| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.122188 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.107448 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0741735 |
| RPS2 | ribosomal protein S2 | 0.0731056 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0683671 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0635404 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0630861 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0560469 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0516114 |
| SET | SET nuclear proto-oncogene | 0.0497602 |
| HSPA8 | heat shock 70kDa protein 8 | 0.047959 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0468901 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0466817 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0431906 |
| RPS6 | ribosomal protein S6 | 0.0425199 |
| YBX1 | Y box binding protein 1 | 0.0416096 |
| DUSP16 | dual specificity phosphatase 16 | 0.0414982 |
| TPM3 | tropomyosin 3 | 0.0393261 |
| PNN | pinin, desmosome associated protein | 0.0386385 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0384777 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0358582 |
| GPHN | gephyrin | 0.0357196 |
| RPL4 | ribosomal protein L4 | 0.0347761 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0336884 |
| DSPP | dentin sialophosphoprotein | 0.0328938 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0318609 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0317589 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0314839 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0311178 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0304019 |
| NTN4 | netrin 4 | 0.0301669 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0298251 |
| EPHA4 | EPH receptor A4 | 0.0298132 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0294197 |
| CLTC | clathrin, heavy chain (Hc) | 0.0287244 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0286963 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0284176 |
| RPL13A | ribosomal protein L13a | 0.0279886 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0279365 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0278347 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0277977 |
| SMYD3 | SET and MYND domain containing 3 | 0.0274432 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0270794 |
| SLFN5 | schlafen family member 5 | 0.0265262 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0261366 |
| NRP1 | neuropilin 1 | 0.0256431 |
| MBD4 | methyl-CpG binding domain protein 4 | 0.0253571 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0249902 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0242815 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0242745 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0239901 |
| GNAS | GNAS complex locus | 0.0237613 |
| TFF1 | trefoil factor 1 | 0.0234217 |
| TUBA1B | tubulin, alpha 1b | 0.0234041 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0232034 |
| SKA2 | spindle and kinetochore associated complex subunit 2 | 0.0227126 |
| MED13L | mediator complex subunit 13-like | 0.0226705 |
| TXNRD1 | thioredoxin reductase 1 | 0.0226144 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0225128 |
| MLEC | malectin | 0.0224672 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0220583 |
| IGF2 | insulin-like growth factor 2 | 0.0220109 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0218234 |
| KIF5B | kinesin family member 5B | 0.0217344 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0216688 |
| SMAD3 | SMAD family member 3 | 0.0215735 |
| RND3 | Rho family GTPase 3 | 0.021471 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0214702 |
| SYAP1 | synapse associated protein 1 | 0.0214281 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0214218 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0214146 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0214145 |
| YBX3 | Y box binding protein 3 | 0.0213696 |
| CANX | calnexin | 0.0212545 |
| PTMA | prothymosin, alpha | 0.0210574 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0210501 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.020974 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0208532 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0206897 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0204417 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0204215 |
| MT2A | metallothionein 2A | 0.0204124 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0203691 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0203612 |
| SEPTIN9 | septin 9 | 0.0201998 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.0201786 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0200641 |
| RPS12 | ribosomal protein S12 | 0.02001 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0199945 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0197792 |
| MYO10 | myosin X | 0.01976 |
| FGB | fibrinogen beta chain | 0.0197345 |
| MYO1B | myosin IB | 0.0194291 |
| TMSB4X | thymosin beta 4, X-linked | 0.0193226 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0191478 |
| RPS17 | ribosomal protein S17 | 0.0190724 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0190589 |
| RPS19 | ribosomal protein S19 | 0.0189188 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0187962 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0186576 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.206777 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.168567 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.133901 |
| ACACA | acetyl-CoA carboxylase alpha | -0.128386 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.098888 |
| LASP1 | LIM and SH3 protein 1 | -0.0952925 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0876088 |
| VMP1 | vacuole membrane protein 1 | -0.0713549 |
| ASPH | aspartate beta-hydroxylase | -0.0675542 |
| FADS2 | fatty acid desaturase 2 | -0.0597678 |
| NDRG1 | N-myc downstream regulated 1 | -0.0590845 |
| TMSB10 | thymosin beta 10 | -0.0580647 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0552348 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0506037 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0491831 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0490431 |
| POTEF | POTE ankyrin domain family, member F | -0.047893 |
| TMEM123 | transmembrane protein 123 | -0.046045 |
| PGK1 | phosphoglycerate kinase 1 | -0.0459035 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0458643 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0442674 |
| JMJD1C | jumonji domain containing 1C | -0.0430983 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0425666 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.042234 |
| RPL23 | ribosomal protein L23 | -0.0407928 |
| ZNF652 | zinc finger protein 652 | -0.0399788 |
| RAB6A | RAB6A, member RAS oncogene family | -0.039092 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0388385 |
| LDHA | lactate dehydrogenase A | -0.0372042 |
| INSIG1 | insulin induced gene 1 | -0.036627 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0365403 |
| MCL1 | myeloid cell leukemia 1 | -0.0362349 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0362018 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.0355109 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0349688 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0342727 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0342036 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0336519 |
| DST | dystonin | -0.0335603 |
| KRT19 | keratin 19, type I | -0.0332908 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.032371 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0322084 |
| LMNA | lamin A/C | -0.032152 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0318926 |
| FASN | fatty acid synthase | -0.0308499 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0304562 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0299566 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0299563 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0291649 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0288852 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0284536 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0280971 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0275507 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0272735 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0272399 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0268777 |
| KIF16B | kinesin family member 16B | -0.0266979 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0266484 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0266269 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.026151 |
| KRT8 | keratin 8, type II | -0.0258816 |
| CCNI | cyclin I | -0.0256267 |
| CEP250 | centrosomal protein 250kDa | -0.0255393 |
| DENND1B | DENN/MADD domain containing 1B | -0.0251872 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0245037 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0242962 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0242314 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0241374 |
| MIEN1 | migration and invasion enhancer 1 | -0.0239732 |
| SRPK2 | SRSF protein kinase 2 | -0.0239366 |
| TMEM41B | transmembrane protein 41B | -0.0238283 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0233488 |
| RESF1 | retroelement silencing factor 1 | -0.0233158 |
| MYO5B | myosin VB | -0.0232401 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0231993 |
| CD164 | CD164 molecule, sialomucin | -0.0231286 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.0229158 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0228833 |
| YPEL2 | yippee-like 2 (Drosophila) | -0.0228654 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0226529 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0224682 |
| PKM | pyruvate kinase, muscle | -0.0223741 |
| KLC1 | kinesin light chain 1 | -0.022133 |
| SQLE | squalene epoxidase | -0.0221171 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0219717 |
| FDPS | farnesyl diphosphate synthase | -0.0219084 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0219029 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0216375 |
| WASF2 | WAS protein family, member 2 | -0.0215338 |
| TMEM135 | transmembrane protein 135 | -0.0214488 |
| KRT7 | keratin 7, type II | -0.0212562 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0212494 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0212437 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0212349 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0212047 |
| TAOK3 | TAO kinase 3 | -0.0209243 |
| COPA | coatomer protein complex, subunit alpha | -0.0208242 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0206868 |
| S100P | S100 calcium binding protein P | -0.0203028 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0202653 |
