ITGB3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)|The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3690)
External Link http://www.ncbi.nlm.nih.gov/gene/3690
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Genes

103 interacting proteins for ITGB3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAM23 ADAM metallopeptidase domain 23
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPTL3 angiopoietin-like 3
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ARF6 ADP-ribosylation factor 6
CAPN1 calpain 1, (mu/I) large subunit
CD36 CD36 molecule (thrombospondin receptor)
CD47 CD47 molecule
CD9 CD9 molecule
CDC42 cell division cycle 42
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CIB1 calcium and integrin binding 1 (calmyrin)
COL1A2 collagen, type I, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL6A3 collagen, type VI, alpha 3
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF1 colony stimulating factor 1 (macrophage)
CTSG cathepsin G
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EPHA2 EPH receptor A2
EPS8 epidermal growth factor receptor pathway substrate 8
F11R F11 receptor
F2 coagulation factor II (thrombin)
FBLN2 fibulin 2
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FGA fibrinogen alpha chain
FGF2 fibroblast growth factor 2 (basic)
FGG fibrinogen gamma chain
FLNA filamin A, alpha
FLNB filamin B, beta
FN1 fibronectin 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GSN gelsolin
GULP1 GULP, engulfment adaptor PTB domain containing 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
ILK integrin-linked kinase
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
KDR kinase insert domain receptor
LAMA4 laminin, alpha 4
LRP1 low density lipoprotein receptor-related protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MYO10 myosin X
NID1 nidogen 1
NOV nephroblastoma overexpressed
NUMB numb homolog (Drosophila)
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITPNA phosphatidylinositol transfer protein, alpha
PPAP2B phosphatidic acid phosphatase type 2B
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PXN paxillin
RABGAP1 RAB GTPase activating protein 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RGS12 regulator of G-protein signaling 12
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOC ras homolog family member C
SHB Src homology 2 domain containing adaptor protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TLN1 talin 1
TNS2 tensin 2
UBQLN1 ubiquilin 1
VAV3 vav 3 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VTN vitronectin
VWF von Willebrand factor