ITK_knockout_241_GSE12465 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE12465
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Genes

600 genes differentially expressed following the ITK_knockout_241_GSE12465 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
ATF7IP activating transcription factor 7 interacting protein 5.14249
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 3.66741
TMEM106C transmembrane protein 106C 3.5152
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 3.38913
MTDH metadherin 2.96376
ZBTB42 zinc finger and BTB domain containing 42 2.91961
MAPK10 mitogen-activated protein kinase 10 2.89176
CSNK1D casein kinase 1, delta 2.78421
TMEM238 transmembrane protein 238 2.73901
BRCA1 breast cancer 1, early onset 2.70995
FADD Fas (TNFRSF6)-associated via death domain 2.67325
BOC BOC cell adhesion associated, oncogene regulated 2.6425
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 2.61309
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 2.57885
FOXN1 forkhead box N1 2.57217
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.5384
GSTP1 glutathione S-transferase pi 1 2.51901
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.50719
SSR1 signal sequence receptor, alpha 2.48052
GNA14 guanine nucleotide binding protein (G protein), alpha 14 2.46224
PCDH1 protocadherin 1 2.44737
RAB3D RAB3D, member RAS oncogene family 2.41758
SCN4A sodium channel, voltage gated, type IV alpha subunit 2.41642
ABHD17B abhydrolase domain containing 17B 2.41454
CLEC16A C-type lectin domain family 16, member A 2.40237
CD44 CD44 molecule (Indian blood group) 2.39699
NR2F6 nuclear receptor subfamily 2, group F, member 6 2.37857
ZIC1 Zic family member 1 2.32957
NSF N-ethylmaleimide-sensitive factor 2.31964
ABHD3 abhydrolase domain containing 3 2.31347
DXO decapping exoribonuclease 2.30815
PKP2 plakophilin 2 2.30439
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 2.28812
C5ORF34 chromosome 5 open reading frame 34 2.28489
TOLLIP toll interacting protein 2.27889
COPS7B COP9 signalosome subunit 7B 2.26305
ISCA2 iron-sulfur cluster assembly 2 2.26125
NFIA nuclear factor I/A 2.25626
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.25438
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.24777
KIF18B kinesin family member 18B 2.24387
FBXL17 F-box and leucine-rich repeat protein 17 2.21717
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 2.21261
SOX15 SRY (sex determining region Y)-box 15 2.19296
ODF4 outer dense fiber of sperm tails 4 2.17836
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 2.16778
SLC45A4 solute carrier family 45, member 4 2.1527
PDE4A phosphodiesterase 4A, cAMP-specific 2.15216
RFESD Rieske (Fe-S) domain containing 2.14708
CCDC116 coiled-coil domain containing 116 2.14367
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 2.12483
CD38 CD38 molecule 2.11236
DENND1A DENN/MADD domain containing 1A 2.11051
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase 2.10803
SLC22A24 solute carrier family 22, member 24 2.0967
GSAP gamma-secretase activating protein 2.0862
PPP1R15B protein phosphatase 1, regulatory subunit 15B 2.07374
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 2.04099
LPAR2 lysophosphatidic acid receptor 2 2.04
AGO4 argonaute RISC catalytic component 4 2.03216
PDZD11 PDZ domain containing 11 2.01657
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 1.99631
CCDC28B coiled-coil domain containing 28B 1.97632
FAM98B family with sequence similarity 98, member B 1.93784
ARPC5L actin related protein 2/3 complex, subunit 5-like 1.93114
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.92862
ZFYVE19 zinc finger, FYVE domain containing 19 1.92827
ZNF462 zinc finger protein 462 1.9229
COL9A1 collagen, type IX, alpha 1 1.92179
CENPO centromere protein O 1.91762
WWP1 WW domain containing E3 ubiquitin protein ligase 1 1.91728
TRAIP TRAF interacting protein 1.90037
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 1.88624
CXCL3 chemokine (C-X-C motif) ligand 3 1.8802
SHFM1 split hand/foot malformation (ectrodactyly) type 1 1.8598
HSPA2 heat shock 70kDa protein 2 1.85453
MID2 midline 2 1.8529
DCN decorin 1.8481
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.84524
DTX3 deltex 3, E3 ubiquitin ligase 1.84325
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 1.83964
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.82824
TRABD TraB domain containing 1.82789
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 1.82536
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.82203
DNASE1L3 deoxyribonuclease I-like 3 1.819
LAMP1 lysosomal-associated membrane protein 1 1.80748
MEGF8 multiple EGF-like-domains 8 1.807
LPPR1 lipid phosphate phosphatase-related protein type 1 1.80484
LCA5L Leber congenital amaurosis 5-like 1.79494
CCDC77 coiled-coil domain containing 77 1.79353
C3ORF18 chromosome 3 open reading frame 18 1.79351
LSM12 LSM12 homolog (S. cerevisiae) 1.78617
GLYCTK glycerate kinase 1.78324
ATAT1 alpha tubulin acetyltransferase 1 1.77722
GLS glutaminase 1.77576
RAD18 RAD18 E3 ubiquitin protein ligase 1.77546
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 1.77525
POMP proteasome maturation protein 1.77407
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 1.77362
ATF6 activating transcription factor 6 1.76865
PLXDC2 plexin domain containing 2 1.76384
TMED8 transmembrane emp24 protein transport domain containing 8 1.76178
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 1.74195
DMGDH dimethylglycine dehydrogenase 1.73646
CFDP1 craniofacial development protein 1 1.73443
ERLIN2 ER lipid raft associated 2 1.73213
OTP orthopedia homeobox 1.72326
C16ORF91 chromosome 16 open reading frame 91 1.72203
KIF3C kinesin family member 3C 1.71975
RANBP17 RAN binding protein 17 1.70454
SPATA13 spermatogenesis associated 13 1.69686
ASB7 ankyrin repeat and SOCS box containing 7 1.68227
FGD6 FYVE, RhoGEF and PH domain containing 6 1.6644
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 1.65898
PRPF31 pre-mRNA processing factor 31 1.64815
PBLD phenazine biosynthesis-like protein domain containing 1.63844
C10ORF120 chromosome 10 open reading frame 120 1.62688
CLDN2 claudin 2 1.62603
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 1.61819
MRPL17 mitochondrial ribosomal protein L17 1.61808
RASGEF1A RasGEF domain family, member 1A 1.61643
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 1.61575
RAP2B RAP2B, member of RAS oncogene family 1.61518
PEX11A peroxisomal biogenesis factor 11 alpha 1.61225
TMEM190 transmembrane protein 190 1.60973
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 1.60305
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 1.59856
ADAM12 ADAM metallopeptidase domain 12 1.59205
KIF17 kinesin family member 17 1.58808
LOXL1 lysyl oxidase-like 1 1.58199
ACSL5 acyl-CoA synthetase long-chain family member 5 1.58141
DSC1 desmocollin 1 1.57982
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 1.57777
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 1.57688
BARD1 BRCA1 associated RING domain 1 1.57372
C17ORF75 chromosome 17 open reading frame 75 1.57013
NCEH1 neutral cholesterol ester hydrolase 1 1.55749
HPS1 Hermansky-Pudlak syndrome 1 1.55572
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 1.54978
CALB1 calbindin 1, 28kDa 1.54747
GOLGA7B golgin A7 family, member B 1.54592
TNK2 tyrosine kinase, non-receptor, 2 1.54562
PHF8 PHD finger protein 8 1.54081
KLF17 Kruppel-like factor 17 1.54057
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 1.5361
TFRC transferrin receptor 1.53603
WDFY3 WD repeat and FYVE domain containing 3 1.53315
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 1.53242
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.53044
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 1.52621
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 1.52216
C3ORF33 chromosome 3 open reading frame 33 1.51972
ZNF518B zinc finger protein 518B 1.51669
DSCAM Down syndrome cell adhesion molecule 1.51438
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.5112
FRS2 fibroblast growth factor receptor substrate 2 1.50968
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.50939
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 1.497
MATR3 matrin 3 1.49197
DPEP1 dipeptidase 1 (renal) 1.49133
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 1.49
LYPD4 LY6/PLAUR domain containing 4 1.48991
DOK7 docking protein 7 1.4891
C9ORF64 chromosome 9 open reading frame 64 1.48809
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 1.48451
BMP15 bone morphogenetic protein 15 1.47984
GNS glucosamine (N-acetyl)-6-sulfatase 1.47853
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 1.47798
TDRD7 tudor domain containing 7 1.47522
PTCRA pre T-cell antigen receptor alpha 1.4697
VARS2 valyl-tRNA synthetase 2, mitochondrial 1.4678
FBF1 Fas (TNFRSF6) binding factor 1 1.4672
HPN hepsin 1.46587
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 1.46462
HPS4 Hermansky-Pudlak syndrome 4 1.46343
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.45972
CCR2 chemokine (C-C motif) receptor 2 1.45689
SCGN secretagogin, EF-hand calcium binding protein 1.45576
USP30 ubiquitin specific peptidase 30 1.45445
TOX2 TOX high mobility group box family member 2 1.45364
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 1.45331
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 1.45123
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 1.45068
SEPHS1 selenophosphate synthetase 1 1.44744
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 1.44447
ARL15 ADP-ribosylation factor-like 15 1.44377
GALC galactosylceramidase 1.44152
TBX2 T-box 2 1.43642
WDR53 WD repeat domain 53 1.43499
KIAA0319L KIAA0319-like 1.43001
TPD52L2 tumor protein D52-like 2 1.42884
MRPL11 mitochondrial ribosomal protein L11 1.42857
MAPK15 mitogen-activated protein kinase 15 1.4251
BAG3 BCL2-associated athanogene 3 1.42435
PEX16 peroxisomal biogenesis factor 16 1.42429
ORC1 origin recognition complex, subunit 1 1.42212
SYNGR2 synaptogyrin 2 1.41928
UBQLN2 ubiquilin 2 1.4184
MRPL52 mitochondrial ribosomal protein L52 1.41713
RAP1GAP RAP1 GTPase activating protein 1.41557
GPRC6A G protein-coupled receptor, class C, group 6, member A 1.41463
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.41462
RECQL5 RecQ protein-like 5 1.41285
TJP3 tight junction protein 3 1.41079
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 1.40915
AKAP6 A kinase (PRKA) anchor protein 6 1.40297
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 1.39911
UBE4A ubiquitination factor E4A 1.39125
FKTN fukutin 1.38964
RGS12 regulator of G-protein signaling 12 1.38885
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 1.38619
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 1.38485
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.38481
PGK1 phosphoglycerate kinase 1 1.38315
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 1.38305
POFUT1 protein O-fucosyltransferase 1 1.3816
ZCCHC3 zinc finger, CCHC domain containing 3 1.37942
TCF20 transcription factor 20 (AR1) 1.37739
PTPRO protein tyrosine phosphatase, receptor type, O 1.37656
ACSM1 acyl-CoA synthetase medium-chain family member 1 1.37274
STOM stomatin 1.37257
RHOA ras homolog family member A 1.37145
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 1.36728
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 1.36625
REXO2 RNA exonuclease 2 1.366
FAM227B family with sequence similarity 227, member B 1.3634
RHOB ras homolog family member B 1.36167
STARD10 StAR-related lipid transfer (START) domain containing 10 1.36165
PEX14 peroxisomal biogenesis factor 14 1.35801
MYO1D myosin ID 1.35516
TMEM183A transmembrane protein 183A 1.35494
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 1.35294
UPK3A uroplakin 3A 1.35189
EFHD2 EF-hand domain family, member D2 1.34758
RYBP RING1 and YY1 binding protein 1.3466
C8ORF48 chromosome 8 open reading frame 48 1.34648
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 1.3463
FAM166A family with sequence similarity 166, member A 1.34396
LRRC20 leucine rich repeat containing 20 1.34131
NRDE2 NRDE-2, necessary for RNA interference, domain containing 1.34052
SLC22A15 solute carrier family 22, member 15 1.33977
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 1.33885
GNG11 guanine nucleotide binding protein (G protein), gamma 11 1.33804
RAD51D RAD51 paralog D 1.33787
UPK2 uroplakin 2 1.33454
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.33247
HYOU1 hypoxia up-regulated 1 1.33215
CD82 CD82 molecule 1.32991
AK2 adenylate kinase 2 1.32685
DGCR14 DiGeorge syndrome critical region gene 14 1.32602
ONECUT1 one cut homeobox 1 1.32557
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.32408
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.32396
RPUSD3 RNA pseudouridylate synthase domain containing 3 1.32262
RALBP1 ralA binding protein 1 1.32018
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.31715
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.3168
SPATA16 spermatogenesis associated 16 1.31611
SLC18B1 solute carrier family 18, subfamily B, member 1 1.31503
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 1.31484
E2F1 E2F transcription factor 1 1.31326
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.31306
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1.31155
CCL3L3 chemokine (C-C motif) ligand 3-like 3 1.30895
NOTCH3 notch 3 1.30713
HOXC8 homeobox C8 1.30708
PLK5 polo-like kinase 5 1.30669
PEX19 peroxisomal biogenesis factor 19 1.30074
METTL6 methyltransferase like 6 1.30024
TSPAN33 tetraspanin 33 1.29894
GATSL2 GATS protein-like 2 1.29888
ADORA3 adenosine A3 receptor 1.29884
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 1.2945
ANGPTL2 angiopoietin-like 2 1.29345
C14ORF80 chromosome 14 open reading frame 80 1.29241
RTN3 reticulon 3 1.28868
YIPF5 Yip1 domain family, member 5 1.28726
GLT8D1 glycosyltransferase 8 domain containing 1 1.28718
VRK1 vaccinia related kinase 1 1.28269
SLC39A9 solute carrier family 39, member 9 1.28099
THBS4 thrombospondin 4 1.27926
TSG101 tumor susceptibility 101 1.27784
INCENP inner centromere protein antigens 135/155kDa 1.27715
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.27363
JUND jun D proto-oncogene 1.27325
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 1.27275
KIAA1045 KIAA1045 1.27249
POSTN periostin, osteoblast specific factor 1.27077
TCP1 t-complex 1 1.26982
FAM126B family with sequence similarity 126, member B 1.26976
CDX1 caudal type homeobox 1 1.26937
ATXN7L3B ataxin 7-like 3B 1.26856
RBPMS RNA binding protein with multiple splicing 1.26792
FAM84A family with sequence similarity 84, member A 1.26686
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.26579
STX17 syntaxin 17 1.26499
EIF4A3 eukaryotic translation initiation factor 4A3 1.26475
NOV nephroblastoma overexpressed 1.26146
CFI complement factor I 1.25914

decreased expression

Symbol Name Standardized Value
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -3.26051
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -3.22927
INTS3 integrator complex subunit 3 -3.06413
CCDC47 coiled-coil domain containing 47 -2.96046
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -2.9566
NPC2 Niemann-Pick disease, type C2 -2.91165
ATG7 autophagy related 7 -2.872
TMEM123 transmembrane protein 123 -2.80994
LZTR1 leucine-zipper-like transcription regulator 1 -2.79882
TFB2M transcription factor B2, mitochondrial -2.75441
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -2.74647
ZNF672 zinc finger protein 672 -2.74213
SYNRG synergin, gamma -2.62143
MUC2 mucin 2, oligomeric mucus/gel-forming -2.61599
ZNF7 zinc finger protein 7 -2.60536
ZNF639 zinc finger protein 639 -2.60292
MTERF4 mitochondrial transcription termination factor 4 -2.60016
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.59873
JAKMIP1 janus kinase and microtubule interacting protein 1 -2.59705
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.57048
RPL28 ribosomal protein L28 -2.55387
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -2.50981
ASTE1 asteroid homolog 1 (Drosophila) -2.48503
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -2.45844
ARMCX2 armadillo repeat containing, X-linked 2 -2.43216
SMAD4 SMAD family member 4 -2.42966
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.40277
ENO4 enolase family member 4 -2.39987
ZNF260 zinc finger protein 260 -2.37003
PTTG1 pituitary tumor-transforming 1 -2.35615
LEF1 lymphoid enhancer-binding factor 1 -2.33707
RNF13 ring finger protein 13 -2.32753
EED embryonic ectoderm development -2.3085
MTFMT mitochondrial methionyl-tRNA formyltransferase -2.30275
MTPAP mitochondrial poly(A) polymerase -2.29126
TMEM175 transmembrane protein 175 -2.26178
SLAIN2 SLAIN motif family, member 2 -2.24543
FITM2 fat storage-inducing transmembrane protein 2 -2.23544
PCBP1 poly(rC) binding protein 1 -2.20342
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -2.19258
ANAPC1 anaphase promoting complex subunit 1 -2.187
RPS29 ribosomal protein S29 -2.18216
C17ORF58 chromosome 17 open reading frame 58 -2.17134
TADA2B transcriptional adaptor 2B -2.17079
GMPR2 guanosine monophosphate reductase 2 -2.14992
ZNF559-ZNF177 ZNF559-ZNF177 readthrough -2.12498
KLHL42 kelch-like family member 42 -2.11655
MFAP3 microfibrillar-associated protein 3 -2.11338
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -2.07178
SEC63 SEC63 homolog (S. cerevisiae) -2.04229
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -2.00893
VPS33B vacuolar protein sorting 33 homolog B (yeast) -2.00685
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -1.98052
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit -1.97394
LENG1 leukocyte receptor cluster (LRC) member 1 -1.97288
AZI2 5-azacytidine induced 2 -1.96545
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -1.96522
USP3 ubiquitin specific peptidase 3 -1.96468
MED20 mediator complex subunit 20 -1.96333
TXNDC16 thioredoxin domain containing 16 -1.96206
TRADD TNFRSF1A-associated via death domain -1.95568
ZC3H10 zinc finger CCCH-type containing 10 -1.9443
FAM65B family with sequence similarity 65, member B -1.94239
ARL16 ADP-ribosylation factor-like 16 -1.93895
RHOT1 ras homolog family member T1 -1.93397
TTPAL tocopherol (alpha) transfer protein-like -1.93381
PDF peptide deformylase (mitochondrial) -1.93144
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -1.92289
FBXO42 F-box protein 42 -1.90966
LMTK2 lemur tyrosine kinase 2 -1.89776
UBA1 ubiquitin-like modifier activating enzyme 1 -1.88705
MED17 mediator complex subunit 17 -1.86402
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -1.86034
IL6ST interleukin 6 signal transducer -1.858
ZNF644 zinc finger protein 644 -1.85686
ABT1 activator of basal transcription 1 -1.85564
RPL26 ribosomal protein L26 -1.84675
ITK IL2-inducible T-cell kinase -1.83926
KDM3A lysine (K)-specific demethylase 3A -1.8345
ATG4A autophagy related 4A, cysteine peptidase -1.82722
SIMC1 SUMO-interacting motifs containing 1 -1.8266
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -1.81676
TBCCD1 TBCC domain containing 1 -1.80206
PRKD2 protein kinase D2 -1.79441
PARP2 poly (ADP-ribose) polymerase 2 -1.78842
ANKLE2 ankyrin repeat and LEM domain containing 2 -1.7792
SMIM7 small integral membrane protein 7 -1.77544
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 -1.76904
PHTF1 putative homeodomain transcription factor 1 -1.7664
TNR tenascin R -1.76602
CCDC53 coiled-coil domain containing 53 -1.76278
MMP20 matrix metallopeptidase 20 -1.75882
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma -1.74607
IL17RA interleukin 17 receptor A -1.73859
C12ORF49 chromosome 12 open reading frame 49 -1.73777
EIF3H eukaryotic translation initiation factor 3, subunit H -1.73422
TMEM9B TMEM9 domain family, member B -1.72352
RHOH ras homolog family member H -1.72017
TRPV1 transient receptor potential cation channel, subfamily V, member 1 -1.70632
ATG13 autophagy related 13 -1.7053
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -1.70527
CEP63 centrosomal protein 63kDa -1.70296
MAP2K5 mitogen-activated protein kinase kinase 5 -1.69646
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.69453
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -1.69316
ZNF142 zinc finger protein 142 -1.68999
EVX1 even-skipped homeobox 1 -1.6858
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -1.67883
MITD1 MIT, microtubule interacting and transport, domain containing 1 -1.67102
ZNF606 zinc finger protein 606 -1.67007
RPS11 ribosomal protein S11 -1.65978
ZNF319 zinc finger protein 319 -1.65238
NLRP9 NLR family, pyrin domain containing 9 -1.65138
PNPLA7 patatin-like phospholipase domain containing 7 -1.65125
PPCS phosphopantothenoylcysteine synthetase -1.64591
CGGBP1 CGG triplet repeat binding protein 1 -1.64331
CREB1 cAMP responsive element binding protein 1 -1.6349
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -1.63268
POLQ polymerase (DNA directed), theta -1.63231
NIPAL4 NIPA-like domain containing 4 -1.63031
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -1.62763
CSE1L CSE1 chromosome segregation 1-like (yeast) -1.6186
THRB thyroid hormone receptor, beta -1.61838
C2ORF76 chromosome 2 open reading frame 76 -1.61217
RS1 retinoschisin 1 -1.60952
LBR lamin B receptor -1.60562
RPL5 ribosomal protein L5 -1.60426
VANGL2 VANGL planar cell polarity protein 2 -1.60413
CCDC64 coiled-coil domain containing 64 -1.60163
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) -1.60161
ARHGAP35 Rho GTPase activating protein 35 -1.60121
EPC1 enhancer of polycomb homolog 1 (Drosophila) -1.59882
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -1.59826
CCPG1 cell cycle progression 1 -1.59808
MRPS22 mitochondrial ribosomal protein S22 -1.59637
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -1.59635
TNFAIP8L1 tumor necrosis factor, alpha-induced protein 8-like 1 -1.58998
DERA deoxyribose-phosphate aldolase (putative) -1.58646
ABRACL ABRA C-terminal like -1.58193
TUBA1A tubulin, alpha 1a -1.57999
FLI1 Fli-1 proto-oncogene, ETS transcription factor -1.57851
USP2 ubiquitin specific peptidase 2 -1.57656
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -1.5724
NOL11 nucleolar protein 11 -1.57214
CLVS2 clavesin 2 -1.57008
RPL27A ribosomal protein L27a -1.56712
TMEM60 transmembrane protein 60 -1.56608
BLZF1 basic leucine zipper nuclear factor 1 -1.56465
KLF2 Kruppel-like factor 2 -1.56439
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) -1.56438
SAMD9L sterile alpha motif domain containing 9-like -1.56363
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.56206
NAP1L5 nucleosome assembly protein 1-like 5 -1.55926
SMIM15 small integral membrane protein 15 -1.55845
EMC4 ER membrane protein complex subunit 4 -1.55446
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -1.55229
SDF2 stromal cell-derived factor 2 -1.54617
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -1.54354
DCSTAMP dendrocyte expressed seven transmembrane protein -1.54232
FAM207A family with sequence similarity 207, member A -1.54131
TJAP1 tight junction associated protein 1 (peripheral) -1.53859
PACS2 phosphofurin acidic cluster sorting protein 2 -1.53792
MCM3AP minichromosome maintenance complex component 3 associated protein -1.53741
MRC2 mannose receptor, C type 2 -1.53721
CREBRF CREB3 regulatory factor -1.53621
FAM198B family with sequence similarity 198, member B -1.52049
TUBGCP6 tubulin, gamma complex associated protein 6 -1.51629
LBP lipopolysaccharide binding protein -1.51219
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -1.51005
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -1.49642
MRPL43 mitochondrial ribosomal protein L43 -1.48839
FBLN7 fibulin 7 -1.48282
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 -1.48151
STAU1 staufen double-stranded RNA binding protein 1 -1.48118
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -1.4788
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -1.47621
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -1.46702
ZNF32 zinc finger protein 32 -1.46578
CCDC51 coiled-coil domain containing 51 -1.4628
BICD2 bicaudal D homolog 2 (Drosophila) -1.4609
LONRF3 LON peptidase N-terminal domain and ring finger 3 -1.46054
RPL21 ribosomal protein L21 -1.45996
KIAA0586 KIAA0586 -1.45971
TXLNA taxilin alpha -1.45374
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2 -1.45124
CD96 CD96 molecule -1.44604
FAM32A family with sequence similarity 32, member A -1.44357
KLHL18 kelch-like family member 18 -1.44299
APOOL apolipoprotein O-like -1.43933
NSUN4 NOP2/Sun domain family, member 4 -1.43847
KXD1 KxDL motif containing 1 -1.43603
PFDN2 prefoldin subunit 2 -1.43525
ADPRH ADP-ribosylarginine hydrolase -1.43146
CLEC4G C-type lectin domain family 4, member G -1.42863
MTNR1A melatonin receptor 1A -1.42538
ZZZ3 zinc finger, ZZ-type containing 3 -1.42365
PPP1R18 protein phosphatase 1, regulatory subunit 18 -1.42362
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -1.42124
CLHC1 clathrin heavy chain linker domain containing 1 -1.41714
KDM7A lysine (K)-specific demethylase 7A -1.4152
SOS1 son of sevenless homolog 1 (Drosophila) -1.4149
AKAP7 A kinase (PRKA) anchor protein 7 -1.41387
ENPEP glutamyl aminopeptidase (aminopeptidase A) -1.41215
TIMD4 T-cell immunoglobulin and mucin domain containing 4 -1.40989
STAG2 stromal antigen 2 -1.40944
ERO1LB ERO1-like beta (S. cerevisiae) -1.40572
CDC42SE1 CDC42 small effector 1 -1.40075
CAT catalase -1.39719
RGMB repulsive guidance molecule family member b -1.39329
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -1.39175
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -1.39109
EXOC8 exocyst complex component 8 -1.38381
TRABD2B TraB domain containing 2B -1.38348
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -1.38176
MUC15 mucin 15, cell surface associated -1.37907
KCMF1 potassium channel modulatory factor 1 -1.37877
AKIRIN1 akirin 1 -1.37739
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -1.37563
ZDHHC15 zinc finger, DHHC-type containing 15 -1.37231
UBE4B ubiquitination factor E4B -1.37163
RPS28 ribosomal protein S28 -1.37127
FMO5 flavin containing monooxygenase 5 -1.37011
SIL1 SIL1 nucleotide exchange factor -1.36698
EHMT1 euchromatic histone-lysine N-methyltransferase 1 -1.36659
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 -1.36487
HAS2 hyaluronan synthase 2 -1.3648
CARD6 caspase recruitment domain family, member 6 -1.36312
RPL15 ribosomal protein L15 -1.35724
SPINT1 serine peptidase inhibitor, Kunitz type 1 -1.35679
NONO non-POU domain containing, octamer-binding -1.35603
OXCT1 3-oxoacid CoA transferase 1 -1.35383
RPL7 ribosomal protein L7 -1.3528
STRN striatin, calmodulin binding protein -1.35263
TWF2 twinfilin actin binding protein 2 -1.35178
LRRC71 leucine rich repeat containing 71 -1.35048
LACTB2 lactamase, beta 2 -1.34953
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -1.34937
NAIF1 nuclear apoptosis inducing factor 1 -1.3485
LRRC26 leucine rich repeat containing 26 -1.34706
AMER1 APC membrane recruitment protein 1 -1.34614
MTMR6 myotubularin related protein 6 -1.34537
MPRIP myosin phosphatase Rho interacting protein -1.34417
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -1.34412
MYH11 myosin, heavy chain 11, smooth muscle -1.34297
GLI2 GLI family zinc finger 2 -1.34296
HMG20B high mobility group 20B -1.33986
SLC39A10 solute carrier family 39 (zinc transporter), member 10 -1.3386
ALS2CL ALS2 C-terminal like -1.33487
PCBP2 poly(rC) binding protein 2 -1.33353
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) -1.33258
C12ORF45 chromosome 12 open reading frame 45 -1.33047
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26 -1.32727
IFI16 interferon, gamma-inducible protein 16 -1.32342
DIEXF digestive organ expansion factor homolog (zebrafish) -1.31819
MESDC2 mesoderm development candidate 2 -1.31656
ABLIM1 actin binding LIM protein 1 -1.31428
S100A16 S100 calcium binding protein A16 -1.31252
TMX3 thioredoxin-related transmembrane protein 3 -1.30728
IST1 increased sodium tolerance 1 homolog (yeast) -1.30465
CACTIN cactin, spliceosome C complex subunit -1.30255
ICE1 interactor of little elongation complex ELL subunit 1 -1.3022
COL9A3 collagen, type IX, alpha 3 -1.29633
PRAMEF12 PRAME family member 12 -1.29611
C7ORF26 chromosome 7 open reading frame 26 -1.29442
TUBGCP5 tubulin, gamma complex associated protein 5 -1.29271
TOB2 transducer of ERBB2, 2 -1.29085
CNR1 cannabinoid receptor 1 (brain) -1.28999
C10ORF54 chromosome 10 open reading frame 54 -1.28858
BUD13 BUD13 homolog (S. cerevisiae) -1.28507
TTI2 TELO2 interacting protein 2 -1.28501
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) -1.28447
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -1.28422
SPTAN1 spectrin, alpha, non-erythrocytic 1 -1.28276
WDR54 WD repeat domain 54 -1.28004
SCN7A sodium channel, voltage gated, type VII alpha subunit -1.2799
IQCC IQ motif containing C -1.27678
ANAPC16 anaphase promoting complex subunit 16 -1.27559
ZBTB43 zinc finger and BTB domain containing 43 -1.27243
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -1.27242
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 -1.27133
C12ORF4 chromosome 12 open reading frame 4 -1.27049
CDC37L1 cell division cycle 37-like 1 -1.27049
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -1.26762
UFM1 ubiquitin-fold modifier 1 -1.26641
LIMK2 LIM domain kinase 2 -1.26462
GMCL1 germ cell-less, spermatogenesis associated 1 -1.26312
CD2AP CD2-associated protein -1.2631
NSDHL NAD(P) dependent steroid dehydrogenase-like -1.26285
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -1.26254
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -1.26093
BCAS3 breast carcinoma amplified sequence 3 -1.26084
PRMT9 protein arginine methyltransferase 9 -1.26014
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa -1.25997
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -1.25733
GPR132 G protein-coupled receptor 132 -1.25469
MCOLN3 mucolipin 3 -1.25449
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -1.25432
PXK PX domain containing serine/threonine kinase -1.25348
NLRP3 NLR family, pyrin domain containing 3 -1.24909
CORO1A coronin, actin binding protein, 1A -1.24855