| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0485335 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0403898 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0307736 |
| SYAP1 | synapse associated protein 1 | 0.0302378 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0293386 |
| CCNL1 | cyclin L1 | 0.0292523 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0280896 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0270791 |
| RPS2 | ribosomal protein S2 | 0.0269536 |
| TPM3 | tropomyosin 3 | 0.0251225 |
| VMP1 | vacuole membrane protein 1 | 0.0245291 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.024221 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0240857 |
| CAPRIN2 | caprin family member 2 | 0.0234446 |
| YBX3 | Y box binding protein 3 | 0.0221823 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0215397 |
| EGR1 | early growth response 1 | 0.0205782 |
| EREG | epiregulin | 0.0202229 |
| RPS12 | ribosomal protein S12 | 0.019805 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0190198 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0180984 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0176905 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.017533 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0172661 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0171985 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0171939 |
| RTN4 | reticulon 4 | 0.0171447 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0168616 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.016781 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0167455 |
| BRD2 | bromodomain containing 2 | 0.0163616 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0161137 |
| ANGPTL4 | angiopoietin-like 4 | 0.0160575 |
| PRKCE | protein kinase C, epsilon | 0.0160066 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0159967 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0157983 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0157364 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0153601 |
| SDC4 | syndecan 4 | 0.0153342 |
| TAPBP | TAP binding protein (tapasin) | 0.0150879 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.0148646 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0148509 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0148315 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0145805 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0145429 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0143628 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0143247 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0142748 |
| CEP128 | centrosomal protein 128kDa | 0.0141561 |
| ATXN1L | ataxin 1-like | 0.0139807 |
| SVIL | supervillin | 0.0139418 |
| ATF3 | activating transcription factor 3 | 0.0136133 |
| MT1X | metallothionein 1X | 0.0135869 |
| USP11 | ubiquitin specific peptidase 11 | 0.013576 |
| AREG | amphiregulin | 0.0135472 |
| GTF2B | general transcription factor IIB | 0.0134074 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.013405 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0133725 |
| TLN1 | talin 1 | 0.0132566 |
| SFTPA2 | surfactant protein A2 | 0.013149 |
| JMJD1C | jumonji domain containing 1C | 0.013089 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0129885 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0129579 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0129027 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.012885 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0127415 |
| SON | SON DNA binding protein | 0.0127029 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0127029 |
| RPS6 | ribosomal protein S6 | 0.0124724 |
| CRY1 | cryptochrome circadian clock 1 | 0.012437 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0121669 |
| ETNK1 | ethanolamine kinase 1 | 0.0120958 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0118876 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0117602 |
| CYCS | cytochrome c, somatic | 0.0116943 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0115967 |
| RECQL | RecQ helicase-like | 0.0115561 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0115261 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0114332 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0114055 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0112242 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0111889 |
| IPO7 | importin 7 | 0.0111842 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0111752 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0111593 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.011126 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0110449 |
| KLF6 | Kruppel-like factor 6 | 0.0109502 |
| MED29 | mediator complex subunit 29 | 0.01091 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.010792 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0107569 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0107314 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0106378 |
| FAM219A | family with sequence similarity 219, member A | 0.0105694 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0103873 |
| SGMS2 | sphingomyelin synthase 2 | 0.0103088 |
| ANKRD26 | ankyrin repeat domain 26 | 0.0102859 |
| RTTN | rotatin | 0.010227 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0100568 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.00995364 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.239244 |
| PTMA | prothymosin, alpha | -0.177986 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.1666 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154357 |
| CD44 | CD44 molecule (Indian blood group) | -0.143527 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.112607 |
| TMSB10 | thymosin beta 10 | -0.111638 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.103678 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102288 |
| FTL | ferritin, light polypeptide | -0.0800682 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0794911 |
| CANX | calnexin | -0.0781454 |
| TMSB4X | thymosin beta 4, X-linked | -0.0774359 |
| ACTG1 | actin gamma 1 | -0.0737219 |
| AHNAK | AHNAK nucleoprotein | -0.0723028 |
| POTEF | POTE ankyrin domain family, member F | -0.0717596 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0711454 |
| RPL35A | ribosomal protein L35a | -0.0707733 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0705172 |
| APP | amyloid beta (A4) precursor protein | -0.0699985 |
| LDHA | lactate dehydrogenase A | -0.067545 |
| DST | dystonin | -0.0670286 |
| RAI1 | retinoic acid induced 1 | -0.066597 |
| PGK1 | phosphoglycerate kinase 1 | -0.0655498 |
| EHBP1 | EH domain binding protein 1 | -0.0641008 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0566888 |
| FMNL2 | formin-like 2 | -0.0546097 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0542191 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0530105 |
| RPS8 | ribosomal protein S8 | -0.0521545 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0516251 |
| MYOF | myoferlin | -0.0508291 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0507917 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.049769 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.047781 |
| RPL31 | ribosomal protein L31 | -0.0442358 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0439547 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0437561 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0432312 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0425793 |
| EFNA5 | ephrin-A5 | -0.0415686 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0398259 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0394403 |
| ENO1 | enolase 1, (alpha) | -0.0393475 |
| CENPF | centromere protein F, 350/400kDa | -0.0392609 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0391469 |
| HDLBP | high density lipoprotein binding protein | -0.0391322 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0382672 |
| RPS23 | ribosomal protein S23 | -0.0380889 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0377844 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0377462 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0377079 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0373345 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0370629 |
| RPL37A | ribosomal protein L37a | -0.0365637 |
| INTS6 | integrator complex subunit 6 | -0.0362022 |
| RPS27A | ribosomal protein S27a | -0.0354034 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0352403 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0350169 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0343545 |
| RPL23 | ribosomal protein L23 | -0.0337906 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0337555 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.033716 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0336461 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0334744 |
| RPS24 | ribosomal protein S24 | -0.0334622 |
| CALR | calreticulin | -0.0328441 |
| RPL19 | ribosomal protein L19 | -0.0328052 |
| FNIP1 | folliculin interacting protein 1 | -0.0322185 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0321367 |
| EGFR | epidermal growth factor receptor | -0.032094 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0319503 |
| CMIP | c-Maf inducing protein | -0.0319145 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0317837 |
| ZNF217 | zinc finger protein 217 | -0.0316842 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0316365 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0315733 |
| WASF2 | WAS protein family, member 2 | -0.0312813 |
| TMEM123 | transmembrane protein 123 | -0.0310085 |
| RPS29 | ribosomal protein S29 | -0.0307269 |
| RIGI | RNA sensor RIG-I | -0.0306157 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0305786 |
| ANXA2 | annexin A2 | -0.0303006 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0300174 |
| RPL38 | ribosomal protein L38 | -0.0296516 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0295113 |
| RPS25 | ribosomal protein S25 | -0.0294974 |
| SRGN | serglycin | -0.0294664 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0294265 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0294205 |
| RACK1 | receptor for activated C kinase 1 | -0.0293206 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0292804 |
| EXOC4 | exocyst complex component 4 | -0.0289344 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0288405 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.028805 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0286663 |
| TP63 | tumor protein p63 | -0.0284935 |
| RPL7A | ribosomal protein L7a | -0.0283493 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0280929 |
| RPS5 | ribosomal protein S5 | -0.0280705 |
