| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Idarubicin (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.102541 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0924816 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0895632 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0560427 |
| CD44 | CD44 molecule (Indian blood group) | 0.0465366 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0426914 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0405998 |
| GOLGA4 | golgin A4 | 0.0400297 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0395643 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0341449 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0338895 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0337043 |
| SMAD3 | SMAD family member 3 | 0.0334933 |
| RND3 | Rho family GTPase 3 | 0.0330047 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0311817 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0299876 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.029484 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0293454 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0286204 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0273722 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0271308 |
| IL1R1 | interleukin 1 receptor, type I | 0.026052 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0253403 |
| ATP13A3 | ATPase type 13A3 | 0.0249777 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0248617 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0237179 |
| LOX | lysyl oxidase | 0.0236954 |
| STC1 | stanniocalcin 1 | 0.0233557 |
| RHCG | Rh family, C glycoprotein | 0.0227647 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0223699 |
| SEC24A | SEC24 family member A | 0.0222156 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.021979 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.021909 |
| NTN4 | netrin 4 | 0.0214592 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0205399 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0202252 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0196323 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0195922 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0195801 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0194957 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0187601 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.018675 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0186524 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0185106 |
| MYADM | myeloid-associated differentiation marker | 0.0176208 |
| SYAP1 | synapse associated protein 1 | 0.01712 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.017102 |
| DUSP16 | dual specificity phosphatase 16 | 0.0166109 |
| EGR1 | early growth response 1 | 0.0165018 |
| RUNX2 | runt-related transcription factor 2 | 0.016336 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0162535 |
| FAM107B | family with sequence similarity 107, member B | 0.0161088 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0160649 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0159577 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0156303 |
| CRY1 | cryptochrome circadian clock 1 | 0.0155816 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0154692 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0154297 |
| JUN | jun proto-oncogene | 0.0150495 |
| TPR | translocated promoter region, nuclear basket protein | 0.0149512 |
| EZR | ezrin | 0.0148479 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0140783 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0137989 |
| SLK | STE20-like kinase | 0.0137122 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0136206 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0133767 |
| SNX9 | sorting nexin 9 | 0.0133695 |
| AOPEP | aminopeptidase O (putative) | 0.013261 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0131565 |
| KSR1 | kinase suppressor of ras 1 | 0.0131051 |
| FRMD4A | FERM domain containing 4A | 0.0129563 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0129016 |
| TXLNG | taxilin gamma | 0.0128956 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0127824 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0126753 |
| VEGFA | vascular endothelial growth factor A | 0.0126631 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0125305 |
| MYO10 | myosin X | 0.0125004 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0124276 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0123271 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.012326 |
| FBXO32 | F-box protein 32 | 0.0121928 |
| NRG1 | neuregulin 1 | 0.0121717 |
| ZNF469 | zinc finger protein 469 | 0.0121629 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0121328 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0121146 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0120937 |
| ATF3 | activating transcription factor 3 | 0.0120439 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.0118673 |
| RPS2 | ribosomal protein S2 | 0.0118597 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0118048 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0117014 |
| RNF19B | ring finger protein 19B | 0.0116615 |
| CA12 | carbonic anhydrase XII | 0.0116495 |
| OPTN | optineurin | 0.0116125 |
| RAB8B | RAB8B, member RAS oncogene family | 0.011475 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0114013 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0113814 |
| CCDC88A | coiled-coil domain containing 88A | 0.0113635 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.01135 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.14945 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.145686 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.111761 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.110268 |
| GPC6 | glypican 6 | -0.102635 |
| MT2A | metallothionein 2A | -0.0980863 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0964345 |
| CDH13 | cadherin 13 | -0.0948107 |
| FN1 | fibronectin 1 | -0.0921032 |
| VIM | vimentin | -0.0859621 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0762805 |
| FAM20C | family with sequence similarity 20, member C | -0.0758523 |
| RPLP1 | ribosomal protein, large, P1 | -0.0654511 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0648862 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0642797 |
| FTL | ferritin, light polypeptide | -0.064152 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0640788 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0629167 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0616828 |
| PRELID2 | PRELI domain containing 2 | -0.0610371 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0567701 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0550115 |
| PTMA | prothymosin, alpha | -0.0549774 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0531997 |
| RPL35A | ribosomal protein L35a | -0.0481063 |
| GLCCI1 | glucocorticoid induced 1 | -0.0478326 |
| RPS19 | ribosomal protein S19 | -0.0460882 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0450822 |
| RPS24 | ribosomal protein S24 | -0.0446155 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0429482 |
| RPS21 | ribosomal protein S21 | -0.0428757 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0420955 |
| RPLP2 | ribosomal protein, large, P2 | -0.0420232 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0412517 |
| AHNAK | AHNAK nucleoprotein | -0.0411054 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0410024 |
| USP34 | ubiquitin specific peptidase 34 | -0.0383696 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0379232 |
| RPL32 | ribosomal protein L32 | -0.0378212 |
| RPL23 | ribosomal protein L23 | -0.0377559 |
| RPS29 | ribosomal protein S29 | -0.0354791 |
| ATXN1 | ataxin 1 | -0.0351205 |
| PKM | pyruvate kinase, muscle | -0.0349923 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0347227 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0341937 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0337153 |
| IER3 | immediate early response 3 | -0.0336393 |
| CDK14 | cyclin-dependent kinase 14 | -0.0330437 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.033019 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0327368 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0325265 |
| NDRG1 | N-myc downstream regulated 1 | -0.0324812 |
| RAD51B | RAD51 paralog B | -0.0319959 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0317833 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0317394 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0312824 |
| VCL | vinculin | -0.0305422 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0305277 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299124 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0298645 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0297382 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0296719 |
| RPS11 | ribosomal protein S11 | -0.0295797 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0291022 |
| KLF6 | Kruppel-like factor 6 | -0.0284793 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0283495 |
| RPL12 | ribosomal protein L12 | -0.0275825 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.027574 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0272764 |
| RPL19 | ribosomal protein L19 | -0.0271594 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0270477 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0270087 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.026975 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0266269 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0266253 |
| ZNF804A | zinc finger protein 804A | -0.0263391 |
| TMSB4X | thymosin beta 4, X-linked | -0.0262366 |
| CANX | calnexin | -0.0261839 |
| RPL31 | ribosomal protein L31 | -0.0260404 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0259434 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0259058 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0257267 |
| ACTG1 | actin gamma 1 | -0.0256593 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0255993 |
| CALR | calreticulin | -0.0253701 |
| RPL34 | ribosomal protein L34 | -0.0253034 |
| RPS8 | ribosomal protein S8 | -0.0248626 |
| HLA-B | major histocompatibility complex, class I, B | -0.0248622 |
| OGA | O-GlcNAcase | -0.0248243 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0244998 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0243238 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.024295 |
| RPLP0 | ribosomal protein, large, P0 | -0.0242578 |
| MTSS1 | metastasis suppressor 1 | -0.0242011 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0240438 |
| RPL36 | ribosomal protein L36 | -0.0238339 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0236359 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0234373 |
| SUMF1 | sulfatase modifying factor 1 | -0.0233023 |
| RPL11 | ribosomal protein L11 | -0.0232967 |
