| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0967837 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.060754 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0603552 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0594578 |
| UBAP2 | ubiquitin associated protein 2 | 0.0564382 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0563602 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0544522 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0519296 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0509148 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0508324 |
| CENPF | centromere protein F, 350/400kDa | 0.0503503 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0498849 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0485221 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0480691 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0458729 |
| RPS6 | ribosomal protein S6 | 0.0456477 |
| PNN | pinin, desmosome associated protein | 0.0453979 |
| JMJD1C | jumonji domain containing 1C | 0.0449398 |
| RCOR1 | REST corepressor 1 | 0.0438824 |
| PCBP2 | poly(rC) binding protein 2 | 0.0438009 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0432887 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0428775 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0426896 |
| RPS2 | ribosomal protein S2 | 0.0416055 |
| COL5A2 | collagen, type V, alpha 2 | 0.041433 |
| SIK3 | SIK family kinase 3 | 0.0413756 |
| DST | dystonin | 0.0411819 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0409849 |
| ZNF608 | zinc finger protein 608 | 0.0392744 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0385222 |
| BPTF | bromodomain PHD finger transcription factor | 0.0371923 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0369768 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0363747 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0361531 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0360307 |
| TPM3 | tropomyosin 3 | 0.035878 |
| BRD4 | bromodomain containing 4 | 0.0355615 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0354638 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0354303 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0352298 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0351193 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.034968 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0346502 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0343568 |
| AUTS2 | autism susceptibility candidate 2 | 0.0341791 |
| FNBP1 | formin binding protein 1 | 0.0340614 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.033933 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0339223 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0338804 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0337506 |
| WLS | wntless Wnt ligand secretion mediator | 0.033487 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0334654 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0329923 |
| BBX | bobby sox homolog (Drosophila) | 0.032635 |
| PDS5A | PDS5 cohesin associated factor A | 0.0316671 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.0314499 |
| JUN | jun proto-oncogene | 0.0311346 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0309908 |
| TCF12 | transcription factor 12 | 0.0305692 |
| SETD5 | SET domain containing 5 | 0.0304764 |
| PCM1 | pericentriolar material 1 | 0.0304346 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0299228 |
| CDK13 | cyclin-dependent kinase 13 | 0.0296738 |
| MKI67 | marker of proliferation Ki-67 | 0.0293023 |
| HELLS | helicase, lymphoid-specific | 0.0291451 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0291261 |
| NBEAL1 | neurobeachin-like 1 | 0.0290082 |
| ATXN2 | ataxin 2 | 0.0289652 |
| MMS22L | MMS22-like, DNA repair protein | 0.0288427 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0287472 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0281213 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.027996 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0279791 |
| ZNF609 | zinc finger protein 609 | 0.0278529 |
| EXOC4 | exocyst complex component 4 | 0.0278435 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0278387 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.02777 |
| SETD2 | SET domain containing 2 | 0.0276228 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0275618 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0275149 |
| SSH2 | slingshot protein phosphatase 2 | 0.0274042 |
| TOB2 | transducer of ERBB2, 2 | 0.0273237 |
| RANBP17 | RAN binding protein 17 | 0.0271265 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0266366 |
| PAPOLA | poly(A) polymerase alpha | 0.0264698 |
| ATXN7 | ataxin 7 | 0.0263991 |
| PHF21A | PHD finger protein 21A | 0.026308 |
| GOLGB1 | golgin B1 | 0.0261812 |
| MED13 | mediator complex subunit 13 | 0.0260823 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.026078 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0259748 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0258017 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0256715 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0252821 |
| SRPK2 | SRSF protein kinase 2 | 0.0252612 |
| NRDC | nardilysin convertase | 0.0252152 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0252032 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0251937 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0251668 |
| SYAP1 | synapse associated protein 1 | 0.0251581 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPAS3 | neuronal PAS domain protein 3 | -0.174045 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.11003 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0901843 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0885612 |
| ACTG1 | actin gamma 1 | -0.0873548 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0856764 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0850743 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0780445 |
| RPS24 | ribosomal protein S24 | -0.0691595 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0679009 |
| RAD51B | RAD51 paralog B | -0.0665815 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0661312 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0655974 |
| RPL11 | ribosomal protein L11 | -0.0641865 |
| TENM3 | teneurin transmembrane protein 3 | -0.0621607 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0608607 |
| SHROOM3 | shroom family member 3 | -0.058756 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0572455 |
| LDHA | lactate dehydrogenase A | -0.0568282 |
| H1-0 | H1.0 linker histone | -0.0566014 |
| RPS8 | ribosomal protein S8 | -0.0562293 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0543686 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0522486 |
| PGK1 | phosphoglycerate kinase 1 | -0.052224 |
| B2M | beta-2-microglobulin | -0.0519181 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0518395 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0494746 |
| RPLP0 | ribosomal protein, large, P0 | -0.0490081 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0488713 |
| RPS4X | ribosomal protein S4, X-linked | -0.0484767 |
| RPL26 | ribosomal protein L26 | -0.046319 |
| RPL34 | ribosomal protein L34 | -0.0457349 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.045321 |
| ZNF217 | zinc finger protein 217 | -0.0447673 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0430421 |
| TMSB10 | thymosin beta 10 | -0.0421199 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0416616 |
| RPL31 | ribosomal protein L31 | -0.0414193 |
| CADM2 | cell adhesion molecule 2 | -0.0413898 |
| WDR45B | WD repeat domain 45B | -0.0402175 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0394728 |
| FAM162A | family with sequence similarity 162, member A | -0.0390269 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.03749 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0372023 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0369473 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0368373 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0362559 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0351918 |
| RPL35A | ribosomal protein L35a | -0.0348763 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0348402 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0344254 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0343087 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0341097 |
| ENO1 | enolase 1, (alpha) | -0.0339725 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.033271 |
| ANXA2 | annexin A2 | -0.0327956 |
| RPL23 | ribosomal protein L23 | -0.0327307 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0326977 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0326634 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0316747 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0316456 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0309174 |
| RPS3 | ribosomal protein S3 | -0.0307388 |
| RPLP1 | ribosomal protein, large, P1 | -0.030657 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0299266 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.029865 |
| RPL38 | ribosomal protein L38 | -0.0294007 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0293726 |
| RPL37A | ribosomal protein L37a | -0.0291469 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0287659 |
| TXNRD1 | thioredoxin reductase 1 | -0.0285629 |
| CDH18 | cadherin 18, type 2 | -0.0283158 |
| MT2A | metallothionein 2A | -0.0281164 |
| ZNF770 | zinc finger protein 770 | -0.028043 |
| EFNA5 | ephrin-A5 | -0.0279673 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0272996 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | -0.0272029 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0268296 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0266771 |
| XPO7 | exportin 7 | -0.026502 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0261828 |
| RPL9 | ribosomal protein L9 | -0.0260622 |
| HMGB1 | high mobility group box 1 | -0.025993 |
| PTMA | prothymosin, alpha | -0.0258465 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0258454 |
| RPS27A | ribosomal protein S27a | -0.0258302 |
| RPL36 | ribosomal protein L36 | -0.0257067 |
| RPS19 | ribosomal protein S19 | -0.025549 |
| SEPTIN7 | septin 7 | -0.0254167 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0249829 |
| CCNI | cyclin I | -0.0249769 |
| RPS28 | ribosomal protein S28 | -0.0249332 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0246808 |
| ZNF33A | zinc finger protein 33A | -0.0246695 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0243628 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0243143 |
| RPS29 | ribosomal protein S29 | -0.0241326 |
| HLA-C | major histocompatibility complex, class I, C | -0.023923 |
| CAVIN1 | caveolae associated protein 1 | -0.0238025 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0235545 |
