| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.115616 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0452308 |
| MT2A | metallothionein 2A | 0.0350339 |
| TNS1 | tensin 1 | 0.0335262 |
| RPS6 | ribosomal protein S6 | 0.0334655 |
| SVIL | supervillin | 0.0330035 |
| PCBP2 | poly(rC) binding protein 2 | 0.0262871 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0260739 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0241859 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0234433 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0225978 |
| NDRG1 | N-myc downstream regulated 1 | 0.0216153 |
| RPS2 | ribosomal protein S2 | 0.0205568 |
| CRY1 | cryptochrome circadian clock 1 | 0.0205216 |
| MYADM | myeloid-associated differentiation marker | 0.0186781 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0168985 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0168373 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0165096 |
| FAM13A | family with sequence similarity 13, member A | 0.0153648 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0150541 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.014167 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0141345 |
| EZR | ezrin | 0.0134172 |
| FBXO42 | F-box protein 42 | 0.013267 |
| NUP58 | nucleoporin 58 | 0.0128943 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | 0.0126785 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0125843 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0125045 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.012468 |
| PER2 | period circadian clock 2 | 0.0123314 |
| VIM | vimentin | 0.0121514 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0119064 |
| GOLGA4 | golgin A4 | 0.0118032 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0117515 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0116303 |
| RPL4 | ribosomal protein L4 | 0.0115214 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0112179 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0112025 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0111343 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0110147 |
| PNN | pinin, desmosome associated protein | 0.0108128 |
| RUNX1 | runt-related transcription factor 1 | 0.0107839 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0107163 |
| CCNL1 | cyclin L1 | 0.0106299 |
| ATF3 | activating transcription factor 3 | 0.0106063 |
| DHFR | dihydrofolate reductase | 0.0103417 |
| TMF1 | TATA element modulatory factor 1 | 0.0098752 |
| RPL3 | ribosomal protein L3 | 0.00982287 |
| CCN2 | cellular communication network factor 2 | 0.00982133 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00972093 |
| NGLY1 | N-glycanase 1 | 0.00960974 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.00953449 |
| STC2 | stanniocalcin 2 | 0.00952424 |
| BRD2 | bromodomain containing 2 | 0.00946836 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.00945152 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0094097 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00939325 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00934599 |
| ELL | elongation factor RNA polymerase II | 0.00933655 |
| TXNRD1 | thioredoxin reductase 1 | 0.00932811 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00931707 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00930988 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.00925635 |
| RPL5 | ribosomal protein L5 | 0.00919348 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00915989 |
| RNF24 | ring finger protein 24 | 0.0090991 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00904413 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0089855 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0089737 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.00895576 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00876544 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.00865864 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00865142 |
| CEP290 | centrosomal protein 290kDa | 0.00865047 |
| BRD4 | bromodomain containing 4 | 0.0086266 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.00861528 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00861183 |
| RASA2 | RAS p21 protein activator 2 | 0.00857537 |
| STK35 | serine/threonine kinase 35 | 0.00848009 |
| KALRN | kalirin, RhoGEF kinase | 0.0084576 |
| MXRA7 | matrix-remodelling associated 7 | 0.00835069 |
| EGFR | epidermal growth factor receptor | 0.00827667 |
| CD44 | CD44 molecule (Indian blood group) | 0.00823409 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.00818723 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00817776 |
| SF1 | splicing factor 1 | 0.00813757 |
| IL4R | interleukin 4 receptor | 0.0081334 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 0.00792851 |
| CCND1 | cyclin D1 | 0.00792532 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.00791378 |
| TPM3 | tropomyosin 3 | 0.00788525 |
| EFNA5 | ephrin-A5 | 0.00787018 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00779733 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.00779678 |
| AAK1 | AP2 associated kinase 1 | 0.00776561 |
| BSDC1 | BSD domain containing 1 | 0.00776275 |
| PML | promyelocytic leukemia | 0.00776126 |
| SET | SET nuclear proto-oncogene | 0.00772643 |
| ANGPTL2 | angiopoietin-like 2 | 0.00762649 |
| MSN | moesin | 0.00761758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.192127 |
| FN1 | fibronectin 1 | -0.189124 |
| GPC3 | glypican 3 | -0.13279 |
| FNDC3B | fibronectin type III domain containing 3B | -0.13153 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.110731 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0996612 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0996022 |
| GPC6 | glypican 6 | -0.0985657 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0937645 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0930535 |
| PEG3 | paternally expressed 3 | -0.0919375 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0874786 |
| NPAS2 | neuronal PAS domain protein 2 | -0.087154 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0841245 |
| EHBP1 | EH domain binding protein 1 | -0.0840634 |
| C3 | complement component 3 | -0.0799371 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0777612 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0748534 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0720612 |
| ATXN1 | ataxin 1 | -0.0699764 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0682338 |
| CP | ceruloplasmin (ferroxidase) | -0.0678317 |
| AHSG | alpha-2-HS-glycoprotein | -0.0656231 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0642241 |
| RPS24 | ribosomal protein S24 | -0.0633055 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0626833 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0623915 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0622858 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0619593 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0613709 |
| RNF213 | ring finger protein 213 | -0.0600693 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0599288 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0583158 |
| ENO1 | enolase 1, (alpha) | -0.0577002 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0573564 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0572763 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0565195 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0562866 |
| ASPH | aspartate beta-hydroxylase | -0.0557492 |
| DST | dystonin | -0.0538992 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0538682 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0537805 |
| SDC4 | syndecan 4 | -0.051571 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0514848 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0512636 |
| TMEM123 | transmembrane protein 123 | -0.0504425 |
| PHF3 | PHD finger protein 3 | -0.0492673 |
| FMNL2 | formin-like 2 | -0.049215 |
| INTS6 | integrator complex subunit 6 | -0.0487299 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0481615 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0474049 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0460293 |
| VCL | vinculin | -0.0454447 |
| TRIM26 | tripartite motif containing 26 | -0.0452988 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0451355 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0451174 |
| TF | transferrin | -0.0445113 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0440311 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.042459 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0422937 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0419565 |
| GNAS | GNAS complex locus | -0.0413914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0411298 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0410156 |
| MSI2 | musashi RNA-binding protein 2 | -0.0403078 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0395434 |
| RPL23 | ribosomal protein L23 | -0.0393114 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0391719 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0390325 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0390014 |
| LDHA | lactate dehydrogenase A | -0.0382257 |
| GK | glycerol kinase | -0.0382031 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0380712 |
| PLIN2 | perilipin 2 | -0.0374013 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0372505 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0372136 |
| PTCHD4 | patched domain containing 4 | -0.0364616 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0359172 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0354654 |
| IGF2 | insulin-like growth factor 2 | -0.0353021 |
| KIF21A | kinesin family member 21A | -0.0346528 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0345579 |
| TFRC | transferrin receptor | -0.0345126 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0339489 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.033835 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0338138 |
| APOA2 | apolipoprotein A-II | -0.0335238 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0333548 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0323749 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0322971 |
| A2M | alpha-2-macroglobulin | -0.0321083 |
| CTSB | cathepsin B | -0.032054 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0311966 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0310913 |
| RDX | radixin | -0.0309082 |
| APOE | apolipoprotein E | -0.030711 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0306912 |
| FTL | ferritin, light polypeptide | -0.0303267 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0302259 |
| PRKCA | protein kinase C, alpha | -0.0302041 |
