| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0797142 |
| PLAT | plasminogen activator, tissue | 0.0760798 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0749108 |
| PODXL | podocalyxin-like | 0.0659982 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0431069 |
| MYADM | myeloid-associated differentiation marker | 0.042426 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0412345 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0391216 |
| BCL2L1 | BCL2-like 1 | 0.0358628 |
| SEPTIN9 | septin 9 | 0.03289 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0279453 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0271804 |
| EGR1 | early growth response 1 | 0.0266507 |
| GOLGA4 | golgin A4 | 0.0261461 |
| RND3 | Rho family GTPase 3 | 0.025792 |
| EZR | ezrin | 0.0256279 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0251159 |
| AXL | AXL receptor tyrosine kinase | 0.0244371 |
| HDAC9 | histone deacetylase 9 | 0.0239355 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0228562 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0211217 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0208296 |
| RTN4 | reticulon 4 | 0.0202121 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0201545 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.0196638 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0196059 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.01904 |
| FLNB | filamin B, beta | 0.0186322 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0184407 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.018409 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0182479 |
| PTCHD4 | patched domain containing 4 | 0.0179918 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.0179385 |
| FAM107B | family with sequence similarity 107, member B | 0.0178207 |
| EGFR | epidermal growth factor receptor | 0.0176984 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0172313 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0171733 |
| GDF15 | growth differentiation factor 15 | 0.0169012 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0168275 |
| RPS2 | ribosomal protein S2 | 0.0159809 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 0.0153388 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0152781 |
| RPS6 | ribosomal protein S6 | 0.0149221 |
| FOSL2 | FOS-like antigen 2 | 0.0147259 |
| DEPP1 | DEPP autophagy regulator 1 | 0.014151 |
| TPM3 | tropomyosin 3 | 0.0140126 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0138096 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0137424 |
| ANKRD30B | ankyrin repeat domain 30B | 0.013725 |
| L1CAM | L1 cell adhesion molecule | 0.0135414 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.013519 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0134242 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0132564 |
| FAT1 | FAT atypical cadherin 1 | 0.0127464 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0125238 |
| FOSL1 | FOS-like antigen 1 | 0.0124914 |
| PLXNA2 | plexin A2 | 0.0124301 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.012409 |
| KRT81 | keratin 81, type II | 0.0121817 |
| RARA | retinoic acid receptor, alpha | 0.0120978 |
| DSPP | dentin sialophosphoprotein | 0.0114935 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0113624 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0113526 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0112304 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0112126 |
| C1D | C1D nuclear receptor corepressor | 0.0111929 |
| MINK1 | misshapen-like kinase 1 | 0.0110926 |
| TBC1D2 | TBC1 domain family, member 2 | 0.0110565 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0110489 |
| FHL2 | four and a half LIM domains 2 | 0.01097 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0106875 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0106611 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0105979 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.0105432 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0105384 |
| KIF1C | kinesin family member 1C | 0.0104882 |
| PLK2 | polo-like kinase 2 | 0.0104107 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.010102 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0100788 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00999288 |
| ZFP36 | ZFP36 ring finger protein | 0.00998965 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0099134 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00982695 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00979971 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.00977592 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.00969724 |
| WDR43 | WD repeat domain 43 | 0.00966625 |
| RPS27L | ribosomal protein S27-like | 0.00966023 |
| MSN | moesin | 0.00962756 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.00955607 |
| SERTAD2 | SERTA domain containing 2 | 0.00954056 |
| XPC | xeroderma pigmentosum, complementation group C | 0.009473 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00943377 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0093388 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00929909 |
| CD68 | CD68 molecule | 0.00928593 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00923286 |
| ACER3 | alkaline ceramidase 3 | 0.00920274 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00907362 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.00904216 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.223774 |
| TMSB10 | thymosin beta 10 | -0.219791 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.133573 |
| FBN1 | fibrillin 1 | -0.124614 |
| AHNAK | AHNAK nucleoprotein | -0.114777 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.114345 |
| LOX | lysyl oxidase | -0.106035 |
| VIM | vimentin | -0.096739 |
| COL5A2 | collagen, type V, alpha 2 | -0.0964459 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0940594 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0820764 |
| RIGI | RNA sensor RIG-I | -0.0814894 |
| LDHA | lactate dehydrogenase A | -0.0756427 |
| COL3A1 | collagen, type III, alpha 1 | -0.0737893 |
| CANX | calnexin | -0.0731814 |
| COL1A2 | collagen, type I, alpha 2 | -0.0727862 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0713471 |
| FN1 | fibronectin 1 | -0.0697491 |
| ANXA2 | annexin A2 | -0.0690803 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0663578 |
| SQSTM1 | sequestosome 1 | -0.0662988 |
| AUTS2 | autism susceptibility candidate 2 | -0.0661643 |
| HLA-B | major histocompatibility complex, class I, B | -0.0661428 |
| MT2A | metallothionein 2A | -0.0647967 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0624298 |
| S100A10 | S100 calcium binding protein A10 | -0.0621021 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0618804 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.061739 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0609537 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0603383 |
| B2M | beta-2-microglobulin | -0.0598033 |
| PTMA | prothymosin, alpha | -0.0586436 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.058603 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0579831 |
| PRELID2 | PRELI domain containing 2 | -0.0575961 |
| NAV1 | neuron navigator 1 | -0.056459 |
| LOXL2 | lysyl oxidase-like 2 | -0.0561854 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0559787 |
| DST | dystonin | -0.0558821 |
| LMNA | lamin A/C | -0.0552048 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0551035 |
| PGK1 | phosphoglycerate kinase 1 | -0.0542762 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0540155 |
| UBC | ubiquitin C | -0.0536283 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0531501 |
| TAGLN2 | transgelin 2 | -0.0527661 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0527136 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0519574 |
| COL5A1 | collagen, type V, alpha 1 | -0.0510527 |
| GPC6 | glypican 6 | -0.0504054 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0502687 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0498962 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0494343 |
| GLIS3 | GLIS family zinc finger 3 | -0.0494252 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0487826 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0484995 |
| THBS2 | thrombospondin 2 | -0.0469107 |
| MX2 | MX dynamin-like GTPase 2 | -0.046157 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0458243 |
| MEIS2 | Meis homeobox 2 | -0.045536 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0452854 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0450839 |
| TMSB4X | thymosin beta 4, X-linked | -0.0450205 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0445191 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0440671 |
| FSTL1 | follistatin-like 1 | -0.0436614 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0436518 |
| HLA-C | major histocompatibility complex, class I, C | -0.0435656 |
| MAP4 | microtubule-associated protein 4 | -0.0429743 |
| RNF213 | ring finger protein 213 | -0.0429512 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0423703 |
| VCL | vinculin | -0.0419568 |
| APP | amyloid beta (A4) precursor protein | -0.0418525 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0417149 |
| MAP1B | microtubule-associated protein 1B | -0.0415831 |
| PRSS23 | protease, serine, 23 | -0.0413658 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0413008 |
| PKM | pyruvate kinase, muscle | -0.041292 |
| MYOF | myoferlin | -0.0411476 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0408644 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0395142 |
| ACTN4 | actinin, alpha 4 | -0.0388865 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0387999 |
| CAVIN1 | caveolae associated protein 1 | -0.038724 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0382382 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0379347 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0372422 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0369403 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0367301 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0365932 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0359451 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0356924 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0349737 |
| CDH13 | cadherin 13 | -0.0348546 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.034839 |
| TPM4 | tropomyosin 4 | -0.034809 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0345027 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.033855 |
| GNAS | GNAS complex locus | -0.0336044 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0335809 |
