| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.123473 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0844038 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0796782 |
| RPS2 | ribosomal protein S2 | 0.0710955 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0670244 |
| RPS12 | ribosomal protein S12 | 0.065077 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0614259 |
| PTCHD4 | patched domain containing 4 | 0.0544149 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0489539 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0475603 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0470579 |
| FLNA | filamin A, alpha | 0.04271 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0419874 |
| HDAC9 | histone deacetylase 9 | 0.0407626 |
| RPL4 | ribosomal protein L4 | 0.0406038 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0398757 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0386 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0364885 |
| TLN1 | talin 1 | 0.0351842 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0337828 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.03363 |
| DTNA | dystrobrevin, alpha | 0.0331297 |
| HMGA2 | high mobility group AT-hook 2 | 0.0327885 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0300613 |
| EGR1 | early growth response 1 | 0.0294583 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0284922 |
| TPM3 | tropomyosin 3 | 0.0266363 |
| EFNA5 | ephrin-A5 | 0.0248456 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0241851 |
| INTS6 | integrator complex subunit 6 | 0.0241739 |
| STPG4 | sperm-tail PG-rich repeat containing 4 | 0.0238419 |
| NAV3 | neuron navigator 3 | 0.0237156 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0229941 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0229414 |
| ATF3 | activating transcription factor 3 | 0.0222799 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0222717 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0219131 |
| EPHA4 | EPH receptor A4 | 0.0209802 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0209119 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0208324 |
| RACK1 | receptor for activated C kinase 1 | 0.0195956 |
| TEX14 | testis expressed 14 | 0.0195762 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0194181 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0192274 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.019194 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0187747 |
| FMN1 | formin 1 | 0.0187262 |
| SECISBP2 | SECIS binding protein 2 | 0.0185002 |
| PRKCE | protein kinase C, epsilon | 0.0184916 |
| RPS17 | ribosomal protein S17 | 0.0183002 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0182301 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0181212 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0176369 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0175607 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0175603 |
| CAVIN1 | caveolae associated protein 1 | 0.017018 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0165978 |
| RPL12 | ribosomal protein L12 | 0.0163877 |
| KLHL29 | kelch-like family member 29 | 0.0163584 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0162763 |
| IGF2 | insulin-like growth factor 2 | 0.0157544 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0156809 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0154606 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | 0.0153539 |
| GOLGB1 | golgin B1 | 0.0152205 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0151242 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0150977 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0150656 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0148901 |
| PCDH9 | protocadherin 9 | 0.0145134 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0144962 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0143984 |
| POLH | polymerase (DNA directed), eta | 0.0140858 |
| SDC4 | syndecan 4 | 0.0138581 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0137033 |
| RPS3 | ribosomal protein S3 | 0.0136766 |
| LRRC23 | leucine rich repeat containing 23 | 0.0136565 |
| RPS8 | ribosomal protein S8 | 0.013539 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.01353 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0131263 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0130664 |
| GTF2B | general transcription factor IIB | 0.0130579 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0129637 |
| PEG10 | paternally expressed 10 | 0.0128636 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.01281 |
| GPC5 | glypican 5 | 0.0126395 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0126236 |
| HLA-B | major histocompatibility complex, class I, B | 0.0124817 |
| C1S | complement component 1, s subcomponent | 0.0123027 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.011979 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0118922 |
| JUN | jun proto-oncogene | 0.0118736 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0117993 |
| BRD2 | bromodomain containing 2 | 0.0116413 |
| ARFGEF3 | ARFGEF family member 3 | 0.0116093 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0115058 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.011395 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0112852 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0112361 |
| RIGI | RNA sensor RIG-I | 0.0110677 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | -0.145856 |
| TMSB10 | thymosin beta 10 | -0.136924 |
| MMP12 | matrix metallopeptidase 12 | -0.134048 |
| VIM | vimentin | -0.109425 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.107728 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0999194 |
| PTMA | prothymosin, alpha | -0.0975064 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0972131 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0888387 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0828319 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0812662 |
| PTK2 | protein tyrosine kinase 2 | -0.0773256 |
| ZNF292 | zinc finger protein 292 | -0.0762065 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0737543 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0721466 |
| CD109 | CD109 molecule | -0.0718476 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0718257 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.071588 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.069948 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0674871 |
| RTN4 | reticulon 4 | -0.0666048 |
| ACTG1 | actin gamma 1 | -0.0611899 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.059241 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0584809 |
| POTEF | POTE ankyrin domain family, member F | -0.0583478 |
| VCL | vinculin | -0.0567178 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0565058 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0559538 |
| SPAG9 | sperm associated antigen 9 | -0.0557239 |
| ERBIN | erbb2 interacting protein | -0.0528988 |
| MT2A | metallothionein 2A | -0.0527303 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0518312 |
| TPM4 | tropomyosin 4 | -0.0509547 |
| NUP58 | nucleoporin 58 | -0.0508382 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0507742 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0505854 |
| QKI | QKI, KH domain containing, RNA binding | -0.049838 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0486291 |
| FTL | ferritin, light polypeptide | -0.047863 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0478119 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.047615 |
| SETD5 | SET domain containing 5 | -0.0469211 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0458034 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0456182 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0454692 |
| MED13L | mediator complex subunit 13-like | -0.045408 |
| DIAPH3 | diaphanous-related formin 3 | -0.0452462 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0451464 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0450683 |
| RBM39 | RNA binding motif protein 39 | -0.0450292 |
| ZNF207 | zinc finger protein 207 | -0.0450176 |
| PHIP | pleckstrin homology domain interacting protein | -0.0448826 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0444561 |
| RLF | rearranged L-myc fusion | -0.0442592 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0441488 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0436334 |
| LSAMP | limbic system-associated membrane protein | -0.0433853 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0433154 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0433035 |
| SBF2 | SET binding factor 2 | -0.0431689 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0430794 |
| ANXA2 | annexin A2 | -0.0430048 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.042783 |
| PGK1 | phosphoglycerate kinase 1 | -0.042463 |
| CENPF | centromere protein F, 350/400kDa | -0.0423111 |
| HELZ | helicase with zinc finger | -0.0420646 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0419894 |
| CDK17 | cyclin-dependent kinase 17 | -0.041842 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0418397 |
| NCKAP1 | NCK-associated protein 1 | -0.0416998 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0412612 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0412166 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0409033 |
| RNF145 | ring finger protein 145 | -0.0408573 |
| FN1 | fibronectin 1 | -0.0407737 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0407303 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0404661 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0403101 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0401186 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0398459 |
| RPL23 | ribosomal protein L23 | -0.0396277 |
| ECT2 | epithelial cell transforming 2 | -0.0390445 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0388948 |
| ATP13A3 | ATPase type 13A3 | -0.0388798 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0388549 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0387602 |
| SEPTIN7 | septin 7 | -0.0385095 |
| HMGA1 | high mobility group AT-hook 1 | -0.0380129 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0378124 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0377156 |
| MAP4 | microtubule-associated protein 4 | -0.0375336 |
| TXNRD1 | thioredoxin reductase 1 | -0.0373021 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0371835 |
| WDR45B | WD repeat domain 45B | -0.0369835 |
| DST | dystonin | -0.0366058 |
| USP3 | ubiquitin specific peptidase 3 | -0.0363775 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.035944 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0358767 |
| NRP2 | neuropilin 2 | -0.0357437 |
| OGA | O-GlcNAcase | -0.0356388 |
