ITGA3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)|The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 3675)
External Link http://www.ncbi.nlm.nih.gov/gene/3675
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Genes

319 interacting proteins for ITGA3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACP2 acid phosphatase 2, lysosomal
ACTB actin, beta
ACTG1 actin gamma 1
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
ADAM9 ADAM metallopeptidase domain 9
ADD1 adducin 1 (alpha)
ADGRE5 adhesion G protein-coupled receptor E5
ADNP activity-dependent neuroprotector homeobox
AGR2 anterior gradient 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA1 annexin A1
ANXA11 annexin A11
ANXA2 annexin A2
ANXA6 annexin A6
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APMAP adipocyte plasma membrane associated protein
ARF1 ADP-ribosylation factor 1
ARF5 ADP-ribosylation factor 5
ARF6 ADP-ribosylation factor 6
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BIN1 bridging integrator 1
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BSG basigin (Ok blood group)
BTD biotinidase
BTN2A1 butyrophilin, subfamily 2, member A1
CALR calreticulin
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAND1 cullin-associated and neddylation-dissociated 1
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC53 coiled-coil domain containing 53
CD109 CD109 molecule
CD151 CD151 molecule (Raph blood group)
CD276 CD276 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD63 CD63 molecule
CD81 CD81 molecule
CD82 CD82 molecule
CD9 CD9 molecule
CDC42 cell division cycle 42
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDCP1 CUB domain containing protein 1
CDK1 cyclin-dependent kinase 1
CFL1 cofilin 1 (non-muscle)
CHMP4B charged multivesicular body protein 4B
CLDN3 claudin 3
CLIC4 chloride intracellular channel 4
CLN5 ceroid-lipofuscinosis, neuronal 5
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
CLU clusterin
CNN2 calponin 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL5A1 collagen, type V, alpha 1
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COPB1 coatomer protein complex, subunit beta 1
COPZ1 coatomer protein complex, subunit zeta 1
CPNE1 copine I
CRTAP cartilage associated protein
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSK c-src tyrosine kinase
CST4 cystatin S
CSTA cystatin A (stefin A)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSD cathepsin D
DNASE2 deoxyribonuclease II, lysosomal
DNM2 dynamin 2
DPP7 dipeptidyl-peptidase 7
DSG1 desmoglein 1
DSTN destrin (actin depolymerizing factor)
DTYMK deoxythymidylate kinase (thymidylate kinase)
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ECE1 endothelin converting enzyme 1
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
EIF3M eukaryotic translation initiation factor 3, subunit M
EMC1 ER membrane protein complex subunit 1
EML4 echinoderm microtubule associated protein like 4
ENO1 enolase 1, (alpha)
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
ERO1L ERO1-like (S. cerevisiae)
EYS eyes shut homolog (Drosophila)
EZR ezrin
FAM21C family with sequence similarity 21, member C
FBN1 fibrillin 1
FBXO6 F-box protein 6
FCHO2 FCH domain only 2
FEN1 flap structure-specific endonuclease 1
FHL2 four and a half LIM domains 2
FKBP10 FK506 binding protein 10, 65 kDa
FKBP9 FK506 binding protein 9, 63 kDa
FLNA filamin A, alpha
FLNB filamin B, beta
FLNC filamin C, gamma
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
FYN FYN proto-oncogene, Src family tyrosine kinase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAA glucosidase, alpha; acid
GBA glucosidase, beta, acid
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae)
GLMP glycosylated lysosomal membrane protein
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNS glucosamine (N-acetyl)-6-sulfatase
GPA33 glycoprotein A33 (transmembrane)
GUSB glucuronidase, beta
HEXA hexosaminidase A (alpha polypeptide)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HPS5 Hermansky-Pudlak syndrome 5
HSPA13 heat shock protein 70kDa family, member 13
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HYOU1 hypoxia up-regulated 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGF2R insulin-like growth factor 2 receptor
ILF3 interleukin enhancer binding factor 3, 90kDa
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
IWS1 IWS1 homolog (S. cerevisiae)
KIAA1033 KIAA1033
KIF5B kinesin family member 5B
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT1 keratin 1, type II
L1CAM L1 cell adhesion molecule
LAMA4 laminin, alpha 4
LAMA5 laminin, alpha 5
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LDHA lactate dehydrogenase A
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS8 lectin, galactoside-binding, soluble, 8
LNPEP leucyl/cystinyl aminopeptidase
LPCAT2 lysophosphatidylcholine acyltransferase 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC57 leucine rich repeat containing 57
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
M6PR mannose-6-phosphate receptor (cation dependent)
MAGED2 melanoma antigen family D2
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP4 microtubule-associated protein 4
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MCAM melanoma cell adhesion molecule
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MOGS mannosyl-oligosaccharide glucosidase
MSN moesin
MUC13 mucin 13, cell surface associated
MX1 MX dynamin-like GTPase 1
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
MYO1A myosin IA
MYO1D myosin ID
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NACA nascent polypeptide-associated complex alpha subunit
NCEH1 neutral cholesterol ester hydrolase 1
NCSTN nicastrin
NEO1 neogenin 1
NOMO1 NODAL modulator 1
NPC1 Niemann-Pick disease, type C1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NT5E 5'-nucleotidase, ecto (CD73)
NUP210 nucleoporin 210kDa
P3H1 prolyl 3-hydroxylase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HB prolyl 4-hydroxylase, beta polypeptide
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PCYOX1 prenylcysteine oxidase 1
PDCD10 programmed cell death 10
PDIA3 protein disulfide isomerase family A, member 3
PDIA6 protein disulfide isomerase family A, member 6
PHACTR4 phosphatase and actin regulator 4
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PIGR polymeric immunoglobulin receptor
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIP prolactin-induced protein
PITPNB phosphatidylinositol transfer protein, beta
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEC plectin
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLXNB2 plexin B2
PODXL2 podocalyxin-like 2
PPT1 palmitoyl-protein thioesterase 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PRRC1 proline-rich coiled-coil 1
PSAP prosaposin
PTGES2 prostaglandin E synthase 2
PTGFRN prostaglandin F2 receptor inhibitor
PTTG1IP pituitary tumor-transforming 1 interacting protein
RAB11A RAB11A, member RAS oncogene family
RAB12 RAB12, member RAS oncogene family
RAB14 RAB14, member RAS oncogene family
RAB15 RAB15, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB21 RAB21, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RABIF RAB interacting factor
RABL6 RAB, member RAS oncogene family-like 6
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RALB v-ral simian leukemia viral oncogene homolog B
RANGAP1 Ran GTPase activating protein 1
RAP1A RAP1A, member of RAS oncogene family
RDX radixin
RELN reelin
RHOB ras homolog family member B
RHOC ras homolog family member C
RHOG ras homolog family member G
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
RRAS related RAS viral (r-ras) oncogene homolog
RSU1 Ras suppressor protein 1
SAMHD1 SAM domain and HD domain 1
SARNP SAP domain containing ribonucleoprotein
SCARB1 scavenger receptor class B, member 1
SCARB2 scavenger receptor class B, member 2
SDCBP syndecan binding protein (syntenin)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEPT11 septin 11
SEPT2 septin 2
SEPT7 septin 7
SEPT9 septin 9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SETD3 SET domain containing 3
SGSH N-sulfoglucosamine sulfohydrolase
SIAE sialic acid acetylesterase
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLK STE20-like kinase
SNX2 sorting nexin 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP54 signal recognition particle 54kDa
SRP68 signal recognition particle 68kDa
SRP72 signal recognition particle 72kDa
SSR1 signal sequence receptor, alpha
SSRP1 structure specific recognition protein 1
STOM stomatin
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STX3 syntaxin 3
SUMF1 sulfatase modifying factor 1
SUN2 Sad1 and UNC84 domain containing 2
SYNGR2 synaptogyrin 2
TFRC transferrin receptor
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMX3 thioredoxin-related transmembrane protein 3
TOMM34 translocase of outer mitochondrial membrane 34
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TPBG trophoblast glycoprotein
TPD52 tumor protein D52
TPP1 tripeptidyl peptidase I
TRAPPC3 trafficking protein particle complex 3
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM28 tripartite motif containing 28
TSPAN4 tetraspanin 4
TSPAN7 tetraspanin 7
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TUBB tubulin, beta class I
TUBB4A tubulin, beta 4A class IVa
TXNDC15 thioredoxin domain containing 15
UBC ubiquitin C
UBQLN2 ubiquilin 2
VLDLR very low density lipoprotein receptor
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VSNL1 visinin-like 1