ITGA6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description integrin, alpha 6|The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3655)
External Link https://ncbi.nlm.nih.gov/gene/3655
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Genes

499 genes differentially expressed following the ITGA6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 0.0158868
PROM1 prominin 1 0.015434
APOD apolipoprotein D 0.0139283
MAP7 microtubule-associated protein 7 0.0134343
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.0131604
C3 complement component 3 0.0131225
CCL19 chemokine (C-C motif) ligand 19 0.013022
SPARCL1 SPARC-like 1 (hevin) 0.0126339
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.0121767
CHN2 chimerin 2 0.0119705
CP ceruloplasmin (ferroxidase) 0.0116394
KYNU kynureninase 0.011293
SSBP2 single-stranded DNA binding protein 2 0.0111707
JPT2 Jupiter microtubule associated homolog 2 0.0109522
C1S complement component 1, s subcomponent 0.0107858
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0107068
SEPP1 selenoprotein P, plasma, 1 0.0106725
TSPAN13 tetraspanin 13 0.0106469
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0104838
LTF lactotransferrin 0.010238
TGFBI transforming growth factor, beta-induced, 68kDa 0.0101997
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0100589
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0100391
PPAP2A phosphatidic acid phosphatase type 2A 0.00998959
TPPP3 tubulin polymerization-promoting protein family member 3 0.0099756
MCOLN1 mucolipin 1 0.00997541
MGP matrix Gla protein 0.00992507
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00991649
FGF13 fibroblast growth factor 13 0.00977534
ANOS1 anosmin 1 0.00943002
CXCL13 chemokine (C-X-C motif) ligand 13 0.00933352
SDC2 syndecan 2 0.00928291
COL15A1 collagen, type XV, alpha 1 0.0091915
IFI44L interferon-induced protein 44-like 0.00916968
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00906165
EPCAM epithelial cell adhesion molecule 0.00904318
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00901811
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.008725
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00862203
A2M alpha-2-macroglobulin 0.00860295
STOM stomatin 0.00855727
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00851639
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00850975
CH25H cholesterol 25-hydroxylase 0.00850733
KRT19 keratin 19, type I 0.0083641
FUCA1 fucosidase, alpha-L- 1, tissue 0.00836263
IRF8 interferon regulatory factor 8 0.00836231
CXCL14 chemokine (C-X-C motif) ligand 14 0.00833236
FABP4 fatty acid binding protein 4, adipocyte 0.00830942
IL13RA2 interleukin 13 receptor, alpha 2 0.00829131
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00826882
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00826004
TXN thioredoxin 0.00822321
FZD6 frizzled class receptor 6 0.00821808
SELL selectin L 0.00820814
TSPAN7 tetraspanin 7 0.00820275
ELOVL5 ELOVL fatty acid elongase 5 0.00816912
HOPX HOP homeobox 0.00808042
C8ORF4 chromosome 8 open reading frame 4 0.00801302
CTSC cathepsin C 0.00794452
ANGPT1 angiopoietin 1 0.00794087
LPXN leupaxin 0.00788187
TCTA T-cell leukemia translocation altered 0.00787176
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00786282
MTUS1 microtubule associated tumor suppressor 1 0.0078615
ADGRF5 adhesion G protein-coupled receptor F5 0.00784774
IL6 interleukin 6 0.00783345
EGR1 early growth response 1 0.00781754
RTN1 reticulon 1 0.00778667
PDLIM3 PDZ and LIM domain 3 0.00776321
CCL14 chemokine (C-C motif) ligand 14 0.00774718
RHOBTB3 Rho-related BTB domain containing 3 0.00771026
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.007601
WWOX WW domain containing oxidoreductase 0.00759162
CCNA2 cyclin A2 0.00759071
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00756338
ZDHHC6 zinc finger, DHHC-type containing 6 0.00755014
CXCL9 chemokine (C-X-C motif) ligand 9 0.0074721
AQP1 aquaporin 1 (Colton blood group) 0.00746322
ISG20 interferon stimulated exonuclease gene 20kDa 0.00744126
STK17A serine/threonine kinase 17a 0.00740347
RAD23B RAD23 homolog B (S. cerevisiae) 0.00740002
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00739205
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00737599
RHOH ras homolog family member H 0.00730618
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.00728479
DUSP10 dual specificity phosphatase 10 0.00727483
MAOA monoamine oxidase A 0.00726115
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.00723384
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00723205
CXCL10 chemokine (C-X-C motif) ligand 10 0.00720617
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00720483
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00720338
LY86 lymphocyte antigen 86 0.00717996
TSPAN1 tetraspanin 1 0.00717467
CXADR coxsackie virus and adenovirus receptor 0.0071715
TMEM176B transmembrane protein 176B 0.00715391
LMO2 LIM domain only 2 (rhombotin-like 1) 0.007144
SPRED2 sprouty-related, EVH1 domain containing 2 0.00712592
IQCG IQ motif containing G 0.00711849
VLDLR very low density lipoprotein receptor 0.00711414
ERGIC2 ERGIC and golgi 2 0.00709708
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00709566
CD36 CD36 molecule (thrombospondin receptor) 0.00708816
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00692455
ITM2A integral membrane protein 2A 0.00692267
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00687162
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00682611
CCL8 chemokine (C-C motif) ligand 8 0.00674705
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00673627
SASH1 SAM and SH3 domain containing 1 0.00673525
MGLL monoglyceride lipase 0.00671473
UPK1B uroplakin 1B 0.0067112
DCLK1 doublecortin-like kinase 1 0.00670893
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00669976
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00669639
CST6 cystatin E/M 0.00665969
TGM2 transglutaminase 2 0.00664531
C7 complement component 7 0.00662864
IFI44 interferon-induced protein 44 0.00655751
PIP prolactin-induced protein 0.00654984
EXPH5 exophilin 5 0.00654714
S100P S100 calcium binding protein P 0.00650991
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.00649267
PON3 paraoxonase 3 0.00647638
FNBP1 formin binding protein 1 0.00643603
COL21A1 collagen, type XXI, alpha 1 0.00642256
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00640268
HBB hemoglobin, beta 0.00638378
TM2D1 TM2 domain containing 1 0.0063749
ASF1A anti-silencing function 1A histone chaperone 0.00636406
PRKD3 protein kinase D3 0.00635123
THBD thrombomodulin 0.00635015
LGALS13 lectin, galactoside-binding, soluble, 13 0.00626657
CD34 CD34 molecule 0.00626394
PRDX4 peroxiredoxin 4 0.00624975
CCDC176 coiled-coil domain containing 176 0.00623415
NXT2 nuclear transport factor 2-like export factor 2 0.0062276
GNAS GNAS complex locus 0.00622131
CHN1 chimerin 1 0.00622074
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00619878
AKR1C2 aldo-keto reductase family 1, member C2 0.00619086
TUBB2A tubulin, beta 2A class IIa 0.00617086
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00616205
H1-2 H1.2 linker histone, cluster member 0.0061372
CLN5 ceroid-lipofuscinosis, neuronal 5 0.00613174
RET ret proto-oncogene 0.00612249
SELENOF selenoprotein F 0.00610854
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00604867
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00604702
CSTA cystatin A (stefin A) 0.006046
RFTN1 raftlin, lipid raft linker 1 0.00603616
RNFT1 ring finger protein, transmembrane 1 0.00602566
CTSH cathepsin H 0.00602061
MED21 mediator complex subunit 21 0.00601705
SORD sorbitol dehydrogenase 0.00601202
LAMP3 lysosomal-associated membrane protein 3 0.00600115
CD93 CD93 molecule 0.00599837
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00597808
DAAM1 dishevelled associated activator of morphogenesis 1 0.00596098
RGS16 regulator of G-protein signaling 16 0.00595969
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00593758
MCAM melanoma cell adhesion molecule 0.00591351
CETN2 centrin, EF-hand protein, 2 0.00587185
AOX1 aldehyde oxidase 1 0.00586734
CD59 CD59 molecule, complement regulatory protein 0.00585535
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.00584997
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00583405
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00582233
ACTG2 actin, gamma 2, smooth muscle, enteric 0.0058221
TMEM230 transmembrane protein 230 0.0058075
KLF6 Kruppel-like factor 6 0.00580149
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00579616
MT1M metallothionein 1M 0.00577233
WASL Wiskott-Aldrich syndrome-like 0.00577023
MX1 MX dynamin-like GTPase 1 0.00576978
COL4A2 collagen, type IV, alpha 2 0.00576874
CD53 CD53 molecule 0.00574373
CXCR4 chemokine (C-X-C motif) receptor 4 0.0057409
TSC22D1 TSC22 domain family, member 1 0.00573068
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00572783
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00572283
SINHCAF SIN3-HDAC complex associated factor 0.00572232
GLRX glutaredoxin (thioltransferase) 0.00570281
S100B S100 calcium binding protein B 0.00569827
SPAG6 sperm associated antigen 6 0.0056725
EFHD1 EF-hand domain family, member D1 0.00567081
TXNIP thioredoxin interacting protein 0.00566867
COMMD10 COMM domain containing 10 0.00566293
CHI3L2 chitinase 3-like 2 0.00565294
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.00564258
CD99 CD99 molecule 0.00562663
MMP7 matrix metallopeptidase 7 0.0056263
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.00562488
SCAMP1 secretory carrier membrane protein 1 0.00562246
COPS7A COP9 signalosome subunit 7A 0.0056223
EHF ets homologous factor 0.00561239
APOLD1 apolipoprotein L domain containing 1 0.0056059
EGR2 early growth response 2 0.0056031
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00559146
NCK1 NCK adaptor protein 1 0.0055894
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00557457
C1R complement component 1, r subcomponent 0.00556646
C1QA complement component 1, q subcomponent, A chain 0.00556121
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.005558
REEP1 receptor accessory protein 1 0.0055573
STK38L serine/threonine kinase 38 like 0.00555632
GCH1 GTP cyclohydrolase 1 0.00555426
DCK deoxycytidine kinase 0.00555219
AMACR alpha-methylacyl-CoA racemase 0.00554884
INSM1 insulinoma-associated 1 0.00554824
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 0.00553805
LAMC2 laminin, gamma 2 0.00553551
RHOA ras homolog family member A 0.0055267
SRPX sushi-repeat containing protein, X-linked 0.00550407
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.00549871
YIPF6 Yip1 domain family, member 6 0.00549332
C1QTNF3 C1q and tumor necrosis factor related protein 3 0.00549054
PCSK6 proprotein convertase subtilisin/kexin type 6 0.00548977
BCHE butyrylcholinesterase 0.00548854
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00548497
BAG2 BCL2-associated athanogene 2 0.00547859
SLC35A5 solute carrier family 35, member A5 0.00547308
KLF4 Kruppel-like factor 4 (gut) 0.00546955
GPM6B glycoprotein M6B 0.00546462
SMYD2 SET and MYND domain containing 2 0.00546158
CHRDL1 chordin-like 1 0.00544606
NOP10 NOP10 ribonucleoprotein 0.00542755
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.00542349
ELL2 elongation factor, RNA polymerase II, 2 0.00542145
AKAP12 A kinase (PRKA) anchor protein 12 0.0054212
ARHGAP29 Rho GTPase activating protein 29 0.00541191
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00540675
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00540133
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00538252
WFDC2 WAP four-disulfide core domain 2 0.00537807
TMEM100 transmembrane protein 100 0.00536929
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 0.00536796
TSPAN6 tetraspanin 6 0.00535396
NFIB nuclear factor I/B 0.00534893
HCP5 HLA complex P5 (non-protein coding) 0.00534039
GIMAP6 GTPase, IMAP family member 6 0.00533626
ATG5 autophagy related 5 0.00532755
DES desmin 0.00532431
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.00531039
CD83 CD83 molecule 0.00530251
HMBOX1 homeobox containing 1 0.00527953
FRS2 fibroblast growth factor receptor substrate 2 0.00527772
SPTBN1 spectrin, beta, non-erythrocytic 1 0.00527222
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00526995

decreased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.014827
STC2 stanniocalcin 2 -0.0131305
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0123639
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0115207
TNNT1 troponin T type 1 (skeletal, slow) -0.0113679
FST follistatin -0.0103054
LYPD1 LY6/PLAUR domain containing 1 -0.0102469
SIRT3 sirtuin 3 -0.00979266
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.009778
TXLNA taxilin alpha -0.0094235
HTRA1 HtrA serine peptidase 1 -0.00940856
MDK midkine (neurite growth-promoting factor 2) -0.00929218
P3H2 prolyl 3-hydroxylase 2 -0.00920261
LTBP2 latent transforming growth factor beta binding protein 2 -0.00901153
PFKL phosphofructokinase, liver -0.0089228
AUTS2 autism susceptibility candidate 2 -0.00848146
PRKCA protein kinase C, alpha -0.00840532
EIF5A eukaryotic translation initiation factor 5A -0.00838348
PDZK1IP1 PDZK1 interacting protein 1 -0.00835882
TSPO translocator protein (18kDa) -0.00833488
ZNF91 zinc finger protein 91 -0.00821083
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00807973
CBS cystathionine-beta-synthase -0.00802477
PKM pyruvate kinase, muscle -0.00780934
ACAT2 acetyl-CoA acetyltransferase 2 -0.00779047
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00773533
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00771501
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00769987
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00764998
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00759504
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00757672
VNN1 vanin 1 -0.00753705
TGFB1 transforming growth factor, beta 1 -0.00753295
NTS neurotensin -0.00745202
NBEAL2 neurobeachin-like 2 -0.00736933
JCHAIN joining chain of multimeric IgA and IgM -0.00727887
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00727818
ADD3 adducin 3 (gamma) -0.00726365
TECR trans-2,3-enoyl-CoA reductase -0.00723978
AMPD2 adenosine monophosphate deaminase 2 -0.0072019
BMP2 bone morphogenetic protein 2 -0.00711333
LRRC15 leucine rich repeat containing 15 -0.00710517
MGAM maltase-glucoamylase -0.00707101
DACH1 dachshund family transcription factor 1 -0.00706766
IL7R interleukin 7 receptor -0.00705105
PLBD1 phospholipase B domain containing 1 -0.00703098
SULF1 sulfatase 1 -0.00698731
GOLGA8A golgin A8 family, member A -0.00698466
GMPR guanosine monophosphate reductase -0.00697541
CALB1 calbindin 1, 28kDa -0.00693468
FOLR1 folate receptor 1 (adult) -0.00691792
TNIK TRAF2 and NCK interacting kinase -0.00678292
NOTCH1 notch 1 -0.00673159
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00671401
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.00665995
ZNF721 zinc finger protein 721 -0.00664356
SPRR3 small proline-rich protein 3 -0.00663163
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00659436
ATP5F1D ATP synthase F1 subunit delta -0.00659136
ZNF160 zinc finger protein 160 -0.00655097
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.00654796
CYBA cytochrome b-245, alpha polypeptide -0.00654667
KLK11 kallikrein-related peptidase 11 -0.00654555
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00651582
ESR1 estrogen receptor 1 -0.00649785
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00646861
SST somatostatin -0.00644992
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00643889
DUOX2 dual oxidase 2 -0.00640222
PTPRE protein tyrosine phosphatase, receptor type, E -0.00638419
HAS2 hyaluronan synthase 2 -0.00634607
RGS4 regulator of G-protein signaling 4 -0.00631434
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -0.00628708
CTSZ cathepsin Z -0.00623499
MINK1 misshapen-like kinase 1 -0.00620545
FBP1 fructose-1,6-bisphosphatase 1 -0.00618335
NCOA2 nuclear receptor coactivator 2 -0.00615413
TPM2 tropomyosin 2 (beta) -0.00613675
CA12 carbonic anhydrase XII -0.00612666
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -0.00612661
MPRIP myosin phosphatase Rho interacting protein -0.00610732
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -0.00608355
KLHL21 kelch-like family member 21 -0.00607913
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.0060777
SGSM2 small G protein signaling modulator 2 -0.00606707
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00606243
TPSAB1 tryptase alpha/beta 1 -0.00603988
ANKRD11 ankyrin repeat domain 11 -0.00603122
ANO3 anoctamin 3 -0.00601454
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -0.00601338
PRDX2 peroxiredoxin 2 -0.00600812
XIC X chromosome inactivation center -0.005994
PENK proenkephalin -0.00599103
PITX2 paired-like homeodomain 2 -0.00598994
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00598409
PRKCI protein kinase C, iota -0.00595607
DGAT1 diacylglycerol O-acyltransferase 1 -0.00594045
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -0.00593667
NAV2 neuron navigator 2 -0.00591278
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0058903
ACADVL acyl-CoA dehydrogenase, very long chain -0.00588324
PITX3 paired-like homeodomain 3 -0.00588049
PRPF8 pre-mRNA processing factor 8 -0.00585318
SCRIB scribbled planar cell polarity protein -0.00582433
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00582081
BCR breakpoint cluster region -0.00582011
PNMA2 paraneoplastic Ma antigen 2 -0.00580474
CHD7 chromodomain helicase DNA binding protein 7 -0.00577899
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00574256
PITX1 paired-like homeodomain 1 -0.00573929
CLC Charcot-Leyden crystal galectin -0.00572578
SPATA20 spermatogenesis associated 20 -0.00568112
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00567052
CCNF cyclin F -0.00566089
HAUS2 HAUS augmin-like complex, subunit 2 -0.00565204
COL9A2 collagen, type IX, alpha 2 -0.00565149
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00564462
MNDA myeloid cell nuclear differentiation antigen -0.00563842
TFF2 trefoil factor 2 -0.00563579
LRRC17 leucine rich repeat containing 17 -0.00563262
DGKZ diacylglycerol kinase, zeta -0.00562944
FGFR3 fibroblast growth factor receptor 3 -0.0056273
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00560546
MMP12 matrix metallopeptidase 12 -0.00558992
BASP1 brain abundant, membrane attached signal protein 1 -0.00558689
ZBTB7A zinc finger and BTB domain containing 7A -0.00558411
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00557559
NRGN neurogranin (protein kinase C substrate, RC3) -0.00557469
IFITM2 interferon induced transmembrane protein 2 -0.00555608
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00555491
CRP C-reactive protein, pentraxin-related -0.00554867
GSTM3 glutathione S-transferase mu 3 (brain) -0.00551885
PLAUR plasminogen activator, urokinase receptor -0.00551455
PHGDH phosphoglycerate dehydrogenase -0.00551274
KLK12 kallikrein-related peptidase 12 -0.00550668
PRRC2A proline-rich coiled-coil 2A -0.00550445
C2CD2 C2 calcium-dependent domain containing 2 -0.00549931
NELL2 NEL-like 2 (chicken) -0.00549301
IRX5 iroquois homeobox 5 -0.00546076
PUF60 poly-U binding splicing factor 60KDa -0.00545325
PF4 platelet factor 4 -0.00545203
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -0.00544905
CBX7 chromobox homolog 7 -0.00544181
CSF3R colony stimulating factor 3 receptor (granulocyte) -0.00542351
TALDO1 transaldolase 1 -0.00541591
EFNB3 ephrin-B3 -0.00541527
CLIC3 chloride intracellular channel 3 -0.00536838
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -0.0053423
MCM7 minichromosome maintenance complex component 7 -0.00534026
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.00533799
NADSYN1 NAD synthetase 1 -0.00533576
KLK10 kallikrein-related peptidase 10 -0.00532409
GLOD4 glyoxalase domain containing 4 -0.00530991
PRKCSH protein kinase C substrate 80K-H -0.0052749
ATG2A autophagy related 2A -0.00522686
NANOG Nanog homeobox -0.00521482
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00520429
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.00520417
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00520005
MAN2C1 mannosidase, alpha, class 2C, member 1 -0.00519768
AOC1 amine oxidase, copper containing 1 -0.00518294
HEPH hephaestin -0.00518105
GARS1 glycyl-tRNA synthetase 1 -0.0051478
HSF1 heat shock transcription factor 1 -0.00514039
MAMLD1 mastermind-like domain containing 1 -0.00513872
PRR11 proline rich 11 -0.00512606
CYBB cytochrome b-245, beta polypeptide -0.00512504
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00512094
PI3 peptidase inhibitor 3, skin-derived -0.00511921
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -0.00511915
AKAP8 A kinase (PRKA) anchor protein 8 -0.00508737
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta -0.00508644
GCN1 GCN1 activator of EIF2AK4 -0.00508638
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.00507654
FGG fibrinogen gamma chain -0.00506912
GSTA1 glutathione S-transferase alpha 1 -0.00506284
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.00506194
TBL1X transducin (beta)-like 1X-linked -0.00506038
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00505793
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.00505381
IFRD1 interferon-related developmental regulator 1 -0.00505059
RAP2B RAP2B, member of RAS oncogene family -0.00504323
ADAM12 ADAM metallopeptidase domain 12 -0.00504059
GLDC glycine dehydrogenase (decarboxylating) -0.00503913
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -0.00503335
CRCT1 cysteine-rich C-terminal 1 -0.00503287
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00503152
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00503073
AAMDC adipogenesis associated, Mth938 domain containing -0.00502651
PMM2 phosphomannomutase 2 -0.00501595
ANXA6 annexin A6 -0.00499608
WDR6 WD repeat domain 6 -0.00499569
ELANE elastase, neutrophil expressed -0.00498954
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.00498601
CLEC11A C-type lectin domain family 11, member A -0.0049783
PDE4A phosphodiesterase 4A, cAMP-specific -0.004973
DVL3 dishevelled segment polarity protein 3 -0.00496114
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.0049481
PITPNA phosphatidylinositol transfer protein, alpha -0.0049462
MAST3 microtubule associated serine/threonine kinase 3 -0.0049409
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.00492966
LMNB2 lamin B2 -0.00492876
EPS8L1 EPS8-like 1 -0.00492793
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -0.00492341
RAP2A RAP2A, member of RAS oncogene family -0.00491816
GPX4 glutathione peroxidase 4 -0.00490648
PLXNB1 plexin B1 -0.00489975
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -0.00488924
GTF2IRD1 GTF2I repeat domain containing 1 -0.00488518
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.00488378
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -0.0048801
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00487943
WNT5A wingless-type MMTV integration site family, member 5A -0.00487646
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.00486776
CARD10 caspase recruitment domain family, member 10 -0.00484994
AZU1 azurocidin 1 -0.00484823
HAL histidine ammonia-lyase -0.00484664
RASA4 RAS p21 protein activator 4 -0.00484508
MFAP3L microfibrillar-associated protein 3-like -0.00482815
NOD2 nucleotide-binding oligomerization domain containing 2 -0.00482433
FBXW12 F-box and WD repeat domain containing 12 -0.00482302
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -0.00482265
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00481515
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00479517
TRIM28 tripartite motif containing 28 -0.00478613
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -0.00478065
KMT2B lysine (K)-specific methyltransferase 2B -0.0047738
H1-0 H1.0 linker histone -0.00477217
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00477131
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00475666
DENND5A DENN/MADD domain containing 5A -0.00474333
UPP1 uridine phosphorylase 1 -0.00474276
PFKM phosphofructokinase, muscle -0.00472995
AURKB aurora kinase B -0.00472742
FZD2 frizzled class receptor 2 -0.00472618
HMGA1 high mobility group AT-hook 1 -0.00472283
LTBP4 latent transforming growth factor beta binding protein 4 -0.00470884
NR2F6 nuclear receptor subfamily 2, group F, member 6 -0.00470719
COPG1 coatomer protein complex, subunit gamma 1 -0.00470606
EFHD2 EF-hand domain family, member D2 -0.0047028
FKBP11 FK506 binding protein 11, 19 kDa -0.00469522
PCNT pericentrin -0.00468482
CORO1C coronin, actin binding protein, 1C -0.00468377
OLFM4 olfactomedin 4 -0.0046823
IL17RA interleukin 17 receptor A -0.00467919
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00467608
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -0.00467321
FAM86B1 family with sequence similarity 86, member B1 -0.00465938
ALDOA aldolase A, fructose-bisphosphate -0.0046467