| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.149063 |
| RPS6 | ribosomal protein S6 | 0.107958 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.076372 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0717725 |
| CALR | calreticulin | 0.0658126 |
| RPS2 | ribosomal protein S2 | 0.0644376 |
| HMGA2 | high mobility group AT-hook 2 | 0.0527781 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0492716 |
| YBX1 | Y box binding protein 1 | 0.0462639 |
| CANX | calnexin | 0.0459914 |
| GOLGA4 | golgin A4 | 0.0458856 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0431034 |
| COL3A1 | collagen, type III, alpha 1 | 0.0427406 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0425437 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0398583 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0391229 |
| DSTN | destrin (actin depolymerizing factor) | 0.0381574 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0377563 |
| COL1A1 | collagen, type I, alpha 1 | 0.0373829 |
| CDH13 | cadherin 13 | 0.036987 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0361695 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.035256 |
| TLN1 | talin 1 | 0.0338023 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0334987 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0328941 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0324185 |
| RPS8 | ribosomal protein S8 | 0.0322999 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0321416 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0320491 |
| MAP4 | microtubule-associated protein 4 | 0.0301578 |
| LOX | lysyl oxidase | 0.0300284 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0295867 |
| RND3 | Rho family GTPase 3 | 0.029083 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0289951 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0286862 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0285815 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0284337 |
| RPL26 | ribosomal protein L26 | 0.0278694 |
| TMF1 | TATA element modulatory factor 1 | 0.0262603 |
| RPL13A | ribosomal protein L13a | 0.0262401 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0257425 |
| TMSB4X | thymosin beta 4, X-linked | 0.0251653 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 0.0250976 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0249096 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0248709 |
| THY1 | Thy-1 cell surface antigen | 0.0247951 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0243565 |
| RPL4 | ribosomal protein L4 | 0.024102 |
| BRD4 | bromodomain containing 4 | 0.0231496 |
| KIF5B | kinesin family member 5B | 0.0228213 |
| CCDC80 | coiled-coil domain containing 80 | 0.0228193 |
| CLTC | clathrin, heavy chain (Hc) | 0.0226627 |
| CFB | complement factor B | 0.0225752 |
| MLEC | malectin | 0.0225695 |
| RPL5 | ribosomal protein L5 | 0.0224322 |
| RTN4 | reticulon 4 | 0.0222844 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0222038 |
| RSU1 | Ras suppressor protein 1 | 0.0221924 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0220767 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0219796 |
| RBM39 | RNA binding motif protein 39 | 0.0217085 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0215364 |
| TUBA1B | tubulin, alpha 1b | 0.0213151 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0212497 |
| FSTL1 | follistatin-like 1 | 0.0209802 |
| CDK13 | cyclin-dependent kinase 13 | 0.0207952 |
| HYOU1 | hypoxia up-regulated 1 | 0.0205517 |
| MLF1 | myeloid leukemia factor 1 | 0.0205034 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0203479 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.020323 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0200044 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0195284 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0194319 |
| TAOK1 | TAO kinase 1 | 0.0194251 |
| MTDH | metadherin | 0.0194048 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.019195 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0191318 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0190652 |
| VIRMA | vir like m6A methyltransferase associated | 0.0189508 |
| OSBP | oxysterol binding protein | 0.0189298 |
| MSN | moesin | 0.0188389 |
| TPR | translocated promoter region, nuclear basket protein | 0.0188249 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0187014 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0186181 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0186131 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0185751 |
| RPS12 | ribosomal protein S12 | 0.0185407 |
| CALD1 | caldesmon 1 | 0.0184385 |
| TPM3 | tropomyosin 3 | 0.0184118 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0183918 |
| USP36 | ubiquitin specific peptidase 36 | 0.0183372 |
| RPL36 | ribosomal protein L36 | 0.0183353 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0182037 |
| AXL | AXL receptor tyrosine kinase | 0.0181621 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0180686 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0179959 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0176957 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0175546 |
| RPS3 | ribosomal protein S3 | 0.0175255 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0173658 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.194963 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.156613 |
| VIM | vimentin | -0.119786 |
| COL6A3 | collagen, type VI, alpha 3 | -0.115776 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0897773 |
| IER3 | immediate early response 3 | -0.08531 |
| TMSB10 | thymosin beta 10 | -0.0831608 |
| MT2A | metallothionein 2A | -0.082922 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.080597 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0765832 |
| FBN1 | fibrillin 1 | -0.0696231 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0650762 |
| LDHA | lactate dehydrogenase A | -0.0617499 |
| FN1 | fibronectin 1 | -0.0596638 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0595459 |
| VEGFA | vascular endothelial growth factor A | -0.047212 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0470725 |
| B2M | beta-2-microglobulin | -0.0459678 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.044306 |
| ENO1 | enolase 1, (alpha) | -0.0441788 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0436143 |
| CD44 | CD44 molecule (Indian blood group) | -0.0428789 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0402824 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0399619 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0393362 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0392989 |
| MTSS1 | metastasis suppressor 1 | -0.0388079 |
| TMEM165 | transmembrane protein 165 | -0.038319 |
| RUNX1 | runt-related transcription factor 1 | -0.0368024 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0362367 |
| PRELID2 | PRELI domain containing 2 | -0.0360835 |
| SQSTM1 | sequestosome 1 | -0.0360149 |
| PTK2 | protein tyrosine kinase 2 | -0.0353861 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0352335 |
| KIAA1217 | KIAA1217 | -0.0351215 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0336289 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0332996 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0327977 |
| TPM4 | tropomyosin 4 | -0.0326602 |
| GLIS3 | GLIS family zinc finger 3 | -0.0310671 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0306526 |
| RPL35A | ribosomal protein L35a | -0.0304577 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.02937 |
| ACTG1 | actin gamma 1 | -0.0292136 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0284761 |
| OSMR | oncostatin M receptor | -0.0281501 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0272399 |
| IRF1 | interferon regulatory factor 1 | -0.0271594 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0271144 |
| IL6 | interleukin 6 | -0.0270615 |
| POTEF | POTE ankyrin domain family, member F | -0.0266694 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0263367 |
| SMAD3 | SMAD family member 3 | -0.026138 |
| PKM | pyruvate kinase, muscle | -0.0259899 |
| IL6ST | interleukin 6 signal transducer | -0.0257413 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0253836 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.024991 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0249234 |
| RNF213 | ring finger protein 213 | -0.0247529 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0245471 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0241504 |
| INTS6 | integrator complex subunit 6 | -0.0239296 |
| ARRDC3 | arrestin domain containing 3 | -0.0238224 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0237888 |
| EGFR | epidermal growth factor receptor | -0.0237029 |
| ADM | adrenomedullin | -0.0236502 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.023245 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0230356 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0230046 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0229287 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0224313 |
| BNC2 | basonuclin 2 | -0.0224255 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0222276 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0219641 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0217117 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0212446 |
| FRMD4A | FERM domain containing 4A | -0.021133 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0210037 |
| ITGAV | integrin, alpha V | -0.0209159 |
| PGK1 | phosphoglycerate kinase 1 | -0.0206675 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0206132 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0205713 |
| S100A6 | S100 calcium binding protein A6 | -0.0205598 |
| GLRX | glutaredoxin (thioltransferase) | -0.0204974 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0204781 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0204666 |
| PRKCE | protein kinase C, epsilon | -0.0204535 |
| H3-3B | H3.3 histone B | -0.0203873 |
| TAGLN2 | transgelin 2 | -0.0203839 |
| RPS24 | ribosomal protein S24 | -0.0198787 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0197659 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0197217 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0196549 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0196258 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0196109 |
| CLMP | CXADR-like membrane protein | -0.0195015 |
| PXDN | peroxidasin | -0.0194912 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0194323 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0192436 |
| HMGA1 | high mobility group AT-hook 1 | -0.0191494 |
