| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.0768898 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0590366 |
| GOLGA4 | golgin A4 | 0.0471599 |
| RPS2 | ribosomal protein S2 | 0.0466458 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0385243 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0378366 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0374044 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0369344 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.034862 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0334281 |
| TPM3 | tropomyosin 3 | 0.0332016 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0304724 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0299455 |
| BRD2 | bromodomain containing 2 | 0.0291633 |
| TMF1 | TATA element modulatory factor 1 | 0.0286005 |
| RPL4 | ribosomal protein L4 | 0.0283657 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.027703 |
| BRD4 | bromodomain containing 4 | 0.0274171 |
| HLA-B | major histocompatibility complex, class I, B | 0.0273942 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0267832 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0264722 |
| NOP58 | NOP58 ribonucleoprotein | 0.0261022 |
| RPS12 | ribosomal protein S12 | 0.0256277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0249202 |
| EZR | ezrin | 0.0244264 |
| SRP54 | signal recognition particle 54kDa | 0.024392 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0236684 |
| SET | SET nuclear proto-oncogene | 0.0235116 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227073 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.02266 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0226351 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0212883 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.021099 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0203122 |
| KIF5B | kinesin family member 5B | 0.0203036 |
| TJP1 | tight junction protein 1 | 0.0199454 |
| RBM39 | RNA binding motif protein 39 | 0.0198825 |
| TUBA1B | tubulin, alpha 1b | 0.0194524 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0193758 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0193512 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0192428 |
| PCBP2 | poly(rC) binding protein 2 | 0.0191099 |
| CLEC16A | C-type lectin domain family 16, member A | 0.019063 |
| JUN | jun proto-oncogene | 0.0190068 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0189172 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0187898 |
| SLK | STE20-like kinase | 0.0181058 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0180167 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0178971 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0178822 |
| YBX3 | Y box binding protein 3 | 0.017623 |
| PAPOLA | poly(A) polymerase alpha | 0.0175827 |
| SUCO | SUN domain containing ossification factor | 0.017516 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.017487 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0173188 |
| RTN4 | reticulon 4 | 0.0171774 |
| TLN1 | talin 1 | 0.0171273 |
| ITSN2 | intersectin 2 | 0.0170558 |
| SON | SON DNA binding protein | 0.0169333 |
| SRPK2 | SRSF protein kinase 2 | 0.0168188 |
| MKI67 | marker of proliferation Ki-67 | 0.0167454 |
| PNN | pinin, desmosome associated protein | 0.0167346 |
| TXNRD1 | thioredoxin reductase 1 | 0.0166943 |
| RPL3 | ribosomal protein L3 | 0.0166628 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0166398 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0166111 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0165915 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0164989 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0163625 |
| CCDC186 | coiled-coil domain containing 186 | 0.0163585 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0163503 |
| GPR107 | G protein-coupled receptor 107 | 0.0162959 |
| YBX1 | Y box binding protein 1 | 0.0162067 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0157105 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0156153 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0155509 |
| IL6ST | interleukin 6 signal transducer | 0.0154869 |
| RBM25 | RNA binding motif protein 25 | 0.0154242 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0152886 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0152609 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.015162 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0151521 |
| CLU | clusterin | 0.0148955 |
| VIM | vimentin | 0.0148181 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0147569 |
| RRBP1 | ribosome binding protein 1 | 0.014707 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0146342 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0145679 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0142825 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0142432 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0141937 |
| FANCI | Fanconi anemia, complementation group I | 0.0141936 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0141667 |
| SMAD4 | SMAD family member 4 | 0.0140817 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0140618 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0139875 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0139849 |
| FTL | ferritin, light polypeptide | 0.0139109 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0138997 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0138636 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | -0.25612 |
| AHNAK | AHNAK nucleoprotein | -0.204971 |
| NDRG1 | N-myc downstream regulated 1 | -0.126966 |
| INTS6 | integrator complex subunit 6 | -0.122925 |
| PTMA | prothymosin, alpha | -0.09987 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.098567 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0950986 |
| SERINC5 | serine incorporator 5 | -0.0789091 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0778797 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0778281 |
| PRELID2 | PRELI domain containing 2 | -0.0754042 |
| TMSB10 | thymosin beta 10 | -0.0747847 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0723964 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0722742 |
| PKM | pyruvate kinase, muscle | -0.0648279 |
| KRT18 | keratin 18, type I | -0.0606715 |
| VCL | vinculin | -0.0597052 |
| RAD51B | RAD51 paralog B | -0.0586565 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0569036 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0556428 |
| TPM4 | tropomyosin 4 | -0.0545537 |
| MCL1 | myeloid cell leukemia 1 | -0.0534072 |
| FHIT | fragile histidine triad | -0.0530921 |
| CTBP2 | C-terminal binding protein 2 | -0.0529754 |
| LDHA | lactate dehydrogenase A | -0.0523749 |
| PGK1 | phosphoglycerate kinase 1 | -0.0491484 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0476867 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0454678 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0453993 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0453829 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0450394 |
| KRT8 | keratin 8, type II | -0.0424367 |
| KRT19 | keratin 19, type I | -0.0419736 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0417725 |
| ENO1 | enolase 1, (alpha) | -0.0417578 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0413093 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0402257 |
| CADPS | Ca++-dependent secretion activator | -0.0393251 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0388318 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0382152 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0365085 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0364424 |
| MSI2 | musashi RNA-binding protein 2 | -0.0359264 |
| RPS24 | ribosomal protein S24 | -0.0354333 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0348586 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0335432 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0332502 |
| RPL35A | ribosomal protein L35a | -0.0327448 |
| WWOX | WW domain containing oxidoreductase | -0.0325189 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0323907 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0323539 |
| AEBP2 | AE binding protein 2 | -0.0323329 |
| EXOC4 | exocyst complex component 4 | -0.0319273 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0317981 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0317227 |
| HOMER1 | homer scaffolding protein 1 | -0.0314793 |
| SNX14 | sorting nexin 14 | -0.0314261 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0313713 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0311781 |
| MEF2A | myocyte enhancer factor 2A | -0.0308809 |
| MYOF | myoferlin | -0.0308689 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0304917 |
| SBF2 | SET binding factor 2 | -0.0301238 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0298066 |
| CENPF | centromere protein F, 350/400kDa | -0.0297284 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0294253 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.029373 |
| NF1 | neurofibromin 1 | -0.0288167 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.028736 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0286162 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0284836 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0283568 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0283496 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0282974 |
| HMGA2 | high mobility group AT-hook 2 | -0.0274893 |
| LRRC23 | leucine rich repeat containing 23 | -0.0274071 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0272434 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.027024 |
| ASPH | aspartate beta-hydroxylase | -0.0267575 |
| FLNB | filamin B, beta | -0.0265642 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0263361 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0263254 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0261908 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0260833 |
| SECISBP2 | SECIS binding protein 2 | -0.0258674 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0257623 |
| ADD1 | adducin 1 (alpha) | -0.025731 |
| HOXB3 | homeobox B3 | -0.025568 |
| EPCAM | epithelial cell adhesion molecule | -0.0254341 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0252625 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0251241 |
| DENND1A | DENN/MADD domain containing 1A | -0.0249944 |
| DIAPH2 | diaphanous-related formin 2 | -0.0246832 |
| PTK2 | protein tyrosine kinase 2 | -0.0246292 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0241869 |
| FDPS | farnesyl diphosphate synthase | -0.024183 |
| PALD1 | phosphatase domain containing, paladin 1 | -0.0241122 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.023943 |
| MYO1E | myosin IE | -0.0236662 |
| CANX | calnexin | -0.023625 |
