100 calcium binding protein A10 -0.00440003
CAPG capping protein (actin filament), gelsolin-like -0.00439668
C1QA complement component 1, q subcomponent, A chain -0.00439448
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00438917
PTPRK protein tyrosine phosphatase, receptor type, K -0.00437089
MED13 mediator complex subunit 13 -0.00436897
TMEM14B transmembrane protein 14B -0.0043285
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00430479
JAG1 jagged 1 -0.00429383
SFTPC surfactant protein C -0.00428732
KCTD20 potassium channel tetramerization domain containing 20 -0.00424124
GLUL glutamate-ammonia ligase -0.00423205
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00423184
GRB2 growth factor receptor-bound protein 2 -0.00420916
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -0.00420759
AKR1C2 aldo-keto reductase family 1, member C2 -0.00420159
EXPH5 exophilin 5 -0.00419987
RFC2 replication factor C (activator 1) 2, 40kDa -0.0041862
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00416815
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00416669
CAVIN2 caveolae associated protein 2 -0.00415974
UBE2H ubiquitin-conjugating enzyme E2H -0.00413994
KRT81 keratin 81, type II -0.00413398
AMZ2 archaelysin family metallopeptidase 2 -0.0041298
HSPE1 heat shock 10kDa protein 1 -0.00411927
BCHE butyrylcholinesterase -0.00411783
LYPD1 LY6/PLAUR domain containing 1 -0.00411251
GNLY granulysin -0.00410938
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00410224
CFAP20 cilia and flagella associated protein 20 -0.00409953
OASL 2'-5'-oligoadenylate synthetase-like -0.0040942
ADORA2B adenosine A2b receptor -0.00407461
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00407281
ADIRF adipogenesis regulatory factor -0.00406649
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00406473
AREG amphiregulin -0.00405949
ACSS3 acyl-CoA synthetase short-chain family member 3 -0.00404558
SOX9 SRY (sex determining region Y)-box 9 -0.00404384
SHB Src homology 2 domain containing adaptor protein B -0.00402969
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00402656
EIF5 eukaryotic translation initiation factor 5 -0.00400736
CTSK cathepsin K -0.00400287
PTRH2 peptidyl-tRNA hydrolase 2 -0.00396058
ADAM9 ADAM metallopeptidase domain 9 -0.0039575
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0039459
MMP11 matrix metallopeptidase 11 -0.00392406
HIST1H2BK histone cluster 1, H2bk -0.00392179
SCAMP1 secretory carrier membrane protein 1 -0.00391408
MMP7 matrix metallopeptidase 7 -0.00390491
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0038965
PRDX1 peroxiredoxin 1 -0.00389226
TPD52 tumor protein D52 -0.00389027
MARCO macrophage receptor with collagenous structure -0.00386486
GDF15 growth differentiation factor 15 -0.00386409
MMP2 matrix metallopeptidase 2 -0.00386176
CLDN18 claudin 18 -0.00384852
TFRC transferrin receptor -0.00383639
MXRA5 matrix-remodelling associated 5 -0.00382756
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00382711
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00381757
CERS2 ceramide synthase 2 -0.00380884
AQP4 aquaporin 4 -0.00380835
CHPT1 choline phosphotransferase 1 -0.00379939
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00376919
LY96 lymphocyte antigen 96 -0.00376752
MYO5C myosin VC -0.00376075
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00375077
GTF2I general transcription factor IIi -0.00373432
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.00372651
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00372252
CCDC47 coiled-coil domain containing 47 -0.00372144
CD1E CD1e molecule -0.0037188
MMP16 matrix metallopeptidase 16 (membrane-inserted) -0.00370965
IFNGR1 interferon gamma receptor 1 -0.00370362
RDX radixin -0.0036851
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -0.00366144
ARF4 ADP-ribosylation factor 4 -0.00365902
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00364791
RXYLT1 ribitol xylosyltransferase 1 -0.00364232
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00364031
IFRD2 interferon-related developmental regulator 2 -0.00363753
FGFR1 fibroblast growth factor receptor 1 -0.00363114
MPDU1 mannose-P-dolichol utilization defect 1 -0.00362399
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.00362058
NME6 NME/NM23 nucleoside diphosphate kinase 6 -0.00361346
PRNP prion protein -0.00361326
MME membrane metallo-endopeptidase -0.00360855
CPB2 carboxypeptidase B2 (plasma) -0.00360683
VAV3 vav 3 guanine nucleotide exchange factor -0.00360661
IREB2 iron-responsive element binding protein 2 -0.00360448
MOB4 MOB family member 4, phocein -0.0036014
ISG15 ISG15 ubiquitin-like modifier -0.00359789
ANXA10 annexin A10 -0.00359486
FAM169A family with sequence similarity 169, member A -0.00359198
RGS10 regulator of G-protein signaling 10 -0.00357943
MED1 mediator complex subunit 1 -0.00357506
EXT1 exostosin glycosyltransferase 1 -0.00356541
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -0.00356329
DNASE2 deoxyribonuclease II, lysosomal -0.00356248
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0035533
TLR4 toll-like receptor 4 -0.00355114
TGFB2 transforming growth factor, beta 2 -0.0035459
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00353732
MYBPC1 myosin binding protein C, slow type -0.00351059
DIPK1A divergent protein kinase domain 1A -0.00350415
FYB1 FYN binding protein 1 -0.00350202
CIAO2B cytosolic iron-sulfur assembly component 2B -0.00350028
CEMIP cell migration inducing protein, hyaluronan binding -0.00349977
RNASET2 ribonuclease T2 -0.0034996
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.00349814
F3 coagulation factor III (thromboplastin, tissue factor) -0.00349103
AKR1C1 aldo-keto reductase family 1, member C1 -0.00348071
PARVA parvin, alpha -0.00347887
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00347394
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00347028
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.00346646
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -0.00346224
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00345783
HIST3H2A histone cluster 3, H2a -0.00345768
GSAP gamma-secretase activating protein -0.00344608
RAG1 recombination activating gene 1 -0.00344583
GIMAP5 GTPase, IMAP family member 5 -0.00344278
RABGGTB Rab geranylgeranyltransferase, beta subunit -0.00344248
ACOX1 acyl-CoA oxidase 1, palmitoyl -0.00344033
FHL1 four and a half LIM domains 1 -0.00343614
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C -0.00343588
LYZ lysozyme -0.00343266
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.00343089
ADIPOR2 adiponectin receptor 2 -0.00342261
TNF tumor necrosis factor -0.00341883
TMEM70 transmembrane protein 70 -0.00341266
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00341192
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic -0.00340874
TCF12 transcription factor 12 -0.00340874
KLF5 Kruppel-like factor 5 (intestinal) -0.00340872
PTGES prostaglandin E synthase -0.00340791