| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.142966 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.103288 |
| EGR1 | early growth response 1 | 0.0904136 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0866377 |
| GRAMD1B | GRAM domain containing 1B | 0.0845909 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0834788 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0761268 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0738105 |
| STC1 | stanniocalcin 1 | 0.0630009 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0589367 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0551302 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0525351 |
| CES1 | carboxylesterase 1 | 0.0521564 |
| SMAD3 | SMAD family member 3 | 0.0484848 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0475523 |
| RPS6 | ribosomal protein S6 | 0.0466121 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0461068 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0420672 |
| MT2A | metallothionein 2A | 0.0413587 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0400951 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0398968 |
| ATP11A | ATPase, class VI, type 11A | 0.0396469 |
| PM20D1 | peptidase M20 domain containing 1 | 0.038521 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0383515 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0382238 |
| AREG | amphiregulin | 0.037203 |
| SLTM | SAFB-like, transcription modulator | 0.036146 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0353099 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0341948 |
| SMYD3 | SET and MYND domain containing 3 | 0.0337902 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0334719 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0319795 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0309128 |
| EZR | ezrin | 0.0303597 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0299126 |
| RPS2 | ribosomal protein S2 | 0.0295251 |
| FAM13A | family with sequence similarity 13, member A | 0.0285153 |
| PCBP2 | poly(rC) binding protein 2 | 0.0278215 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0275958 |
| TXNRD1 | thioredoxin reductase 1 | 0.0273967 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0268143 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.026558 |
| RBM25 | RNA binding motif protein 25 | 0.0262963 |
| SLK | STE20-like kinase | 0.0258477 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0255999 |
| GOLGA4 | golgin A4 | 0.0253101 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0252617 |
| MSN | moesin | 0.0250475 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0246647 |
| SYAP1 | synapse associated protein 1 | 0.0240969 |
| WWOX | WW domain containing oxidoreductase | 0.0239874 |
| TMF1 | TATA element modulatory factor 1 | 0.0235722 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0227562 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0222358 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0219642 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0218184 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0213283 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0211678 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0206951 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0203796 |
| VIM | vimentin | 0.020138 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.019844 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0196471 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0196221 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0194469 |
| RTN4 | reticulon 4 | 0.0188418 |
| DHFR | dihydrofolate reductase | 0.0188206 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0183404 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0182403 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0181715 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0181402 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0180679 |
| RPS12 | ribosomal protein S12 | 0.0178718 |
| TMEM45B | transmembrane protein 45B | 0.0176857 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0176584 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0176499 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0174996 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0172632 |
| EP400 | E1A binding protein p400 | 0.0171497 |
| PNN | pinin, desmosome associated protein | 0.0168155 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0165896 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0163354 |
| MLPH | melanophilin | 0.0163086 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0162271 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0162074 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0161381 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0160645 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.015762 |
| CEP290 | centrosomal protein 290kDa | 0.0157597 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0155635 |
| DTNA | dystrobrevin, alpha | 0.0155271 |
| YBX3 | Y box binding protein 3 | 0.0152994 |
| FOXP1 | forkhead box P1 | 0.0152805 |
| ATP13A3 | ATPase type 13A3 | 0.0152287 |
| CHMP1B | charged multivesicular body protein 1B | 0.0152173 |
| TPM3 | tropomyosin 3 | 0.0152032 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0151807 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0150691 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.01505 |
| MAGEA4 | melanoma antigen family A4 | 0.015001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.300453 |
| TMSB10 | thymosin beta 10 | -0.13171 |
| INTS6 | integrator complex subunit 6 | -0.128398 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.115352 |
| EGFR | epidermal growth factor receptor | -0.109537 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.109155 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.105513 |
| LAMC2 | laminin, gamma 2 | -0.0892843 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0858438 |
| ASPH | aspartate beta-hydroxylase | -0.0844338 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0825834 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.078048 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0760586 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0759615 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0720097 |
| LDHA | lactate dehydrogenase A | -0.071158 |
| ANXA2 | annexin A2 | -0.069777 |
| RNF213 | ring finger protein 213 | -0.0676081 |
| AHNAK | AHNAK nucleoprotein | -0.0675987 |
| LMO7 | LIM domain 7 | -0.0613307 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0582309 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0571614 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0571285 |
| HOMER1 | homer scaffolding protein 1 | -0.0563496 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0562599 |
| PKM | pyruvate kinase, muscle | -0.0547145 |
| RPS24 | ribosomal protein S24 | -0.054537 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0545037 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0540608 |
| NABP1 | nucleic acid binding protein 1 | -0.0537109 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0533938 |
| NDRG1 | N-myc downstream regulated 1 | -0.0523587 |
| ACTG1 | actin gamma 1 | -0.0522118 |
| CST3 | cystatin C | -0.0509489 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0496437 |
| FBXO11 | F-box protein 11 | -0.0494682 |
| SCEL | sciellin | -0.049235 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0490891 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0490213 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.047917 |
| ABLIM1 | actin binding LIM protein 1 | -0.0477451 |
| PTMA | prothymosin, alpha | -0.0472628 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0457583 |
| PGK1 | phosphoglycerate kinase 1 | -0.0454129 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0453118 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0449949 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0443932 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0443599 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0436189 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0428469 |
| GPC6 | glypican 6 | -0.0424048 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0422848 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0422357 |
| HDLBP | high density lipoprotein binding protein | -0.0419361 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0415974 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0415125 |
| WASF2 | WAS protein family, member 2 | -0.041487 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0409444 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0407415 |
| RPL35A | ribosomal protein L35a | -0.040698 |
| S100A10 | S100 calcium binding protein A10 | -0.0393379 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0390175 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0388007 |
| GM2A | GM2 ganglioside activator | -0.0386979 |
| SPAG9 | sperm associated antigen 9 | -0.038655 |
| RAB1A | RAB1A, member RAS oncogene family | -0.038305 |
| MORF4L2 | mortality factor 4 like 2 | -0.0379201 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.037857 |
| KRT8 | keratin 8, type II | -0.0375518 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0373697 |
| VCL | vinculin | -0.037159 |
| TOP1 | topoisomerase (DNA) I | -0.0371535 |
| H1-0 | H1.0 linker histone | -0.0365921 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0363306 |
| GNAS | GNAS complex locus | -0.0358711 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0356248 |
| FTL | ferritin, light polypeptide | -0.0350661 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0350332 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0349763 |
| USP53 | ubiquitin specific peptidase 53 | -0.0349294 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0345982 |
| RPL34 | ribosomal protein L34 | -0.0345891 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0342329 |
| UVRAG | UV radiation resistance associated | -0.0341448 |
| CANX | calnexin | -0.0341432 |
| WDR45B | WD repeat domain 45B | -0.0339517 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0338855 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0336709 |
| KCMF1 | potassium channel modulatory factor 1 | -0.033074 |
| HLA-B | major histocompatibility complex, class I, B | -0.0330507 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326448 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0319516 |
| PDE8A | phosphodiesterase 8A | -0.0317974 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0316483 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0316262 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.031543 |
| AEBP2 | AE binding protein 2 | -0.0315093 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0313591 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0312055 |
| BBX | bobby sox homolog (Drosophila) | -0.0309971 |
