| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.093216 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0656022 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0481037 |
| RPS12 | ribosomal protein S12 | 0.0430555 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0382818 |
| TMEM117 | transmembrane protein 117 | 0.0367197 |
| RPS2 | ribosomal protein S2 | 0.0366209 |
| YBX3 | Y box binding protein 3 | 0.0340899 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0330699 |
| CASZ1 | castor zinc finger 1 | 0.0323163 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0316213 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0289984 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0288417 |
| RPS19 | ribosomal protein S19 | 0.0286047 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0281384 |
| B2M | beta-2-microglobulin | 0.0276869 |
| TLN1 | talin 1 | 0.0270445 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.025176 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0248111 |
| RPS8 | ribosomal protein S8 | 0.0236179 |
| EPHA4 | EPH receptor A4 | 0.0231197 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0230689 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0230248 |
| IL32 | interleukin 32 | 0.0227003 |
| SULF2 | sulfatase 2 | 0.0215 |
| MT2A | metallothionein 2A | 0.0214528 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0209728 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0202815 |
| POLH | polymerase (DNA directed), eta | 0.0202251 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0199949 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0195913 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0195682 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0192357 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0185743 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.018403 |
| TAF3 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa | 0.0183466 |
| RPS27 | ribosomal protein S27 | 0.0183003 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0182058 |
| UBTF | upstream binding transcription factor, RNA polymerase I | 0.018045 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0179519 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0179289 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.0178566 |
| RPL36 | ribosomal protein L36 | 0.0173616 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0172259 |
| ANXA4 | annexin A4 | 0.0171496 |
| HLA-E | major histocompatibility complex, class I, E | 0.0169874 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0168848 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0167795 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0165854 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0165722 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 0.0164848 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0163465 |
| RNF213 | ring finger protein 213 | 0.0163171 |
| ATF3 | activating transcription factor 3 | 0.0163009 |
| ADAMTS17 | ADAM metallopeptidase with thrombospondin type 1 motif, 17 | 0.0162171 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0160799 |
| GDF15 | growth differentiation factor 15 | 0.0160269 |
| THRB | thyroid hormone receptor, beta | 0.0159017 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0158586 |
| CST3 | cystatin C | 0.0157856 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0156592 |
| FBXO32 | F-box protein 32 | 0.0156299 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0155459 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 0.0153586 |
| GNAS | GNAS complex locus | 0.0153545 |
| VIM | vimentin | 0.0153526 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0153191 |
| GLIS3 | GLIS family zinc finger 3 | 0.0153015 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0152688 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0152371 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0152327 |
| IKBIP | IKBKB interacting protein | 0.0150194 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0149833 |
| SFTPA2 | surfactant protein A2 | 0.01493 |
| ATXN1L | ataxin 1-like | 0.014927 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0149207 |
| TMC5 | transmembrane channel-like 5 | 0.0149121 |
| MED29 | mediator complex subunit 29 | 0.0148639 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0148198 |
| TPM3 | tropomyosin 3 | 0.0147444 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0146586 |
| MRPL33 | mitochondrial ribosomal protein L33 | 0.0145318 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0143568 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0142919 |
| REST | RE1-silencing transcription factor | 0.0141859 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0140946 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0139969 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0139378 |
| COL26A1 | collagen, type XXVI, alpha 1 | 0.0139331 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0139117 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.0137809 |
| SEPTIN11 | septin 11 | 0.0137547 |
| ACLY | ATP citrate lyase | 0.0137162 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0136513 |
| SELENOK | selenoprotein K | 0.0135719 |
| SYAP1 | synapse associated protein 1 | 0.0134737 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0133952 |
| MYO6 | myosin VI | 0.0133526 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.013314 |
| RPS29 | ribosomal protein S29 | 0.0132374 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.234 |
| PTMA | prothymosin, alpha | -0.206318 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.124817 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.12198 |
| ANXA2 | annexin A2 | -0.116619 |
| FLNB | filamin B, beta | -0.115907 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.112516 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.100354 |
| FAT1 | FAT atypical cadherin 1 | -0.0946979 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0946044 |
| LDHA | lactate dehydrogenase A | -0.0915578 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0900428 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0891337 |
| VCL | vinculin | -0.0871966 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0859032 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0854938 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0852972 |
| PRELID2 | PRELI domain containing 2 | -0.0789762 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0782213 |
| ITGA6 | integrin, alpha 6 | -0.0769233 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0747778 |
| TMSB10 | thymosin beta 10 | -0.074189 |
| ACTN4 | actinin, alpha 4 | -0.0739219 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0732861 |
| TNS4 | tensin 4 | -0.0700913 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0682773 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0665853 |
| RNF43 | ring finger protein 43 | -0.0636085 |
| ENO1 | enolase 1, (alpha) | -0.0629685 |
| ASPH | aspartate beta-hydroxylase | -0.0624113 |
| AHNAK | AHNAK nucleoprotein | -0.061368 |
| TPM4 | tropomyosin 4 | -0.0588373 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0573076 |
| PGK1 | phosphoglycerate kinase 1 | -0.0571996 |
| KRT18 | keratin 18, type I | -0.0557292 |
| GPHN | gephyrin | -0.0525073 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0523898 |
| NDRG1 | N-myc downstream regulated 1 | -0.0518186 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0513814 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0503711 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0503136 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0499008 |
| MYO1E | myosin IE | -0.049539 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.04926 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0492213 |
| ACTG1 | actin gamma 1 | -0.048912 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0482663 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.046113 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0458107 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0456963 |
| RNF217 | ring finger protein 217 | -0.0455506 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0453907 |
| SMYD3 | SET and MYND domain containing 3 | -0.0453151 |
| ATXN1 | ataxin 1 | -0.04518 |
| CCNY | cyclin Y | -0.0449636 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0445196 |
| CALB1 | calbindin 1, 28kDa | -0.0444347 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0438227 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0437229 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0435311 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0434968 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0429853 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0429314 |
| POTEF | POTE ankyrin domain family, member F | -0.0429015 |
| KRT8 | keratin 8, type II | -0.0420913 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0420515 |
| ANKRD17 | ankyrin repeat domain 17 | -0.041866 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0416808 |
| FHIT | fragile histidine triad | -0.0416235 |
| PALLD | palladin, cytoskeletal associated protein | -0.0414469 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0413614 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0411944 |
| PKM | pyruvate kinase, muscle | -0.0411429 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0407733 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.040113 |
| ECT2 | epithelial cell transforming 2 | -0.040017 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0397856 |
| TRIM2 | tripartite motif containing 2 | -0.0395843 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0394232 |
| SETD5 | SET domain containing 5 | -0.0392803 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0391183 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0390426 |
| ZNF292 | zinc finger protein 292 | -0.0390187 |
| DENND1A | DENN/MADD domain containing 1A | -0.0389298 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.03848 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0383676 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0382828 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0379078 |
| NFIA | nuclear factor I/A | -0.0377308 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0377117 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0376226 |
| USP34 | ubiquitin specific peptidase 34 | -0.03755 |
| PIGR | polymeric immunoglobulin receptor | -0.0374187 |
| FERMT1 | fermitin family member 1 | -0.0373312 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0367452 |
| MED13L | mediator complex subunit 13-like | -0.0365458 |
| EREG | epiregulin | -0.0363952 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0361825 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0361791 |
| PRSS3 | protease, serine, 3 | -0.036152 |
