ITGB6 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description integrin, beta 6|This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 3694)
External Link http://www.ncbi.nlm.nih.gov/gene/3694
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Genes

13 interacting proteins for ITGB6 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
FHL2 four and a half LIM domains 2
FLNA filamin A, alpha
FLNB filamin B, beta
FN1 fibronectin 1
FYN FYN proto-oncogene, Src family tyrosine kinase
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
MAPK1 mitogen-activated protein kinase 1
SPP1 secreted phosphoprotein 1
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TNC tenascin C
VTN vitronectin