| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Idarubicin (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Idarubicin (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.261571 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.145118 |
| RPS2 | ribosomal protein S2 | 0.0818085 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0798637 |
| RPS16 | ribosomal protein S16 | 0.075165 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0743962 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0665689 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0649782 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0649758 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0640515 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0602012 |
| CENPF | centromere protein F, 350/400kDa | 0.0590174 |
| SEPTIN9 | septin 9 | 0.0575963 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0560434 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0543617 |
| RPS6 | ribosomal protein S6 | 0.0528165 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0517335 |
| BRD2 | bromodomain containing 2 | 0.0504206 |
| SMAD3 | SMAD family member 3 | 0.0486892 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0478957 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0457669 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0447564 |
| JMJD1C | jumonji domain containing 1C | 0.0445032 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0435624 |
| MT2A | metallothionein 2A | 0.0434775 |
| RPL4 | ribosomal protein L4 | 0.0410001 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0401344 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0401266 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0400667 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.0392712 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0390261 |
| NUP98 | nucleoporin 98kDa | 0.0386723 |
| VMP1 | vacuole membrane protein 1 | 0.0377908 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0376715 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0374049 |
| CCDC88A | coiled-coil domain containing 88A | 0.0370321 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0362649 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0354973 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0353914 |
| TPM3 | tropomyosin 3 | 0.0353483 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0351766 |
| PCBP2 | poly(rC) binding protein 2 | 0.0351705 |
| SSH2 | slingshot protein phosphatase 2 | 0.035116 |
| HELLS | helicase, lymphoid-specific | 0.0338034 |
| RPS12 | ribosomal protein S12 | 0.03306 |
| RAD51B | RAD51 paralog B | 0.0330479 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0329195 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.032681 |
| SMYD3 | SET and MYND domain containing 3 | 0.032524 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.032297 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.03196 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0319298 |
| MYADM | myeloid-associated differentiation marker | 0.0314711 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0312846 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0312841 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0298211 |
| ANGPTL4 | angiopoietin-like 4 | 0.0296024 |
| SET | SET nuclear proto-oncogene | 0.0295196 |
| DIAPH3 | diaphanous-related formin 3 | 0.0294534 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0292049 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0291103 |
| MKI67 | marker of proliferation Ki-67 | 0.0290953 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0287449 |
| STC2 | stanniocalcin 2 | 0.0285229 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0283722 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0282866 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0278693 |
| KIF5B | kinesin family member 5B | 0.0276843 |
| L1CAM | L1 cell adhesion molecule | 0.0275322 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0270323 |
| FBXO17 | F-box protein 17 | 0.0270112 |
| JUN | jun proto-oncogene | 0.0267818 |
| ANO6 | anoctamin 6 | 0.0267654 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.02664 |
| RBM39 | RNA binding motif protein 39 | 0.0264869 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0264292 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0263205 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262042 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0261109 |
| PHIP | pleckstrin homology domain interacting protein | 0.0261001 |
| ATF3 | activating transcription factor 3 | 0.0260159 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.02586 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0258237 |
| SLK | STE20-like kinase | 0.0256291 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0256012 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0252601 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0251914 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.025174 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0250734 |
| ABR | active BCR-related | 0.025047 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0249189 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0248814 |
| USP34 | ubiquitin specific peptidase 34 | 0.0248739 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0248201 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0247623 |
| EZR | ezrin | 0.024535 |
| CA8 | carbonic anhydrase VIII | 0.0245315 |
| CTBP2 | C-terminal binding protein 2 | 0.0244273 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0241567 |
| RPL37A | ribosomal protein L37a | 0.0238331 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.227742 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.168171 |
| CD44 | CD44 molecule (Indian blood group) | -0.127498 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.117452 |
| ACTN4 | actinin, alpha 4 | -0.114883 |
| AHNAK | AHNAK nucleoprotein | -0.109658 |
| TMSB10 | thymosin beta 10 | -0.106835 |
| SLC35F3 | solute carrier family 35, member F3 | -0.102285 |
| VIM | vimentin | -0.0781216 |
| TMEM123 | transmembrane protein 123 | -0.0759619 |
| ANXA2 | annexin A2 | -0.0743659 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0702832 |
| CANX | calnexin | -0.0694409 |
| EGFR | epidermal growth factor receptor | -0.0688729 |
| PGK1 | phosphoglycerate kinase 1 | -0.0620674 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0583784 |
| LDHA | lactate dehydrogenase A | -0.0579332 |
| VCL | vinculin | -0.0574493 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0568898 |
| MYOF | myoferlin | -0.0558556 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0550043 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0543448 |
| ZNF780B | zinc finger protein 780B | -0.0540293 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0521315 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.049981 |
| MED29 | mediator complex subunit 29 | -0.0493893 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0484973 |
| CALR | calreticulin | -0.0482033 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0460175 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0455166 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0453659 |
| RPS24 | ribosomal protein S24 | -0.0444755 |
| TPM1 | tropomyosin 1 (alpha) | -0.0443087 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0432614 |
| CD109 | CD109 molecule | -0.0420874 |
| MORF4L2 | mortality factor 4 like 2 | -0.0418947 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0411049 |
| TMEM41B | transmembrane protein 41B | -0.0406631 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0396936 |
| S100A6 | S100 calcium binding protein A6 | -0.0396244 |
| RPS5 | ribosomal protein S5 | -0.0391126 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0385802 |
| SBF2 | SET binding factor 2 | -0.037017 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0368391 |
| VDAC1 | voltage-dependent anion channel 1 | -0.036705 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0360613 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0338511 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0332332 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0327639 |
| PRSS23 | protease, serine, 23 | -0.032719 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0310926 |
| ZNF217 | zinc finger protein 217 | -0.0308861 |
| PDE10A | phosphodiesterase 10A | -0.0305823 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0304065 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0301701 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0299588 |
| H1-0 | H1.0 linker histone | -0.0296057 |
| RPL27A | ribosomal protein L27a | -0.0295604 |
| ENO1 | enolase 1, (alpha) | -0.0288706 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0287552 |
| HDLBP | high density lipoprotein binding protein | -0.0284252 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.028171 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.0278189 |
| S100A10 | S100 calcium binding protein A10 | -0.0275927 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0274293 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0269953 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.026681 |
| MOB1A | MOB kinase activator 1A | -0.0266601 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0263122 |
| RPS19 | ribosomal protein S19 | -0.0262722 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0262715 |
| CALU | calumenin | -0.02626 |
| POTEF | POTE ankyrin domain family, member F | -0.0260486 |
| FHL2 | four and a half LIM domains 2 | -0.025953 |
| RPL12 | ribosomal protein L12 | -0.0258932 |
| MEF2A | myocyte enhancer factor 2A | -0.0258836 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0258787 |
| RASAL2 | RAS protein activator like 2 | -0.0258294 |
| RPLP0 | ribosomal protein, large, P0 | -0.0258209 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.025716 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0255583 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0254757 |
| PERP | PERP, TP53 apoptosis effector | -0.0250532 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.025045 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0250358 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0249793 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.024735 |
| RPL35A | ribosomal protein L35a | -0.0245294 |
| DIAPH2 | diaphanous-related formin 2 | -0.0244486 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0244178 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0243416 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0242297 |
| CD47 | CD47 molecule | -0.0241634 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0241272 |
| ABLIM1 | actin binding LIM protein 1 | -0.0240101 |
| AFAP1 | actin filament associated protein 1 | -0.0240076 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0238127 |
| BSG | basigin (Ok blood group) | -0.0237716 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | -0.0236153 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.023588 |
