| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BCL2L1 | BCL2-like 1 | 0.0540878 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0496329 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0482006 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0459423 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.044082 |
| RPS2 | ribosomal protein S2 | 0.0350074 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0328878 |
| MKI67 | marker of proliferation Ki-67 | 0.0314023 |
| SMYD3 | SET and MYND domain containing 3 | 0.0302005 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0301585 |
| NTN4 | netrin 4 | 0.0291864 |
| LATS2 | large tumor suppressor kinase 2 | 0.0288418 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0282665 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0281413 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0270077 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0265949 |
| RPS6 | ribosomal protein S6 | 0.0260531 |
| RPS12 | ribosomal protein S12 | 0.0259322 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0252635 |
| RPL4 | ribosomal protein L4 | 0.0248131 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0243687 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0240374 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.023764 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.0235901 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0230814 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0228124 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0226906 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0219796 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.021265 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0207919 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0206267 |
| SHROOM3 | shroom family member 3 | 0.0201849 |
| RND3 | Rho family GTPase 3 | 0.019717 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0196435 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0194532 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0194165 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.019317 |
| WWOX | WW domain containing oxidoreductase | 0.0189013 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0186955 |
| TUBA1B | tubulin, alpha 1b | 0.0186705 |
| PPL | periplakin | 0.0184267 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0183847 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0180842 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0175961 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0175246 |
| SEPTIN9 | septin 9 | 0.0172031 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0166746 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0165441 |
| SGMS2 | sphingomyelin synthase 2 | 0.0164197 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | 0.0162326 |
| GPHN | gephyrin | 0.0161759 |
| LMO7 | LIM domain 7 | 0.0160504 |
| HMGB2 | high mobility group box 2 | 0.01596 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0159148 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0158599 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0157753 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0155483 |
| WWC1 | WW and C2 domain containing 1 | 0.0150561 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0150293 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0149573 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0145113 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0144868 |
| CENPP | centromere protein P | 0.0144865 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0144291 |
| TGFA | transforming growth factor, alpha | 0.0142061 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.014147 |
| NXN | nucleoredoxin | 0.0138905 |
| TEX14 | testis expressed 14 | 0.0137759 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0136173 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0135834 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0135543 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0133443 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0133179 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0133017 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0131085 |
| ANXA11 | annexin A11 | 0.013066 |
| RIGI | RNA sensor RIG-I | 0.0130478 |
| GOLM1 | golgi membrane protein 1 | 0.0130147 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0129699 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0129322 |
| ETV6 | ets variant 6 | 0.012683 |
| MYO1D | myosin ID | 0.0125959 |
| TPM3 | tropomyosin 3 | 0.012449 |
| CCNYL1 | cyclin Y-like 1 | 0.0124411 |
| BRCA2 | breast cancer 2, early onset | 0.0123368 |
| AOPEP | aminopeptidase O (putative) | 0.0123039 |
| TPI1 | triosephosphate isomerase 1 | 0.0121092 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0120671 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0120225 |
| IRF3 | interferon regulatory factor 3 | 0.0120138 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0119112 |
| TMEM117 | transmembrane protein 117 | 0.0117862 |
| EXOC6B | exocyst complex component 6B | 0.0117713 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0115713 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0115692 |
| HELLS | helicase, lymphoid-specific | 0.0115507 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0115069 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0113811 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0113591 |
| CLIC5 | chloride intracellular channel 5 | 0.0112429 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.2199 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.148555 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.123982 |
| FTL | ferritin, light polypeptide | -0.117288 |
| FRY | furry homolog (Drosophila) | -0.109824 |
| LDHA | lactate dehydrogenase A | -0.108948 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0953417 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0930336 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0868854 |
| LYZ | lysozyme | -0.0854431 |
| ANXA2 | annexin A2 | -0.0847968 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0836621 |
| TXNRD1 | thioredoxin reductase 1 | -0.0822124 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0681151 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0671694 |
| ATXN1 | ataxin 1 | -0.0667578 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0664599 |
| PGK1 | phosphoglycerate kinase 1 | -0.0652926 |
| TMEM65 | transmembrane protein 65 | -0.063416 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0625825 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0615387 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0585644 |
| GOLGA4 | golgin A4 | -0.0582326 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0580678 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0577682 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0568809 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0568074 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0565873 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0563032 |
| AGR2 | anterior gradient 2 | -0.0554947 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0548412 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0536488 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0535782 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0531198 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0529008 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0523867 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0520358 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0510661 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0495571 |
| CANX | calnexin | -0.0488728 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0487191 |
| TMEM123 | transmembrane protein 123 | -0.0470378 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0468916 |
| SQSTM1 | sequestosome 1 | -0.0464149 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0461206 |
| HM13 | histocompatibility (minor) 13 | -0.0455384 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0450216 |
| WASF2 | WAS protein family, member 2 | -0.0449393 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0443597 |
| DIAPH2 | diaphanous-related formin 2 | -0.0441537 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0439441 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0436442 |
| ARF4 | ADP-ribosylation factor 4 | -0.043429 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0418725 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0414796 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0403154 |
| TMSB10 | thymosin beta 10 | -0.0396649 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0395987 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0395857 |
| S100A6 | S100 calcium binding protein A6 | -0.0391782 |
| CCNY | cyclin Y | -0.0390738 |
| MORF4L2 | mortality factor 4 like 2 | -0.0387182 |
| ENO1 | enolase 1, (alpha) | -0.038689 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0384895 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0383379 |
| ZNF292 | zinc finger protein 292 | -0.0378743 |
| CD2AP | CD2-associated protein | -0.0377442 |
| TES | testin LIM domain protein | -0.03768 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0375602 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0375192 |
| SBF2 | SET binding factor 2 | -0.0372947 |
| HDLBP | high density lipoprotein binding protein | -0.037264 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0371248 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0370808 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0370482 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0366056 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0364286 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0363062 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0360425 |
| POTEF | POTE ankyrin domain family, member F | -0.0355095 |
| USP34 | ubiquitin specific peptidase 34 | -0.0350539 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0350328 |
| COG5 | component of oligomeric golgi complex 5 | -0.0350325 |
| NF1 | neurofibromin 1 | -0.0347554 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0345776 |
| FAM13A | family with sequence similarity 13, member A | -0.0345165 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0341724 |
| DGKH | diacylglycerol kinase, eta | -0.0340309 |
| TRAM1 | translocation associated membrane protein 1 | -0.0339634 |
| HYOU1 | hypoxia up-regulated 1 | -0.0338808 |
| USP3 | ubiquitin specific peptidase 3 | -0.0335219 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0334112 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0333761 |
| PKM | pyruvate kinase, muscle | -0.0333181 |
| WDR45B | WD repeat domain 45B | -0.033302 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0332495 |
| PTMA | prothymosin, alpha | -0.0332123 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0331695 |
| XPOT | exportin, tRNA | -0.0331645 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0331406 |
