| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.129787 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.109506 |
| SMAD3 | SMAD family member 3 | 0.0741146 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0673788 |
| RTN4 | reticulon 4 | 0.066745 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0649268 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0639097 |
| EGFR | epidermal growth factor receptor | 0.0627803 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0611796 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0610456 |
| EZR | ezrin | 0.0596736 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0570717 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0562321 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0556445 |
| RPS2 | ribosomal protein S2 | 0.0547678 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0518943 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0487289 |
| BCL2L1 | BCL2-like 1 | 0.0471015 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0467452 |
| DSPP | dentin sialophosphoprotein | 0.0463265 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0445418 |
| SGMS2 | sphingomyelin synthase 2 | 0.0444167 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0430071 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0421421 |
| TGM2 | transglutaminase 2 | 0.0420613 |
| RUNX1 | runt-related transcription factor 1 | 0.0408598 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0395023 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0394091 |
| SEPTIN9 | septin 9 | 0.0384894 |
| EFNA5 | ephrin-A5 | 0.0383036 |
| H1-0 | H1.0 linker histone | 0.0374084 |
| IL6ST | interleukin 6 signal transducer | 0.0367401 |
| CAB39 | calcium binding protein 39 | 0.0366526 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0365955 |
| RPS12 | ribosomal protein S12 | 0.0363561 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0350053 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0345076 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0338464 |
| RPS6 | ribosomal protein S6 | 0.0336952 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0336534 |
| WWC1 | WW and C2 domain containing 1 | 0.0334842 |
| CD44 | CD44 molecule (Indian blood group) | 0.0334204 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0330915 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0327893 |
| EHBP1 | EH domain binding protein 1 | 0.0326618 |
| TPI1 | triosephosphate isomerase 1 | 0.0310503 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0310202 |
| GDA | guanine deaminase | 0.0301167 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0300089 |
| TPM3 | tropomyosin 3 | 0.0292093 |
| BRD4 | bromodomain containing 4 | 0.0291385 |
| AHR | aryl hydrocarbon receptor | 0.0290443 |
| DUSP4 | dual specificity phosphatase 4 | 0.0290355 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0286377 |
| BRD2 | bromodomain containing 2 | 0.0281143 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0280321 |
| TLN1 | talin 1 | 0.0278308 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0277475 |
| RBBP6 | retinoblastoma binding protein 6 | 0.027356 |
| CREBBP | CREB binding protein | 0.0273003 |
| EGR1 | early growth response 1 | 0.0264743 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0263351 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0263006 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0262476 |
| MSN | moesin | 0.0255696 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0254224 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0254119 |
| CORO1C | coronin, actin binding protein, 1C | 0.0249889 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.024982 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.024971 |
| PCBP2 | poly(rC) binding protein 2 | 0.0247097 |
| VMP1 | vacuole membrane protein 1 | 0.0246324 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.02431 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.024246 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0241451 |
| MED13L | mediator complex subunit 13-like | 0.0241423 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0241403 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0238367 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0237821 |
| RIOK3 | RIO kinase 3 | 0.0236145 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.023281 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0231584 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0228138 |
| PAPOLA | poly(A) polymerase alpha | 0.022768 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0222559 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0222448 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0220837 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0214794 |
| CAPRIN2 | caprin family member 2 | 0.021395 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0212837 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0209801 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0208694 |
| AREG | amphiregulin | 0.0208136 |
| RNF213 | ring finger protein 213 | 0.0207808 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 0.0207457 |
| SMIM14 | small integral membrane protein 14 | 0.0206966 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0205172 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0204892 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0204137 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0203821 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.188424 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.178852 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.150116 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.139278 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.129858 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.115865 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.108894 |
| FLNB | filamin B, beta | -0.105988 |
| KLK10 | kallikrein-related peptidase 10 | -0.0956521 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0914716 |
| LAMB3 | laminin, beta 3 | -0.0912595 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0878998 |
| VIM | vimentin | -0.0720439 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0671426 |
| PGK1 | phosphoglycerate kinase 1 | -0.0623672 |
| ANXA2 | annexin A2 | -0.0605122 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0584146 |
| UBC | ubiquitin C | -0.0584041 |
| RPL35A | ribosomal protein L35a | -0.0565742 |
| LMO7 | LIM domain 7 | -0.0565646 |
| TPM4 | tropomyosin 4 | -0.0563819 |
| POTEF | POTE ankyrin domain family, member F | -0.0549076 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0533373 |
| ACTG1 | actin gamma 1 | -0.0522283 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0512263 |
| HMGA1 | high mobility group AT-hook 1 | -0.0510722 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0493332 |
| LDHA | lactate dehydrogenase A | -0.0487312 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0474379 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0450033 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0440157 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0428806 |
| MORF4L2 | mortality factor 4 like 2 | -0.0420681 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0411693 |
| S100A10 | S100 calcium binding protein A10 | -0.0410263 |
| S100A4 | S100 calcium binding protein A4 | -0.040723 |
| RPS24 | ribosomal protein S24 | -0.0403485 |
| S100A6 | S100 calcium binding protein A6 | -0.0402993 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0402171 |
| SQSTM1 | sequestosome 1 | -0.0397505 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0388607 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0382251 |
| LAMC2 | laminin, gamma 2 | -0.0380309 |
| FERMT1 | fermitin family member 1 | -0.037882 |
| CD2AP | CD2-associated protein | -0.0376141 |
| PERP | PERP, TP53 apoptosis effector | -0.037436 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0373178 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0371805 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0362679 |
| PTMA | prothymosin, alpha | -0.0357435 |
| TMEM165 | transmembrane protein 165 | -0.0351513 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0351309 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0346464 |
| CALU | calumenin | -0.0345046 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0343241 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0337535 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0336753 |
| KRT18 | keratin 18, type I | -0.0323475 |
| FTL | ferritin, light polypeptide | -0.0322674 |
| RPS27A | ribosomal protein S27a | -0.0318416 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.031552 |
| ARF4 | ADP-ribosylation factor 4 | -0.031541 |
| RPL34 | ribosomal protein L34 | -0.0312064 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0306392 |
| IER3 | immediate early response 3 | -0.0304934 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0304488 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0303786 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0302785 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0301504 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0298404 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0297921 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0290557 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0290371 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0288031 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0282988 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0278996 |
| RPLP1 | ribosomal protein, large, P1 | -0.0270136 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0268335 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0268268 |
| THBD | thrombomodulin | -0.0267461 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0265865 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0264513 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.026298 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0261049 |
| RPL11 | ribosomal protein L11 | -0.0260644 |
| MUC17 | mucin 17, cell surface associated | -0.0260443 |
| DIAPH2 | diaphanous-related formin 2 | -0.0259405 |
| COPA | coatomer protein complex, subunit alpha | -0.0258465 |
| KRT8 | keratin 8, type II | -0.0256229 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0253044 |
| LIMA1 | LIM domain and actin binding 1 | -0.0252929 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0249537 |
| FUS | FUS RNA binding protein | -0.0247065 |
| EPCAM | epithelial cell adhesion molecule | -0.0246577 |
| PLS3 | plastin 3 | -0.0244197 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0243519 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0243112 |
| OPTN | optineurin | -0.0239187 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0239141 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0238666 |
