| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.230402 |
| RPS6 | ribosomal protein S6 | 0.126415 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.123955 |
| LAMB3 | laminin, beta 3 | 0.118005 |
| GOLGA4 | golgin A4 | 0.105032 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0889438 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0812495 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0701171 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0691151 |
| GOLGB1 | golgin B1 | 0.0639558 |
| RPS2 | ribosomal protein S2 | 0.0609479 |
| EGR1 | early growth response 1 | 0.0597578 |
| LAMA4 | laminin, alpha 4 | 0.0593363 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0578699 |
| RUNX1 | runt-related transcription factor 1 | 0.0578185 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0575109 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0544341 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0539709 |
| MT2A | metallothionein 2A | 0.0518494 |
| DIAPH3 | diaphanous-related formin 3 | 0.0512647 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0507685 |
| FLNA | filamin A, alpha | 0.046771 |
| MKI67 | marker of proliferation Ki-67 | 0.0464963 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.045175 |
| VMP1 | vacuole membrane protein 1 | 0.0447894 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0423668 |
| RAD51B | RAD51 paralog B | 0.0423365 |
| LAMC2 | laminin, gamma 2 | 0.0421132 |
| CALR | calreticulin | 0.0418849 |
| RPL4 | ribosomal protein L4 | 0.041297 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0404148 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.040325 |
| EZR | ezrin | 0.0398657 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0393708 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0368607 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0360758 |
| SSH2 | slingshot protein phosphatase 2 | 0.0351409 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0345715 |
| ATF4 | activating transcription factor 4 | 0.0341314 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0339664 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.033346 |
| RACK1 | receptor for activated C kinase 1 | 0.0327378 |
| SEPTIN9 | septin 9 | 0.0325223 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0312701 |
| YBX1 | Y box binding protein 1 | 0.0311099 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0302312 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0302063 |
| NDRG1 | N-myc downstream regulated 1 | 0.0299869 |
| BRD2 | bromodomain containing 2 | 0.0294554 |
| TJP1 | tight junction protein 1 | 0.0293409 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0292133 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0291908 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0291168 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0288819 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0287895 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0286461 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0285362 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0282976 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0281292 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0279183 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.027433 |
| AXL | AXL receptor tyrosine kinase | 0.0274322 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0268337 |
| BPTF | bromodomain PHD finger transcription factor | 0.0264646 |
| CDK13 | cyclin-dependent kinase 13 | 0.0264517 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0258684 |
| ANXA1 | annexin A1 | 0.0258126 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0255209 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0254753 |
| CEP128 | centrosomal protein 128kDa | 0.0253266 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0252049 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0250207 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0249676 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0248276 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0247452 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.0246068 |
| TMF1 | TATA element modulatory factor 1 | 0.0245274 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0244566 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0241887 |
| BRCA1 | breast cancer 1, early onset | 0.0239361 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0237257 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.02357 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0233143 |
| BBX | bobby sox homolog (Drosophila) | 0.0229813 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0229252 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0225923 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0225241 |
| FNIP1 | folliculin interacting protein 1 | 0.0224647 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0224633 |
| STC2 | stanniocalcin 2 | 0.0224612 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0224579 |
| SEC24D | SEC24 family member D | 0.0224203 |
| CFAP44 | cilia and flagella associated protein 44 | 0.022311 |
| GNAS | GNAS complex locus | 0.0222549 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0221858 |
| CCDC88A | coiled-coil domain containing 88A | 0.0218198 |
| PRKCA | protein kinase C, alpha | 0.0217126 |
| RPS17 | ribosomal protein S17 | 0.0216248 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0215828 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.021536 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.190592 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.123866 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.108593 |
| ITGB8 | integrin, beta 8 | -0.104673 |
| PAX8 | paired box 8 | -0.100931 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0881975 |
| APP | amyloid beta (A4) precursor protein | -0.0878929 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0877717 |
| ASPH | aspartate beta-hydroxylase | -0.0865895 |
| LDHA | lactate dehydrogenase A | -0.0783053 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0659163 |
| KRT7 | keratin 7, type II | -0.0574123 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0557878 |
| POTEF | POTE ankyrin domain family, member F | -0.0536507 |
| PGK1 | phosphoglycerate kinase 1 | -0.0533453 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0517062 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0515309 |
| ZNF292 | zinc finger protein 292 | -0.0513461 |
| AHNAK | AHNAK nucleoprotein | -0.048777 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0476761 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0475974 |
| CCND1 | cyclin D1 | -0.045987 |
| TMSB4X | thymosin beta 4, X-linked | -0.0455453 |
| RPL23 | ribosomal protein L23 | -0.0454783 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0449497 |
| PRELID2 | PRELI domain containing 2 | -0.0445403 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0431977 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0431285 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0428439 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.04242 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0422989 |
| SBF2 | SET binding factor 2 | -0.0416267 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0409144 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0408845 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0408598 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0408337 |
| RPL19 | ribosomal protein L19 | -0.0404637 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0398581 |
| AFDN | afadin, adherens junction formation factor | -0.0393909 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0382644 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0371576 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0369546 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0368122 |
| OGA | O-GlcNAcase | -0.0366627 |
| RPS24 | ribosomal protein S24 | -0.0357454 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0347785 |
| B2M | beta-2-microglobulin | -0.0347537 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0345535 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0337277 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0335704 |
| ACTN4 | actinin, alpha 4 | -0.0334735 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0334441 |
| FTL | ferritin, light polypeptide | -0.0333259 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0332556 |
| TMSB10 | thymosin beta 10 | -0.033184 |
| NCKAP1 | NCK-associated protein 1 | -0.0330012 |
| RPS5 | ribosomal protein S5 | -0.0323915 |
| RASA2 | RAS p21 protein activator 2 | -0.0321699 |
| S100A6 | S100 calcium binding protein A6 | -0.0319415 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0316806 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0316418 |
| HMGA1 | high mobility group AT-hook 1 | -0.0310471 |
| KRT18 | keratin 18, type I | -0.0307977 |
| EREG | epiregulin | -0.0306353 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0306191 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0305948 |
| TJP2 | tight junction protein 2 | -0.0302317 |
| DPP4 | dipeptidyl-peptidase 4 | -0.0298229 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0297882 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0297256 |
| MACROD2 | MACRO domain containing 2 | -0.0295264 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0294653 |
| TRIM2 | tripartite motif containing 2 | -0.0293682 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.028577 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0284698 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0284346 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0280714 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0280595 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0279012 |
| RASA3 | RAS p21 protein activator 3 | -0.0273947 |
| MATR3 | matrin 3 | -0.0273742 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0273653 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0270739 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0267188 |
| RPL32 | ribosomal protein L32 | -0.0267028 |
| H3-3B | H3.3 histone B | -0.0265545 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0264837 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0264537 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0263873 |
| FIGN | fidgetin | -0.026264 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0261818 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0258129 |
| RLF | rearranged L-myc fusion | -0.0257291 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.0255125 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0254166 |
| SUMF1 | sulfatase modifying factor 1 | -0.0253387 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.025316 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0246915 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0245733 |
| RYK | receptor-like tyrosine kinase | -0.0243517 |
