| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.280377 |
| PTCHD4 | patched domain containing 4 | 0.131888 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0986421 |
| GDF15 | growth differentiation factor 15 | 0.0932828 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0930167 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0839857 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0799292 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0731734 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0664574 |
| FMN1 | formin 1 | 0.0655671 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0640204 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0637003 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0594438 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0556463 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0533214 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0530766 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0446195 |
| SFTPA2 | surfactant protein A2 | 0.0425874 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0407271 |
| CD109 | CD109 molecule | 0.0395003 |
| CANX | calnexin | 0.0393599 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0391739 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0384998 |
| HLA-E | major histocompatibility complex, class I, E | 0.0372459 |
| JUN | jun proto-oncogene | 0.035003 |
| FRMD4A | FERM domain containing 4A | 0.0336205 |
| SDC2 | syndecan 2 | 0.0333308 |
| RGS12 | regulator of G-protein signaling 12 | 0.0310914 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0310574 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.030743 |
| HMGA2 | high mobility group AT-hook 2 | 0.0299627 |
| HLA-B | major histocompatibility complex, class I, B | 0.029401 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0283528 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0280116 |
| RBM39 | RNA binding motif protein 39 | 0.0279877 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0276702 |
| CALR | calreticulin | 0.0270153 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0257927 |
| EGR1 | early growth response 1 | 0.0252742 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0249286 |
| ITGB8 | integrin, beta 8 | 0.0247981 |
| ZC3H7A | zinc finger CCCH-type containing 7A | 0.0245983 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0244603 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0244447 |
| RPS2 | ribosomal protein S2 | 0.0242305 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0241078 |
| GOLGA4 | golgin A4 | 0.0237981 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0236846 |
| LRRC23 | leucine rich repeat containing 23 | 0.0236573 |
| PARVB | parvin, beta | 0.0234681 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0234214 |
| TEX14 | testis expressed 14 | 0.0232908 |
| STXBP1 | syntaxin binding protein 1 | 0.0227387 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.02264 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.022619 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0225514 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0225009 |
| SERINC5 | serine incorporator 5 | 0.0223597 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0216706 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0213455 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.021114 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0207889 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0207605 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.0201071 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0200704 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0200448 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.01978 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0193375 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0192996 |
| A2M | alpha-2-macroglobulin | 0.0192862 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0191156 |
| GTF2B | general transcription factor IIB | 0.0189519 |
| TAFA2 | TAFA chemokine like family member 2 | 0.0189076 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0188821 |
| TPM3 | tropomyosin 3 | 0.0188501 |
| PLK2 | polo-like kinase 2 | 0.0187921 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0187803 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.0187345 |
| SVIL | supervillin | 0.0185075 |
| SEC24A | SEC24 family member A | 0.0182309 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.018228 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0180134 |
| SSH1 | slingshot protein phosphatase 1 | 0.0179464 |
| HLA-A | major histocompatibility complex, class I, A | 0.0178595 |
| YBX3 | Y box binding protein 3 | 0.0176325 |
| EP300 | E1A binding protein p300 | 0.0175974 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0174914 |
| GOLGB1 | golgin B1 | 0.0173516 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 0.0172615 |
| VCL | vinculin | 0.0172431 |
| PI15 | peptidase inhibitor 15 | 0.0171514 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0170894 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0170755 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0170422 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.017038 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0168406 |
| FBXO7 | F-box protein 7 | 0.0164767 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0164552 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0163646 |
| VMP1 | vacuole membrane protein 1 | 0.0162539 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.236836 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171225 |
| FN1 | fibronectin 1 | -0.164795 |
| NLGN1 | neuroligin 1 | -0.128687 |
| CENPF | centromere protein F, 350/400kDa | -0.113673 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0959306 |
| NAV2 | neuron navigator 2 | -0.0952484 |
| VIM | vimentin | -0.0777909 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0753969 |
| POTEF | POTE ankyrin domain family, member F | -0.0731171 |
| ASPH | aspartate beta-hydroxylase | -0.0726681 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0648466 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.062204 |
| TMSB10 | thymosin beta 10 | -0.0600069 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0585011 |
| NDRG1 | N-myc downstream regulated 1 | -0.057927 |
| TAGLN2 | transgelin 2 | -0.0561212 |
| MACROD2 | MACRO domain containing 2 | -0.0539354 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0502359 |
| TMEM178B | transmembrane protein 178B | -0.0494286 |
| PRELID2 | PRELI domain containing 2 | -0.0477656 |
| MT1X | metallothionein 1X | -0.0476187 |
| NAV1 | neuron navigator 1 | -0.0472971 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0466367 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0464732 |
| CDK14 | cyclin-dependent kinase 14 | -0.0461229 |
| PTK2 | protein tyrosine kinase 2 | -0.0449894 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0431097 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0424518 |
| PCDH7 | protocadherin 7 | -0.0415148 |
| ACTG1 | actin gamma 1 | -0.0413068 |
| SRPK2 | SRSF protein kinase 2 | -0.0403933 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0394753 |
| MEF2A | myocyte enhancer factor 2A | -0.0394171 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0383494 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0382182 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | -0.0377397 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0369951 |
| ATXN1 | ataxin 1 | -0.0360711 |
| LOC112694756 | uncharaterized LOC112694756 | -0.035945 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.035562 |
| MKI67 | marker of proliferation Ki-67 | -0.0347398 |
| CD44 | CD44 molecule (Indian blood group) | -0.0338256 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0322574 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0322447 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0320446 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0317965 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0314394 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0310157 |
| CALD1 | caldesmon 1 | -0.0309981 |
| TNNC1 | troponin C type 1 (slow) | -0.0309584 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0305165 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0303302 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0300859 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0300385 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0300016 |
| HMGA1 | high mobility group AT-hook 1 | -0.0298158 |
| NBAS | neuroblastoma amplified sequence | -0.0295974 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0294126 |
| DCT | dopachrome tautomerase | -0.0292355 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0292255 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0288784 |
| SGO2 | shugoshin 2 | -0.0288441 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0288206 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0284399 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0284202 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0282617 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280683 |
| NEGR1 | neuronal growth regulator 1 | -0.0279756 |
| NHSL1 | NHS-like 1 | -0.0277874 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0276185 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0274674 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0274421 |
| CABIN1 | calcineurin binding protein 1 | -0.027394 |
| LDHA | lactate dehydrogenase A | -0.0271977 |
| TPD52 | tumor protein D52 | -0.0270939 |
| RPL19 | ribosomal protein L19 | -0.0269901 |
| CENPE | centromere protein E, 312kDa | -0.0268209 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.026377 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0262341 |
| SEPTIN7 | septin 7 | -0.0262017 |
| PGK1 | phosphoglycerate kinase 1 | -0.0261822 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0258416 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0257575 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0254086 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.02493 |
| SMAD3 | SMAD family member 3 | -0.0245685 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0245591 |
| EHBP1 | EH domain binding protein 1 | -0.0245305 |
| TRIM2 | tripartite motif containing 2 | -0.0245222 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | -0.0244413 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.024314 |
| RFX7 | regulatory factor X, 7 | -0.024244 |
| SETD5 | SET domain containing 5 | -0.0241089 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0239494 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0238936 |
| ACTN4 | actinin, alpha 4 | -0.0238344 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0235876 |
| KIF14 | kinesin family member 14 | -0.0231498 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0231289 |
