ITGB3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)|The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3690)
External Link https://ncbi.nlm.nih.gov/gene/3690
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Genes

499 genes differentially expressed following the ITGB3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
S100A7 S100 calcium binding protein A7 0.0217829
GRB7 growth factor receptor-bound protein 7 0.0147687
S100A9 S100 calcium binding protein A9 0.0145822
ADM adrenomedullin 0.0144725
S100A8 S100 calcium binding protein A8 0.0142841
DAXX death-domain associated protein 0.0138095
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.0135951
CLEC2B C-type lectin domain family 2, member B 0.0131891
HSPB1 heat shock 27kDa protein 1 0.0125307
TMEM45A transmembrane protein 45A 0.0124991
EIF5A eukaryotic translation initiation factor 5A 0.0123231
PI3 peptidase inhibitor 3, skin-derived 0.0121961
RGCC regulator of cell cycle 0.0119363
FCGBP Fc fragment of IgG binding protein 0.011475
PLK1 polo-like kinase 1 0.0112333
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0110124
EDN3 endothelin 3 0.0103103
LOXL2 lysyl oxidase-like 2 0.0102699
ANXA1 annexin A1 0.0101971
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00994645
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00992424
KRT14 keratin 14, type I 0.00991657
CXCL14 chemokine (C-X-C motif) ligand 14 0.00956907
ZNF395 zinc finger protein 395 0.00956686
CD93 CD93 molecule 0.00956369
CLTB clathrin, light chain B 0.00955087
KRT17 keratin 17, type I 0.00951251
VSNL1 visinin-like 1 0.00945662
PDE4B phosphodiesterase 4B, cAMP-specific 0.00943527
MT1X metallothionein 1X 0.00930175
CA2 carbonic anhydrase II 0.00899817
GBP2 guanylate binding protein 2, interferon-inducible 0.00895149
AK4 adenylate kinase 4 0.00876149
INA internexin neuronal intermediate filament protein, alpha 0.00864862
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00863458
MMD monocyte to macrophage differentiation-associated 0.00863154
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00859936
MTUS1 microtubule associated tumor suppressor 1 0.00858718
OPHN1 oligophrenin 1 0.00852388
FSCN1 fascin actin-bundling protein 1 0.0085137
CXADR coxsackie virus and adenovirus receptor 0.00838096
LINC00623 long intergenic non-protein coding RNA 623 0.00836422
CD36 CD36 molecule (thrombospondin receptor) 0.00832412
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00829758
CLDN8 claudin 8 0.00824601
COL3A1 collagen, type III, alpha 1 0.00819632
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00818109
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00817977
IL32 interleukin 32 0.00816253
ACKR3 atypical chemokine receptor 3 0.00815622
MX2 MX dynamin-like GTPase 2 0.00814843
MT1F metallothionein 1F 0.00812814
HOXB7 homeobox B7 0.00811757
RNASET2 ribonuclease T2 0.00806317
PRAME preferentially expressed antigen in melanoma 0.00806304
PEG3 paternally expressed 3 0.00803771
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.00802337
C3 complement component 3 0.00798617
SRGN serglycin 0.00795873
CHP1 calcineurin-like EF-hand protein 1 0.00794642
GJA1 gap junction protein, alpha 1, 43kDa 0.007936
SCD5 stearoyl-CoA desaturase 5 0.00792281
STOM stomatin 0.0078536
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00779399
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00778501
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00778389
MME membrane metallo-endopeptidase 0.00776689
EVI2A ecotropic viral integration site 2A 0.00771861
SPRR3 small proline-rich protein 3 0.00771795
KYNU kynureninase 0.0075989
SPRR1B small proline-rich protein 1B 0.00755817
SLC35G2 solute carrier family 35, member G2 0.00755303
CRABP1 cellular retinoic acid binding protein 1 0.00752961
AQP3 aquaporin 3 (Gill blood group) 0.00752905
IL1RN interleukin 1 receptor antagonist 0.00750712
WDR7 WD repeat domain 7 0.00750274
METRN meteorin, glial cell differentiation regulator 0.00748878
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00739405
FGB fibrinogen beta chain 0.00738869
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00736875
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00732197
MT1G metallothionein 1G 0.00731522
MMP11 matrix metallopeptidase 11 0.00730975
ISG15 ISG15 ubiquitin-like modifier 0.007233
CSTA cystatin A (stefin A) 0.00723264
MAL mal, T-cell differentiation protein 0.00719122
SCGB2A2 secretoglobin, family 2A, member 2 0.0071862
CA4 carbonic anhydrase IV 0.0071659
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00714267
CD53 CD53 molecule 0.00708255
MAB21L2 mab-21-like 2 (C. elegans) 0.00706006
LRRN3 leucine rich repeat neuronal 3 0.00698996
GYPC glycophorin C (Gerbich blood group) 0.00697544
CA12 carbonic anhydrase XII 0.00696484
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.00694782
CFD complement factor D (adipsin) 0.00693987
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00693374
MT1HL1 metallothionein 1H-like 1 0.00692867
XPO7 exportin 7 0.00692108
EFNA5 ephrin-A5 0.00690994
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.00690059
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00689826
LYPD3 LY6/PLAUR domain containing 3 0.00687272
KLK10 kallikrein-related peptidase 10 0.00685516
COL15A1 collagen, type XV, alpha 1 0.0068535
KRT6B keratin 6B, type II 0.00682352
CD248 CD248 molecule, endosialin 0.00681483
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00681102
F3 coagulation factor III (thromboplastin, tissue factor) 0.00680808
NELL2 NEL-like 2 (chicken) 0.00677813
TUBB2A tubulin, beta 2A class IIa 0.00676539
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00674505
MT1H metallothionein 1H 0.00673907
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00672956
CHN1 chimerin 1 0.00668221
LOX lysyl oxidase 0.00668163
TWIST1 twist family bHLH transcription factor 1 0.00665105
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00662931
CIAO3 cytosolic iron-sulfur assembly component 3 0.00661484
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00660002
LAMA4 laminin, alpha 4 0.00657071
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.00656819
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00655371
TRIM29 tripartite motif containing 29 0.0065526
ETHE1 ethylmalonic encephalopathy 1 0.00650616
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00647306
CALML3 calmodulin-like 3 0.00646755
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00645872
L1CAM L1 cell adhesion molecule 0.00643182
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00641728
CD200 CD200 molecule 0.00641012
THBS2 thrombospondin 2 0.00640439
GIMAP4 GTPase, IMAP family member 4 0.0064032
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00639825
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00638459
NEFM neurofilament, medium polypeptide 0.00636472
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00634147
EFNA1 ephrin-A1 0.00633794
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00631599
KRT5 keratin 5, type II 0.00629923
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00629316
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00627348
NRCAM neuronal cell adhesion molecule 0.0062636
AHNAK2 AHNAK nucleoprotein 2 0.0062399
ISG20 interferon stimulated exonuclease gene 20kDa 0.00622938
RGS4 regulator of G-protein signaling 4 0.00620775
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.00620397
LPPR4 lipid phosphate phosphatase-related protein type 4 0.00620246
KRT23 keratin 23, type I 0.006197
PODXL podocalyxin-like 0.00618949
CST6 cystatin E/M 0.00618611
PCOLCE procollagen C-endopeptidase enhancer 0.00618578
PLEKHJ1 pleckstrin homology domain containing, family J member 1 0.00617938
GREM1 gremlin 1, DAN family BMP antagonist 0.00616638
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.00616366
AIM2 absent in melanoma 2 0.00616182
SPRR1A small proline-rich protein 1A 0.00615817
F13A1 coagulation factor XIII, A1 polypeptide 0.00615294
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0061529
HOPX HOP homeobox 0.00615097
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00612195
PLAUR plasminogen activator, urokinase receptor 0.00609775
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.00608675
FNDC3B fibronectin type III domain containing 3B 0.0060753
KRT6A keratin 6A, type II 0.00606826
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00606489
THBD thrombomodulin 0.00604834
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.00603125
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00602583
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00599672
NID1 nidogen 1 0.00596693
TSPAN3 tetraspanin 3 0.00595497
MBD2 methyl-CpG binding domain protein 2 0.00595172
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00594729
VNN2 vanin 2 0.00593161
IRAK3 interleukin-1 receptor-associated kinase 3 0.00590022
NT5E 5'-nucleotidase, ecto (CD73) 0.00589181
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene 0.00588763
AKAP12 A kinase (PRKA) anchor protein 12 0.00587857
PDE8B phosphodiesterase 8B 0.00586857
RGS5 regulator of G-protein signaling 5 0.00586552
CXCL8 chemokine (C-X-C motif) ligand 8 0.00585579
EFNA3 ephrin-A3 0.0058365
ADAT1 adenosine deaminase, tRNA-specific 1 0.00583643
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.00583383
F12 coagulation factor XII (Hageman factor) 0.00580911
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00579989
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00579448
FGF1 fibroblast growth factor 1 (acidic) 0.00578876
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00578249
SMAD2 SMAD family member 2 0.00578038
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.0057689
MRPS16 mitochondrial ribosomal protein S16 0.00576323
KDSR 3-ketodihydrosphingosine reductase 0.00575302
PPA1 pyrophosphatase (inorganic) 1 0.00574789
LY96 lymphocyte antigen 96 0.00574332
GUCY2C guanylate cyclase 2C 0.00572356
STMN2 stathmin 2 0.00571966
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00568804
CRABP2 cellular retinoic acid binding protein 2 0.00565854
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00563532
PDZK1IP1 PDZK1 interacting protein 1 0.00563372
GIMAP6 GTPase, IMAP family member 6 0.00562872
SCN3B sodium channel, voltage gated, type III beta subunit 0.00561815
SDC2 syndecan 2 0.00561594
THY1 Thy-1 cell surface antigen 0.00560496
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00559814
MFAP5 microfibrillar associated protein 5 0.00559555
MEN1 multiple endocrine neoplasia I 0.00558006
INHBB inhibin, beta B 0.00557671
FRZB frizzled-related protein 0.00556742
LPAR6 lysophosphatidic acid receptor 6 0.00556272
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00555733
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00555254
PELI1 pellino E3 ubiquitin protein ligase 1 0.00554313
MRPL19 mitochondrial ribosomal protein L19 0.00553839
TXNL1 thioredoxin-like 1 0.00553448
MDFIC MyoD family inhibitor domain containing 0.00550761
SPARCL1 SPARC-like 1 (hevin) 0.0054989
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00548734
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.00548565
MAP2K6 mitogen-activated protein kinase kinase 6 0.00547981
DEFB1 defensin, beta 1 0.00546905
GNLY granulysin 0.00545473
CLCA4 chloride channel accessory 4 0.00544511
PGAP3 post-GPI attachment to proteins 3 0.00544383
CADM1 cell adhesion molecule 1 0.00541728
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00541591
HLA-DOB major histocompatibility complex, class II, DO beta 0.00541256
NINJ1 ninjurin 1 0.00540268
PLVAP plasmalemma vesicle associated protein 0.00540052
CXCL12 chemokine (C-X-C motif) ligand 12 0.00539319
FKBP5 FK506 binding protein 5 0.00538973
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00538387
HCRT hypocretin (orexin) neuropeptide precursor 0.00538019
SNAP25 synaptosomal-associated protein, 25kDa 0.00537679
FAR2 fatty acyl CoA reductase 2 0.0053753
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.0053703
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.00535838
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00534793
TRAF3IP2 TRAF3 interacting protein 2 0.00533171
FSD1 fibronectin type III and SPRY domain containing 1 0.00533111
GDF3 growth differentiation factor 3 0.00532987
DUOX2 dual oxidase 2 0.00532609
KARS1 lysyl-tRNA synthetase 1 0.00531454
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00531113
THEMIS2 thymocyte selection associated family member 2 0.00530346
CCL5 chemokine (C-C motif) ligand 5 0.00529291
LITAF lipopolysaccharide-induced TNF factor 0.00528719
DSP desmoplakin 0.00528497

decreased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 -0.0164547
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0140706
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0129631
PDGFC platelet derived growth factor C -0.0126661
ANXA3 annexin A3 -0.0124287
CD9 CD9 molecule -0.0123005
TSPAN8 tetraspanin 8 -0.011858
MAP7 microtubule-associated protein 7 -0.0115506
MAGED1 melanoma antigen family D1 -0.0115334
PRKCZ protein kinase C, zeta -0.0113157
CRISP3 cysteine-rich secretory protein 3 -0.0110934
NOTCH2 notch 2 -0.0109687
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0108648
STK26 serine/threonine protein kinase 26 -0.0108188
ZBTB18 zinc finger and BTB domain containing 18 -0.0105736
LEF1 lymphoid enhancer-binding factor 1 -0.0104797
TPSAB1 tryptase alpha/beta 1 -0.010415
CTSZ cathepsin Z -0.0103369
ELN elastin -0.0101672
KRT19 keratin 19, type I -0.010111
PHACTR2 phosphatase and actin regulator 2 -0.0100364
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0100297
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00987825
AUTS2 autism susceptibility candidate 2 -0.00967075
MYO5C myosin VC -0.00952702
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.0094898
TACSTD2 tumor-associated calcium signal transducer 2 -0.00942755
SMAD7 SMAD family member 7 -0.00938645
NOTCH2NL notch 2 N-terminal like -0.00923237
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00921421
IRX5 iroquois homeobox 5 -0.00908404
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00907645
STK38 serine/threonine kinase 38 -0.0088542
MET MET proto-oncogene, receptor tyrosine kinase -0.00880606
G0S2 G0/G1 switch 2 -0.00869848
PFKM phosphofructokinase, muscle -0.00861043
KAZN kazrin, periplakin interacting protein -0.00856141
PLAAT3 phospholipase A and acyltransferase 3 -0.00854495
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00850629
CPB1 carboxypeptidase B1 (tissue) -0.00848845
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00839358
NAV3 neuron navigator 3 -0.00826719
ANKRD10 ankyrin repeat domain 10 -0.00816933
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00808587
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00808038
HMGB1 high mobility group box 1 -0.00806077
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00797956
RIT1 Ras-like without CAAX 1 -0.0078841
ZSCAN18 zinc finger and SCAN domain containing 18 -0.0077926
CALCA calcitonin-related polypeptide alpha -0.00774565
SIX1 SIX homeobox 1 -0.00760483
NBPF10 neuroblastoma breakpoint family, member 10 -0.00759788
TTC39A tetratricopeptide repeat domain 39A -0.00759744
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00758983
MSMB microseminoprotein, beta- -0.00756466
PLBD1 phospholipase B domain containing 1 -0.00755274
SC5D sterol-C5-desaturase -0.00754327
CREB1 cAMP responsive element binding protein 1 -0.00753195
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00740464
QPCT glutaminyl-peptide cyclotransferase -0.00737467
SIRT3 sirtuin 3 -0.00736275
PCP4 Purkinje cell protein 4 -0.00732406
NXN nucleoredoxin -0.00727682
AKR1C3 aldo-keto reductase family 1, member C3 -0.00727192
CTBP2 C-terminal binding protein 2 -0.00723994
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0071344
NPY neuropeptide Y -0.00711585
DBF4 DBF4 zinc finger -0.00707796
NUMA1 nuclear mitotic apparatus protein 1 -0.00707131
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00706949
SSBP2 single-stranded DNA binding protein 2 -0.00706481
CD81 CD81 molecule -0.00705818
RXRA retinoid X receptor, alpha -0.0070571
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00704835
KIF5B kinesin family member 5B -0.00703633
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00700207
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00698823
PKD2 polycystic kidney disease 2 (autosomal dominant) -0.00694743
CTH cystathionine gamma-lyase -0.00688518
REEP1 receptor accessory protein 1 -0.00687883
GRSF1 G-rich RNA sequence binding factor 1 -0.00672357
PRDX2 peroxiredoxin 2 -0.00670804
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -0.00669349
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00668412
RHOBTB3 Rho-related BTB domain containing 3 -0.00668202
S100A11 S100 calcium binding protein A11 -0.00668065
DYNLL1 dynein, light chain, LC8-type 1 -0.00665933
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00665811
CLGN calmegin -0.00665219
EFNB2 ephrin-B2 -0.00663991
TRRAP transformation/transcription domain-associated protein -0.0066346
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.00662177
TSPAN12 tetraspanin 12 -0.00661336
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -0.00660403
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00660015
TSPYL5 TSPY-like 5 -0.00658567
MSL2 male-specific lethal 2 homolog (Drosophila) -0.00658342
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.00654874
KANK2 KN motif and ankyrin repeat domains 2 -0.00654516
SPRY2 sprouty homolog 2 (Drosophila) -0.00647884
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00646406
JMJD6 jumonji domain containing 6 -0.00646385
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.00642313
MLPH melanophilin -0.00639762
HMGN3 high mobility group nucleosomal binding domain 3 -0.00639227
S100P S100 calcium binding protein P -0.00638682
ARHGAP22 Rho GTPase activating protein 22 -0.0063858
BASP1 brain abundant, membrane attached signal protein 1 -0.00632157
MAGEB2 melanoma antigen family B2 -0.0063102
TFPI2 tissue factor pathway inhibitor 2 -0.00630282
NYNRIN NYN domain and retroviral integrase containing -0.00629743
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00629629
TSPYL1 TSPY-like 1 -0.00625049
DEPTOR DEP domain containing MTOR-interacting protein -0.00624502
SOAT1 sterol O-acyltransferase 1 -0.00623128
MPRIP myosin phosphatase Rho interacting protein -0.00622328
EDRF1 erythroid differentiation regulatory factor 1 -0.00622184
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.00621346
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00617511
MYO6 myosin VI -0.00614478
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00612702
KLK2 kallikrein-related peptidase 2 -0.00612048
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00611918
NINJ2 ninjurin 2 -0.0061082
GPX3 glutathione peroxidase 3 -0.0060959
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -0.00609264
SUCO SUN domain containing ossification factor -0.00608933
PRUNE2 prune homolog 2 (Drosophila) -0.00608549
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.00607551
PILRB paired immunoglobin-like type 2 receptor beta -0.00606159
GATA6 GATA binding protein 6 -0.00602649
CCNG2 cyclin G2 -0.00602272
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0060163
KMT5B lysine methyltransferase 5B -0.00598168
GSTA4 glutathione S-transferase alpha 4 -0.00597769
NPC2 Niemann-Pick disease, type C2 -0.00594547
FGFR3 fibroblast growth factor receptor 3 -0.00592947
CIT citron rho-interacting serine/threonine kinase -0.00592706
CCND2 cyclin D2 -0.00590632
MAP9 microtubule-associated protein 9 -0.00589165
UGCG UDP-glucose ceramide glucosyltransferase -0.00589085
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00588891
NKTR natural killer cell triggering receptor -0.00588032
SRSF7 serine/arginine-rich splicing factor 7 -0.00588019
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00586798
SMG7 SMG7 nonsense mediated mRNA decay factor -0.00583654
CHKB choline kinase beta -0.00581182
ECHDC2 enoyl CoA hydratase domain containing 2 -0.005805
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00578285
TUBGCP3 tubulin, gamma complex associated protein 3 -0.00578106
SLC44A4 solute carrier family 44, member 4 -0.00577305
NADK NAD kinase -0.00576518
EML3 echinoderm microtubule associated protein like 3 -0.00574132
NISCH nischarin -0.00571219
UBP1 upstream binding protein 1 (LBP-1a) -0.00569633
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.00569074
SFRP4 secreted frizzled-related protein 4 -0.00568128
TRIB2 tribbles pseudokinase 2 -0.00565044
TUG1 taurine up-regulated 1 (non-protein coding) -0.00563527
TRIM37 tripartite motif containing 37 -0.00563092
TRIO trio Rho guanine nucleotide exchange factor -0.00561429
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00561176
THAP9-AS1 THAP9 antisense RNA 1 -0.00560014
PEG10 paternally expressed 10 -0.00559731
CDC20 cell division cycle 20 -0.00559107
RETREG2 reticulophagy regulator family member 2 -0.00558076
ADD1 adducin 1 (alpha) -0.00556453
RRBP1 ribosome binding protein 1 -0.00553404
DVL1 dishevelled segment polarity protein 1 -0.00553058
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00552211
MTCL1 microtubule crosslinking factor 1 -0.00552108
SQLE squalene epoxidase -0.00551794
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00550643
CDK8 cyclin-dependent kinase 8 -0.00549212
TBC1D16 TBC1 domain family, member 16 -0.0054738
CCDC92 coiled-coil domain containing 92 -0.00546853
HSPA4L heat shock 70kDa protein 4-like -0.00544483
CAPN1 calpain 1, (mu/I) large subunit -0.00544338
HIST1H2BK histone cluster 1, H2bk -0.00543958
C2CD2 C2 calcium-dependent domain containing 2 -0.00543443
OAT ornithine aminotransferase -0.00542367
DIXDC1 DIX domain containing 1 -0.00542039
RAB8A RAB8A, member RAS oncogene family -0.00541974
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.00541677
SRRT serrate, RNA effector molecule -0.00541639
NECTIN3 nectin cell adhesion molecule 3 -0.00540996
HMGB3 high mobility group box 3 -0.00539247
S100A4 S100 calcium binding protein A4 -0.0053784
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -0.00536758
SEC16A SEC16 homolog A (S. cerevisiae) -0.00536651
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00536067
CST3 cystatin C -0.00536004
FIP1L1 factor interacting with PAPOLA and CPSF1 -0.00535163
SH3BP4 SH3-domain binding protein 4 -0.00533474
IRF4 interferon regulatory factor 4 -0.00532888
ARGLU1 arginine and glutamate rich 1 -0.00532443
TPD52L1 tumor protein D52-like 1 -0.00532175
ARHGAP29 Rho GTPase activating protein 29 -0.0053131
ATG4B autophagy related 4B, cysteine peptidase -0.00531299
GSTT1 glutathione S-transferase theta 1 -0.00531147
NDNF neuron-derived neurotrophic factor -0.00530932
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -0.00530224
FBXL5 F-box and leucine-rich repeat protein 5 -0.00529773
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -0.00529518
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00529029
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00528761
CRY1 cryptochrome circadian clock 1 -0.00528653
NPY1R neuropeptide Y receptor Y1 -0.00526887
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00526852
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00526066
PLCB4 phospholipase C, beta 4 -0.00525741
TFAM transcription factor A, mitochondrial -0.00525183
PSPH phosphoserine phosphatase -0.00524368
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -0.00523323
TJP2 tight junction protein 2 -0.00523182
DPF2 D4, zinc and double PHD fingers family 2 -0.00522504
GSAP gamma-secretase activating protein -0.00521159
GATA2 GATA binding protein 2 -0.00519808
GCLC glutamate-cysteine ligase, catalytic subunit -0.0051923
RAD23B RAD23 homolog B (S. cerevisiae) -0.00517821
YME1L1 YME1-like 1 ATPase -0.00516032
IFRD1 interferon-related developmental regulator 1 -0.00515761
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00515291
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00515167
CCL19 chemokine (C-C motif) ligand 19 -0.0051451
TULP4 tubby like protein 4 -0.00514373
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00514025
GPSM2 G-protein signaling modulator 2 -0.00512991
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.00512162
DACH1 dachshund family transcription factor 1 -0.00512125
HDC histidine decarboxylase -0.0050972
CUX1 cut-like homeobox 1 -0.00508964
P3H2 prolyl 3-hydroxylase 2 -0.00508798
LAMP1 lysosomal-associated membrane protein 1 -0.00507646
NEFH neurofilament, heavy polypeptide -0.00507607
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00507603
SIAH2 siah E3 ubiquitin protein ligase 2 -0.00506572
PIAS3 protein inhibitor of activated STAT, 3 -0.0050613
CNPY3 canopy FGF signaling regulator 3 -0.00504864
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.00504101
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00502892
CHKA choline kinase alpha -0.00501837
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00500858
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -0.00500857
SLIT2 slit homolog 2 (Drosophila) -0.00500541
TRMT5 tRNA methyltransferase 5 -0.00500149
H1-0 H1.0 linker histone -0.00499757
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00499336
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0049901