| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.103072 |
| MT2A | metallothionein 2A | 0.099116 |
| RPS6 | ribosomal protein S6 | 0.0926272 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0897737 |
| STC1 | stanniocalcin 1 | 0.0788943 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0767264 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0707706 |
| TGM2 | transglutaminase 2 | 0.0699492 |
| PODXL | podocalyxin-like | 0.0682872 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0533324 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0510455 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0492181 |
| RPS8 | ribosomal protein S8 | 0.0476339 |
| MT1E | metallothionein 1E | 0.0453795 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0383335 |
| RAI14 | retinoic acid induced 14 | 0.0377943 |
| RPS12 | ribosomal protein S12 | 0.0376997 |
| RPS2 | ribosomal protein S2 | 0.0373244 |
| EZR | ezrin | 0.0349651 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0344252 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0342822 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0331486 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0316681 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0316657 |
| ANXA1 | annexin A1 | 0.0304416 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0301134 |
| BARX2 | BARX homeobox 2 | 0.0300453 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0300436 |
| FNDC3B | fibronectin type III domain containing 3B | 0.029982 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0298634 |
| TPM3 | tropomyosin 3 | 0.0298455 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0297871 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0297299 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0295919 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0295267 |
| DOK5 | docking protein 5 | 0.0294271 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0291693 |
| SLK | STE20-like kinase | 0.0287315 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0280341 |
| LAMA5 | laminin, alpha 5 | 0.0276411 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0275118 |
| PCBP2 | poly(rC) binding protein 2 | 0.0268097 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0265264 |
| B2M | beta-2-microglobulin | 0.0264643 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0263885 |
| FAM107B | family with sequence similarity 107, member B | 0.0259548 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0257916 |
| RPL37A | ribosomal protein L37a | 0.0256739 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0256061 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.025426 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0253604 |
| RPS3 | ribosomal protein S3 | 0.0250493 |
| VIM | vimentin | 0.0250202 |
| FTL | ferritin, light polypeptide | 0.0247651 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0243945 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0243264 |
| UBC | ubiquitin C | 0.0239371 |
| ANGPTL4 | angiopoietin-like 4 | 0.0238685 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0237136 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0235415 |
| ATF4 | activating transcription factor 4 | 0.0233609 |
| VEGFA | vascular endothelial growth factor A | 0.0228691 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0226991 |
| CALB1 | calbindin 1, 28kDa | 0.0226804 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0225457 |
| HLA-B | major histocompatibility complex, class I, B | 0.0225324 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0223512 |
| MXRA5 | matrix-remodelling associated 5 | 0.0223389 |
| DSPP | dentin sialophosphoprotein | 0.0223207 |
| RPL21 | ribosomal protein L21 | 0.0219221 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0217512 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0215871 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.021531 |
| NAV2 | neuron navigator 2 | 0.0214156 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0213843 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.021007 |
| MKI67 | marker of proliferation Ki-67 | 0.0209326 |
| RACK1 | receptor for activated C kinase 1 | 0.0209073 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0205779 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0203209 |
| RPL5 | ribosomal protein L5 | 0.0201964 |
| IRS2 | insulin receptor substrate 2 | 0.020142 |
| CDCP1 | CUB domain containing protein 1 | 0.0200926 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0200648 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0200348 |
| RPS17 | ribosomal protein S17 | 0.0198556 |
| DUSP5 | dual specificity phosphatase 5 | 0.0197774 |
| RPL28 | ribosomal protein L28 | 0.0196671 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0196466 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0196412 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0193519 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0188046 |
| TXNIP | thioredoxin interacting protein | 0.018765 |
| RND3 | Rho family GTPase 3 | 0.0185897 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.018559 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0184736 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0182757 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.018271 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0182542 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0181909 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.263009 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.185794 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.12392 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.117872 |
| FOXO1 | forkhead box O1 | -0.114088 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0914274 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0888116 |
| VCL | vinculin | -0.0886307 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0838072 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0831626 |
| AHNAK | AHNAK nucleoprotein | -0.0822518 |
| ITGA6 | integrin, alpha 6 | -0.0768799 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0753786 |
| NRG1 | neuregulin 1 | -0.0752968 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0718573 |
| FOXP1 | forkhead box P1 | -0.0696532 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0691513 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0678745 |
| NEK7 | NIMA-related kinase 7 | -0.0650597 |
| NDRG1 | N-myc downstream regulated 1 | -0.0645606 |
| ANXA2 | annexin A2 | -0.0628725 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0622809 |
| PALLD | palladin, cytoskeletal associated protein | -0.0604967 |
| BCL2L1 | BCL2-like 1 | -0.0592258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0585865 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0573734 |
| PGK1 | phosphoglycerate kinase 1 | -0.0568009 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0565403 |
| FN1 | fibronectin 1 | -0.0549861 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0541202 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0532504 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0524635 |
| OSMR | oncostatin M receptor | -0.0521562 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0514944 |
| PRELID2 | PRELI domain containing 2 | -0.0514011 |
| CD44 | CD44 molecule (Indian blood group) | -0.0513922 |
| INTS6 | integrator complex subunit 6 | -0.0509522 |
| CANX | calnexin | -0.050006 |
| PLEC | plectin | -0.0478914 |
| CUL4B | cullin 4B | -0.0478559 |
| MYOF | myoferlin | -0.0470056 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0457059 |
| EMP1 | epithelial membrane protein 1 | -0.0456137 |
| MYO10 | myosin X | -0.045235 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0442164 |
| RAB10 | RAB10, member RAS oncogene family | -0.0441862 |
| CAPRIN2 | caprin family member 2 | -0.0434209 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.042163 |
| AOPEP | aminopeptidase O (putative) | -0.0419513 |
| SULF1 | sulfatase 1 | -0.0414189 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0411733 |
| BLCAP | bladder cancer associated protein | -0.0405682 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0402352 |
| LDHA | lactate dehydrogenase A | -0.0401123 |
| MORF4L2 | mortality factor 4 like 2 | -0.0398116 |
| IGF2 | insulin-like growth factor 2 | -0.0397129 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0396505 |
| TMSB4X | thymosin beta 4, X-linked | -0.0394739 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0392769 |
| ACTN4 | actinin, alpha 4 | -0.0392538 |
| TMSB10 | thymosin beta 10 | -0.0389004 |
| ANLN | anillin, actin binding protein | -0.0385656 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0381815 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0381144 |
| C4BPB | complement component 4 binding protein, beta | -0.0378212 |
| POTEF | POTE ankyrin domain family, member F | -0.0376273 |
| HDLBP | high density lipoprotein binding protein | -0.0376207 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0372352 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0365419 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0364856 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0362593 |
| COPA | coatomer protein complex, subunit alpha | -0.0358394 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0356178 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0355977 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0354702 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0350963 |
| CAVIN1 | caveolae associated protein 1 | -0.0343942 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0341985 |
| RASAL2 | RAS protein activator like 2 | -0.0338338 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.033751 |
| SBF2 | SET binding factor 2 | -0.033716 |
| LUZP1 | leucine zipper protein 1 | -0.0337013 |
| DGKH | diacylglycerol kinase, eta | -0.0336324 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0333568 |
| LMNA | lamin A/C | -0.0333069 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0332517 |
| DOCK9 | dedicator of cytokinesis 9 | -0.033206 |
| RIGI | RNA sensor RIG-I | -0.0328897 |
| GNAS | GNAS complex locus | -0.0325897 |
| CLU | clusterin | -0.0322805 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0321482 |
| ZNF217 | zinc finger protein 217 | -0.0321277 |
| SETX | senataxin | -0.0320059 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0315691 |
| BSG | basigin (Ok blood group) | -0.0315424 |
| RBM39 | RNA binding motif protein 39 | -0.0312725 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0310036 |
| KRT6A | keratin 6A, type II | -0.030782 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.030703 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0306477 |
