ITGB5 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description integrin, beta 5| (NCBI Entrez Gene Database, 3693)
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Genes

312 genes differentially expressed following the ITGB5 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 2.85945
PDCD1LG2 programmed cell death 1 ligand 2 2.85945
SPATA46 spermatogenesis associated 46 2.85945
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.85945
MMP12 matrix metallopeptidase 12 2.85945
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 2.85945
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 2.85945
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.85945
ASB12 ankyrin repeat and SOCS box containing 12 2.85945
TPT1 tumor protein, translationally-controlled 1 2.85945
PRR4 proline rich 4 (lacrimal) 2.85945
TMEM156 transmembrane protein 156 2.85945
TBC1D10C TBC1 domain family, member 10C 2.85945
DUSP29 dual specificity phosphatase 29 2.85945
LTB lymphotoxin beta (TNF superfamily, member 3) 2.85945
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.85945
TMPRSS11F transmembrane protease, serine 11F 2.85945
C17ORF107 chromosome 17 open reading frame 107 2.85945
ZNF648 zinc finger protein 648 2.85945
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.85945
RGS8 regulator of G-protein signaling 8 2.85945
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 2.79068
FABP1 fatty acid binding protein 1, liver 2.79068
GPR75 G protein-coupled receptor 75 2.79068
NANOS2 nanos homolog 2 (Drosophila) 2.79068
CELF3 CUGBP, Elav-like family member 3 2.79068
ASPDH aspartate dehydrogenase domain containing 2.79068
FOXQ1 forkhead box Q1 2.79068
KNG1 kininogen 1 2.79068
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 2.79068
CD2 CD2 molecule 2.79068
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 2.79068
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 2.79068
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2.79068
HBM hemoglobin, mu 2.79068
RFX6 regulatory factor X, 6 2.79068
CD69 CD69 molecule 2.79068
BSX brain-specific homeobox 2.79068
TPSD1 tryptase delta 1 2.79068
SFTPB surfactant protein B 2.79068
WDR89 WD repeat domain 89 2.79068
EDDM3A epididymal protein 3A 2.79068
TNIP3 TNFAIP3 interacting protein 3 2.79068
SLC23A3 solute carrier family 23, member 3 2.79068
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.79068
RSPO3 R-spondin 3 2.79068
DSG4 desmoglein 4 2.79068
EPB42 erythrocyte membrane protein band 4.2 2.79068
GSTM5 glutathione S-transferase mu 5 2.79068
HES3 hes family bHLH transcription factor 3 2.79068
PCDHB7 protocadherin beta 7 2.79068
MYO1G myosin IG 2.79068
GPR6 G protein-coupled receptor 6 2.79068
CD300LF CD300 molecule-like family member f 2.79068
CLDN14 claudin 14 2.79068
GBP3 guanylate binding protein 3 2.79068
H3-5 H3.5 histone 2.79068
CCDC198 coiled-coil domain containing 198 2.79068
ANKRD40CL ANKRD40 C-terminal like 2.79068
CATSPERZ catsper channel auxiliary subunit zeta 2.79068
SEPTIN12 septin 12 2.79068
EZHIP EZH inhibitory protein 2.79068
LHFPL7 LHFPL tetraspan subfamily member 7 2.79068
SMIM43 small integral membrane protein 43 2.79068
GNG5B G protein subunit gamma 5B 2.79068
H2BK1 H2B.K variant histone 1 2.79068
C1ORF232 chromosome 1 open reading frame 230 2.79068
NOTCH2NLB notch 2 N-terminal like B 2.79068
REELD1 reeler domain containing 1 2.79068
ANKRD42-DT ANKRD42 divergent transcript 2.79068
FOXN4 forkhead box N4 2.79068
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 2.79068
WEE2 WEE1 homolog 2 (S. pombe) 2.79068
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.79068
ATP13A2 ATPase type 13A2 2.79068
PTPRC protein tyrosine phosphatase, receptor type, C 2.79068
ITK IL2-inducible T-cell kinase 2.79068
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 2.79068
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2.79068
TEKTL1 tektin like 1 2.79068
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 2.79068
SAMD15 sterile alpha motif domain containing 15 2.79068
OR2D2 olfactory receptor, family 2, subfamily D, member 2 2.79068
OR13H1 olfactory receptor, family 13, subfamily H, member 1 2.79068
GATA5 GATA binding protein 5 2.79068
F5 coagulation factor V (proaccelerin, labile factor) 2.79068
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 2.79068
MIOX myo-inositol oxygenase 2.79068
TMPRSS6 transmembrane protease, serine 6 2.79068
SMIM32 small integral membrane protein 32 2.79068
SOWAHA sosondowah ankyrin repeat domain family member A 2.79068
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.79068
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.79068
ISL1 ISL LIM homeobox 1 2.79068
MAPK11 mitogen-activated protein kinase 11 2.79068
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.79068
NUTM2D NUT family member 2D 2.79068
IL1B interleukin 1, beta 2.79068
FAM219A family with sequence similarity 219, member A 2.79068
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 2.79068
GPR45 G protein-coupled receptor 45 2.79068
ZCCHC12 zinc finger, CCHC domain containing 12 2.79068
FGF17 fibroblast growth factor 17 2.79068
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 2.79068
PDCD2 programmed cell death 2 2.79068
KRT15 keratin 15, type I 2.79068
LRTM2 leucine-rich repeats and transmembrane domains 2 2.79068
DQX1 DEAQ box RNA-dependent ATPase 1 2.79068
GP1BB glycoprotein Ib (platelet), beta polypeptide 2.79068
FATE1 fetal and adult testis expressed 1 2.79068
AQP6 aquaporin 6, kidney specific 2.79068
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.79068
RNASE13 ribonuclease, RNase A family, 13 (non-active) 2.79068
PRM2 protamine 2 2.79068
ZNF735 zinc finger protein 735 2.79068
SLC36A3 solute carrier family 36, member 3 2.79068
DRD2 dopamine receptor D2 2.79068
PMP2 peripheral myelin protein 2 2.79068
AQP1 aquaporin 1 (Colton blood group) 2.79068
RHAG Rh-associated glycoprotein 2.79068
TEX12 testis expressed 12 2.79068
MYOZ2 myozenin 2 2.79068
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.79068
NLRP6 NLR family, pyrin domain containing 6 2.79068
BTBD16 BTB (POZ) domain containing 16 2.79068
GJB6 gap junction protein, beta 6, 30kDa 2.79068
RNASE9 ribonuclease, RNase A family, 9 (non-active) 2.79068
WNT2 wingless-type MMTV integration site family member 2 2.79068
STAP1 signal transducing adaptor family member 1 2.79068
CLEC18B C-type lectin domain family 18, member B 2.79068
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.79068
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 2.79068
NPY2R neuropeptide Y receptor Y2 2.79068
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 2.79068
RP1 retinitis pigmentosa 1 (autosomal dominant) 2.79068
GRAP2 GRB2-related adaptor protein 2 2.79068
LRRC15 leucine rich repeat containing 15 2.79068
PRR35 proline rich 35 2.79068
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 2.79068
ZC3H12D zinc finger CCCH-type containing 12D 2.79068
DLX2 distal-less homeobox 2 2.79068
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 2.79068
GPR61 G protein-coupled receptor 61 2.79068
ALLC allantoicase 2.79068
TRIM7 tripartite motif containing 7 2.79068
ADRA1B adrenoceptor alpha 1B 2.79068
TAS2R46 taste receptor, type 2, member 46 2.79068
CHAT choline O-acetyltransferase 2.79068
STAG2 stromal antigen 2 2.74888
ZAN zonadhesin (gene/pseudogene) 2.7369
C11ORF86 chromosome 11 open reading frame 86 2.7369
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 2.68894
HDGFL3 HDGF like 3 2.68894
ERBB2 erb-b2 receptor tyrosine kinase 2 2.63751
PHF13 PHD finger protein 13 2.62733
ATG14 autophagy related 14 2.58743
KBTBD12 kelch repeat and BTB (POZ) domain containing 12 2.48365
CLN3 ceroid-lipofuscinosis, neuronal 3 2.43149
KLHL4 kelch-like family member 4 2.42806
NT5C2 5'-nucleotidase, cytosolic II 2.40531
PSKH2 protein serine kinase H2 2.4037
EHMT1 euchromatic histone-lysine N-methyltransferase 1 2.4037
ERAS ES cell expressed Ras 2.4037
CLTC clathrin, heavy chain (Hc) 2.39091
CBX5 chromobox homolog 5 2.37659
TRUB2 TruB pseudouridine (psi) synthase family member 2 2.36575
PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 2.34753
MRLN myoregulin 2.31854
STRN striatin, calmodulin binding protein 2.30925
MOK MOK protein kinase 2.30002
ASXL3 additional sex combs like transcriptional regulator 3 2.29913
NDUFAF8 NADH:ubiquinone oxidoreductase complex assembly factor 8 2.27497
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 2.24189
C19ORF84 chromosome 19 open reading frame 84 2.23914
ZNF326 zinc finger protein 326 2.23914
TUBB4A tubulin, beta 4A class IVa 2.23914
CCNC cyclin C 2.23914
ZPR1 ZPR1 zinc finger 2.23047
UBE2D3 ubiquitin-conjugating enzyme E2D 3 2.20415
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.19909
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 2.1791
TUBB tubulin, beta class I 2.17874
GANAB glucosidase, alpha; neutral AB 2.14014
RUFY2 RUN and FYVE domain containing 2 2.14014
CRYBG1 crystallin beta-gamma domain containing 1 2.13979
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 2.12534
FYTTD1 forty-two-three domain containing 1 2.11258
NUBP1 nucleotide binding protein 1 2.10703
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 2.09945
PFDN4 prefoldin subunit 4 2.09909
AGO4 argonaute RISC catalytic component 4 2.09558
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.09431
GPX4 glutathione peroxidase 4 2.09158
HAPLN3 hyaluronan and proteoglycan link protein 3 2.05881
SF1 splicing factor 1 2.0447
RBM46 RNA binding motif protein 46 2.03694
C1QTNF6 C1q and tumor necrosis factor related protein 6 2.03694
PRELID2 PRELI domain containing 2 2.03395
KATNAL2 katanin p60 subunit A-like 2 2.0318
ARHGAP18 Rho GTPase activating protein 18 2.02991
CLTA clathrin, light chain A 2.00345
BCDIN3D BCDIN3 domain containing 2.00065

decreased expression

Symbol Name Standardized Value
ZNF441 zinc finger protein 441 -2.85945
ANKRD65 ankyrin repeat domain 65 -2.85945
POC1B-DUSP6 POC1B-DUSP6 readthrough -2.85945
SP100 SP100 nuclear antigen -2.85945
GH2 growth hormone 2 -2.85945
SH3TC2 SH3 domain and tetratricopeptide repeats 2 -2.85945
MGAM2 maltase-glucoamylase 2 (putative) -2.79068
ATXN7L2 ataxin 7-like 2 -2.79068
PGBDF plakoglobin binding and degradation factor -2.79068
PLA2G4D phospholipase A2, group IVD (cytosolic) -2.79068
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.79068
ARSF arylsulfatase F -2.79068
CD68 CD68 molecule -2.79068
OR6B1 olfactory receptor, family 6, subfamily B, member 1 -2.79068
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 -2.79068
ACKR2 atypical chemokine receptor 2 -2.79068
ANXA1 annexin A1 -2.79068
HEATR9 HEAT repeat containing 9 -2.79068
COL20A1 collagen, type XX, alpha 1 -2.79068
SIX3 SIX homeobox 3 -2.79068
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) -2.79068
C17ORF113 chromosome 17 open reading frame 113 -2.79068
ABLIM3 actin binding LIM protein family, member 3 -2.79068
BHMT betaine--homocysteine S-methyltransferase -2.79068
CIMAP1B ciliary microtubule associated protein 1B -2.79068
TEX29 testis expressed 29 -2.79068
GOLGA8K golgin A8 family, member K -2.79068
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein -2.79068
CD8A CD8a molecule -2.79068
CHUK conserved helix-loop-helix ubiquitous kinase -2.79068
STARD6 StAR-related lipid transfer (START) domain containing 6 -2.79068
CATIP ciliogenesis associated TTC17 interacting protein -2.79068
ABHD15 abhydrolase domain containing 15 -2.79068
MOS v-mos Moloney murine sarcoma viral oncogene homolog -2.79068
CAPN9 calpain 9 -2.79068
ZNF184 zinc finger protein 184 -2.77609
MRPL52 mitochondrial ribosomal protein L52 -2.73178
MRPL53 mitochondrial ribosomal protein L53 -2.72073
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -2.72073
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 -2.72073
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -2.68894
ADGRB3 adhesion G protein-coupled receptor B3 -2.68894
SMG6 SMG6 nonsense mediated mRNA decay factor -2.67186
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit -2.58632
NEB nebulin -2.55692
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -2.53561
GNG8 guanine nucleotide binding protein (G protein), gamma 8 -2.53561
PABPC4L poly(A) binding protein, cytoplasmic 4-like -2.51038
SKIL SKI-like proto-oncogene -2.49114
GRM5 glutamate receptor, metabotropic 5 -2.48365
AZIN2 antizyme inhibitor 2 -2.45327
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -2.45327
SPACDR sperm acrosome developmental regulator -2.45327
CNR1 cannabinoid receptor 1 (brain) -2.45327
NLE1 notchless homolog 1 (Drosophila) -2.45228
ITGB5 integrin, beta 5 -2.44918
TMEM68 transmembrane protein 68 -2.44695
MYRFL myelin regulatory factor-like -2.42091
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 -2.4037
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -2.4037
DAZL deleted in azoospermia-like -2.4037
PPAT phosphoribosyl pyrophosphate amidotransferase -2.4037
H2AC7 H2A clustered histone 7 -2.4037
C7orf78 chromosome 7 open reading frame 78 -2.38878
LRRC27 leucine rich repeat containing 27 -2.37157
CDKL3 cyclin-dependent kinase-like 3 -2.36788
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -2.35477
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -2.34753
ZNF721 zinc finger protein 721 -2.31854
POLL polymerase (DNA directed), lambda -2.30754
GLIPR1L1 GLI pathogenesis-related 1 like 1 -2.30754
CAMTA2 calmodulin binding transcription activator 2 -2.30002
DDB2 damage-specific DNA binding protein 2, 48kDa -2.29119
L3MBTL3 l(3)mbt-like 3 (Drosophila) -2.25124
DPPA3 developmental pluripotency associated 3 -2.24219
RASL10A RAS-like, family 10, member A -2.24219
TMEM215 transmembrane protein 215 -2.24219
LEFTY2 left-right determination factor 2 -2.24219
PLCG1 phospholipase C, gamma 1 -2.23404
FMNL2 formin-like 2 -2.23047
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 -2.20298
SFRP4 secreted frizzled-related protein 4 -2.19937
PC pyruvate carboxylase -2.19937
TOMM70 translocase of outer mitochondrial membrane 70 -2.1791
NUP35 nucleoporin 35kDa -2.16391
FGF13 fibroblast growth factor 13 -2.16301
INSL6 insulin-like 6 -2.15607
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.14014
BRD2 bromodomain containing 2 -2.13841
ZBTB22 zinc finger and BTB domain containing 22 -2.1376
AK7 adenylate kinase 7 -2.1279
RAB9A RAB9A, member RAS oncogene family -2.10889
DAPK3 death-associated protein kinase 3 -2.10889
GIGYF2 GRB10 interacting GYF protein 2 -2.10889
HAUS3 HAUS augmin-like complex, subunit 3 -2.10889
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -2.10889
RTL8A retrotransposon Gag like 8A -2.09158
DTX4 deltex 4, E3 ubiquitin ligase -2.0679
GMPR guanosine monophosphate reductase -2.0679
PTBP2 polypyrimidine tract binding protein 2 -2.06367
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.05443
CUL4A cullin 4A -2.05314
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.04145
ATOSA atos homolog A -2.03694
COL11A1 collagen, type XI, alpha 1 -2.03395
GKAP1 G kinase anchoring protein 1 -2.02991
IRAG1 inositol 1,4,5-triphosphate receptor associated 1 -2.02811
YTHDC1 YTH domain containing 1 -2.02062
ANKRD7 ankyrin repeat domain 7 -2.01712
DNM1 dynamin 1 -2.00345