| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.101211 |
| RPS6 | ribosomal protein S6 | 0.0662259 |
| PLAT | plasminogen activator, tissue | 0.0601873 |
| VCL | vinculin | 0.0490806 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.046765 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0432501 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0417147 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0375003 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0372082 |
| CDH13 | cadherin 13 | 0.0366862 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.033376 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0331344 |
| HMGA2 | high mobility group AT-hook 2 | 0.0323698 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0309693 |
| COL5A1 | collagen, type V, alpha 1 | 0.0306873 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0305376 |
| FMN1 | formin 1 | 0.0300647 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.029563 |
| VMP1 | vacuole membrane protein 1 | 0.0294017 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0293472 |
| RAD51B | RAD51 paralog B | 0.0287821 |
| RPS8 | ribosomal protein S8 | 0.0287788 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0284558 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0283045 |
| TF | transferrin | 0.0272145 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0265195 |
| SEPTIN9 | septin 9 | 0.0261202 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0260446 |
| MYO10 | myosin X | 0.0259591 |
| CD44 | CD44 molecule (Indian blood group) | 0.0259542 |
| TPM3 | tropomyosin 3 | 0.0254179 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0253341 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0252939 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.025151 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0250766 |
| RPS12 | ribosomal protein S12 | 0.0248253 |
| SETX | senataxin | 0.0239116 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0237973 |
| MT2A | metallothionein 2A | 0.0235899 |
| PDGFC | platelet derived growth factor C | 0.023466 |
| STC1 | stanniocalcin 1 | 0.0232374 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0230692 |
| ANTXR1 | anthrax toxin receptor 1 | 0.022846 |
| EGR1 | early growth response 1 | 0.0228243 |
| RPS17 | ribosomal protein S17 | 0.0226153 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0225787 |
| PCBP3 | poly(rC) binding protein 3 | 0.0225525 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0224393 |
| TEX14 | testis expressed 14 | 0.0224051 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.022359 |
| RPS25 | ribosomal protein S25 | 0.0221605 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0221232 |
| FERMT2 | fermitin family member 2 | 0.021955 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0219201 |
| CLIC4 | chloride intracellular channel 4 | 0.0219095 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0218702 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0215157 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0213459 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0211924 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0211236 |
| DUSP10 | dual specificity phosphatase 10 | 0.0210621 |
| FN1 | fibronectin 1 | 0.0209775 |
| MEF2D | myocyte enhancer factor 2D | 0.0208216 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0208081 |
| RAI14 | retinoic acid induced 14 | 0.0205187 |
| CUX1 | cut-like homeobox 1 | 0.0202933 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0202704 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0199526 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0199327 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0198844 |
| RNF38 | ring finger protein 38 | 0.0197105 |
| NLGN4Y | neuroligin 4, Y-linked | 0.0194644 |
| FAT1 | FAT atypical cadherin 1 | 0.0194293 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0193863 |
| EEA1 | early endosome antigen 1 | 0.0193749 |
| RPS2 | ribosomal protein S2 | 0.0191444 |
| AEBP2 | AE binding protein 2 | 0.019117 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0190027 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.01893 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0189248 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0188651 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.018829 |
| PCNX4 | pecanex 4 | 0.0186164 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0185879 |
| EVI5 | ecotropic viral integration site 5 | 0.018561 |
| NCOA1 | nuclear receptor coactivator 1 | 0.018523 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0184665 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.018427 |
| DSPP | dentin sialophosphoprotein | 0.0183644 |
| POLH | polymerase (DNA directed), eta | 0.0182944 |
| UNK | unkempt family zinc finger | 0.0182247 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0181889 |
| NHSL1 | NHS-like 1 | 0.018187 |
| TAFA2 | TAFA chemokine like family member 2 | 0.0181713 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0179062 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.01788 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0178229 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0176183 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0175728 |
| TES | testin LIM domain protein | 0.0175351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.575488 |
| IGF2 | insulin-like growth factor 2 | -0.135733 |
| MEIS2 | Meis homeobox 2 | -0.107612 |
| VIM | vimentin | -0.0985724 |
| TRIB2 | tribbles pseudokinase 2 | -0.0893019 |
| MAP1B | microtubule-associated protein 1B | -0.0840932 |
| LSAMP | limbic system-associated membrane protein | -0.0805583 |
| LPIN1 | lipin 1 | -0.0805331 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0695238 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0669867 |
| PCDH9 | protocadherin 9 | -0.0655258 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0639789 |
| RPL23 | ribosomal protein L23 | -0.0567374 |
| PTMA | prothymosin, alpha | -0.0562181 |
| SYT1 | synaptotagmin I | -0.0536361 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0506092 |
| OGA | O-GlcNAcase | -0.0461884 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0456522 |
| RPL19 | ribosomal protein L19 | -0.0453311 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0445791 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0438998 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0436267 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0423646 |
| HELZ | helicase with zinc finger | -0.0420144 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0413617 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0411522 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0407966 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0399581 |
| COL3A1 | collagen, type III, alpha 1 | -0.0395913 |
| CDC27 | cell division cycle 27 | -0.0387547 |
| H3-3B | H3.3 histone B | -0.0374075 |
| KLHL13 | kelch-like family member 13 | -0.0373471 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0365648 |
| PRKCA | protein kinase C, alpha | -0.0360926 |
| ZNF292 | zinc finger protein 292 | -0.0359128 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0355985 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.035023 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0349643 |
| RPL38 | ribosomal protein L38 | -0.034836 |
| SPAG9 | sperm associated antigen 9 | -0.0341301 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0337049 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0336855 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0334486 |
| CCDC47 | coiled-coil domain containing 47 | -0.0322823 |
| ANGPT1 | angiopoietin 1 | -0.0320323 |
| NREP | neuronal regeneration related protein | -0.031954 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0315269 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0310169 |
| MATR3 | matrin 3 | -0.030987 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0306128 |
| DPH6 | diphthamine biosynthesis 6 | -0.0305284 |
| NRG1 | neuregulin 1 | -0.030236 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0296939 |
| BBX | bobby sox homolog (Drosophila) | -0.0295218 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0294569 |
| RPL35A | ribosomal protein L35a | -0.0294393 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0293934 |
| ACTG1 | actin gamma 1 | -0.0293342 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0292274 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0291272 |
| MYO6 | myosin VI | -0.0288691 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.028745 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0286618 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0282688 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0281773 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0280546 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0279659 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0279455 |
| FAM162A | family with sequence similarity 162, member A | -0.0275002 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0272015 |
| ADAR | adenosine deaminase, RNA-specific | -0.0270345 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0269455 |
| FTL | ferritin, light polypeptide | -0.0265988 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0260703 |
| COL1A1 | collagen, type I, alpha 1 | -0.0259112 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0256657 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0253961 |
| CENPF | centromere protein F, 350/400kDa | -0.025075 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0248617 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0248206 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0247818 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0247597 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0245822 |
| PANK3 | pantothenate kinase 3 | -0.0243099 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0242834 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0240413 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0239374 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0239322 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0238444 |
| CCNI | cyclin I | -0.0235422 |
| CLTC | clathrin, heavy chain (Hc) | -0.0234481 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.023302 |
| OLA1 | Obg-like ATPase 1 | -0.023245 |
| SEPTIN7 | septin 7 | -0.0231316 |
| WDR45B | WD repeat domain 45B | -0.0230935 |
| RAB30 | RAB30, member RAS oncogene family | -0.0229839 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0227934 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0227388 |
| TANK | TRAF family member-associated NFKB activator | -0.0225874 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0224613 |
