| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.242723 |
| LCN2 | lipocalin 2 | 0.114698 |
| MACC1 | metastasis associated in colon cancer 1 | 0.102673 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0955171 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0873822 |
| EGR1 | early growth response 1 | 0.0796644 |
| EZR | ezrin | 0.0761761 |
| TJP1 | tight junction protein 1 | 0.0752133 |
| MYO1E | myosin IE | 0.0720966 |
| MX2 | MX dynamin-like GTPase 2 | 0.0647348 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0633431 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0596322 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0589212 |
| AREG | amphiregulin | 0.0531648 |
| TXNRD1 | thioredoxin reductase 1 | 0.0526377 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0504908 |
| TMC5 | transmembrane channel-like 5 | 0.0503384 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0500934 |
| MUC13 | mucin 13, cell surface associated | 0.0495173 |
| MLPH | melanophilin | 0.04727 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0466348 |
| ANXA2 | annexin A2 | 0.04494 |
| BCL2L1 | BCL2-like 1 | 0.0442838 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0429604 |
| YBX3 | Y box binding protein 3 | 0.0424152 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0415799 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0411048 |
| SEPTIN9 | septin 9 | 0.0385812 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0381538 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0376105 |
| ETV6 | ets variant 6 | 0.0375761 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0373777 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0372237 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0364324 |
| DIAPH1 | diaphanous-related formin 1 | 0.0352544 |
| RND3 | Rho family GTPase 3 | 0.0348594 |
| EFNB2 | ephrin-B2 | 0.0344259 |
| TRERF1 | transcriptional regulating factor 1 | 0.0342991 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0338331 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0333702 |
| VMP1 | vacuole membrane protein 1 | 0.0327675 |
| ITGA6 | integrin, alpha 6 | 0.0324816 |
| RPS6 | ribosomal protein S6 | 0.031606 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0314139 |
| DSPP | dentin sialophosphoprotein | 0.030837 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0308253 |
| CCNL1 | cyclin L1 | 0.0306747 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.030409 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0303864 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0300673 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0297555 |
| SDC4 | syndecan 4 | 0.0296974 |
| RPS2 | ribosomal protein S2 | 0.02924 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0287826 |
| JUN | jun proto-oncogene | 0.0283972 |
| IL6ST | interleukin 6 signal transducer | 0.0283117 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0281091 |
| FHL2 | four and a half LIM domains 2 | 0.0277198 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0276409 |
| IFNGR1 | interferon gamma receptor 1 | 0.0273799 |
| TPM3 | tropomyosin 3 | 0.0272023 |
| PHF3 | PHD finger protein 3 | 0.0271857 |
| SLK | STE20-like kinase | 0.0270008 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0268921 |
| MYO5B | myosin VB | 0.0264323 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.026253 |
| ZNF292 | zinc finger protein 292 | 0.0260571 |
| LIPH | lipase, member H | 0.0259747 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0259356 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0258435 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0253095 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.02511 |
| APOL1 | apolipoprotein L, 1 | 0.024995 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.024899 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0248792 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0248641 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0248022 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0245918 |
| FAT1 | FAT atypical cadherin 1 | 0.0245893 |
| PDZD8 | PDZ domain containing 8 | 0.0245544 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0243706 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0243701 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0238794 |
| SMAD3 | SMAD family member 3 | 0.023808 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0237202 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0235677 |
| JMJD1C | jumonji domain containing 1C | 0.0235321 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0233153 |
| KYNU | kynureninase | 0.0230656 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0230242 |
| HKDC1 | hexokinase domain containing 1 | 0.0228585 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0228565 |
| LAMB3 | laminin, beta 3 | 0.0226174 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0225949 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0225615 |
| RNF24 | ring finger protein 24 | 0.0225047 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0223122 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0220859 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0219346 |
| RPS12 | ribosomal protein S12 | 0.0216548 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.263662 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130846 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0825329 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0681623 |
| RNF213 | ring finger protein 213 | -0.0680821 |
| LYZ | lysozyme | -0.0658005 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0639851 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0630435 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0590299 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0567468 |
| PERP | PERP, TP53 apoptosis effector | -0.050499 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0478568 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0473243 |
| TXNIP | thioredoxin interacting protein | -0.0472902 |
| SERINC5 | serine incorporator 5 | -0.0460877 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0459388 |
| HDAC4 | histone deacetylase 4 | -0.0451196 |
| PRELID2 | PRELI domain containing 2 | -0.0430011 |
| NDRG1 | N-myc downstream regulated 1 | -0.0429782 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0429758 |
| HLA-B | major histocompatibility complex, class I, B | -0.0423662 |
| CANX | calnexin | -0.0422418 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0416852 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0416726 |
| VCL | vinculin | -0.0402464 |
| HLA-C | major histocompatibility complex, class I, C | -0.0391509 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0384077 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0376752 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0357998 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0348976 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0344789 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.034322 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0342939 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.034107 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0338944 |
| FNIP1 | folliculin interacting protein 1 | -0.0331983 |
| AHI1 | Abelson helper integration site 1 | -0.0323965 |
| NPSR1 | neuropeptide S receptor 1 | -0.0323566 |
| RUNX1 | runt-related transcription factor 1 | -0.0311141 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0307665 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0302365 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0302054 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0300236 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0299847 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | -0.0298568 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0298373 |
| NCKAP5 | NCK-associated protein 5 | -0.029711 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0295273 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0293387 |
| H1-0 | H1.0 linker histone | -0.0288811 |
| TFRC | transferrin receptor | -0.0288448 |
| TNS4 | tensin 4 | -0.0284996 |
| HDLBP | high density lipoprotein binding protein | -0.028418 |
| TBPL1 | TBP-like 1 | -0.0282958 |
| DIAPH3 | diaphanous-related formin 3 | -0.0282001 |
| RAD51B | RAD51 paralog B | -0.0280699 |
| LNX2 | ligand of numb-protein X 2 | -0.0280403 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0278895 |
| AEBP2 | AE binding protein 2 | -0.027826 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0277784 |
| CDK6 | cyclin-dependent kinase 6 | -0.0275979 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0273015 |
| RNF43 | ring finger protein 43 | -0.026895 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0267613 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0265876 |
| XAF1 | XIAP associated factor 1 | -0.0265226 |
| PTMA | prothymosin, alpha | -0.0263309 |
| CENPF | centromere protein F, 350/400kDa | -0.0263139 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0258111 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0256142 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0255344 |
| LDHA | lactate dehydrogenase A | -0.0254041 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0251578 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0251463 |
| PATJ | PATJ crumbs cell polarity complex component | -0.025139 |
| OGA | O-GlcNAcase | -0.0248998 |
| TMEM62 | transmembrane protein 62 | -0.0248823 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0247766 |
| PKM | pyruvate kinase, muscle | -0.0247132 |
| PRKCA | protein kinase C, alpha | -0.024605 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0244493 |
| HLA-E | major histocompatibility complex, class I, E | -0.0243977 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0241204 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0239499 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0238365 |
| PLSCR2 | phospholipid scramblase 2 | -0.023832 |
| ENO1 | enolase 1, (alpha) | -0.0237792 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.023622 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0236143 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.023595 |
| CD46 | CD46 molecule, complement regulatory protein | -0.023584 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0232778 |
| HBS1L | HBS1-like translational GTPase | -0.0231717 |
| AHNAK | AHNAK nucleoprotein | -0.0230794 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0229879 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0229705 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0227426 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0227028 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0227 |
| ATXN1 | ataxin 1 | -0.0225963 |
