| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC16 | mucin 16, cell surface associated | 0.0681115 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0631109 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0613004 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0612749 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0605725 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0592956 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0572818 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0571669 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0564714 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0560285 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.055618 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0555268 |
| SPAG9 | sperm associated antigen 9 | 0.0554294 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0554229 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.0549948 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0547181 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0532573 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0530695 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0501605 |
| PCBP2 | poly(rC) binding protein 2 | 0.0498338 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0483831 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0482761 |
| DUSP5 | dual specificity phosphatase 5 | 0.0482521 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0473634 |
| ITSN2 | intersectin 2 | 0.0467464 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0461762 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0458525 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0451245 |
| RND3 | Rho family GTPase 3 | 0.0449922 |
| TOP1 | topoisomerase (DNA) I | 0.0449294 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0445274 |
| KYNU | kynureninase | 0.0444941 |
| DENND1B | DENN/MADD domain containing 1B | 0.0441928 |
| BRD2 | bromodomain containing 2 | 0.0437241 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0434464 |
| LAMB3 | laminin, beta 3 | 0.0429854 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0429317 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0425709 |
| GPHN | gephyrin | 0.0418534 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0415498 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0406972 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0406852 |
| JAK1 | Janus kinase 1 | 0.0395608 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0390126 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0388653 |
| GDF15 | growth differentiation factor 15 | 0.0387046 |
| RIGI | RNA sensor RIG-I | 0.0385773 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0385271 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0380069 |
| SRPK2 | SRSF protein kinase 2 | 0.0379931 |
| ZNRF2 | zinc and ring finger 2, E3 ubiquitin protein ligase | 0.037963 |
| TLN1 | talin 1 | 0.0379284 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0378406 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0377777 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0375323 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0371825 |
| NECTIN4 | nectin cell adhesion molecule 4 | 0.0371109 |
| DENND4A | DENN/MADD domain containing 4A | 0.0366727 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0366595 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0364941 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.0362782 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0359158 |
| CDK6 | cyclin-dependent kinase 6 | 0.0354327 |
| CLIC4 | chloride intracellular channel 4 | 0.0353268 |
| COL5A2 | collagen, type V, alpha 2 | 0.0353104 |
| IL6ST | interleukin 6 signal transducer | 0.0352491 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0345511 |
| JUN | jun proto-oncogene | 0.0342666 |
| KRT17 | keratin 17, type I | 0.0341572 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0340722 |
| PRKCE | protein kinase C, epsilon | 0.0339837 |
| VIM | vimentin | 0.0339263 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0335618 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0335171 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0334437 |
| NUP58 | nucleoporin 58 | 0.0334388 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0333893 |
| SF1 | splicing factor 1 | 0.0333697 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0328428 |
| CCNL1 | cyclin L1 | 0.0328032 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0327896 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0327347 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0326524 |
| RPL12 | ribosomal protein L12 | 0.0324956 |
| MYOF | myoferlin | 0.0322082 |
| ASPH | aspartate beta-hydroxylase | 0.0321822 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0319466 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0317944 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0317852 |
| CDK8 | cyclin-dependent kinase 8 | 0.0316747 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0316486 |
| CALU | calumenin | 0.0314307 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0314229 |
| RAI14 | retinoic acid induced 14 | 0.0314109 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0314068 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0311086 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0310423 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0309601 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.030721 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0306917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.203191 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.127708 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126665 |
| ATOSA | atos homolog A | -0.119482 |
| LMO7 | LIM domain 7 | -0.112268 |
| MYO1E | myosin IE | -0.109189 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.102353 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0917003 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.083221 |
| PRELID2 | PRELI domain containing 2 | -0.0810509 |
| ANXA2 | annexin A2 | -0.0780488 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0767356 |
| TMSB10 | thymosin beta 10 | -0.0762934 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0759866 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0758135 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0756283 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0746872 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0744749 |
| SVIL | supervillin | -0.0738935 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0716849 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.070771 |
| ERBIN | erbb2 interacting protein | -0.0701817 |
| PTMA | prothymosin, alpha | -0.0643095 |
| NEBL | nebulette | -0.0631316 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0630759 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0627969 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0613446 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0597136 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0582294 |
| LOC112694756 | uncharaterized LOC112694756 | -0.056399 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0558388 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0531257 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0530484 |
| AHNAK | AHNAK nucleoprotein | -0.0512296 |
| RBM47 | RNA binding motif protein 47 | -0.0508076 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0497497 |
| CCNI | cyclin I | -0.047969 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.046758 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0466576 |
| JMJD1C | jumonji domain containing 1C | -0.0456149 |
| ZNF217 | zinc finger protein 217 | -0.0452926 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0444636 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0443154 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0433812 |
| VCL | vinculin | -0.0427487 |
| RORA | RAR-related orphan receptor A | -0.0425707 |
| FMN1 | formin 1 | -0.0423579 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0421448 |
| S100A10 | S100 calcium binding protein A10 | -0.0420403 |
| TXNIP | thioredoxin interacting protein | -0.0414218 |
| CDK12 | cyclin-dependent kinase 12 | -0.04134 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0410013 |
| PERP | PERP, TP53 apoptosis effector | -0.0403571 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0402824 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0401163 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0399026 |
| LAMC2 | laminin, gamma 2 | -0.0394332 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0394208 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0391559 |
| MYO5C | myosin VC | -0.0386441 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0382322 |
| S100A9 | S100 calcium binding protein A9 | -0.0379504 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0379466 |
| DENND1A | DENN/MADD domain containing 1A | -0.0378733 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0378365 |
| RPL34 | ribosomal protein L34 | -0.0374552 |
| POTEF | POTE ankyrin domain family, member F | -0.0371821 |
| FTL | ferritin, light polypeptide | -0.0367162 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0366816 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0365796 |
| INHBA | inhibin, beta A | -0.0364518 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0362212 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0356203 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0353796 |
| BPTF | bromodomain PHD finger transcription factor | -0.0351222 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0350252 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0347953 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0347769 |
| TJP2 | tight junction protein 2 | -0.0347447 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0346897 |
| DSG2 | desmoglein 2 | -0.0346435 |
| FOXO1 | forkhead box O1 | -0.0341507 |
| PLAUR | plasminogen activator, urokinase receptor | -0.033853 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0336179 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0333541 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0333486 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.032673 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0326669 |
| PSEN1 | presenilin 1 | -0.0326428 |
| TPM4 | tropomyosin 4 | -0.0326036 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0325703 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0319117 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0316112 |
| GPC6 | glypican 6 | -0.031509 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0314908 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0314894 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0313807 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.031331 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0313049 |
| PRSS23 | protease, serine, 23 | -0.0311294 |
