| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/60753 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Ibutilide relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATXN7L3 | ataxin 7-like 3 | 1.23 |
| PRKD2 | protein kinase D2 | 0.77 |
| ZNF799 | zinc finger protein 799 | 0.66 |
| ZW10 | zw10 kinetochore protein | 0.57 |
| BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | 0.56 |
| ABHD15 | abhydrolase domain containing 15 | 0.52 |
| SMTN | smoothelin | 0.49 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.48 |
| TTC9C | tetratricopeptide repeat domain 9C | 0.48 |
| SH3BGRL2 | SH3 domain binding glutamate-rich protein like 2 | 0.46 |
| TMEM175 | transmembrane protein 175 | 0.46 |
| CLK4 | CDC-like kinase 4 | 0.45 |
| UBE3B | ubiquitin protein ligase E3B | 0.44 |
| PML | promyelocytic leukemia | 0.43 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.43 |
| ZNRD1 | zinc ribbon domain containing 1 | 0.42 |
| SLC30A6 | solute carrier family 30 (zinc transporter), member 6 | 0.41 |
| FOXP1 | forkhead box P1 | 0.41 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.41 |
| YIPF6 | Yip1 domain family, member 6 | 0.41 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.41 |
| DMD | dystrophin | 0.4 |
| FRY | furry homolog (Drosophila) | 0.4 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.4 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.39 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.39 |
| ZNF516 | zinc finger protein 516 | 0.39 |
| IL10RB | interleukin 10 receptor, beta | 0.39 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.38 |
| SNX21 | sorting nexin family member 21 | 0.37 |
| GAB1 | GRB2-associated binding protein 1 | 0.37 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.35 |
| TSLIG1 | tRNA splicing ligase complex subunit 1 | 0.35 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.35 |
| PRKCQ | protein kinase C, theta | 0.35 |
| USP46 | ubiquitin specific peptidase 46 | 0.34 |
| IFT43 | intraflagellar transport 43 | 0.34 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.34 |
| RPL37 | ribosomal protein L37 | 0.34 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.33 |
| TNS1 | tensin 1 | 0.33 |
| GRAMD1A | GRAM domain containing 1A | 0.33 |
| CEP85 | centrosomal protein 85kDa | 0.33 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.33 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.33 |
| SNX1 | sorting nexin 1 | 0.32 |
| MFSD8 | major facilitator superfamily domain containing 8 | 0.32 |
| BCL7C | B-cell CLL/lymphoma 7C | 0.32 |
| SNPH | syntaphilin | 0.32 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.32 |
| RSF1 | remodeling and spacing factor 1 | 0.32 |
| WDR5B | WD repeat domain 5B | 0.32 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein | 0.31 |
| TPM1 | tropomyosin 1 (alpha) | 0.31 |
| RGS12 | regulator of G-protein signaling 12 | 0.31 |
| ABCB10 | ATP-binding cassette, sub-family B (MDR/TAP), member 10 | 0.31 |
| COPRS | coordinator of PRMT5, differentiation stimulator | 0.3 |
| ZNF8 | zinc finger protein 8 | 0.3 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.3 |
| YAE1 | YAE1 maturation factor of ABCE1 | 0.3 |
| SLC35F3 | solute carrier family 35, member F3 | 0.29 |
| C2ORF42 | chromosome 2 open reading frame 42 | 0.29 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.29 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.29 |
| DOCK5 | dedicator of cytokinesis 5 | 0.29 |
| FBXO46 | F-box protein 46 | 0.29 |
| TMPO | thymopoietin | 0.29 |
| SELENBP1 | selenium binding protein 1 | 0.29 |
| RNF149 | ring finger protein 149 | 0.29 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.29 |
| ATE1 | arginyltransferase 1 | 0.28 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.28 |
| ANXA2 | annexin A2 | 0.28 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.28 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.28 |
| KLHL15 | kelch-like family member 15 | 0.28 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.28 |
| SUMO2 | small ubiquitin-like modifier 2 | 0.27 |
| C1ORF226 | chromosome 1 open reading frame 226 | 0.27 |
| DIRAS1 | DIRAS family, GTP-binding RAS-like 1 | 0.27 |
| CTPS1 | CTP synthase 1 | 0.26 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.26 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.26 |
| FTL | ferritin, light polypeptide | 0.26 |
| DENND4B | DENN/MADD domain containing 4B | 0.26 |
| ZNF483 | zinc finger protein 483 | 0.26 |
| ZNF611 | zinc finger protein 611 | 0.26 |
| RGPD8 | RANBP2-like and GRIP domain containing 8 | 0.26 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.26 |
| SIK2 | salt-inducible kinase 2 | 0.26 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.26 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.26 |
| BBS2 | Bardet-Biedl syndrome 2 | 0.26 |
| STARD3NL | STARD3 N-terminal like | 0.25 |
| RAD54L | RAD54-like (S. cerevisiae) | 0.25 |
| MED10 | mediator complex subunit 10 | 0.25 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.25 |
| PDP2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | 0.25 |
| CEP44 | centrosomal protein 44kDa | 0.25 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.24 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.81 |
| CALD1 | caldesmon 1 | -0.67 |
| SQSTM1 | sequestosome 1 | -0.66 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 | -0.65 |
| INO80D | INO80 complex subunit D | -0.62 |
| ZC3H14 | zinc finger CCCH-type containing 14 | -0.59 |
| RGN | regucalcin | -0.58 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.57 |
| FLYWCH1 | FLYWCH-type zinc finger 1 | -0.57 |
| VASN | vasorin | -0.55 |
| LTA4H | leukotriene A4 hydrolase | -0.54 |
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | -0.53 |
| TUBA1C | tubulin, alpha 1c | -0.51 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.49 |
| PLCD1 | phospholipase C, delta 1 | -0.49 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.48 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.47 |
| TMEM173 | transmembrane protein 173 | -0.47 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) | -0.46 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | -0.46 |
| IFRD1 | interferon-related developmental regulator 1 | -0.43 |
| C15ORF61 | chromosome 15 open reading frame 61 | -0.42 |
| ZNF12 | zinc finger protein 12 | -0.41 |
| HDAC1 | histone deacetylase 1 | -0.41 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.41 |
| ABRAXAS1 | abraxas 1, BRCA1 A complex subunit | -0.4 |
| ABHD2 | abhydrolase domain containing 2 | -0.4 |
| CA8 | carbonic anhydrase VIII | -0.4 |
| CLIC3 | chloride intracellular channel 3 | -0.4 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | -0.4 |
| PDE5A | phosphodiesterase 5A, cGMP-specific | -0.4 |
| RNF13 | ring finger protein 13 | -0.39 |
| SLC25A44 | solute carrier family 25, member 44 | -0.39 |
| BCORL1 | BCL6 corepressor-like 1 | -0.39 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | -0.38 |
| AUNIP | aurora kinase A and ninein interacting protein | -0.38 |
| DTX2 | deltex 2, E3 ubiquitin ligase | -0.38 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.38 |
| NSUN3 | NOP2/Sun domain family, member 3 | -0.38 |
| MTMR8 | myotubularin related protein 8 | -0.37 |
| PYCR3 | pyrroline-5-carboxylate reductase 3 | -0.37 |
| HLA-B | major histocompatibility complex, class I, B | -0.37 |
| UXS1 | UDP-glucuronate decarboxylase 1 | -0.37 |
| UBXN8 | UBX domain protein 8 | -0.36 |
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 | -0.36 |
| EFCAB14 | EF-hand calcium binding domain 14 | -0.35 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | -0.35 |
| FAM160A1 | family with sequence similarity 160, member A1 | -0.35 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.34 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.34 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | -0.34 |
| H2AFX | H2A histone family, member X | -0.34 |
| DXO | decapping exoribonuclease | -0.34 |
| ATP9B | ATPase, class II, type 9B | -0.33 |
| RPS29 | ribosomal protein S29 | -0.32 |
| C12ORF4 | chromosome 12 open reading frame 4 | -0.32 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.32 |
| DPY30 | dpy-30 homolog (C. elegans) | -0.32 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | -0.32 |
| WHAMM | WAS protein homolog associated with actin, golgi membranes and microtubules | -0.32 |
| COA3 | cytochrome c oxidase assembly factor 3 | -0.31 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.31 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.31 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.31 |
| GAS8 | growth arrest-specific 8 | -0.31 |
| USP40 | ubiquitin specific peptidase 40 | -0.31 |
| ORMDL1 | ORMDL sphingolipid biosynthesis regulator 1 | -0.31 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) | -0.3 |
| DEPDC7 | DEP domain containing 7 | -0.3 |
| MRFAP1 | Morf4 family associated protein 1 | -0.3 |
| RNASEH2C | ribonuclease H2, subunit C | -0.3 |
| NPHP4 | nephronophthisis 4 | -0.3 |
| MYH7B | myosin, heavy chain 7B, cardiac muscle, beta | -0.3 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) | -0.3 |
| BORA | bora, aurora kinase A activator | -0.29 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.29 |
| SAMD8 | sterile alpha motif domain containing 8 | -0.29 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.29 |
| LIPA | lipase A, lysosomal acid, cholesterol esterase | -0.29 |
| NES | nestin | -0.28 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | -0.28 |
| CDC25B | cell division cycle 25B | -0.28 |
| SH2D5 | SH2 domain containing 5 | -0.28 |
| ELMO2 | engulfment and cell motility 2 | -0.28 |
| BRCA1 | breast cancer 1, early onset | -0.27 |
| PLAU | plasminogen activator, urokinase | -0.27 |
| LZTR1 | leucine-zipper-like transcription regulator 1 | -0.27 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.27 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 | -0.27 |
| OGG1 | 8-oxoguanine DNA glycosylase | -0.27 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.26 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.26 |
| PAXX | PAXX non-homologous end joining factor | -0.26 |
| CPNE7 | copine VII | -0.26 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.26 |
| MED19 | mediator complex subunit 19 | -0.26 |
| TAPBP | TAP binding protein (tapasin) | -0.26 |
| CEP63 | centrosomal protein 63kDa | -0.25 |
| BAG1 | BCL2-associated athanogene | -0.25 |
