| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | integrin, alpha V|This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. Note that the integrin alpha 5 and integrin alpha V chains are produced by distinct genes. [provided by RefSeq, Jan 2015] (NCBI Entrez Gene Database, 3685) |
| External Link | https://ncbi.nlm.nih.gov/gene/3685 |
| Similar Terms | |
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498 genes differentially expressed following the ITGAV gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0116345 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0108407 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.0108098 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.010309 |
| CA12 | carbonic anhydrase XII | 0.010244 |
| CFB | complement factor B | 0.0100144 |
| GPX2 | glutathione peroxidase 2 | 0.00935811 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00929147 |
| FGG | fibrinogen gamma chain | 0.00928659 |
| SPP1 | secreted phosphoprotein 1 | 0.00898883 |
| RAP1GAP | RAP1 GTPase activating protein | 0.00872046 |
| LXN | latexin | 0.0086559 |
| ADIRF | adipogenesis regulatory factor | 0.00853141 |
| KYNU | kynureninase | 0.00851237 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00844547 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00842653 |
| TMEM176B | transmembrane protein 176B | 0.00837166 |
| STC1 | stanniocalcin 1 | 0.00836384 |
| SELENBP1 | selenium binding protein 1 | 0.00820783 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00813144 |
| S100P | S100 calcium binding protein P | 0.00812047 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00789861 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00786247 |
| CFI | complement factor I | 0.00785312 |
| METTL7A | methyltransferase like 7A | 0.00785021 |
| ASS1 | argininosuccinate synthase 1 | 0.00774749 |
| FGB | fibrinogen beta chain | 0.00773478 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00772443 |
| CST1 | cystatin SN | 0.0077165 |
| CLU | clusterin | 0.00762932 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00761618 |
| TRIB2 | tribbles pseudokinase 2 | 0.0075705 |
| PLXNC1 | plexin C1 | 0.00752705 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00752269 |
| ALB | albumin | 0.00751886 |
| GPER1 | G protein-coupled estrogen receptor 1 | 0.00740946 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00731269 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00723241 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00720572 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00716252 |
| CTSK | cathepsin K | 0.00711749 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00703092 |
| TPBG | trophoblast glycoprotein | 0.00697922 |
| CFH | complement factor H | 0.00695533 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00692591 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.0069085 |
| HNMT | histamine N-methyltransferase | 0.00681406 |
| ATP9A | ATPase, class II, type 9A | 0.0067982 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00679646 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00679359 |
| MME | membrane metallo-endopeptidase | 0.00669724 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00669376 |
| S100A8 | S100 calcium binding protein A8 | 0.00666678 |
| PDGFD | platelet derived growth factor D | 0.00663718 |
| PLAT | plasminogen activator, tissue | 0.00663276 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.00661177 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00659697 |
| DUSP6 | dual specificity phosphatase 6 | 0.00659618 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00656611 |
| C3 | complement component 3 | 0.00655023 |
| TST | thiosulfate sulfurtransferase (rhodanese) | 0.00654433 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00652055 |
| CA2 | carbonic anhydrase II | 0.00646244 |
| SMAD7 | SMAD family member 7 | 0.00644847 |
| GDF15 | growth differentiation factor 15 | 0.00641967 |
| GPR137B | G protein-coupled receptor 137B | 0.0063975 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00639428 |
| LMBRD1 | LMBR1 domain containing 1 | 0.00636582 |
| FGA | fibrinogen alpha chain | 0.00636261 |
| PLD3 | phospholipase D family, member 3 | 0.00633931 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00632379 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00630909 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 0.00626109 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00625138 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00624409 |
| GPX3 | glutathione peroxidase 3 | 0.00618889 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00617686 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00614594 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00613711 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0060526 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00597612 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00591495 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00589287 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00586863 |
| NTS | neurotensin | 0.00586159 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00580581 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00579697 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00579664 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00577115 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00575961 |
| SDC1 | syndecan 1 | 0.00571508 |
| NDRG1 | N-myc downstream regulated 1 | 0.00571241 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00570719 |
| MLPH | melanophilin | 0.0056852 |
| MMP7 | matrix metallopeptidase 7 | 0.00566377 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 0.00560543 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00559619 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00557628 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00555123 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00553469 |
| FOXF1 | forkhead box F1 | 0.00551928 |
| GSTK1 | glutathione S-transferase kappa 1 | 0.00549437 |
| GUSB | glucuronidase, beta | 0.00548159 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00544927 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.0054433 |
| JUP | junction plakoglobin | 0.0054375 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 0.0054312 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00540841 |
| A2M | alpha-2-macroglobulin | 0.00540431 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00540115 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00538161 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00535331 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0053517 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00534512 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.00533572 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00532351 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00532345 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00532168 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00530151 |
| MMD | monocyte to macrophage differentiation-associated | 0.00529776 |
| ABHD6 | abhydrolase domain containing 6 | 0.00528193 |
| CPM | carboxypeptidase M | 0.00526143 |
| CTSH | cathepsin H | 0.00525146 |
| CES1 | carboxylesterase 1 | 0.00524869 |
| EGF | epidermal growth factor | 0.00523136 |
| OLFML2A | olfactomedin-like 2A | 0.00522716 |
| AGR2 | anterior gradient 2 | 0.00521213 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00520136 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00519417 |
| C5 | complement component 5 | 0.00517763 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.0051429 |
| PDZK1 | PDZ domain containing 1 | 0.00513018 |
| ACOT13 | acyl-CoA thioesterase 13 | 0.00511968 |
| NOTCH1 | notch 1 | 0.00510584 |
| STAP2 | signal transducing adaptor family member 2 | 0.00510562 |
| IL1R1 | interleukin 1 receptor, type I | 0.00509541 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00508089 |
| CP | ceruloplasmin (ferroxidase) | 0.00504718 |
| NCOA2 | nuclear receptor coactivator 2 | 0.00504336 |
| BTG2 | BTG family, member 2 | 0.00503843 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00503122 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.005024 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.0050231 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00501327 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00500694 |
| APOC1 | apolipoprotein C-I | 0.00500276 |
| ITGB4 | integrin, beta 4 | 0.0050019 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00496995 |
| CSTA | cystatin A (stefin A) | 0.00496985 |
| TOX3 | TOX high mobility group box family member 3 | 0.00496969 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00496153 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00495815 |
| SERINC5 | serine incorporator 5 | 0.00493791 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00493516 |
| TSKU | tsukushi, small leucine rich proteoglycan | 0.00492544 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 0.00491113 |
| DIO1 | deiodinase, iodothyronine, type I | 0.00491095 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00490313 |
| FGF13 | fibroblast growth factor 13 | 0.00490188 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00490044 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | 0.00490038 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00489875 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00488517 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00488409 |
| CFD | complement factor D (adipsin) | 0.00486875 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00485607 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00485405 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00484225 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00483525 |
| ADD3 | adducin 3 (gamma) | 0.00482906 |
| MXRA5 | matrix-remodelling associated 5 | 0.00481273 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00479803 |
| AREG | amphiregulin | 0.00479681 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00479485 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00479469 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00479297 |
| ASPA | aspartoacylase | 0.00477565 |
| MECOM | MDS1 and EVI1 complex locus | 0.00475825 |
| OLFML3 | olfactomedin-like 3 | 0.00475187 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.004747 |
| PLXNB2 | plexin B2 | 0.00474631 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00473074 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.00472447 |
| PENK | proenkephalin | 0.00472096 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C | 0.00471834 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | 0.00471613 |
| GPC3 | glypican 3 | 0.00471094 |
| PEPD | peptidase D | 0.00469647 |
| NID2 | nidogen 2 (osteonidogen) | 0.00468951 |
| KRT13 | keratin 13, type I | 0.00468797 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00467563 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0046742 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00467192 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00467021 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00466273 |
| TBX2 | T-box 2 | 0.00465569 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 | 0.0046534 |
| MMP12 | matrix metallopeptidase 12 | 0.00463233 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00463209 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.00462326 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00459533 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00458642 |
| VEGFA | vascular endothelial growth factor A | 0.00458309 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.00458074 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00457898 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00457299 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00457072 |
| THY1 | Thy-1 cell surface antigen | 0.00456508 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00456329 |
| TBX3 | T-box 3 | 0.00454735 |
| MPZL2 | myelin protein zero-like 2 | 0.00454622 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.00453857 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00453094 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00452942 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00452851 |
| GOLGA8A | golgin A8 family, member A | 0.00452604 |
| PLPP3 | phospholipid phosphatase 3 | 0.00452488 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00452478 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00451957 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.0045033 |
| CAPN3 | calpain 3, (p94) | 0.00450084 |
| DPEP1 | dipeptidase 1 (renal) | 0.00449543 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | 0.00448767 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00448309 |
| APOL1 | apolipoprotein L, 1 | 0.00447195 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.00445852 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00445472 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00444614 |
| COLEC12 | collectin sub-family member 12 | 0.00444454 |
| HGD | homogentisate 1,2-dioxygenase | 0.00443856 |
| C4BPA | complement component 4 binding protein, alpha | 0.00443621 |
| PDE8B | phosphodiesterase 8B | 0.00443482 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.00443289 |
| PON3 | paraoxonase 3 | 0.00443271 |
| KIAA0930 | KIAA0930 | 0.00443072 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00442243 |
| FGL1 | fibrinogen-like 1 | 0.0044091 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00439864 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00439724 |
| TMEM176A | transmembrane protein 176A | 0.00439606 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00439374 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.00437172 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00436257 |
| NRCAM | neuronal cell adhesion molecule | 0.00435886 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00435415 |
| REG1A | regenerating islet-derived 1 alpha | 0.00435206 |
| RBM47 | RNA binding motif protein 47 | 0.0043434 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00434019 |
| MMP1 | matrix metallopeptidase 1 | 0.00432958 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PITX3 | paired-like homeodomain 3 | -0.00975612 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00774746 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00771803 |
| TUBB6 | tubulin, beta 6 class V | -0.00751115 |
| GUCY2C | guanylate cyclase 2C | -0.0072644 |
| CCNA2 | cyclin A2 | -0.00724196 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00716448 |
| FOSL1 | FOS-like antigen 1 | -0.0070719 |
| MYBPC1 | myosin binding protein C, slow type | -0.00705054 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | -0.00673811 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00651108 |
| MPO | myeloperoxidase | -0.00647151 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00642274 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00629851 |
| SELL | selectin L | -0.00618139 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00604177 |
| PEG3 | paternally expressed 3 | -0.00596098 |
| ODC1 | ornithine decarboxylase 1 | -0.00595486 |
| MLF1 | myeloid leukemia factor 1 | -0.00589208 |
| NMT2 | N-myristoyltransferase 2 | -0.00583266 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00573744 |
| MCM6 | minichromosome maintenance complex component 6 | -0.00569261 |
| CCN2 | cellular communication network factor 2 | -0.00559437 |
| CHI3L2 | chitinase 3-like 2 | -0.00556378 |
| COL4A1 | collagen, type IV, alpha 1 | -0.00556026 |
| SACS | sacsin molecular chaperone | -0.00555851 |
| SOAT1 | sterol O-acyltransferase 1 | -0.00553455 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.00553276 |
| FSTL1 | follistatin-like 1 | -0.0055324 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00550598 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00548803 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.005483 |
| GOLM1 | golgi membrane protein 1 | -0.00547582 |
| SAC3D1 | SAC3 domain containing 1 | -0.00544268 |
| MEX3D | mex-3 RNA binding family member D | -0.00543856 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00543591 |
| ANXA6 | annexin A6 | -0.00540054 |
| CEP55 | centrosomal protein 55kDa | -0.00536372 |
| IFT57 | intraflagellar transport 57 | -0.00533719 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00530507 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00529031 |
| NEK7 | NIMA-related kinase 7 | -0.0052733 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00524391 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00519859 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00513235 |
| PCNA | proliferating cell nuclear antigen | -0.00513191 |
| FJX1 | four jointed box 1 (Drosophila) | -0.0050991 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00507738 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00505192 |
| CD1E | CD1e molecule | -0.00504337 |
| CCNB2 | cyclin B2 | -0.00503414 |
| FERMT2 | fermitin family member 2 | -0.00503335 |
| CAV2 | caveolin 2 | -0.00500841 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0050074 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 | -0.00500392 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | -0.00497418 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00496529 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00496425 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00495777 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00495747 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00494315 |
| CST6 | cystatin E/M | -0.0049277 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.00492578 |
| CD1B | CD1b molecule | -0.00491156 |
| CYBRD1 | cytochrome b reductase 1 | -0.00488111 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00486541 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | -0.00485652 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.00485194 |
| ACTL6A | actin-like 6A | -0.00484906 |
| RAD51 | RAD51 recombinase | -0.00484196 |
| SPAG1 | sperm associated antigen 1 | -0.00484167 |
| UNG | uracil-DNA glycosylase | -0.00483428 |
| WT1 | Wilms tumor 1 | -0.00481613 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00481422 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00480823 |
| TGFB2 | transforming growth factor, beta 2 | -0.00477217 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00477139 |
| C5ORF28 | chromosome 5 open reading frame 28 | -0.00476769 |
| IL32 | interleukin 32 | -0.00475101 |
| METTL8 | methyltransferase like 8 | -0.00470228 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.00468306 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.00466859 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00466472 |
| CNN3 | calponin 3, acidic | -0.0046503 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00464594 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.00463582 |
| CCNB1 | cyclin B1 | -0.0046347 |
| RANBP1 | RAN binding protein 1 | -0.00463441 |
| PRPF19 | pre-mRNA processing factor 19 | -0.00462786 |
| LDLR | low density lipoprotein receptor | -0.00460499 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00459449 |
| CHPT1 | choline phosphotransferase 1 | -0.004591 |
| COL2A1 | collagen, type II, alpha 1 | -0.00458466 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.00455729 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -0.00453555 |
| GLS | glutaminase | -0.00453241 |
| MAGEA4 | melanoma antigen family A4 | -0.0044996 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -0.00447112 |
| NTAQ1 | N-terminal glutamine amidase 1 | -0.00446413 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00441735 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00440876 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00439751 |
| AXL | AXL receptor tyrosine kinase | -0.00438642 |
| SEPTIN6 | septin 6 | -0.00438071 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -0.00438038 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00436807 |
| TUBB4B | tubulin, beta 4B class IVb | -0.00436093 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00435781 |
| RAB3B | RAB3B, member RAS oncogene family | -0.00435205 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.0043495 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00434098 |
| KAZN | kazrin, periplakin interacting protein | -0.00433658 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00433348 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00432238 |
| TYMS | thymidylate synthetase | -0.00432179 |
| ZNF468 | zinc finger protein 468 | -0.00430709 |
| AMOTL2 | angiomotin like 2 | -0.00429841 |
| CRY1 | cryptochrome circadian clock 1 | -0.0042937 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | -0.00427588 |
| TEAD4 | TEA domain family member 4 | -0.00427258 |
| SMC2 | structural maintenance of chromosomes 2 | -0.00426264 |
| IL1A | interleukin 1, alpha | -0.00426192 |
| MRPL42 | mitochondrial ribosomal protein L42 | -0.00425659 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -0.004255 |
| KLHL7 | kelch-like family member 7 | -0.0042522 |
| KLF6 | Kruppel-like factor 6 | -0.0042406 |
| CDCA3 | cell division cycle associated 3 | -0.00423116 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00422355 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00420415 |
| EREG | epiregulin | -0.00418573 |
| PIP | prolactin-induced protein | -0.00416688 |
| TPX2 | TPX2, microtubule-associated | -0.00415191 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | -0.00414889 |
| FNBP1 | formin binding protein 1 | -0.00413936 |
| CHEK1 | checkpoint kinase 1 | -0.0041304 |
| ELANE | elastase, neutrophil expressed | -0.00412109 |
| RPIA | ribose 5-phosphate isomerase A | -0.00410573 |
| NUP155 | nucleoporin 155kDa | -0.00410387 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00410382 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 | -0.00409741 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00409573 |
| EGFR | epidermal growth factor receptor | -0.00409052 |
| LMNB1 | lamin B1 | -0.0040905 |
| ADA | adenosine deaminase | -0.00408806 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0040789 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | -0.00407715 |
| STMN1 | stathmin 1 | -0.00407411 |
| CDC42 | cell division cycle 42 | -0.00407106 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00406939 |
| MSH2 | mutS homolog 2 | -0.00406518 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00406061 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00405224 |
| TLCD3A | TLC domain containing 3A | -0.00404564 |
| BAG2 | BCL2-associated athanogene 2 | -0.00404529 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00404183 |
| CDC45 | cell division cycle 45 | -0.0040294 |
| DSE | dermatan sulfate epimerase | -0.00402665 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00402304 |
| AQP4 | aquaporin 4 | -0.0040209 |
| NAV3 | neuron navigator 3 | -0.00401866 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00401838 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00399972 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00399946 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00398514 |
| THBS1 | thrombospondin 1 | -0.00397847 |
| MCM10 | minichromosome maintenance complex component 10 | -0.00396148 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.00395232 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.0039448 |
| HAT1 | histone acetyltransferase 1 | -0.00394356 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00394073 |
| CENPN | centromere protein N | -0.00392707 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00392478 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00391966 |
| FABP7 | fatty acid binding protein 7, brain | -0.00390619 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00390199 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.0038866 |
| RAB23 | RAB23, member RAS oncogene family | -0.00388554 |
| KIF15 | kinesin family member 15 | -0.00388231 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00388218 |
| PLIN3 | perilipin 3 | -0.00386914 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | -0.003859 |
| CPOX | coproporphyrinogen oxidase | -0.00385861 |
| CANT1 | calcium activated nucleotidase 1 | -0.00384597 |
| NCBP2 | nuclear cap binding protein subunit 2, 20kDa | -0.00384398 |
| ELOVL4 | ELOVL fatty acid elongase 4 | -0.00383597 |
| DLX2 | distal-less homeobox 2 | -0.00383495 |
| COG5 | component of oligomeric golgi complex 5 | -0.00382866 |
| DONSON | downstream neighbor of SON | -0.00382147 |
| MXRA7 | matrix-remodelling associated 7 | -0.00382099 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.00381548 |
| NKX3-1 | NK3 homeobox 1 | -0.00381349 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -0.00381259 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00380096 |
| NUP160 | nucleoporin 160kDa | -0.00379688 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00379332 |
| PRPF4 | pre-mRNA processing factor 4 | -0.00379264 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00379137 |
| PKP2 | plakophilin 2 | -0.00378651 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0037843 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00378249 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.0037803 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.00377922 |
| TICAM1 | toll-like receptor adaptor molecule 1 | -0.00377069 |
| LGALSL | lectin, galactoside-binding-like | -0.00375994 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00375969 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00375747 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00375411 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0037446 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) | -0.00374397 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | -0.00374123 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0037408 |
| WDR12 | WD repeat domain 12 | -0.00373334 |
| INHBA | inhibin, beta A | -0.00371176 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00370157 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.00370023 |
| ADRB2 | adrenoceptor beta 2, surface | -0.00368855 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0036874 |
| MAGEA3 | melanoma antigen family A3 | -0.0036775 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.00367729 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00367299 |
| WDR47 | WD repeat domain 47 | -0.00366061 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.00366024 |
| SEH1L | SEH1-like (S. cerevisiae) | -0.00365647 |
| GLTP | glycolipid transfer protein | -0.00365463 |
| LHFP | lipoma HMGIC fusion partner | -0.00365458 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00365364 |
| RND3 | Rho family GTPase 3 | -0.00365277 |
| KIF20A | kinesin family member 20A | -0.00365014 |
| DCLRE1C | DNA cross-link repair 1C | -0.00364875 |
| DESI1 | desumoylating isopeptidase 1 | -0.00364623 |
| AMPH | amphiphysin | -0.00363077 |
| RRM2 | ribonucleotide reductase M2 | -0.00362707 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.003627 |
| TAGLN | transgelin | -0.00362403 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0036235 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -0.00362332 |
| SYNC | syncoilin, intermediate filament protein | -0.00362158 |
| IPO5 | importin 5 | -0.00361548 |
| HOPX | HOP homeobox | -0.00361456 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.00360556 |
| RRM1 | ribonucleotide reductase M1 | -0.00360396 |
| TSPAN5 | tetraspanin 5 | -0.00359987 |
| XIC | X chromosome inactivation center | -0.00359476 |
| DDI2 | DNA-damage inducible 1 homolog 2 (S. cerevisiae) | -0.00358962 |
| AK4 | adenylate kinase 4 | -0.00358756 |
| SRP9 | signal recognition particle 9kDa | -0.00358726 |
| KLHDC8A | kelch domain containing 8A | -0.00358112 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.00357864 |
| NPR3 | natriuretic peptide receptor 3 | -0.00356624 |
