| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | integrin, alpha 8|Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 8516) |
| External Link | https://ncbi.nlm.nih.gov/gene/8516 |
| Similar Terms | |
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499 genes differentially expressed following the ITGA8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.0228723 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.0166933 |
| RNF167 | ring finger protein 167 | 0.0166534 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0164986 |
| S100A9 | S100 calcium binding protein A9 | 0.0157664 |
| S100A8 | S100 calcium binding protein A8 | 0.0148464 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0146233 |
| RRAGA | Ras-related GTP binding A | 0.0143147 |
| NIBAN1 | niban apoptosis regulator 1 | 0.014306 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.0142619 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.0126875 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0126435 |
| PLIN2 | perilipin 2 | 0.0124655 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.0122829 |
| LTF | lactotransferrin | 0.0122312 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0121527 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0120893 |
| MAGEA3 | melanoma antigen family A3 | 0.0117812 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.0112537 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0110307 |
| CP | ceruloplasmin (ferroxidase) | 0.0109696 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.0107382 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.0106589 |
| FLNA | filamin A, alpha | 0.0106183 |
| PLBD1 | phospholipase B domain containing 1 | 0.0103496 |
| KYNU | kynureninase | 0.0102782 |
| CST3 | cystatin C | 0.0102619 |
| S100A7 | S100 calcium binding protein A7 | 0.0102122 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.0102043 |
| WT1 | Wilms tumor 1 | 0.0101577 |
| TMEM45A | transmembrane protein 45A | 0.010026 |
| TRIB2 | tribbles pseudokinase 2 | 0.0100222 |
| FGL2 | fibrinogen-like 2 | 0.00975478 |
| PLXNC1 | plexin C1 | 0.00965908 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00960598 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00953024 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00949102 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00948496 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00945364 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00940471 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0093971 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00934635 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00933413 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00928912 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00927244 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00920812 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00915353 |
| H1-0 | H1.0 linker histone | 0.00908638 |
| BLVRB | biliverdin reductase B | 0.00902394 |
| LSP1 | lymphocyte-specific protein 1 | 0.0089536 |
| ACTN4 | actinin, alpha 4 | 0.00882405 |
| CTSD | cathepsin D | 0.00882072 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.00877124 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0086825 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00860749 |
| C5AR1 | complement component 5a receptor 1 | 0.00860516 |
| CFI | complement factor I | 0.00858868 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00857233 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.0085275 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00851816 |
| ACTN1 | actinin, alpha 1 | 0.00850626 |
| NID1 | nidogen 1 | 0.00849154 |
| C1R | complement component 1, r subcomponent | 0.00843095 |
| EMP3 | epithelial membrane protein 3 | 0.00838347 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00837403 |
| VCL | vinculin | 0.0083414 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00832795 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00832309 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00829953 |
| GPR65 | G protein-coupled receptor 65 | 0.0082807 |
| MMP7 | matrix metallopeptidase 7 | 0.00826968 |
| IFI44 | interferon-induced protein 44 | 0.00825704 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00822176 |
| CD300A | CD300a molecule | 0.00820281 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00817427 |
| NUCB1 | nucleobindin 1 | 0.00816768 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00811615 |
| STXBP2 | syntaxin binding protein 2 | 0.00808679 |
| FOLR1 | folate receptor 1 (adult) | 0.00808457 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00804344 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00801772 |
| TGFB1 | transforming growth factor, beta 1 | 0.00801701 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00800008 |
| NCF2 | neutrophil cytosolic factor 2 | 0.0079973 |
| HBD | hemoglobin, delta | 0.00799711 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.007986 |
| TLN1 | talin 1 | 0.00795259 |
| BEX4 | brain expressed, X-linked 4 | 0.00791992 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00791554 |
| CDC20 | cell division cycle 20 | 0.00791021 |
| PLK2 | polo-like kinase 2 | 0.00790843 |
| CFB | complement factor B | 0.0078843 |
| GANAB | glucosidase, alpha; neutral AB | 0.00783233 |
| METRN | meteorin, glial cell differentiation regulator | 0.00781244 |
| KAZN | kazrin, periplakin interacting protein | 0.00780917 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00776673 |
| PKM | pyruvate kinase, muscle | 0.0076553 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00765187 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00764396 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00760993 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.00759618 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00758236 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00757498 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00757247 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.00754597 |
| TLR1 | toll-like receptor 1 | 0.00752132 |
| MINK1 | misshapen-like kinase 1 | 0.00751884 |
| BCHE | butyrylcholinesterase | 0.00750993 |
| CLGN | calmegin | 0.00746666 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.00744015 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | 0.00743557 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00738277 |
| TPBG | trophoblast glycoprotein | 0.00737308 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00734252 |
| AK4 | adenylate kinase 4 | 0.00731406 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00729841 |
| GAS1 | growth arrest-specific 1 | 0.00727749 |
| FBXO9 | F-box protein 9 | 0.00727591 |
| IFI44L | interferon-induced protein 44-like | 0.00726831 |
| PLXNB2 | plexin B2 | 0.00725275 |
| PRAME | preferentially expressed antigen in melanoma | 0.00724786 |
| NFE2 | nuclear factor, erythroid 2 | 0.00722684 |
| ARRB2 | arrestin, beta 2 | 0.00721144 |
| XAF1 | XIAP associated factor 1 | 0.00720931 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00720234 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00719891 |
| NCKAP1L | NCK-associated protein 1-like | 0.00718869 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00718533 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00717701 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0071768 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | 0.0071603 |
| PITX1 | paired-like homeodomain 1 | 0.00715382 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.0071276 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00708002 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.00705367 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00702041 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00700589 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0069883 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.00698382 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.00695462 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00694721 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00693162 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00690199 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00687782 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00685354 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00684575 |
| GCH1 | GTP cyclohydrolase 1 | 0.00684535 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00683133 |
| PSAP | prosaposin | 0.00680333 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00679916 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00679856 |
| DAPK1 | death-associated protein kinase 1 | 0.00678499 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00677876 |
| ZYX | zyxin | 0.00676582 |
| PDGFC | platelet derived growth factor C | 0.00674516 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00670373 |
| TLE4 | transducin-like enhancer of split 4 | 0.00669696 |
| PDGFD | platelet derived growth factor D | 0.00669157 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00668802 |
| DGKZ | diacylglycerol kinase, zeta | 0.00668249 |
| IL32 | interleukin 32 | 0.00667472 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00662958 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 0.00662902 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00661519 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00660481 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00658895 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00658568 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00655016 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00654221 |
| TLR7 | toll-like receptor 7 | 0.00653134 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.0065265 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00651638 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00648934 |
| TLR2 | toll-like receptor 2 | 0.00647929 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | 0.00647347 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00646635 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00646107 |
| COL9A2 | collagen, type IX, alpha 2 | 0.0064593 |
| S100A12 | S100 calcium binding protein A12 | 0.00645884 |
| ADORA2B | adenosine A2b receptor | 0.00642246 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00641817 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 | 0.00641258 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00641068 |
| CD86 | CD86 molecule | 0.00640042 |
| CSAD | cysteine sulfinic acid decarboxylase | 0.00638685 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00638308 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.0063448 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00633921 |
| STK26 | serine/threonine protein kinase 26 | 0.00632891 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00632547 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00630348 |
| CTSH | cathepsin H | 0.00629702 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00628662 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.00628426 |
| AMPD2 | adenosine monophosphate deaminase 2 | 0.0062744 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00626769 |
| GPM6B | glycoprotein M6B | 0.00625848 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00625423 |
| OBSL1 | obscurin-like 1 | 0.00622887 |
| IL1RN | interleukin 1 receptor antagonist | 0.0062261 |
| CD14 | CD14 molecule | 0.00620001 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.00619964 |
| RXRA | retinoid X receptor, alpha | 0.00619897 |
| ZNF91 | zinc finger protein 91 | 0.00619575 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0061852 |
| DMXL2 | Dmx-like 2 | 0.00617987 |
| RUSF1 | RUS family member 1 | 0.00615965 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00614212 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00613741 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00613615 |
| RIN2 | Ras and Rab interactor 2 | 0.00613075 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00611756 |
| FPR1 | formyl peptide receptor 1 | 0.00609783 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00608901 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00608288 |
| MYO1F | myosin IF | 0.00607336 |
| MGAM | maltase-glucoamylase | 0.00606339 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.00605364 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00605332 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | 0.0060345 |
| CLCA2 | chloride channel accessory 2 | 0.00602931 |
| TYMS | thymidylate synthetase | 0.00601971 |
| GPC4 | glypican 4 | 0.00599047 |
| LY75 | lymphocyte antigen 75 | 0.00598923 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.00597881 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00597276 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.00596091 |
| DENND2B | DENN domain containing 2B | 0.0059557 |
| VLDLR | very low density lipoprotein receptor | 0.00594021 |
| RNF144A | ring finger protein 144A | 0.00593888 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00593455 |
| RRAGD | Ras-related GTP binding D | 0.00591306 |
| TYMP | thymidine phosphorylase | 0.00591193 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00589825 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.00589494 |
| CD70 | CD70 molecule | 0.00588062 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00587878 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00587397 |
| PFAS | phosphoribosylformylglycinamidine synthase | 0.00585164 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.00584871 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00583564 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00583395 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00582985 |
| C1RL | complement component 1, r subcomponent-like | 0.00582619 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00581614 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | 0.00578346 |
| PMP22 | peripheral myelin protein 22 | 0.00576193 |
| GPSM3 | G-protein signaling modulator 3 | 0.00575763 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00574736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0171156 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0142421 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0140286 |
| ADIRF | adipogenesis regulatory factor | -0.0127502 |
| CDCA4 | cell division cycle associated 4 | -0.0126418 |
| RGCC | regulator of cell cycle | -0.0119006 |
| MAP7 | microtubule-associated protein 7 | -0.011755 |
| WIF1 | WNT inhibitory factor 1 | -0.0115907 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0110468 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.0107968 |
| HOXC6 | homeobox C6 | -0.0107335 |
| GSN | gelsolin | -0.010472 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00989652 |
| GLA | galactosidase, alpha | -0.00934626 |
| NNMT | nicotinamide N-methyltransferase | -0.00895733 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00895718 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00883955 |
| KRT20 | keratin 20, type I | -0.00882016 |
| SFTPA2 | surfactant protein A2 | -0.00881216 |
| TXN | thioredoxin | -0.00873874 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00872577 |
| EPCAM | epithelial cell adhesion molecule | -0.00865944 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00861709 |
| GPX2 | glutathione peroxidase 2 | -0.00845913 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00839443 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00838544 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00834654 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00819752 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00817438 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00815712 |
| CD9 | CD9 molecule | -0.00813826 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00812002 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00798001 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00791944 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00786398 |
| GLUD2 | glutamate dehydrogenase 2 | -0.00783975 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0078327 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00778167 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00777093 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00768827 |
| S100A10 | S100 calcium binding protein A10 | -0.00764041 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00754224 |
| SFTPB | surfactant protein B | -0.00749808 |
| NEBL | nebulette | -0.00747657 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.00747633 |
| TGM2 | transglutaminase 2 | -0.00738897 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00736299 |
| ESRP2 | epithelial splicing regulatory protein 2 | -0.00732281 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00728228 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00723326 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00717248 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00710339 |
| OCA2 | oculocutaneous albinism II | -0.00710325 |
| BEX1 | brain expressed, X-linked 1 | -0.00709889 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00709852 |
| MZT2A | mitotic spindle organizing protein 2A | -0.00708867 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00705185 |
| CHGB | chromogranin B | -0.00702356 |
| RPS17 | ribosomal protein S17 | -0.00698968 |
| KLF6 | Kruppel-like factor 6 | -0.00697132 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.0069645 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00694364 |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 | -0.00689083 |
| EXOC5 | exocyst complex component 5 | -0.00688346 |
| WASHC4 | WASH complex subunit 4 | -0.006834 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00682592 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00682289 |
| RAB23 | RAB23, member RAS oncogene family | -0.00681333 |
| ELN | elastin | -0.00679659 |
| STMN2 | stathmin 2 | -0.00679462 |
| MYO1B | myosin IB | -0.00677687 |
| CES1 | carboxylesterase 1 | -0.0067554 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00673992 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00667214 |
| ADK | adenosine kinase | -0.00667173 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.00664355 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00657684 |
| AVPI1 | arginine vasopressin-induced 1 | -0.00656122 |
| MAOA | monoamine oxidase A | -0.00655792 |
| TRAPPC2L | trafficking protein particle complex 2-like | -0.00651348 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.0065087 |
| TSPAN1 | tetraspanin 1 | -0.00650648 |
| FERMT1 | fermitin family member 1 | -0.00647642 |
| INHBA | inhibin, beta A | -0.00646287 |
| TMEM110 | transmembrane protein 110 | -0.00645242 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00644669 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | -0.00641088 |
| AGO2 | argonaute RISC catalytic component 2 | -0.00637011 |
| SMS | spermine synthase | -0.00634991 |
| EPN2 | epsin 2 | -0.00634895 |
| MBD1 | methyl-CpG binding domain protein 1 | -0.00634356 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.0063242 |
| MMP12 | matrix metallopeptidase 12 | -0.00631044 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.0063077 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00629843 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0062781 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.00627676 |
| RGS10 | regulator of G-protein signaling 10 | -0.00625502 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0062521 |
| OGA | O-GlcNAcase | -0.00623071 |
| KCTD20 | potassium channel tetramerization domain containing 20 | -0.00618367 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00616965 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00613857 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.00612563 |
| SPRR3 | small proline-rich protein 3 | -0.00609618 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00608985 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00607751 |
| EMP2 | epithelial membrane protein 2 | -0.00606649 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00605938 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00604733 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00604453 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00604148 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.0060026 |
| NUP85 | nucleoporin 85kDa | -0.00599463 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00598835 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00598752 |
| ATP9A | ATPase, class II, type 9A | -0.00598163 |
| MUC4 | mucin 4, cell surface associated | -0.00596814 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00596474 |
| MT1M | metallothionein 1M | -0.00591425 |
| TRIM8 | tripartite motif containing 8 | -0.00591174 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.00590006 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00589852 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -0.00585234 |
| MT1E | metallothionein 1E | -0.00584647 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00584381 |
| NTM | neurotrimin | -0.00583242 |
| CCNB2 | cyclin B2 | -0.00583239 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00582907 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00582059 |
| IL6ST | interleukin 6 signal transducer | -0.00581546 |
| MT1F | metallothionein 1F | -0.00578879 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.00578622 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -0.00577198 |
| LPXN | leupaxin | -0.00576726 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.00574623 |
| RPL36 | ribosomal protein L36 | -0.00573706 |
| CCN2 | cellular communication network factor 2 | -0.00572995 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.00572537 |
| TGIF1 | TGFB-induced factor homeobox 1 | -0.00571638 |
| TRAM1 | translocation associated membrane protein 1 | -0.00571613 |
| TG | thyroglobulin | -0.00571496 |
| RPA3 | replication protein A3, 14kDa | -0.00569602 |
| GLUD1 | glutamate dehydrogenase 1 | -0.00568612 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.00568239 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00566924 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | -0.00566088 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00565816 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00565053 |
| PFDN4 | prefoldin subunit 4 | -0.00563439 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | -0.0056327 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00562149 |
| SDC2 | syndecan 2 | -0.00562028 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00561666 |
| RPS27L | ribosomal protein S27-like | -0.00560358 |
| FAIM | Fas apoptotic inhibitory molecule | -0.0056003 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00559805 |
| CA4 | carbonic anhydrase IV | -0.00557419 |
| SEPTIN10 | septin 10 | -0.00557312 |
| SNX13 | sorting nexin 13 | -0.00555927 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00555781 |
| STK39 | serine threonine kinase 39 | -0.00555361 |
| SFTPC | surfactant protein C | -0.00554039 |
| PBK | PDZ binding kinase | -0.00553398 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.00552825 |
| NCAN | neurocan | -0.0055279 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00552726 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00552692 |
| DCLRE1C | DNA cross-link repair 1C | -0.00551804 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00551516 |
| STX7 | syntaxin 7 | -0.00550659 |
| FGL1 | fibrinogen-like 1 | -0.00549949 |
| CD1B | CD1b molecule | -0.00549637 |
| RAB25 | RAB25, member RAS oncogene family | -0.00549216 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.00547695 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.00547279 |
| MOB4 | MOB family member 4, phocein | -0.00546951 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.00545756 |
| GLOD4 | glyoxalase domain containing 4 | -0.00545542 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | -0.00544684 |
| NFASC | neurofascin | -0.00544672 |
| HEBP2 | heme binding protein 2 | -0.00544119 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.00543554 |
| WASHC3 | WASH complex subunit 3 | -0.00541841 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | -0.00541801 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.00541651 |
| CH25H | cholesterol 25-hydroxylase | -0.00541586 |
| SLC16A6 | solute carrier family 16, member 6 | -0.00538834 |
| RPS25 | ribosomal protein S25 | -0.0053823 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 | -0.00538065 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00535284 |
| IRS1 | insulin receptor substrate 1 | -0.00535061 |
| CCNB1 | cyclin B1 | -0.0053451 |
| HOXC10 | homeobox C10 | -0.00534445 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0053322 |
| SRGN | serglycin | -0.00533126 |
| GPX4 | glutathione peroxidase 4 | -0.00532683 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0053252 |
| SEPTIN8 | septin 8 | -0.00530259 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00530213 |
| FBN2 | fibrillin 2 | -0.00530064 |
| JADE3 | jade family PHD finger 3 | -0.00529957 |
| MXRA8 | matrix-remodelling associated 8 | -0.00528886 |
| FZD5 | frizzled class receptor 5 | -0.00528622 |
| BMP6 | bone morphogenetic protein 6 | -0.0052667 |
| SATB2 | SATB homeobox 2 | -0.00526202 |
| FCRL2 | Fc receptor-like 2 | -0.00525632 |
| SHTN1 | shootin 1 | -0.00525431 |
| UBB | ubiquitin B | -0.00525286 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00525231 |
| FA2H | fatty acid 2-hydroxylase | -0.00523923 |
| WDR48 | WD repeat domain 48 | -0.00523441 |
| HMP19 | HMP19 protein | -0.00523315 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00522749 |
| AREG | amphiregulin | -0.00522652 |
| CLDND1 | claudin domain containing 1 | -0.00522432 |
| ESD | esterase D | -0.00520904 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00519561 |
| NUTF2 | nuclear transport factor 2 | -0.00519267 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00518421 |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 | -0.00518092 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00517836 |
| CKAP2 | cytoskeleton associated protein 2 | -0.00517253 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00516557 |
| PENK | proenkephalin | -0.00516483 |
| CLCA4 | chloride channel accessory 4 | -0.00516362 |
| IL1R2 | interleukin 1 receptor, type II | -0.00515641 |
| OLA1 | Obg-like ATPase 1 | -0.00514569 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00513926 |
| ZNF536 | zinc finger protein 536 | -0.00513107 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00510576 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.0051008 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.00509635 |
| TSPAN6 | tetraspanin 6 | -0.00509319 |
| FKBP3 | FK506 binding protein 3, 25kDa | -0.00509301 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00509019 |
| ACTL6B | actin-like 6B | -0.00508017 |
| GLRX3 | glutaredoxin 3 | -0.00507946 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00507583 |
| TJP2 | tight junction protein 2 | -0.00507422 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00506832 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.00506542 |
| CALCRL | calcitonin receptor-like | -0.00505185 |
| A2M | alpha-2-macroglobulin | -0.00504433 |
| OLFM1 | olfactomedin 1 | -0.00504153 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.0050239 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0049953 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | -0.0049787 |
| LYZ | lysozyme | -0.00497601 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00494933 |
