| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.191595 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.110875 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0609296 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.060526 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0460532 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0436544 |
| HLA-A | major histocompatibility complex, class I, A | 0.0415414 |
| STC1 | stanniocalcin 1 | 0.0353807 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0325398 |
| LOX | lysyl oxidase | 0.031004 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0303187 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0278453 |
| HMGA2 | high mobility group AT-hook 2 | 0.0276936 |
| KALRN | kalirin, RhoGEF kinase | 0.0275879 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0271208 |
| TLN1 | talin 1 | 0.0261048 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0251344 |
| GOLGA4 | golgin A4 | 0.0249626 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0249078 |
| C1S | complement component 1, s subcomponent | 0.0239707 |
| MYLK | myosin light chain kinase | 0.0237702 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0236291 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0221812 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0219104 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0217761 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0215872 |
| TPM3 | tropomyosin 3 | 0.0215384 |
| GPATCH2L | G patch domain containing 2-like | 0.0214693 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0214569 |
| GDF15 | growth differentiation factor 15 | 0.0211579 |
| IGF2 | insulin-like growth factor 2 | 0.0209155 |
| HLA-B | major histocompatibility complex, class I, B | 0.020862 |
| RPS6 | ribosomal protein S6 | 0.0206733 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0200569 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0199378 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0199352 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0195767 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.019517 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0194679 |
| SFTPA2 | surfactant protein A2 | 0.0190794 |
| SRP54 | signal recognition particle 54kDa | 0.019027 |
| COL12A1 | collagen, type XII, alpha 1 | 0.0189149 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0186808 |
| EGR1 | early growth response 1 | 0.0186118 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0180857 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0175929 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.017566 |
| GOLGB1 | golgin B1 | 0.0175066 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0174372 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0173458 |
| CALD1 | caldesmon 1 | 0.0171252 |
| CEP95 | centrosomal protein 95kDa | 0.0170396 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0168201 |
| NOPCHAP1 | NOP protein chaperone 1 | 0.0167683 |
| KCTD8 | potassium channel tetramerization domain containing 8 | 0.0164097 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.0162484 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0160079 |
| TMEM165 | transmembrane protein 165 | 0.0155446 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0153782 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0153346 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0151974 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0150535 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0150214 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0150079 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.014977 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.01496 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0149365 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0149022 |
| ZNF160 | zinc finger protein 160 | 0.0148725 |
| KIF26B | kinesin family member 26B | 0.0148711 |
| NXN | nucleoredoxin | 0.0148421 |
| B2M | beta-2-microglobulin | 0.0148137 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0146092 |
| SGMS1 | sphingomyelin synthase 1 | 0.0145821 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0143363 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0142707 |
| SECISBP2 | SECIS binding protein 2 | 0.014239 |
| VEGFA | vascular endothelial growth factor A | 0.0142181 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0141709 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.0141434 |
| MXI1 | MAX interactor 1, dimerization protein | 0.014136 |
| SPICE1 | spindle and centriole associated protein 1 | 0.0139576 |
| NUP58 | nucleoporin 58 | 0.0139366 |
| POLH | polymerase (DNA directed), eta | 0.0138879 |
| CA9 | carbonic anhydrase IX | 0.0138445 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0138056 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.0137453 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 0.0137374 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.0137011 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0136813 |
| HIP1 | huntingtin interacting protein 1 | 0.0136441 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0135946 |
| IKBIP | IKBKB interacting protein | 0.013565 |
| DNHD1 | dynein heavy chain domain 1 | 0.0134215 |
| PEG10 | paternally expressed 10 | 0.0133809 |
| MMP12 | matrix metallopeptidase 12 | 0.0133478 |
| RND3 | Rho family GTPase 3 | 0.013267 |
| KIAA1958 | KIAA1958 | 0.0132155 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0129959 |
| SLC37A3 | solute carrier family 37, member 3 | 0.0129351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.146251 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.145724 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.143654 |
| GRB10 | growth factor receptor-bound protein 10 | -0.13364 |
| NLGN1 | neuroligin 1 | -0.112401 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.112145 |
| FNDC3B | fibronectin type III domain containing 3B | -0.110574 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.110109 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.10455 |
| TMSB10 | thymosin beta 10 | -0.10285 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0970633 |
| KYNU | kynureninase | -0.0956842 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0945736 |
| NDRG1 | N-myc downstream regulated 1 | -0.0930756 |
| DST | dystonin | -0.0845158 |
| EGFR | epidermal growth factor receptor | -0.0756074 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0745511 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0717295 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0691547 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0689351 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0672701 |
| ATXN1 | ataxin 1 | -0.0670687 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0638158 |
| RUNX1 | runt-related transcription factor 1 | -0.0633164 |
| VCL | vinculin | -0.0587515 |
| MAP1B | microtubule-associated protein 1B | -0.0561941 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0552847 |
| PTK2 | protein tyrosine kinase 2 | -0.0549473 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.053014 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.052571 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0522641 |
| SEPTIN7 | septin 7 | -0.0517654 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0515172 |
| WWOX | WW domain containing oxidoreductase | -0.0508217 |
| ASPH | aspartate beta-hydroxylase | -0.0501346 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0494908 |
| PTMA | prothymosin, alpha | -0.0493534 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0491395 |
| RPLP1 | ribosomal protein, large, P1 | -0.0475863 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0473171 |
| USP34 | ubiquitin specific peptidase 34 | -0.0463861 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0453577 |
| TXNRD1 | thioredoxin reductase 1 | -0.0452323 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0445804 |
| PGK1 | phosphoglycerate kinase 1 | -0.0444932 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0440362 |
| NAV2 | neuron navigator 2 | -0.0437494 |
| SBF2 | SET binding factor 2 | -0.0432459 |
| TENM3 | teneurin transmembrane protein 3 | -0.0430274 |
| TPM4 | tropomyosin 4 | -0.0422862 |
| ANLN | anillin, actin binding protein | -0.0419321 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0418339 |
| FN1 | fibronectin 1 | -0.0415477 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0413864 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0412102 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0408522 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0407931 |
| GPC6 | glypican 6 | -0.0406099 |
| AUTS2 | autism susceptibility candidate 2 | -0.0401088 |
| CENPF | centromere protein F, 350/400kDa | -0.0400386 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0399407 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0394365 |
| SYT1 | synaptotagmin I | -0.0394219 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0392589 |
| RPL35A | ribosomal protein L35a | -0.0391911 |
| PALLD | palladin, cytoskeletal associated protein | -0.0387546 |
| GLIS3 | GLIS family zinc finger 3 | -0.038679 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0384859 |
| DIAPH3 | diaphanous-related formin 3 | -0.0382398 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0379908 |
| PRELID2 | PRELI domain containing 2 | -0.0378811 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0375748 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0372664 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0369166 |
| ANXA2 | annexin A2 | -0.0363903 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0361234 |
| RNF213 | ring finger protein 213 | -0.0357971 |
| STK17A | serine/threonine kinase 17a | -0.0356209 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.035177 |
| MT2A | metallothionein 2A | -0.0350576 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0350215 |
| AHNAK | AHNAK nucleoprotein | -0.0346393 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0341757 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0341752 |
| GLCCI1 | glucocorticoid induced 1 | -0.0340479 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0338464 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0335661 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.033053 |
| RPS19 | ribosomal protein S19 | -0.0330452 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0328455 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0322997 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0318978 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0313079 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0311612 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.031152 |
| LDHA | lactate dehydrogenase A | -0.0310278 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0309897 |
| SPAG9 | sperm associated antigen 9 | -0.03096 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0309473 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0309061 |
