| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS2 | ribosomal protein S2 | 0.0936493 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.081848 |
| HIP1 | huntingtin interacting protein 1 | 0.0661199 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0585828 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0538655 |
| BCOR | BCL6 corepressor | 0.0531221 |
| GSE1 | Gse1 coiled-coil protein | 0.0524635 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0441499 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0435661 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0422318 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0411187 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0410945 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0401345 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0390027 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0386528 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.036147 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0347104 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0340533 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | 0.0333344 |
| RAD51B | RAD51 paralog B | 0.0329729 |
| HDGFL3 | HDGF like 3 | 0.0315312 |
| ERBIN | erbb2 interacting protein | 0.0308432 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0308141 |
| SFTPA2 | surfactant protein A2 | 0.0305797 |
| RRM2 | ribonucleotide reductase M2 | 0.0304554 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0303735 |
| NTN1 | netrin 1 | 0.0297272 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0295447 |
| TCF12 | transcription factor 12 | 0.0294882 |
| IRF3 | interferon regulatory factor 3 | 0.0294249 |
| HOXA3 | homeobox A3 | 0.0291656 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0287474 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0283727 |
| RPL4 | ribosomal protein L4 | 0.02837 |
| KLHL29 | kelch-like family member 29 | 0.0278398 |
| FUS | FUS RNA binding protein | 0.0269522 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.0267914 |
| GNAS | GNAS complex locus | 0.0267359 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0260955 |
| TPM3 | tropomyosin 3 | 0.025875 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0258607 |
| CUX1 | cut-like homeobox 1 | 0.0258328 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0254807 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0254668 |
| YBX3 | Y box binding protein 3 | 0.0253192 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0241887 |
| KIF26B | kinesin family member 26B | 0.0241887 |
| REST | RE1-silencing transcription factor | 0.024106 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0240495 |
| PHF21B | PHD finger protein 21B | 0.0240357 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | 0.0237901 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0237679 |
| RPS6 | ribosomal protein S6 | 0.0235207 |
| NIN | ninein (GSK3B interacting protein) | 0.0234892 |
| POM121 | POM121 transmembrane nucleoporin | 0.0233875 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | 0.023291 |
| SYAP1 | synapse associated protein 1 | 0.0231123 |
| FNBP1 | formin binding protein 1 | 0.0229922 |
| CLSPN | claspin | 0.0229746 |
| NRG2 | neuregulin 2 | 0.0228776 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0228631 |
| UTRN | utrophin | 0.0227542 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0225919 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0225408 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0224642 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0224628 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0224566 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0223519 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | 0.0220894 |
| TOP1 | topoisomerase (DNA) I | 0.0220502 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0219823 |
| YBX1 | Y box binding protein 1 | 0.0218886 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0218583 |
| RPLP1 | ribosomal protein, large, P1 | 0.0218105 |
| PHF21A | PHD finger protein 21A | 0.0218003 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0217642 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 0.0217281 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0216433 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.0216309 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0214961 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0213407 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0212405 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0212019 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0211814 |
| CYTH3 | cytohesin 3 | 0.0211228 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0211029 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0210807 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0209966 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.0209754 |
| PITPNA | phosphatidylinositol transfer protein, alpha | 0.0208907 |
| BBX | bobby sox homolog (Drosophila) | 0.0207283 |
| CYTH1 | cytohesin 1 | 0.020665 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0206164 |
| MTREX | Mtr4 exosome RNA helicase | 0.0206065 |
| ZNF345 | zinc finger protein 345 | 0.0205729 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0205579 |
| CALR | calreticulin | 0.0205557 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0204976 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0201582 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0200976 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | -0.211091 |
| MEST | mesoderm specific transcript | -0.209609 |
| VIM | vimentin | -0.185109 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.135987 |
| PTMA | prothymosin, alpha | -0.0952233 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0869399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0860002 |
| NFIB | nuclear factor I/B | -0.0852798 |
| LDHA | lactate dehydrogenase A | -0.0801535 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0794953 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0786627 |
| PEG10 | paternally expressed 10 | -0.0742526 |
| NDRG1 | N-myc downstream regulated 1 | -0.0660391 |
| MEOX2 | mesenchyme homeobox 2 | -0.064968 |
| ENO1 | enolase 1, (alpha) | -0.0639188 |
| CENPF | centromere protein F, 350/400kDa | -0.0637997 |
| RPL35A | ribosomal protein L35a | -0.0629857 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0593865 |
| MT2A | metallothionein 2A | -0.0583808 |
| FNDC3B | fibronectin type III domain containing 3B | -0.049849 |
| RPS8 | ribosomal protein S8 | -0.0490912 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0489043 |
| HMGA2 | high mobility group AT-hook 2 | -0.047891 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0468564 |
| RPL34 | ribosomal protein L34 | -0.0452252 |
| MYOF | myoferlin | -0.0448326 |
| POTEF | POTE ankyrin domain family, member F | -0.0446162 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0437487 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0436463 |
| RPS25 | ribosomal protein S25 | -0.0431128 |
| ACTG1 | actin gamma 1 | -0.0420601 |
| FTL | ferritin, light polypeptide | -0.0399317 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0390896 |
| TMSB10 | thymosin beta 10 | -0.0384417 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0368827 |
| RPS5 | ribosomal protein S5 | -0.0367973 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0366025 |
| PKM | pyruvate kinase, muscle | -0.0360391 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0354727 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0348502 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0346953 |
| RPS13 | ribosomal protein S13 | -0.0344707 |
| MTDH | metadherin | -0.0339475 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0338924 |
| DEK | DEK proto-oncogene | -0.0337383 |
| TPM4 | tropomyosin 4 | -0.0331464 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0330401 |
| HMGA1 | high mobility group AT-hook 1 | -0.0329581 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0325667 |
| PGK1 | phosphoglycerate kinase 1 | -0.0323219 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0321486 |
| RPS23 | ribosomal protein S23 | -0.0320363 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0310437 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0303601 |
| CDK6 | cyclin-dependent kinase 6 | -0.0300535 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0298578 |
| ASPH | aspartate beta-hydroxylase | -0.0293244 |
| EGFR | epidermal growth factor receptor | -0.0282907 |
| CENPE | centromere protein E, 312kDa | -0.0282055 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0279036 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0277591 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0277455 |
| NF1 | neurofibromin 1 | -0.0275277 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0275045 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.027388 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0273699 |
| RPS19 | ribosomal protein S19 | -0.0273519 |
| SNX14 | sorting nexin 14 | -0.0269766 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0268283 |
| S100A9 | S100 calcium binding protein A9 | -0.0268093 |
| COPA | coatomer protein complex, subunit alpha | -0.0267431 |
| FLNB | filamin B, beta | -0.0266756 |
| UBE3C | ubiquitin protein ligase E3C | -0.0265186 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0262264 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0261113 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0261068 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0259659 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0256728 |
| SCFD1 | sec1 family domain containing 1 | -0.0256515 |
| SPPL3 | signal peptide peptidase like 3 | -0.0255788 |
| PRELID2 | PRELI domain containing 2 | -0.0253169 |
| ECT2 | epithelial cell transforming 2 | -0.0253053 |
| RPL23 | ribosomal protein L23 | -0.0252332 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0251454 |
| SEPTIN11 | septin 11 | -0.0249042 |
| RPL7A | ribosomal protein L7a | -0.0246856 |
| RPL9 | ribosomal protein L9 | -0.0245145 |
| INTS6 | integrator complex subunit 6 | -0.0243699 |
| COL5A2 | collagen, type V, alpha 2 | -0.0241211 |
| FN1 | fibronectin 1 | -0.024036 |
| RPS24 | ribosomal protein S24 | -0.0238617 |
| KAZN | kazrin, periplakin interacting protein | -0.0238371 |
| TUBB | tubulin, beta class I | -0.0236958 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0234282 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0233795 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0233398 |
| PCM1 | pericentriolar material 1 | -0.0232569 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0231715 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0231548 |
| FAM13A | family with sequence similarity 13, member A | -0.0231282 |
