| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.149104 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0975028 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0963581 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0948167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0880043 |
| FTL | ferritin, light polypeptide | 0.0658332 |
| BRD2 | bromodomain containing 2 | 0.0658027 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0632244 |
| RPS6 | ribosomal protein S6 | 0.062508 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0616937 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0557715 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0544166 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0524424 |
| RPS2 | ribosomal protein S2 | 0.0505903 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0500015 |
| EZR | ezrin | 0.0484761 |
| GOLGA4 | golgin A4 | 0.0467208 |
| RBM25 | RNA binding motif protein 25 | 0.0432867 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0416601 |
| TMF1 | TATA element modulatory factor 1 | 0.0406224 |
| PCBP2 | poly(rC) binding protein 2 | 0.0403479 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0391702 |
| CCNL1 | cyclin L1 | 0.038913 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0382885 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0380858 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0376535 |
| TXNIP | thioredoxin interacting protein | 0.0376414 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0375436 |
| FAM13A | family with sequence similarity 13, member A | 0.0368418 |
| EGR1 | early growth response 1 | 0.0360268 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0359792 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0344528 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0344438 |
| MSN | moesin | 0.0329753 |
| EFNA5 | ephrin-A5 | 0.0323941 |
| PNN | pinin, desmosome associated protein | 0.031785 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.031476 |
| TPM3 | tropomyosin 3 | 0.0312829 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0309553 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0299044 |
| RTN4 | reticulon 4 | 0.0297463 |
| SGMS2 | sphingomyelin synthase 2 | 0.0295617 |
| VMP1 | vacuole membrane protein 1 | 0.0286091 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282679 |
| RNF145 | ring finger protein 145 | 0.0278632 |
| DTNA | dystrobrevin, alpha | 0.02755 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0270139 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0264882 |
| ATF4 | activating transcription factor 4 | 0.0264385 |
| RPS12 | ribosomal protein S12 | 0.0262595 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0253437 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0248358 |
| ATF3 | activating transcription factor 3 | 0.0246147 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0242307 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0242226 |
| GOLGB1 | golgin B1 | 0.0239348 |
| RND3 | Rho family GTPase 3 | 0.023679 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0234845 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0232592 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0231591 |
| STEAP4 | STEAP family member 4 | 0.0230883 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.02294 |
| HMGB2 | high mobility group box 2 | 0.0224904 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0223436 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0221127 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0219072 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0218314 |
| ZNF292 | zinc finger protein 292 | 0.0216026 |
| USP53 | ubiquitin specific peptidase 53 | 0.0215293 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0214694 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0209637 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0205278 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0204995 |
| WBP11 | WW domain binding protein 11 | 0.0203011 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0200354 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0195978 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0195119 |
| JUN | jun proto-oncogene | 0.0194915 |
| DUSP5 | dual specificity phosphatase 5 | 0.0194406 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0193717 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0193492 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0189916 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0189909 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0188883 |
| RBM39 | RNA binding motif protein 39 | 0.0188608 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0188213 |
| VEGFA | vascular endothelial growth factor A | 0.0186327 |
| FBXO32 | F-box protein 32 | 0.0186121 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0183995 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0182669 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0180254 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0178781 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0177888 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.017662 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0175144 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0173841 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0173372 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0172152 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0171986 |
| DUSP10 | dual specificity phosphatase 10 | 0.0171119 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.343039 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.202686 |
| TMSB10 | thymosin beta 10 | -0.127699 |
| LAMC2 | laminin, gamma 2 | -0.117403 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.115133 |
| ASPH | aspartate beta-hydroxylase | -0.111891 |
| TMSB4X | thymosin beta 4, X-linked | -0.102983 |
| ACTG1 | actin gamma 1 | -0.098858 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0973745 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.095009 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0933817 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0853219 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0845012 |
| AHNAK | AHNAK nucleoprotein | -0.0808054 |
| NAV2 | neuron navigator 2 | -0.0787958 |
| S100A6 | S100 calcium binding protein A6 | -0.077715 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0685599 |
| ANXA2 | annexin A2 | -0.0680273 |
| ERBIN | erbb2 interacting protein | -0.0667782 |
| CCND1 | cyclin D1 | -0.0652362 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0643552 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0635294 |
| KRT7 | keratin 7, type II | -0.0631784 |
| RPL35A | ribosomal protein L35a | -0.0615936 |
| TPM4 | tropomyosin 4 | -0.059918 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0577474 |
| PGK1 | phosphoglycerate kinase 1 | -0.0575951 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0562785 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0556812 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0544839 |
| CD2AP | CD2-associated protein | -0.0535413 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0533084 |
| CANX | calnexin | -0.0516483 |
| HMGA1 | high mobility group AT-hook 1 | -0.0515307 |
| LDHA | lactate dehydrogenase A | -0.0506165 |
| S100A10 | S100 calcium binding protein A10 | -0.0499768 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0491837 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0490432 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0485549 |
| RPL23 | ribosomal protein L23 | -0.0474549 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.047316 |
| CAB39 | calcium binding protein 39 | -0.0466217 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0454173 |
| POTEF | POTE ankyrin domain family, member F | -0.0450509 |
| EPCAM | epithelial cell adhesion molecule | -0.0439975 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0437311 |
| RPS24 | ribosomal protein S24 | -0.0432155 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0421531 |
| NDRG1 | N-myc downstream regulated 1 | -0.0416865 |
| KRT8 | keratin 8, type II | -0.04162 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0411242 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0407774 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0401048 |
| CTSB | cathepsin B | -0.0398568 |
| PLEC | plectin | -0.0388342 |
| ENO1 | enolase 1, (alpha) | -0.0387216 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0382059 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0379766 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0374384 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0370879 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0367818 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.036707 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0362844 |
| PTMA | prothymosin, alpha | -0.0361306 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0360938 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0357793 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.035668 |
| PKM | pyruvate kinase, muscle | -0.0354753 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0349462 |
| VCL | vinculin | -0.0348122 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0334565 |
| RPL34 | ribosomal protein L34 | -0.0333199 |
| KRT18 | keratin 18, type I | -0.0330873 |
| RNF213 | ring finger protein 213 | -0.0330293 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0327791 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0325084 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0324922 |
| PTK2 | protein tyrosine kinase 2 | -0.0323318 |
| LMO7 | LIM domain 7 | -0.0323035 |
| GNAS | GNAS complex locus | -0.0319091 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0316265 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0314281 |
| TMEM123 | transmembrane protein 123 | -0.0314162 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0313081 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0310853 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0307174 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0306536 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0302594 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302275 |
| OGA | O-GlcNAcase | -0.029929 |
| ZNF217 | zinc finger protein 217 | -0.0298194 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0297138 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0294877 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0292867 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0292744 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0292497 |
| FAM3C | family with sequence similarity 3, member C | -0.0289254 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0288772 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.028848 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0287686 |
