| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0892908 |
| RPS6 | ribosomal protein S6 | 0.0889903 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0639052 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0580609 |
| RPS2 | ribosomal protein S2 | 0.0540944 |
| TPM3 | tropomyosin 3 | 0.0391022 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0375029 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0344389 |
| GPC5 | glypican 5 | 0.0319857 |
| SFTPA2 | surfactant protein A2 | 0.0310844 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0296151 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0294907 |
| TLN1 | talin 1 | 0.0279306 |
| FTL | ferritin, light polypeptide | 0.0275379 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0268932 |
| CTSD | cathepsin D | 0.0249495 |
| RPS8 | ribosomal protein S8 | 0.0244247 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0240397 |
| RND3 | Rho family GTPase 3 | 0.0223285 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0217632 |
| ATF3 | activating transcription factor 3 | 0.0212149 |
| DSTN | destrin (actin depolymerizing factor) | 0.0202473 |
| CALR | calreticulin | 0.0199701 |
| RPL4 | ribosomal protein L4 | 0.0198587 |
| IL32 | interleukin 32 | 0.0196541 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0195117 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0192677 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0187713 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0183598 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0179736 |
| SERF2 | small EDRK-rich factor 2 | 0.0178654 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0174267 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0171686 |
| YBX1 | Y box binding protein 1 | 0.0170332 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0168843 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0167036 |
| SEPTIN9 | septin 9 | 0.0166251 |
| FLNA | filamin A, alpha | 0.0165192 |
| MSN | moesin | 0.0164996 |
| RPLP2 | ribosomal protein, large, P2 | 0.0158178 |
| TPI1 | triosephosphate isomerase 1 | 0.0158114 |
| TAFA2 | TAFA chemokine like family member 2 | 0.0154506 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0153156 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0152103 |
| RPS12 | ribosomal protein S12 | 0.0149856 |
| S100A11 | S100 calcium binding protein A11 | 0.0149225 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0149036 |
| BRD2 | bromodomain containing 2 | 0.014431 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0143557 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0142732 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0141416 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.013874 |
| GRN | granulin | 0.013769 |
| RIPOR1 | RHO family interacting cell polarization regulator 1 | 0.0137679 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0136766 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0135722 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0135366 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0134526 |
| TUBA1B | tubulin, alpha 1b | 0.0133969 |
| RTN4 | reticulon 4 | 0.013331 |
| OPTN | optineurin | 0.0130465 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0129931 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0123999 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0123014 |
| EPHA4 | EPH receptor A4 | 0.0121992 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0121782 |
| HMGB2 | high mobility group box 2 | 0.0121725 |
| RPL26 | ribosomal protein L26 | 0.0121066 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0121041 |
| ACYP2 | acylphosphatase 2, muscle type | 0.0119595 |
| KIF5B | kinesin family member 5B | 0.0118496 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0118075 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.0117948 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0117881 |
| E2F7 | E2F transcription factor 7 | 0.0117463 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0117455 |
| RPL14 | ribosomal protein L14 | 0.0116409 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.0115831 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.011567 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0115343 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0115185 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0115059 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0114655 |
| KLHL29 | kelch-like family member 29 | 0.0113927 |
| FAM219A | family with sequence similarity 219, member A | 0.0113809 |
| CXXC1 | CXXC finger protein 1 | 0.0112725 |
| GNAS | GNAS complex locus | 0.0111648 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.0110798 |
| RPL12 | ribosomal protein L12 | 0.0110399 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0109383 |
| C8ORF33 | chromosome 8 open reading frame 33 | 0.010896 |
| SELENOK | selenoprotein K | 0.0108705 |
| CD99 | CD99 molecule | 0.0108218 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0107052 |
| RPL13A | ribosomal protein L13a | 0.0107021 |
| STOM | stomatin | 0.0106972 |
| RPS3 | ribosomal protein S3 | 0.0106528 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0106185 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0105675 |
| SYAP1 | synapse associated protein 1 | 0.0105398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | -0.265711 |
| EXT1 | exostosin glycosyltransferase 1 | -0.122165 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.114999 |
| FRMD4A | FERM domain containing 4A | -0.101153 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0924158 |
| RAI14 | retinoic acid induced 14 | -0.0918365 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0858675 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0830225 |
| GLIS3 | GLIS family zinc finger 3 | -0.0820748 |
| NDRG1 | N-myc downstream regulated 1 | -0.080642 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0742609 |
| VIM | vimentin | -0.0718229 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0708876 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0704518 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0619979 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0590584 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0581191 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0553793 |
| CD44 | CD44 molecule (Indian blood group) | -0.0535453 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0523912 |
| CP | ceruloplasmin (ferroxidase) | -0.0522752 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0513559 |
| ASPH | aspartate beta-hydroxylase | -0.0506966 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0504958 |
| TXNRD1 | thioredoxin reductase 1 | -0.0503257 |
| VCL | vinculin | -0.0497679 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0488084 |
| PLIN2 | perilipin 2 | -0.0480563 |
| SMAD3 | SMAD family member 3 | -0.0475633 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0456725 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0452555 |
| SPAG9 | sperm associated antigen 9 | -0.0445497 |
| KYNU | kynureninase | -0.0444319 |
| MAP1B | microtubule-associated protein 1B | -0.0443467 |
| NRP2 | neuropilin 2 | -0.0440156 |
| PALLD | palladin, cytoskeletal associated protein | -0.0428866 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0419892 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0419 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0417239 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0406592 |
| COPA | coatomer protein complex, subunit alpha | -0.0401688 |
| COG5 | component of oligomeric golgi complex 5 | -0.0399974 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0398082 |
| RHEB | Ras homolog enriched in brain | -0.0396752 |
| CALU | calumenin | -0.0387059 |
| CA12 | carbonic anhydrase XII | -0.0385984 |
| MX1 | MX dynamin-like GTPase 1 | -0.0385203 |
| TPM1 | tropomyosin 1 (alpha) | -0.0383305 |
| TMSB10 | thymosin beta 10 | -0.03717 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0369333 |
| DIAPH3 | diaphanous-related formin 3 | -0.0368874 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0366839 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0361753 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0358393 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0350181 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0348667 |
| RNF213 | ring finger protein 213 | -0.0347397 |
| PAX8 | paired box 8 | -0.0344743 |
| RRBP1 | ribosome binding protein 1 | -0.0344592 |
| MORF4L2 | mortality factor 4 like 2 | -0.034026 |
| IRS2 | insulin receptor substrate 2 | -0.0338982 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0336188 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0335268 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0332748 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0328895 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0326247 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0323581 |
| CLINT1 | clathrin interactor 1 | -0.0318734 |
| RRM2 | ribonucleotide reductase M2 | -0.0317753 |
| STK17A | serine/threonine kinase 17a | -0.0316694 |
| NFIB | nuclear factor I/B | -0.031593 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.031538 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0314278 |
| NF1 | neurofibromin 1 | -0.0313617 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0313163 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0311193 |
| TNS3 | tensin 3 | -0.0310567 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.030849 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0306927 |
| POTEF | POTE ankyrin domain family, member F | -0.0302505 |
| PTK2 | protein tyrosine kinase 2 | -0.0302075 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0300272 |
| LDHA | lactate dehydrogenase A | -0.0292111 |
| SBF2 | SET binding factor 2 | -0.0291002 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0290635 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0288791 |
| RAD51B | RAD51 paralog B | -0.0286368 |
| FMNL2 | formin-like 2 | -0.0284873 |
| NRP1 | neuropilin 1 | -0.0284863 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0284707 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0284081 |
| ITGAV | integrin, alpha V | -0.0282802 |
| SQSTM1 | sequestosome 1 | -0.0282148 |
| RPL35A | ribosomal protein L35a | -0.0280719 |
| MTDH | metadherin | -0.0278662 |
| CBX3 | chromobox homolog 3 | -0.0277098 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0275758 |
| LMAN1 | lectin, mannose-binding, 1 | -0.027437 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0274182 |
| UBC | ubiquitin C | -0.0274065 |
