| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.108433 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0836148 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0772163 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0686615 |
| ASPH | aspartate beta-hydroxylase | 0.0652146 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0603352 |
| TLN1 | talin 1 | 0.0565797 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0553803 |
| TPM3 | tropomyosin 3 | 0.0536721 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0483541 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0468982 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0457731 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0436936 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0436369 |
| RND3 | Rho family GTPase 3 | 0.0431873 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0410357 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0400131 |
| DST | dystonin | 0.0394118 |
| YBX1 | Y box binding protein 1 | 0.0372577 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0372024 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0354539 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0346819 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0340686 |
| RPS2 | ribosomal protein S2 | 0.0339405 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.032925 |
| DIAPH3 | diaphanous-related formin 3 | 0.0324085 |
| MKI67 | marker of proliferation Ki-67 | 0.0323752 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0321854 |
| RIGI | RNA sensor RIG-I | 0.0320549 |
| CAVIN1 | caveolae associated protein 1 | 0.0318132 |
| NAV2 | neuron navigator 2 | 0.0316515 |
| CD44 | CD44 molecule (Indian blood group) | 0.0316489 |
| RPS8 | ribosomal protein S8 | 0.0310986 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0307885 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0307198 |
| MAP1B | microtubule-associated protein 1B | 0.0305531 |
| RUNX1 | runt-related transcription factor 1 | 0.0302931 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0302606 |
| TPX2 | TPX2, microtubule-associated | 0.0299536 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0294975 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.029203 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0291925 |
| DTNA | dystrobrevin, alpha | 0.0289972 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0282168 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0281084 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0279671 |
| LMNA | lamin A/C | 0.0278318 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.027797 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0277502 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0268675 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0267657 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0265542 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0260012 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.025958 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0256296 |
| ANXA1 | annexin A1 | 0.025465 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.025209 |
| YBX3 | Y box binding protein 3 | 0.0250771 |
| ENAH | enabled homolog (Drosophila) | 0.0249309 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0247604 |
| COL3A1 | collagen, type III, alpha 1 | 0.0247599 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0247594 |
| FUS | FUS RNA binding protein | 0.0246667 |
| CREBBP | CREB binding protein | 0.0246172 |
| SET | SET nuclear proto-oncogene | 0.024612 |
| TLE4 | transducin-like enhancer of split 4 | 0.024569 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0243855 |
| MSN | moesin | 0.0243841 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0242636 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0241504 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0238468 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0236822 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0236387 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0235898 |
| CANX | calnexin | 0.0235475 |
| BPTF | bromodomain PHD finger transcription factor | 0.0231801 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.022999 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0229626 |
| EPHA4 | EPH receptor A4 | 0.0226469 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0224392 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0223338 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0223135 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0222676 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0221858 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0220838 |
| RNF213 | ring finger protein 213 | 0.0220208 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0216396 |
| FAM107B | family with sequence similarity 107, member B | 0.0215854 |
| AHNAK | AHNAK nucleoprotein | 0.0215251 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0214857 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0213884 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0212927 |
| FLNA | filamin A, alpha | 0.0212017 |
| FOXC1 | forkhead box C1 | 0.0210998 |
| GNAS | GNAS complex locus | 0.0209388 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0205887 |
| RPS12 | ribosomal protein S12 | 0.02036 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0202604 |
| PCDH17 | protocadherin 17 | 0.020076 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0200043 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.310825 |
| FTL | ferritin, light polypeptide | -0.112459 |
| HLA-B | major histocompatibility complex, class I, B | -0.104326 |
| MT2A | metallothionein 2A | -0.0699686 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0650011 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0630534 |
| LDHA | lactate dehydrogenase A | -0.0628471 |
| NDRG1 | N-myc downstream regulated 1 | -0.0529461 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.052688 |
| CCNL1 | cyclin L1 | -0.0516457 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0513412 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0470597 |
| ADM | adrenomedullin | -0.0470203 |
| FN1 | fibronectin 1 | -0.0454698 |
| MT1X | metallothionein 1X | -0.0449922 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0419007 |
| B2M | beta-2-microglobulin | -0.0408321 |
| FOSL1 | FOS-like antigen 1 | -0.0375428 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0364535 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0362193 |
| ATP13A3 | ATPase type 13A3 | -0.0329799 |
| SQSTM1 | sequestosome 1 | -0.0314234 |
| PGK1 | phosphoglycerate kinase 1 | -0.0308016 |
| ENO1 | enolase 1, (alpha) | -0.0300684 |
| ANKRD10 | ankyrin repeat domain 10 | -0.029235 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0291325 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0291218 |
| ARF4 | ADP-ribosylation factor 4 | -0.0280744 |
| NUP58 | nucleoporin 58 | -0.0278925 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0277015 |
| KRT7 | keratin 7, type II | -0.027628 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0271654 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0271505 |
| PLIN2 | perilipin 2 | -0.0270335 |
| UBC | ubiquitin C | -0.025641 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0248359 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0244592 |
| TSC22D2 | TSC22 domain family, member 2 | -0.024291 |
| TXNRD1 | thioredoxin reductase 1 | -0.0234111 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0231774 |
| PTX3 | pentraxin 3, long | -0.0231453 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.02285 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0222891 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.022243 |
| SULF1 | sulfatase 1 | -0.0222389 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0222144 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0217464 |
| HLA-A | major histocompatibility complex, class I, A | -0.0213596 |
| POTEF | POTE ankyrin domain family, member F | -0.0210607 |
| TMSB10 | thymosin beta 10 | -0.0210589 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0210579 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0209299 |
| CTSD | cathepsin D | -0.0208515 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.020825 |
| TPM1 | tropomyosin 1 (alpha) | -0.0207453 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0203984 |
| UPP1 | uridine phosphorylase 1 | -0.0203178 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0201463 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0198073 |
| NXN | nucleoredoxin | -0.0198022 |
| TFG | TRK-fused gene | -0.0196882 |
| DEK | DEK proto-oncogene | -0.0193241 |
| SPAG9 | sperm associated antigen 9 | -0.0189331 |
| TMEM41B | transmembrane protein 41B | -0.0186796 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0185744 |
| SBF2 | SET binding factor 2 | -0.0184713 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.018276 |
| XPO6 | exportin 6 | -0.0178009 |
| H1-0 | H1.0 linker histone | -0.017792 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0177243 |
| S100A6 | S100 calcium binding protein A6 | -0.017672 |
| RBL1 | retinoblastoma-like 1 | -0.0175733 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0175213 |
| POSTN | periostin, osteoblast specific factor | -0.0174593 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0174241 |
| RHEB | Ras homolog enriched in brain | -0.0173886 |
| ZNF292 | zinc finger protein 292 | -0.0170888 |
| BARD1 | BRCA1 associated RING domain 1 | -0.0167858 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0167199 |
| PFN1 | profilin 1 | -0.016473 |
| GRAMD2B | GRAM domain containing 2B | -0.0163317 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0160144 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -0.0159259 |
| CENPP | centromere protein P | -0.0158307 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0158066 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0156751 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0155839 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.015517 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0155084 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0154861 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.0150344 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0148494 |
| GMPS | guanine monphosphate synthase | -0.014784 |
| RLIM | ring finger protein, LIM domain interacting | -0.0145853 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0145065 |
| VGLL3 | vestigial-like family member 3 | -0.0144832 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0143198 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0141756 |
| TAGLN2 | transgelin 2 | -0.0139674 |
| INSIG2 | insulin induced gene 2 | -0.0139567 |
