| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0749068 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0618901 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0535223 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0534734 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0485894 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0418271 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0402692 |
| RPS2 | ribosomal protein S2 | 0.0388726 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0383523 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0378162 |
| RPS6 | ribosomal protein S6 | 0.0350602 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0345865 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0334136 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0325821 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0319322 |
| LAMB3 | laminin, beta 3 | 0.0316011 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0303185 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0299116 |
| GOLGB1 | golgin B1 | 0.0297513 |
| EREG | epiregulin | 0.029666 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0296298 |
| RPL4 | ribosomal protein L4 | 0.0294833 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0294517 |
| CFB | complement factor B | 0.0280397 |
| DSPP | dentin sialophosphoprotein | 0.0273085 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0272777 |
| PHF3 | PHD finger protein 3 | 0.0272728 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.026737 |
| EPAS1 | endothelial PAS domain protein 1 | 0.026668 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0258333 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0246988 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0246875 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.024437 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0242914 |
| KYNU | kynureninase | 0.0241497 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.023757 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.022893 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0228891 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0220403 |
| FGB | fibrinogen beta chain | 0.0218813 |
| HLA-E | major histocompatibility complex, class I, E | 0.0216436 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0214356 |
| RND3 | Rho family GTPase 3 | 0.0207713 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0207465 |
| ATF3 | activating transcription factor 3 | 0.0204192 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0201302 |
| CEP44 | centrosomal protein 44kDa | 0.0199941 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0199564 |
| SRP54 | signal recognition particle 54kDa | 0.0197927 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0197599 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0195176 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0194565 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0194493 |
| TMC5 | transmembrane channel-like 5 | 0.0192499 |
| BARX2 | BARX homeobox 2 | 0.0188447 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0185881 |
| DSCAM | Down syndrome cell adhesion molecule | 0.018581 |
| SMAD3 | SMAD family member 3 | 0.0185095 |
| TPM3 | tropomyosin 3 | 0.0184816 |
| IL6 | interleukin 6 | 0.0183632 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0181307 |
| SYNRG | synergin, gamma | 0.0181226 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0180531 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0173525 |
| LCN2 | lipocalin 2 | 0.0173462 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0172024 |
| BRD2 | bromodomain containing 2 | 0.0170744 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0169925 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0168941 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0167557 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0166796 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0162745 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 0.0162211 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0159712 |
| SIRT1 | sirtuin 1 | 0.0158533 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0158314 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0157241 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0155097 |
| CANX | calnexin | 0.0151822 |
| RPS12 | ribosomal protein S12 | 0.0148195 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.014739 |
| KIF5B | kinesin family member 5B | 0.0147043 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0146742 |
| GOLGA4 | golgin A4 | 0.0146658 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0146322 |
| SLU7 | SLU7 splicing factor homolog (S. cerevisiae) | 0.014545 |
| SERINC5 | serine incorporator 5 | 0.0144198 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.014166 |
| MEIS1 | Meis homeobox 1 | 0.0140921 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0140356 |
| MT1G | metallothionein 1G | 0.0138686 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0137306 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0136625 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0136343 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0135576 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0135527 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0135482 |
| DUOX2 | dual oxidase 2 | 0.0134783 |
| MYO10 | myosin X | 0.0133799 |
| RPL13A | ribosomal protein L13a | 0.0133342 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.265776 |
| KRT19 | keratin 19, type I | -0.165847 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.164983 |
| POTEF | POTE ankyrin domain family, member F | -0.141274 |
| PTMA | prothymosin, alpha | -0.130935 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.122661 |
| ENO1 | enolase 1, (alpha) | -0.120817 |
| ACTG1 | actin gamma 1 | -0.118207 |
| S100A6 | S100 calcium binding protein A6 | -0.117243 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.115722 |
| NDRG1 | N-myc downstream regulated 1 | -0.108626 |
| VIM | vimentin | -0.101582 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0985201 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.096744 |
| MMP7 | matrix metallopeptidase 7 | -0.0937066 |
| ANXA2 | annexin A2 | -0.0933297 |
| HMGA1 | high mobility group AT-hook 1 | -0.0892125 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0846063 |
| PKM | pyruvate kinase, muscle | -0.0818613 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0811927 |
| ITGA6 | integrin, alpha 6 | -0.0789179 |
| MT1X | metallothionein 1X | -0.0781854 |
| PGK1 | phosphoglycerate kinase 1 | -0.0768675 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0714728 |
| B2M | beta-2-microglobulin | -0.070707 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0699445 |
| MAP1B | microtubule-associated protein 1B | -0.0688627 |
| LDHA | lactate dehydrogenase A | -0.065969 |
| ASPH | aspartate beta-hydroxylase | -0.065631 |
| LAMA4 | laminin, alpha 4 | -0.0598123 |
| PLAT | plasminogen activator, tissue | -0.0584467 |
| S100A10 | S100 calcium binding protein A10 | -0.0583109 |
| UBC | ubiquitin C | -0.056329 |
| MEF2A | myocyte enhancer factor 2A | -0.0551806 |
| TMSB4X | thymosin beta 4, X-linked | -0.0545972 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0545 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0542365 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0532101 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0528006 |
| MT2A | metallothionein 2A | -0.0524838 |
| ACTN4 | actinin, alpha 4 | -0.0516056 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0511304 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0498803 |
| FTL | ferritin, light polypeptide | -0.0496206 |
| TPM4 | tropomyosin 4 | -0.0494556 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.049418 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0482726 |
| RPL35A | ribosomal protein L35a | -0.0468204 |
| RPL23 | ribosomal protein L23 | -0.0464973 |
| LAMC2 | laminin, gamma 2 | -0.0464041 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0457871 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.045659 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0447241 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0440959 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0438173 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0437571 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0434228 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0430481 |
| TAGLN2 | transgelin 2 | -0.0424897 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0419381 |
| MYOF | myoferlin | -0.0417612 |
| VCL | vinculin | -0.0414774 |
| KRT8 | keratin 8, type II | -0.0410532 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0409425 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0406455 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0403502 |
| CD2AP | CD2-associated protein | -0.0402937 |
| FLNB | filamin B, beta | -0.0392049 |
| PDLIM5 | PDZ and LIM domain 5 | -0.038987 |
| APOL1 | apolipoprotein L, 1 | -0.0388242 |
| EHBP1 | EH domain binding protein 1 | -0.0386658 |
| PLAU | plasminogen activator, urokinase | -0.0380301 |
| PARD3 | par-3 family cell polarity regulator | -0.0379826 |
| NRG3 | neuregulin 3 | -0.0379461 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.037839 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0373261 |
| PRKCA | protein kinase C, alpha | -0.0370631 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0366212 |
| MCU | mitochondrial calcium uniporter | -0.0364793 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0362718 |
| CDK6 | cyclin-dependent kinase 6 | -0.0362282 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0361786 |
| RPL19 | ribosomal protein L19 | -0.0360534 |
| RPS24 | ribosomal protein S24 | -0.0359694 |
| CD47 | CD47 molecule | -0.0352209 |
| TPM1 | tropomyosin 1 (alpha) | -0.0351362 |
| KRT18 | keratin 18, type I | -0.0351175 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0350788 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0349746 |
| DST | dystonin | -0.0349027 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0348233 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0346005 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0344914 |
| NCKAP5 | NCK-associated protein 5 | -0.0344193 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0340762 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.033133 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0329367 |
| RASAL2 | RAS protein activator like 2 | -0.0327794 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0325807 |
| FAM162A | family with sequence similarity 162, member A | -0.0325666 |
