ITGB1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)|Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3688)
External Link https://ncbi.nlm.nih.gov/gene/3688
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Genes

499 genes differentially expressed following the ITGB1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0181549
CSTA cystatin A (stefin A) 0.0178155
STK10 serine/threonine kinase 10 0.016653
FABP7 fatty acid binding protein 7, brain 0.0160583
CA12 carbonic anhydrase XII 0.0157275
NUSAP1 nucleolar and spindle associated protein 1 0.0138874
KRT5 keratin 5, type II 0.0138727
CEMIP cell migration inducing protein, hyaluronan binding 0.0132173
GPM6B glycoprotein M6B 0.0125771
CHI3L2 chitinase 3-like 2 0.0124877
TMEM45A transmembrane protein 45A 0.0122008
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0121807
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0117442
PRR7 proline rich 7 (synaptic) 0.0116536
KRT6A keratin 6A, type II 0.0115861
FCGBP Fc fragment of IgG binding protein 0.0115253
S100A7 S100 calcium binding protein A7 0.0112943
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0112589
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0110975
MAP2K6 mitogen-activated protein kinase kinase 6 0.0110587
PI3 peptidase inhibitor 3, skin-derived 0.0110019
OCRL oculocerebrorenal syndrome of Lowe 0.0108002
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.0107957
POSTN periostin, osteoblast specific factor 0.0106793
LY6D lymphocyte antigen 6 complex, locus D 0.0106025
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.0103793
SPINK5 serine peptidase inhibitor, Kazal type 5 0.0102506
KIAA0226L KIAA0226-like 0.0101898
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0101063
TUBB2A tubulin, beta 2A class IIa 0.0100976
CXCL5 chemokine (C-X-C motif) ligand 5 0.00956417
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00946395
FAR2 fatty acyl CoA reductase 2 0.00934304
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00928743
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00918149
KRT14 keratin 14, type I 0.00911256
TXNDC9 thioredoxin domain containing 9 0.00903911
NRN1 neuritin 1 0.00894249
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0089201
TUBB2B tubulin, beta 2B class IIb 0.00888747
KDM5D lysine (K)-specific demethylase 5D 0.00886822
RPA3 replication protein A3, 14kDa 0.00883747
ZIC1 Zic family member 1 0.00883331
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00882886
CXCL14 chemokine (C-X-C motif) ligand 14 0.00873887
S100A2 S100 calcium binding protein A2 0.00872041
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.00866369
LOR loricrin 0.00864946
COL3A1 collagen, type III, alpha 1 0.00856803
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00852285
COL1A2 collagen, type I, alpha 2 0.00851593
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00849724
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00841239
SPRR1B small proline-rich protein 1B 0.00836797
AQP3 aquaporin 3 (Gill blood group) 0.00826488
LXN latexin 0.00826456
TMEM14A transmembrane protein 14A 0.00824452
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00817875
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00817742
CALML5 calmodulin-like 5 0.00817523
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00810128
COCH cochlin 0.00809294
LTF lactotransferrin 0.00800536
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00800229
CXCL8 chemokine (C-X-C motif) ligand 8 0.00796609
ZNF589 zinc finger protein 589 0.00794466
NTS neurotensin 0.00793621
THY1 Thy-1 cell surface antigen 0.00792148
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00791926
KRT1 keratin 1, type II 0.00784502
SRGN serglycin 0.00784455
MEN1 multiple endocrine neoplasia I 0.00778823
PDE4B phosphodiesterase 4B, cAMP-specific 0.00777463
CLCA1 chloride channel accessory 1 0.0077679
IL1R2 interleukin 1 receptor, type II 0.00775745
MOXD1 monooxygenase, DBH-like 1 0.00771714
PKP1 plakophilin 1 0.00769855
TRIM29 tripartite motif containing 29 0.00762228
ADORA2B adenosine A2b receptor 0.00761353
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00758475
CLEC2B C-type lectin domain family 2, member B 0.00757911
PADI2 peptidyl arginine deiminase, type II 0.00754319
CD59 CD59 molecule, complement regulatory protein 0.00747108
KRT2 keratin 2, type II 0.00745152
LYZ lysozyme 0.00744863
FRZB frizzled-related protein 0.00744794
S100B S100 calcium binding protein B 0.00743498
KRT15 keratin 15, type I 0.00736714
UBE2N ubiquitin-conjugating enzyme E2N 0.00735003
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.0073375
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0072728
F12 coagulation factor XII (Hageman factor) 0.00721384
NELL2 NEL-like 2 (chicken) 0.00720429
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00713725
CRYBG1 crystallin beta-gamma domain containing 1 0.00712455
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00709734
MAOB monoamine oxidase B 0.00708782
CLDN10 claudin 10 0.00708508
CALML3 calmodulin-like 3 0.0070642
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00699567
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.0069871
DOK5 docking protein 5 0.00696601
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00694081
GJA1 gap junction protein, alpha 1, 43kDa 0.00686774
ADM adrenomedullin 0.00685822
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00684527
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.00684493
SKP1 S-phase kinase-associated protein 1 0.00684353
CETN2 centrin, EF-hand protein, 2 0.00675147
ANGEL2 angel homolog 2 (Drosophila) 0.00672002
KRT13 keratin 13, type I 0.00670478
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00669819
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.00667123
GSTA4 glutathione S-transferase alpha 4 0.00665476
FOXC1 forkhead box C1 0.00665098
IFT52 intraflagellar transport 52 0.00665049
SUB1 SUB1 homolog (S. cerevisiae) 0.00664744
GPATCH8 G patch domain containing 8 0.0066375
COG2 component of oligomeric golgi complex 2 0.00663705
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00661495
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00660679
ASB13 ankyrin repeat and SOCS box containing 13 0.00657331
TMEM168 transmembrane protein 168 0.00655374
KRT23 keratin 23, type I 0.00651981
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.00650666
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00649278
FGFR1 fibroblast growth factor receptor 1 0.00649139
CD83 CD83 molecule 0.00648705
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00648068
MSMO1 methylsterol monooxygenase 1 0.00647303
SIRT3 sirtuin 3 0.00643897
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00641482
LYPD3 LY6/PLAUR domain containing 3 0.00637762
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.00636831
EAPP E2F-associated phosphoprotein 0.00635295
HMGN4 high mobility group nucleosomal binding domain 4 0.00632328
PEX2 peroxisomal biogenesis factor 2 0.00630198
CNN3 calponin 3, acidic 0.0062882
LMNB1 lamin B1 0.00628738
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00624343
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00621843
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00621802
LTBP1 latent transforming growth factor beta binding protein 1 0.00620946
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.006198
FERMT1 fermitin family member 1 0.00619764
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00619681
FAM234B family with sequence similarity 234 member B 0.00618472
IQCG IQ motif containing G 0.00618237
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 0.0061819
ACAT2 acetyl-CoA acetyltransferase 2 0.00617018
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00616178
KRT16 keratin 16, type I 0.00614741
SPRR2B small proline-rich protein 2B 0.00613386
DCK deoxycytidine kinase 0.00612845
ACP6 acid phosphatase 6, lysophosphatidic 0.00612725
ANXA2P2 annexin A2 pseudogene 2 0.00612456
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.00610645
GFAP glial fibrillary acidic protein 0.00610255
JAG1 jagged 1 0.00609985
CCL20 chemokine (C-C motif) ligand 20 0.00609839
CD248 CD248 molecule, endosialin 0.00608135
COL2A1 collagen, type II, alpha 1 0.0060779
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.00605292
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00604206
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00603046
CHP2 calcineurin-like EF-hand protein 2 0.00602513
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.00596915
RGCC regulator of cell cycle 0.00593028
MAGEH1 melanoma antigen family H1 0.00590614
AHCYL2 adenosylhomocysteinase-like 2 0.00590483
GYPC glycophorin C (Gerbich blood group) 0.00590115
IL1RAP interleukin 1 receptor accessory protein 0.00589769
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00586719
HAL histidine ammonia-lyase 0.0058545
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 0.00585129
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase 0.005851
ENOPH1 enolase-phosphatase 1 0.00584688
RPP40 ribonuclease P/MRP 40kDa subunit 0.00584493
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 0.00584324
DSG3 desmoglein 3 0.00583864
KRT6B keratin 6B, type II 0.00583705
SRI sorcin 0.00582588
SEPP1 selenoprotein P, plasma, 1 0.00581921
TSPAN7 tetraspanin 7 0.00580929
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00578851
SPRR3 small proline-rich protein 3 0.00577699
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00577499
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.00577037
ENO2 enolase 2 (gamma, neuronal) 0.00576671
APOC1 apolipoprotein C-I 0.00576176
ZFAND1 zinc finger, AN1-type domain 1 0.0057456
DLD dihydrolipoamide dehydrogenase 0.00572587
APOC2 apolipoprotein C-II 0.00570213
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 0.00567781
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00566884
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.00566605
SPRR1A small proline-rich protein 1A 0.00566317
SUSD4 sushi domain containing 4 0.00565833
NCK1 NCK adaptor protein 1 0.00564349
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00564271
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.00564125
PHACTR1 phosphatase and actin regulator 1 0.00564121
CRIPT cysteine-rich PDZ-binding protein 0.00562438
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.00562218
METTL21B methyltransferase like 21B 0.00560669
PIP prolactin-induced protein 0.00560508
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.00559449
SPTSSA serine palmitoyltransferase, small subunit A 0.0055885
EIF4E eukaryotic translation initiation factor 4E 0.00557352
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0055566
BPIFA1 BPI fold containing family A, member 1 0.00554906
TDP2 tyrosyl-DNA phosphodiesterase 2 0.00554295
AQP9 aquaporin 9 0.00553935
CLCA4 chloride channel accessory 4 0.00553933
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00552567
RPS5 ribosomal protein S5 0.00551835
PLPBP pyridoxal phosphate binding protein 0.00550687
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00550502
CYTL1 cytokine-like 1 0.00548839
AKAP12 A kinase (PRKA) anchor protein 12 0.00547865
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.0054782
CD200 CD200 molecule 0.00547076
RAPSN receptor-associated protein of the synapse 0.00546644
LARS1 leucyl-tRNA synthetase 1 0.00545954
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) 0.00545758
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00545737
POPDC3 popeye domain containing 3 0.00545373
THAP12 THAP domain containing 12 0.00544133
HOXB7 homeobox B7 0.00542991
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.00542143
TAGLN transgelin 0.00539943
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00539431
SRSF6 serine/arginine-rich splicing factor 6 0.00539327
HSPA2 heat shock 70kDa protein 2 0.00539124
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.00538896
NMU neuromedin U 0.00537264
ACOT7 acyl-CoA thioesterase 7 0.00536594
COMMD8 COMM domain containing 8 0.00536475
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00533922
C21ORF62 chromosome 21 open reading frame 62 0.00533502
CENPE centromere protein E, 312kDa 0.00533256
NDN necdin, melanoma antigen (MAGE) family member 0.00532524
RCAN1 regulator of calcineurin 1 0.00531862
MREG melanoregulin 0.00531372
MMP12 matrix metallopeptidase 12 0.00530421
RAD23B RAD23 homolog B (S. cerevisiae) 0.00529886
COPS4 COP9 signalosome subunit 4 0.00529325
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00529225
CXCL12 chemokine (C-X-C motif) ligand 12 0.00528714
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00528026

decreased expression

Symbol Name Standardized Value
AREG amphiregulin -0.0147146
KRT7 keratin 7, type II -0.0143544
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0132989
GNAS GNAS complex locus -0.0123081
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0120469
LY6E lymphocyte antigen 6 complex, locus E -0.0118692
PLAAT3 phospholipase A and acyltransferase 3 -0.0117584
KRT18 keratin 18, type I -0.0117403
EPCAM epithelial cell adhesion molecule -0.0111983
GPX3 glutathione peroxidase 3 -0.011167
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0110436
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0103959
XIC X chromosome inactivation center -0.0100636
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0100027
SLIT2 slit homolog 2 (Drosophila) -0.00997373
CDR2L cerebellar degeneration-related protein 2-like -0.00975302
IRS1 insulin receptor substrate 1 -0.00941311
CDCA4 cell division cycle associated 4 -0.00932582
IFI44L interferon-induced protein 44-like -0.00930814
PHACTR2 phosphatase and actin regulator 2 -0.00926984
NXN nucleoredoxin -0.00919771
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00918251
RHOD ras homolog family member D -0.00914755
PLXNB2 plexin B2 -0.00913563
BMP2 bone morphogenetic protein 2 -0.00907946
TFPI2 tissue factor pathway inhibitor 2 -0.00906346
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00904719
MN1 meningioma (disrupted in balanced translocation) 1 -0.0090268
AMOTL2 angiomotin like 2 -0.00899852
SMAD7 SMAD family member 7 -0.00897145
IL7R interleukin 7 receptor -0.00886194
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00882937
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00880933
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00876521
KRT8 keratin 8, type II -0.00874007
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.0086489
TNS3 tensin 3 -0.00863418
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00855472
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00854795
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00849064
ATF3 activating transcription factor 3 -0.0084787
BRD4 bromodomain containing 4 -0.00847404
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00842994
LIMCH1 LIM and calponin homology domains 1 -0.00841637
VEGFC vascular endothelial growth factor C -0.00841419
BST2 bone marrow stromal cell antigen 2 -0.00840677
ZBTB16 zinc finger and BTB domain containing 16 -0.00836462
MAP7 microtubule-associated protein 7 -0.008287
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00826323
AMDHD2 amidohydrolase domain containing 2 -0.00825403
FOLR1 folate receptor 1 (adult) -0.00822537
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00819812
ST18 suppression of tumorigenicity 18, zinc finger -0.0081156
UBA1 ubiquitin-like modifier activating enzyme 1 -0.00810095
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00808292
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00798305
TUBA4A tubulin, alpha 4a -0.00791748
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00783255
TSC22D2 TSC22 domain family, member 2 -0.00779759
GSN gelsolin -0.00777241
NT5E 5'-nucleotidase, ecto (CD73) -0.00768356
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00766369
STIP1 stress-induced phosphoprotein 1 -0.0076322
TGM2 transglutaminase 2 -0.00763146
JUP junction plakoglobin -0.00761985
CLDN4 claudin 4 -0.00757446
DUSP5 dual specificity phosphatase 5 -0.00755333
SMAD3 SMAD family member 3 -0.00751763
COL10A1 collagen, type X, alpha 1 -0.00743265
COQ8A coenzyme Q8A -0.00742147
TOX3 TOX high mobility group box family member 3 -0.00740017
CCL8 chemokine (C-C motif) ligand 8 -0.00737132
PRSS8 protease, serine, 8 -0.00734335
AGR2 anterior gradient 2 -0.0073403
CDA cytidine deaminase -0.00733589
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00732877
DCN decorin -0.00727475
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -0.0072412
TNNT1 troponin T type 1 (skeletal, slow) -0.0072197
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00721086
DYNLL1 dynein, light chain, LC8-type 1 -0.00720741
ANXA3 annexin A3 -0.00712844
NKX2-1 NK2 homeobox 1 -0.00712754
SIL1 SIL1 nucleotide exchange factor -0.00709915
PLAU plasminogen activator, urokinase -0.00709382
ZBED2 zinc finger, BED-type containing 2 -0.00706379
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.0070355
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00701063
MX1 MX dynamin-like GTPase 1 -0.00697832
CLGN calmegin -0.00695731
ABHD4 abhydrolase domain containing 4 -0.00694694
EGR1 early growth response 1 -0.00692495
DPT dermatopontin -0.0068687
MFAP5 microfibrillar associated protein 5 -0.00682915
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00680399
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00680129
IDO1 indoleamine 2,3-dioxygenase 1 -0.00679756
ELF4 E74-like factor 4 (ets domain transcription factor) -0.00678532
PNMA8A PNMA family member 8A -0.00678281
LMNA lamin A/C -0.00678189
RBPMS RNA binding protein with multiple splicing -0.0067705
FNDC3B fibronectin type III domain containing 3B -0.00676446
ZBTB38 zinc finger and BTB domain containing 38 -0.00675709
LAPTM4B lysosomal protein transmembrane 4 beta -0.00675329
CDC34 cell division cycle 34 -0.00674721
APOA1 apolipoprotein A-I -0.00674476
COL14A1 collagen, type XIV, alpha 1 -0.00672224
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00670457
SLC38A1 solute carrier family 38, member 1 -0.00667321
PPL periplakin -0.00666954
ACTN4 actinin, alpha 4 -0.00666586
DEPTOR DEP domain containing MTOR-interacting protein -0.00666171
CAVIN1 caveolae associated protein 1 -0.0066554
KIF5B kinesin family member 5B -0.00661325
TICAM1 toll-like receptor adaptor molecule 1 -0.00659984
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.006597
FSTL3 follistatin-like 3 (secreted glycoprotein) -0.00659164
XAF1 XIAP associated factor 1 -0.00657136
CCNA2 cyclin A2 -0.00655147
GMPR guanosine monophosphate reductase -0.00653349
CCR2 chemokine (C-C motif) receptor 2 -0.00653026
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -0.00651561
QPRT quinolinate phosphoribosyltransferase -0.00651399
WASHC4 WASH complex subunit 4 -0.00648977
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00647855
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00646188
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00646066
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00645293
SFRP1 secreted frizzled-related protein 1 -0.00644474
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00643654
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.0064086
KANK2 KN motif and ankyrin repeat domains 2 -0.00639541
ADGRF5 adhesion G protein-coupled receptor F5 -0.00636339
LRP5 low density lipoprotein receptor-related protein 5 -0.0063203
L1CAM L1 cell adhesion molecule -0.00630973
IL6 interleukin 6 -0.00627319
ALDOB aldolase B, fructose-bisphosphate -0.0062602
LEPROT leptin receptor overlapping transcript -0.00622725
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00622309
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00620715
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00620417
S100A12 S100 calcium binding protein A12 -0.00618944
PDGFRL platelet-derived growth factor receptor-like -0.00617641
ADCY9 adenylate cyclase 9 -0.00616329
TPSAB1 tryptase alpha/beta 1 -0.00615565
CTSD cathepsin D -0.00615134
C2CD2 C2 calcium-dependent domain containing 2 -0.00613359
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00612464
CLDN3 claudin 3 -0.00611502
CNOT7 CCR4-NOT transcription complex, subunit 7 -0.00610194
MT2A metallothionein 2A -0.00610153
CRISP3 cysteine-rich secretory protein 3 -0.0060885
ACADVL acyl-CoA dehydrogenase, very long chain -0.00608453
MGLL monoglyceride lipase -0.00607624
BBX bobby sox homolog (Drosophila) -0.00606429
MPRIP myosin phosphatase Rho interacting protein -0.00606188
AFF1 AF4/FMR2 family, member 1 -0.00605648
E2F2 E2F transcription factor 2 -0.00601542
CLDN1 claudin 1 -0.00598368
F13A1 coagulation factor XIII, A1 polypeptide -0.00597942
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -0.00596621
CFH complement factor H -0.00596478
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.00595027
MITF microphthalmia-associated transcription factor -0.0059448
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00594019
MLXIP MLX interacting protein -0.00593473
STK25 serine/threonine kinase 25 -0.00592798
LONP1 lon peptidase 1, mitochondrial -0.0059221
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00591096
EDNRA endothelin receptor type A -0.00590399
BASP1 brain abundant, membrane attached signal protein 1 -0.00590332
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00588972
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00587506
GTPBP2 GTP binding protein 2 -0.00586925
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00584897
STX4 syntaxin 4 -0.0058236
RAD23A RAD23 homolog A (S. cerevisiae) -0.00582335
MECOM MDS1 and EVI1 complex locus -0.00581606
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00580982
TGFB1 transforming growth factor, beta 1 -0.00580291
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00579546
GOLGA2 golgin A2 -0.0057831
AP1M2 adaptor-related protein complex 1, mu 2 subunit -0.00577623
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -0.00577004
CRIP2 cysteine-rich protein 2 -0.00576868
TNIP1 TNFAIP3 interacting protein 1 -0.00576755
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00576693
GAS6 growth arrest-specific 6 -0.00576609
AOX1 aldehyde oxidase 1 -0.00576394
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00575212
TM4SF4 transmembrane 4 L six family member 4 -0.00574408
FAM50A family with sequence similarity 50, member A -0.00572995
ANKRD11 ankyrin repeat domain 11 -0.00572445
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00572429
MX2 MX dynamin-like GTPase 2 -0.00572143
NUMA1 nuclear mitotic apparatus protein 1 -0.00572132
SETD5 SET domain containing 5 -0.00571879
SCPEP1 serine carboxypeptidase 1 -0.00571473
NELL1 NEL-like 1 (chicken) -0.0057122
RIN2 Ras and Rab interactor 2 -0.00569668
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00569328
MPST mercaptopyruvate sulfurtransferase -0.00569288
TMEM248 transmembrane protein 248 -0.00568885
SFRP4 secreted frizzled-related protein 4 -0.00568488
PUM1 pumilio RNA-binding family member 1 -0.00568177
COMP cartilage oligomeric matrix protein -0.00566401
AKR1C3 aldo-keto reductase family 1, member C3 -0.00562547
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00562437
ISG15 ISG15 ubiquitin-like modifier -0.00562386
TSPAN4 tetraspanin 4 -0.00561753
TMPRSS4 transmembrane protease, serine 4 -0.00561352
KEAP1 kelch-like ECH-associated protein 1 -0.0056058
MVP major vault protein -0.00560496
CAPN1 calpain 1, (mu/I) large subunit -0.00559385
PROCR protein C receptor, endothelial -0.0055922
CLIC5 chloride intracellular channel 5 -0.00558017
BRD2 bromodomain containing 2 -0.00557506
CTSZ cathepsin Z -0.00556914
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00556069
MYRF myelin regulatory factor -0.00555521
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00555286
LAMB1 laminin, beta 1 -0.0055459
FKBP2 FK506 binding protein 2, 13kDa -0.0055447
TUFM Tu translation elongation factor, mitochondrial -0.00554396
CD163 CD163 molecule -0.00553791
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00553463
CHD4 chromodomain helicase DNA binding protein 4 -0.00552742
AHCYL1 adenosylhomocysteinase-like 1 -0.00552408
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00552052
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00551848
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.00551052
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.00550322
GUSB glucuronidase, beta -0.00550046
ABAT 4-aminobutyrate aminotransferase -0.0054991
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00549173
FOSL1 FOS-like antigen 1 -0.00548727
DUSP7 dual specificity phosphatase 7 -0.00547084
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00544039
GGT1 gamma-glutamyltransferase 1 -0.00543769
ZNF91 zinc finger protein 91 -0.00543234
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00542523
IGHMBP2 immunoglobulin mu binding protein 2 -0.00542475
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00541879
GRN granulin -0.00540617
CFB complement factor B -0.00540133
KCTD5 potassium channel tetramerization domain containing 5 -0.00539697
MT1G metallothionein 1G -0.00538253
PRKCSH protein kinase C substrate 80K-H -0.00537825
MT1H metallothionein 1H -0.00537193